iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000003641.6	ENSGALT00000005766.6	ENSGALP00000005756.6
ENSGALG00000003641.6	ENSGALT00000073146.1	ENSGALP00000055545.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.80e-09	38.0	264	313

Active Site

Position(s)	Description	Evidence
681	Proton donor/acceptor	{ECO:0000256\|PIRSR:PIRSR602717-51}

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           k C  C+++g++ ++++ C+ C++ fH +C  ++  + +p+   wiC+ Cr 
   Q: 264  KTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPP-LTRMPKGM-WICQICRP 313
           68999******99*********************.9*****97.******85 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MVKLANPLYT EWILEAIKKV KKQKQRPSEE RICNAVSSSH GLDRKTVLEQ LELSVKDGTI 60
LKVSNKGLNS YKDPDNPGRI ALPKPRNHGK LDGKPNVDWN KLIKRAIEGL GESSGSSLKN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTAAAAC TCGCCAACCC CCTGTATACG GAGTGGATTT TGGAGGCAAT CAAAAAGGTA 60
AAGAAGCAAA AACAGCGTCC TTCAGAAGAG AGGATATGCA ATGCAGTGTC TTCATCACAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR002717--HAT_MYST-type
IPR005818--Histone_H1/H5_H15
IPR031280--KAT6A
IPR011991--WHTH_DNA-bd_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51504--H15
PS51726--MYST_HAT
PS50016--ZF_PHD_2

Pfam

PF01853--MOZ_SAS
PF00628--PHD

SMART

SM00526--H15
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0016607--C:nuclear speck
GO:0005730--C:nucleolus
GO:0000786--C:nucleosome
GO:0016605--C:PML body
GO:0003677--F:DNA binding
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0090398--P:cellular senescence
GO:0043966--P:histone H3 acetylation
GO:0030099--P:myeloid cell differentiation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0006334--P:nucleosome assembly
GO:0045893--P:positive regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001219	Ailuropoda melanoleuca	82.46	0.00e+00	2754.00
IUUC-Aca-004549	Anolis carolinensis	75.54	0.00e+00	1990.00
IUUC-Ame-010711	Astyanax mexicanus	62.20	1.00e-177	618.00
IUUC-Bta-013426	Bos taurus	79.32	0.00e+00	1743.00
IUUC-Cja-019124	Callithrix jacchus	81.41	0.00e+00	1791.00
IUUC-Cfa-021165	Canis familiaris	81.20	0.00e+00	2158.00
IUUC-Cpo-022332	Cavia porcellus	77.32	0.00e+00	2249.00
IUUC-Cne-026801	Cryptococcus neoformans	63.59	1.00e-73	271.00
IUUC-Dre-028624	Danio rerio	73.35	0.00e+00	1202.00
IUUC-Dno-029878	Dasypus novemcinctus	75.75	0.00e+00	1664.00
IUUC-Ete-032342	Echinops telfairi	84.09	0.00e+00	1659.00
IUUC-Eca-033925	Equus caballus	80.78	0.00e+00	2126.00
IUUC-Fca-035985	Felis catus	80.90	0.00e+00	2169.00
IUUC-Gmo-039182	Gadus morhua	72.42	0.00e+00	1194.00
IUUC-Gac-042131	Gasterosteus aculeatus	71.75	0.00e+00	1188.00
IUUC-Ggo-044664	Gorilla gorilla	80.81	0.00e+00	1784.00
IUUC-Hsa-046832	Homo sapiens	80.73	0.00e+00	1785.00
IUUC-Loc-052537	Lepisosteus oculatus	76.76	0.00e+00	1253.00
IUUC-Laf-053686	Loxodonta africana	81.77	0.00e+00	2150.00
IUUC-Mcc-055429	Macaca mulatta	81.14	0.00e+00	1791.00
IUUC-Mvi-060531	Microbotryum violaceum	54.91	4.00e-72	266.00
IUUC-Mmr-061249	Microcebus murinus	78.95	0.00e+00	1763.00
IUUC-Mdo-062826	Monodelphis domestica	81.08	0.00e+00	972.00
IUUC-Mmu-063474	Mus musculus	78.99	0.00e+00	1790.00
IUUC-Mpu-066585	Mustela putorius furo	80.56	0.00e+00	2155.00
IUUC-Mlu-066965	Myotis lucifugus	80.40	0.00e+00	2095.00
IUUC-Nle-069270	Nomascus leucogenys	80.81	0.00e+00	1785.00
IUUC-Opr-070963	Ochotona princeps	69.19	0.00e+00	1468.00
IUUC-Ont-071466	Oreochromis niloticus	71.67	0.00e+00	630.00
IUUC-Oan-073367	Ornithorhynchus anatinus	83.82	0.00e+00	2242.00
IUUC-Ocu-074100	Oryctolagus cuniculus	74.41	0.00e+00	1599.00
IUUC-Ola-087293	Oryzias latipes	73.91	0.00e+00	1188.00
IUUC-Oga-089052	Otolemur garnettii	87.35	0.00e+00	863.00
IUUC-Oar-089692	Ovis aries	77.00	0.00e+00	1684.00
IUUC-Ptr-091107	Pan troglodytes	80.73	0.00e+00	1776.00
IUUC-Pan-092524	Papio anubis	80.89	0.00e+00	1794.00
IUUC-Pfo-096641	Poecilia formosa	71.10	0.00e+00	1187.00
IUUC-Pab-098311	Pongo abelii	81.15	0.00e+00	1799.00
IUUC-Pca-100810	Procavia capensis	76.38	0.00e+00	1546.00
IUUC-Pgr-103522	Puccinia graminis	50.00	1.00e-68	254.00
IUUC-Pyt-104594	Pyrenophora triticirepentis	37.04	2.00e-46	180.00
IUUC-Rno-104990	Rattus norvegicus	77.75	0.00e+00	1731.00
IUUC-Sha-106816	Sarcophilus harrisii	82.99	0.00e+00	2207.00
IUUC-Sre-115066	Sporisorium reilianum	55.56	1.00e-77	285.00
IUUC-Tgu-116639	Taeniopygia guttata	92.56	0.00e+00	2950.00
IUUC-Tru-117956	Takifugu rubripes	59.10	3.00e-151	530.00
IUUC-Tni-119936	Tetraodon nigroviridis	74.28	0.00e+00	1225.00
IUUC-Tbe-127928	Tupaia belangeri	93.54	0.00e+00	1536.00
IUUC-Uma-129445	Ustilago maydis	56.84	2.00e-79	290.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence