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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063264
Ensembl Protein ID ENSMUSP00000026671.6
UniProt Accession A2ACM0; A2ACM0_MOUSE
Genbank Protein ID EDL34715.1
Protein Name Putative uncharacterized protein; Regulatory-associated protein of mTOR
Genbank Nucleotide ID AL669881
Gene Name Rptor; 4932417H02Rik; mCG_15044
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000025583.15 ENSMUST00000147781.7 ENSMUSP00000124366.1
ENSMUSG00000025583.15 ENSMUST00000026671.12 ENSMUSP00000026671.6
ENSMUSG00000025583.15 ENSMUST00000136662.7 ENSMUSP00000125293.1
ENSMUSG00000025583.15 ENSMUST00000124401.1 ENSMUSP00000125503.1
ENSMUSG00000025583.15 ENSMUST00000131217.1 ENSMUSP00000125667.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitecircBasemiRTarBasemicroRNA
TRANSFACRepTarmiRNAMapRAID2
Protein-protein Interaction
HINT
Post-translational Modifications (PTMs)
CPLMPHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.80e-14 53.8 1302 1330
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 4    dsvtclaf.sd.tllvsGsdDgtikvWDl 30
           + ++claf +  ++l++Gs+D  i v+++
   Q: 1302 GAISCLAFhPHwPHLAVGSNDYYISVYSV 1330
           679******888**************997 PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
MESEMLQSPL MGLGEEDEAD LTDWNLPLAF MKKRHCEKIE GSKSLAQSWR MKDRMKTVSV 60
ALVLCLNVGV DPPDVVKTTP CARLECWIDP LSMGPQKALE TIGANLQKQY ENWQPRARYK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063264|E3,WD_repeat|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGGACGGAAC ACCGAGCTCT ACGCCCTAGC AGGGGTAGAG CGGTGAGAAC GCTCGAAGAG 60
GTTTGGCTTA TTGGACGCGC CGTAGATAGC GGTGCATGCT GGGCCTTGGC AATATGGCGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063264|E3,WD_repeat|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR029030--Caspase-like_dom
IPR000357--HEAT
IPR004083--Raptor
IPR029347--Raptor_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50294--WD_REPEATS_REGION
Pfam

PF02985--HEAT
PF14538--Raptor_N
PF00400--WD40
SMART

SM01302--Raptor_N
SM00320--WD40
Gene Ontology

GO:0010494--C:cytoplasmic stress granule
GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0005765--C:lysosomal membrane
GO:0043025--C:neuronal cell body
GO:0005654--C:nucleoplasm
GO:0031931--C:TORC1 complex
GO:0030295--F:protein kinase activator activity
GO:0030291--F:protein serine/threonine kinase inhibitor activity
GO:0001030--F:RNA polymerase III type 1 promoter DNA binding
GO:0001031--F:RNA polymerase III type 2 promoter DNA binding
GO:0001032--F:RNA polymerase III type 3 promoter DNA binding
GO:0016049--P:cell growth
GO:0071230--P:cellular response to amino acid stimulus
GO:0031669--P:cellular response to nutrient levels
GO:0030307--P:positive regulation of cell growth
GO:0001938--P:positive regulation of endothelial cell proliferation
GO:1900087--P:positive regulation of G1/S transition of mitotic cell cycle
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0010800--P:positive regulation of peptidyl-threonine phosphorylation
GO:0071902--P:positive regulation of protein serine/threonine kinase activity
GO:0032008--P:positive regulation of TOR signaling
GO:0045945--P:positive regulation of transcription from RNA polymerase III promoter
GO:0008361--P:regulation of cell size
GO:0038202--P:TORC1 signaling
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000354 Aegilops tauschii 57.30 0.00e+00 676.00
IUUC-Aml-001499 Ailuropoda melanoleuca 96.48 0.00e+00 2556.00
IUUC-Atr-002704 Amborella trichopoda 50.72 0.00e+00 739.00
IUUC-Apl-003540 Anas platyrhynchos 94.52 0.00e+00 2518.00
IUUC-Aca-004449 Anolis carolinensis 96.41 0.00e+00 1373.00
IUUC-Aly-006524 Arabidopsis lyrata 58.86 0.00e+00 763.00
IUUC-Ath-007688 Arabidopsis thaliana 40.39 0.00e+00 885.00
IUUC-Ago-007709 Ashbya gossypii 56.47 5.00e-118 419.00
IUUC-Acl-008215 Aspergillus clavatus 55.69 0.00e+00 766.00
IUUC-Afl-008401 Aspergillus flavus 53.26 0.00e+00 767.00
IUUC-Afu-008797 Aspergillus fumigatus 57.34 0.00e+00 769.00
IUUC-Ani-009268 Aspergillus nidulans 57.34 0.00e+00 765.00
IUUC-Ang-009608 Aspergillus niger 55.77 0.00e+00 756.00
IUUC-Aor-009894 Aspergillus oryzae 53.26 0.00e+00 767.00
IUUC-Ate-010357 Aspergillus terreus 55.49 0.00e+00 767.00
IUUC-Ame-011186 Astyanax mexicanus 86.12 0.00e+00 2121.00
IUUC-Bgr-012085 Blumeria graminis 37.65 0.00e+00 810.00
IUUC-Bta-013422 Bos taurus 97.15 0.00e+00 2593.00
IUUC-Bci-013736 Botrytis cinerea 54.53 0.00e+00 713.00
IUUC-Bdi-015042 Brachypodium distachyon 41.05 0.00e+00 838.00
IUUC-Bol-016048 Brassica oleracea 59.27 0.00e+00 763.00
IUUC-Bra-016961 Brassica rapa 57.66 0.00e+00 778.00
IUUC-Cel-018321 Caenorhabditis elegans 45.31 2.00e-100 361.00
IUUC-Cja-018939 Callithrix jacchus 96.25 0.00e+00 2563.00
IUUC-Cfa-020898 Canis familiaris 96.78 0.00e+00 2573.00
IUUC-Cpo-021514 Cavia porcellus 98.58 0.00e+00 2607.00
IUUC-Cre-022818 Chlamydomonas reinhardtii 63.64 7.00e-111 393.00
IUUC-Csa-023314 Chlorocebus sabaeus 96.78 0.00e+00 2587.00
IUUC-Cin-025701 Ciona intestinalis 72.19 0.00e+00 1000.00
IUUC-Csv-026362 Ciona savignyi 71.79 0.00e+00 993.00
IUUC-Cgl-026561 Colletotrichum gloeosporioides 54.23 0.00e+00 679.00
IUUC-Cne-027009 Cryptococcus neoformans 47.87 0.00e+00 668.00
IUUC-Cme-027253 Cyanidioschyzon merolae 56.36 2.00e-137 484.00
IUUC-Dre-028485 Danio rerio 85.76 0.00e+00 2373.00
IUUC-Dno-029901 Dasypus novemcinctus 93.60 0.00e+00 2302.00
IUUC-Dor-030140 Dipodomys ordii 94.14 0.00e+00 2313.00
IUUC-Dse-031462 Dothistroma septosporum 50.00 0.00e+00 690.00
IUUC-Dme-031670 Drosophila melanogaster 64.09 0.00e+00 866.00
IUUC-Ete-032578 Echinops telfairi 74.16 0.00e+00 777.00
IUUC-Eca-034076 Equus caballus 97.23 0.00e+00 2592.00
IUUC-Eeu-035140 Erinaceus europaeus 92.92 0.00e+00 1167.00
IUUC-Fca-035651 Felis catus 96.93 0.00e+00 2580.00
IUUC-Fal-037244 Ficedula albicollis 94.08 0.00e+00 2475.00
IUUC-Fox-037742 Fusarium oxysporum 54.17 0.00e+00 683.00
IUUC-Fso-038369 Fusarium solani 55.34 0.00e+00 630.00
IUUC-Gmo-039007 Gadus morhua 79.45 0.00e+00 1821.00
IUUC-Ggr-039836 Gaeumannomyces graminis 53.69 0.00e+00 694.00
IUUC-Gga-041121 Gallus gallus 93.30 0.00e+00 2528.00
IUUC-Gac-041430 Gasterosteus aculeatus 87.61 0.00e+00 2340.00
IUUC-Gma-043160 Glycine max 42.20 0.00e+00 904.00
IUUC-Ggo-044934 Gorilla gorilla 98.41 0.00e+00 1416.00
IUUC-Hsa-045887 Homo sapiens 96.63 0.00e+00 2583.00
IUUC-Hvu-047823 Hordeum vulgare 58.18 0.00e+00 756.00
IUUC-Itr-048274 Ictidomys tridecemlineatus 99.28 0.00e+00 807.00
IUUC-Kpa-049399 Komagataella pastoris 59.26 1.00e-124 441.00
IUUC-Lch-050405 Latimeria chalumnae 91.09 0.00e+00 2474.00
IUUC-Lpe-050864 Leersia perrieri 64.81 2.00e-152 533.00
IUUC-Loc-051868 Lepisosteus oculatus 83.79 0.00e+00 2288.00
IUUC-Lma-052993 Leptosphaeria maculans 52.25 0.00e+00 752.00
IUUC-Laf-053339 Loxodonta africana 96.92 0.00e+00 1859.00
IUUC-Mcc-055591 Macaca mulatta 96.78 0.00e+00 2587.00
IUUC-Meu-056642 Macropus eugenii 86.82 0.00e+00 1221.00
IUUC-Mor-057204 Magnaporthe oryzae 53.38 0.00e+00 703.00
IUUC-Mpo-057532 Magnaporthe poae 53.54 0.00e+00 691.00
IUUC-Mtr-058553 Medicago truncatula 42.26 0.00e+00 912.00
IUUC-Mla-058907 Melampsora laricipopulina 44.72 1.00e-151 531.00
IUUC-Mga-059256 Meleagris gallopavo 94.99 0.00e+00 2536.00
IUUC-Mvi-060457 Microbotryum violaceum 49.79 0.00e+00 668.00
IUUC-Mmr-060874 Microcebus murinus 94.36 0.00e+00 2497.00
IUUC-Mdo-062436 Monodelphis domestica 94.16 0.00e+00 2517.00
IUUC-Mac-065524 Musa acuminata 41.54 0.00e+00 848.00
IUUC-Mpu-065899 Mustela putorius furo 95.34 0.00e+00 2351.00
IUUC-Mlu-067344 Myotis lucifugus 94.27 0.00e+00 1910.00
IUUC-Nfi-068615 Neosartorya fischeri 55.98 0.00e+00 768.00
IUUC-Ncr-068744 Neurospora crassa 53.67 0.00e+00 679.00
IUUC-Nle-069014 Nomascus leucogenys 96.18 0.00e+00 2566.00
IUUC-Opr-070548 Ochotona princeps 84.86 0.00e+00 1345.00
IUUC-Ont-072485 Oreochromis niloticus 88.10 0.00e+00 2357.00
IUUC-Oan-073253 Ornithorhynchus anatinus 91.64 0.00e+00 684.00
IUUC-Ocu-074290 Oryctolagus cuniculus 95.27 0.00e+00 820.00
IUUC-Oba-075130 Oryza barthii 56.69 0.00e+00 715.00
IUUC-Obr-076161 Oryza brachyantha 58.00 0.00e+00 754.00
IUUC-Ogl-077800 Oryza glaberrima 50.77 0.00e+00 751.00
IUUC-Ogu-078292 Oryza glumaepatula 64.66 5.00e-47 181.00
IUUC-Oin-080126 Oryza indica 46.45 0.00e+00 647.00
IUUC-Olo-080598 Oryza longistaminata 40.00 1.00e-34 141.00
IUUC-Ome-081293 Oryza meridionalis 38.41 3.00e-172 599.00
IUUC-Oni-082236 Oryza nivara 59.04 3.00e-84 307.00
IUUC-Opu-083423 Oryza punctata 57.44 0.00e+00 740.00
IUUC-Oru-085086 Oryza rufipogon 48.30 0.00e+00 685.00
IUUC-Osa-086012 Oryza sativa 41.53 0.00e+00 822.00
IUUC-Ola-086662 Oryzias latipes 86.23 0.00e+00 2023.00
IUUC-Olu-087760 Ostreococcus lucimarinus 57.49 0.00e+00 720.00
IUUC-Oga-088053 Otolemur garnettii 97.18 0.00e+00 2452.00
IUUC-Oar-089466 Ovis aries 93.08 0.00e+00 2558.00
IUUC-Ptr-090868 Pan troglodytes 96.03 0.00e+00 2575.00
IUUC-Pan-092259 Papio anubis 96.78 0.00e+00 2587.00
IUUC-Psi-093641 Pelodiscus sinensis 93.90 0.00e+00 2362.00
IUUC-Pno-094789 Phaeosphaeria nodorum 52.10 0.00e+00 714.00
IUUC-Ppa-095301 Physcomitrella patens 61.78 0.00e+00 763.00
IUUC-Pfo-096837 Poecilia formosa 86.25 0.00e+00 2353.00
IUUC-Pab-097545 Pongo abelii 95.24 0.00e+00 1269.00
IUUC-Pop-099059 Populus trichocarpa 62.35 0.00e+00 757.00
IUUC-Pca-100579 Procavia capensis 69.85 1.00e-177 617.00
IUUC-Ppe-101494 Prunus persica 58.40 0.00e+00 787.00
IUUC-Pva-103245 Pteropus vampyrus 85.41 0.00e+00 1814.00
IUUC-Pgr-103460 Puccinia graminis 47.29 7.00e-49 190.00
IUUC-Ptt-103797 Puccinia triticina 35.15 6.00e-65 243.00
IUUC-Pte-104367 Pyrenophora teres 52.95 0.00e+00 744.00
IUUC-Pyt-104771 Pyrenophora triticirepentis 50.22 0.00e+00 692.00
IUUC-Rno-104965 Rattus norvegicus 99.85 0.00e+00 2695.00
IUUC-Sce-106156 Saccharomyces cerevisiae 55.61 3.00e-119 424.00
IUUC-Sha-106474 Sarcophilus harrisii 94.22 0.00e+00 2009.00
IUUC-Sja-107888 Schizosaccharomyces japonicus 57.98 0.00e+00 774.00
IUUC-Spo-108057 Schizosaccharomyces pombe 56.79 0.00e+00 752.00
IUUC-Ssl-108423 Sclerotinia sclerotiorum 54.53 0.00e+00 717.00
IUUC-Smo-109059 Selaginella moellendorffii 55.93 0.00e+00 750.00
IUUC-Sit-109752 Setaria italica 57.80 0.00e+00 746.00
IUUC-Sly-110910 Solanum lycopersicum 56.58 0.00e+00 773.00
IUUC-Stu-112814 Solanum tuberosum 56.15 0.00e+00 765.00
IUUC-Sbi-113810 Sorghum bicolor 41.76 0.00e+00 867.00
IUUC-Sre-115168 Sporisorium reilianum 42.83 0.00e+00 685.00
IUUC-Ssc-115398 Sus scrofa 93.73 0.00e+00 1920.00
IUUC-Tgu-117361 Taeniopygia guttata 93.37 0.00e+00 2422.00
IUUC-Tsy-119587 Tarsius syrichta 98.93 0.00e+00 1155.00
IUUC-Tni-119757 Tetraodon nigroviridis 86.00 0.00e+00 2310.00
IUUC-Tca-121570 Theobroma cacao 62.77 0.00e+00 765.00
IUUC-Tre-122024 Trichoderma reesei 56.16 0.00e+00 639.00
IUUC-Tvi-122502 Trichoderma virens 55.67 0.00e+00 642.00
IUUC-Tae-125799 Triticum aestivum 58.18 0.00e+00 757.00
IUUC-Tme-127001 Tuber melanosporum 55.88 2.00e-154 540.00
IUUC-Ttr-129128 Tursiops truncatus 87.64 0.00e+00 2262.00
IUUC-Uma-129588 Ustilago maydis 44.93 0.00e+00 684.00
IUUC-Vda-129990 Verticillium dahliae 53.75 3.00e-180 626.00
IUUC-Vvi-131611 Vitis vinifera 42.20 0.00e+00 919.00
IUUC-Xtr-132727 Xenopus tropicalis 91.74 0.00e+00 2456.00
IUUC-Xma-133492 Xiphophorus maculatus 87.81 0.00e+00 2378.00
IUUC-Yli-134358 Yarrowia lipolytica 55.24 0.00e+00 696.00
IUUC-Zma-135723 Zea mays 57.62 0.00e+00 679.00
Created Date 25-Jun-2017

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