iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xtr-132119

Ensembl Protein ID

ENSXETP00000012041.3

UniProt Accession

Q6GL77; UBXN1_XENTR

Genbank Protein ID

AAH74627.1; AAH75456.1

Protein Name

UBX domain-containing protein 1; SAPK substrate protein 1

Genbank Nucleotide ID

BC074627; BC075456

Gene Name

ubxn1; saks1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000005477.3	ENSXETT00000012041.3	ENSXETP00000012041.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	6.10e-09	35.9	6	42
ULD/UDP/UFD/UBX	4.60e-19	68.9	206	284

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 6    kleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
            le l+eMGF++++a +aL+a+ n  +e A+++L ++
   Q: 6    TLESLIEMGFSPSRAEKALAATgNQGIEPAMDWLVEH 42
           6999******************************986 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfve.yllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllv 79
           +++q+++q+Rl dG+ l ++F+++++l +++ +ve +  +    pF L+++fPrr +++e++++ lqe+gLvps++l+v
   Q: 206  EYDQCRIQVRLLDGSALSQTFRAREQLAAVRLYVElNWPGGAPGPFNLLTSFPRRVFTEEDMEKPLQELGLVPSAVLIV 284
           678**************************************************************************98 PP

Organism

Xenopus tropicalis

Functional Description
(View)

Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol. Involved in ubiquitin-proteasome systems (By similarity).

Protein Sequence
(Fasta)

MAECSTLESL IEMGFSPSRA EKALAATGNQ GIEPAMDWLV EHEDDPDIDE PSVVVPEDSD 60
SGTTDTQGMD TCEERLPLTE EEKEKQTKRM MELIAQKQKE REEREKRERI EQEKQRRKQG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAAGATCAG GAGCTACGGG AGCAGTTCGG GCAATGTGGG GAATGTAAAC AATACACTGG 60
GACAGCCAGC TGCCTTATGT TAATCGGGCT GTCCCGTGAA AAGCTGCCAA CTTGGGAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1185--Reference proteome

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50030--UBA
PS50033--UBX

Pfam

PF00627--UBA
PF00789--UBX

SMART

SM00165--UBA
SM00166--UBX

Gene Ontology

GO:0005737--C:cytoplasm

KEGG

xtr:448372

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001103	Aegilops tauschii	54.17	2.00e-09	57.00
IUUC-Aml-002325	Ailuropoda melanoleuca	62.93	5.00e-67	247.00
IUUC-Aca-004329	Anolis carolinensis	72.62	7.00e-52	196.00
IUUC-Ame-011399	Astyanax mexicanus	53.92	3.00e-70	258.00
IUUC-Bta-013151	Bos taurus	64.55	3.00e-74	271.00
IUUC-Bdi-014311	Brachypodium distachyon	50.88	3.00e-10	59.70
IUUC-Bra-017510	Brassica rapa	50.85	9.00e-11	61.20
IUUC-Cel-018300	Caenorhabditis elegans	31.75	1.00e-19	89.70
IUUC-Cja-019084	Callithrix jacchus	60.76	2.00e-58	219.00
IUUC-Cfa-020997	Canis familiaris	60.42	6.00e-55	207.00
IUUC-Cpo-021736	Cavia porcellus	58.84	4.00e-57	214.00
IUUC-Csa-024040	Chlorocebus sabaeus	61.87	4.00e-61	227.00
IUUC-Cho-024543	Choloepus hoffmanni	67.00	1.00e-45	175.00
IUUC-Cin-025719	Ciona intestinalis	43.92	6.00e-44	170.00
IUUC-Csv-025854	Ciona savignyi	43.19	8.00e-41	160.00
IUUC-Cne-027046	Cryptococcus neoformans	28.00	9.00e-18	84.00
IUUC-Cme-027235	Cyanidioschyzon merolae	47.73	6.00e-07	48.50
IUUC-Dre-027745	Danio rerio	55.70	1.00e-69	256.00
IUUC-Dno-029598	Dasypus novemcinctus	61.95	2.00e-65	242.00
IUUC-Dor-030917	Dipodomys ordii	60.80	2.00e-32	132.00
IUUC-Dme-032055	Drosophila melanogaster	45.20	4.00e-33	135.00
IUUC-Ete-032960	Echinops telfairi	54.67	3.00e-47	181.00
IUUC-Eca-034294	Equus caballus	63.58	4.00e-72	264.00
IUUC-Eeu-034906	Erinaceus europaeus	63.45	5.00e-67	247.00
IUUC-Fca-035653	Felis catus	60.55	2.00e-59	221.00
IUUC-Fso-038135	Fusarium solani	25.70	8.00e-06	44.30
IUUC-Gmo-038755	Gadus morhua	53.07	1.00e-67	249.00
IUUC-Gac-042481	Gasterosteus aculeatus	52.43	3.00e-62	231.00
IUUC-Gma-042684	Glycine max	56.25	2.00e-11	63.50
IUUC-Ggo-044821	Gorilla gorilla	60.90	2.00e-57	215.00
IUUC-Hsa-046797	Homo sapiens	62.21	7.00e-63	233.00
IUUC-Hvu-047779	Hordeum vulgare	50.00	1.00e-09	57.40
IUUC-Itr-048850	Ictidomys tridecemlineatus	63.76	2.00e-68	252.00
IUUC-Lch-049508	Latimeria chalumnae	51.52	8.00e-56	210.00
IUUC-Lpe-051322	Leersia perrieri	47.27	7.00e-10	58.20
IUUC-Laf-053932	Loxodonta africana	64.88	6.00e-78	283.00
IUUC-Mcc-055300	Macaca mulatta	62.75	3.00e-61	228.00
IUUC-Mor-056927	Magnaporthe oryzae	28.16	1.00e-09	56.60
IUUC-Mtr-058774	Medicago truncatula	41.25	6.00e-10	57.80
IUUC-Mla-059083	Melampsora laricipopulina	26.84	3.00e-12	65.90
IUUC-Mvi-060245	Microbotryum violaceum	37.50	5.00e-10	58.50
IUUC-Mmr-060979	Microcebus murinus	61.07	1.00e-61	229.00
IUUC-Mdo-062299	Monodelphis domestica	62.81	3.00e-66	244.00
IUUC-Mmu-063212	Mus musculus	65.44	2.00e-71	261.00
IUUC-Mac-065377	Musa acuminata	47.17	2.00e-10	56.60
IUUC-Mpu-066540	Mustela putorius furo	62.75	3.00e-68	251.00
IUUC-Mlu-067589	Myotis lucifugus	61.54	2.00e-68	251.00
IUUC-Nle-069045	Nomascus leucogenys	61.60	3.00e-44	171.00
IUUC-Opr-070772	Ochotona princeps	58.89	1.00e-53	203.00
IUUC-Ont-072006	Oreochromis niloticus	53.04	9.00e-62	229.00
IUUC-Oan-073244	Ornithorhynchus anatinus	47.33	4.00e-32	131.00
IUUC-Ocu-074333	Oryctolagus cuniculus	62.42	3.00e-64	238.00
IUUC-Oba-075451	Oryza barthii	50.94	2.00e-10	60.10
IUUC-Obr-076923	Oryza brachyantha	50.91	2.00e-11	63.20
IUUC-Ogl-077259	Oryza glaberrima	29.49	6.00e-12	65.10
IUUC-Ogu-078589	Oryza glumaepatula	50.94	2.00e-10	60.10
IUUC-Oin-079151	Oryza indica	50.94	2.00e-10	60.10
IUUC-Olo-080934	Oryza longistaminata	53.06	1.00e-10	60.80
IUUC-Ome-081253	Oryza meridionalis	50.94	2.00e-10	60.50
IUUC-Opu-083336	Oryza punctata	50.94	2.00e-10	59.70
IUUC-Oru-085235	Oryza rufipogon	50.94	2.00e-10	60.10
IUUC-Osa-085611	Oryza sativa	50.94	2.00e-10	60.10
IUUC-Ola-086781	Oryzias latipes	51.95	2.00e-59	222.00
IUUC-Oga-088429	Otolemur garnettii	62.75	4.00e-63	234.00
IUUC-Oar-089885	Ovis aries	63.88	1.00e-73	269.00
IUUC-Ptr-091315	Pan troglodytes	60.55	4.00e-57	214.00
IUUC-Pan-092885	Papio anubis	61.87	4.00e-61	227.00
IUUC-Psi-093299	Pelodiscus sinensis	64.09	4.00e-59	221.00
IUUC-Pma-094221	Petromyzon marinus	66.67	6.00e-27	112.00
IUUC-Ppa-095484	Physcomitrella patens	45.59	8.00e-10	57.80
IUUC-Pfo-096188	Poecilia formosa	52.46	1.00e-61	229.00
IUUC-Pab-097881	Pongo abelii	57.53	2.00e-59	222.00
IUUC-Pop-098863	Populus trichocarpa	52.73	7.00e-11	61.60
IUUC-Pca-100977	Procavia capensis	63.36	2.00e-66	245.00
IUUC-Ppe-101243	Prunus persica	58.00	7.00e-11	60.80
IUUC-Pva-102169	Pteropus vampyrus	61.11	2.00e-61	228.00
IUUC-Rno-105459	Rattus norvegicus	64.77	5.00e-71	260.00
IUUC-Sha-107526	Sarcophilus harrisii	63.42	2.00e-65	242.00
IUUC-Ssl-108389	Sclerotinia sclerotiorum	28.25	6.00e-07	48.50
IUUC-Smo-109210	Selaginella moellendorffii	45.28	2.00e-07	50.40
IUUC-Sit-110434	Setaria italica	30.60	4.00e-13	68.60
IUUC-Sar-112945	Sorex araneus	66.67	3.00e-44	171.00
IUUC-Sbi-114159	Sorghum bicolor	31.15	2.00e-13	69.70
IUUC-Sre-115055	Sporisorium reilianum	34.18	8.00e-06	44.30
IUUC-Ssc-116114	Sus scrofa	61.87	4.00e-63	234.00
IUUC-Tru-117839	Takifugu rubripes	54.10	9.00e-59	219.00
IUUC-Tsy-118813	Tarsius syrichta	68.50	9.00e-42	163.00
IUUC-Tni-120504	Tetraodon nigroviridis	57.09	5.00e-60	224.00
IUUC-Tae-124335	Triticum aestivum	54.17	2.00e-09	56.60
IUUC-Tur-126615	Triticum urartu	54.17	2.00e-09	56.60
IUUC-Tbe-128034	Tupaia belangeri	61.46	2.00e-62	232.00
IUUC-Ttr-128468	Tursiops truncatus	60.76	3.00e-61	228.00
IUUC-Uma-129569	Ustilago maydis	48.65	2.00e-05	43.10
IUUC-Vpa-130179	Vicugna pacos	56.60	2.00e-37	149.00
IUUC-Vvi-131064	Vitis vinifera	52.08	4.00e-09	55.80
IUUC-Xma-134067	Xiphophorus maculatus	52.79	3.00e-62	231.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence