iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000007434.8	ENSRNOT00000075992.2	ENSRNOP00000068517.1
ENSRNOG00000007434.8	ENSRNOT00000076508.1	ENSRNOP00000068125.1
ENSRNOG00000007434.8	ENSRNOT00000041271.5	ENSRNOP00000040441.5

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	6.40e-26	91.1	14	119

Active Site

Position(s)	Description	Evidence
91	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk.e 88
           Rl+ke++el kdp+++++a+p ++ +l+ew++++ Gp+d+ ++ggv++ +i +p++YP+kPP++ +lt   ++ ++   k+Clsi + +
   Q: 14   RLMKEAAEL-KDPTDHYHAQPLED-NLFEWHFTVRGPPDSDFDGGVYHGRIVLPPEYPMKPPSIILLTA--NGRFEVGKKICLSISGhH 98
           9*******9.99************.9******************************************9..9999999********549 PP
   S: 89   eekWspalsvesvllsiqsll 109
           +e+W+p +s+++ ll+i+ ++
   Q: 99   PETWQPSWSIRTALLAIIGFM 119
           ******************998 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

METRYNLKSP AVKRLMKEAA ELKDPTDHYH AQPLEDNLFE WHFTVRGPPD SDFDGGVYHG 60
RIVLPPEYPM KPPSIILLTA NGRFEVGKKI CLSISGHHPE TWQPSWSIRT ALLAIIGFMP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGCGGCGC CGACGAGAGC GGCAGCGGGG AGGTCCGCCA TGGAGACCCG CTATAACCTG 60
AAGAGCCCGG GTGAGCCGGG TTGGGGCGGC GGGAGGGGAC CCGGGACTCA GGGCGCCGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:1904153--P:negative regulation of retrograde protein transport, ER to cytosol
GO:0018279--P:protein N-linked glycosylation via asparagine
GO:0042534--P:regulation of tumor necrosis factor biosynthetic process
GO:0007286--P:spermatid development
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001180	Aegilops tauschii	34.26	1.00e-34	140.00
IUUC-Aml-002404	Ailuropoda melanoleuca	97.18	1.00e-122	432.00
IUUC-Atr-002806	Amborella trichopoda	63.70	5.00e-55	207.00
IUUC-Apl-003507	Anas platyrhynchos	87.44	5.00e-105	374.00
IUUC-Aca-004697	Anolis carolinensis	85.97	4.00e-109	387.00
IUUC-Aly-005556	Arabidopsis lyrata	61.81	5.00e-54	204.00
IUUC-Ath-007477	Arabidopsis thaliana	61.11	1.00e-53	203.00
IUUC-Acl-008101	Aspergillus clavatus	56.46	4.00e-46	178.00
IUUC-Afl-008466	Aspergillus flavus	56.13	1.00e-44	173.00
IUUC-Afu-009109	Aspergillus fumigatus	53.46	2.00e-40	159.00
IUUC-Ani-009343	Aspergillus nidulans	53.85	7.00e-42	164.00
IUUC-Ang-009509	Aspergillus niger	57.94	1.00e-40	158.00
IUUC-Aor-010210	Aspergillus oryzae	56.13	1.00e-44	173.00
IUUC-Ate-010571	Aspergillus terreus	49.35	1.00e-38	154.00
IUUC-Ame-010806	Astyanax mexicanus	80.83	5.00e-86	310.00
IUUC-Bgr-012063	Blumeria graminis	45.45	6.00e-49	187.00
IUUC-Bta-012638	Bos taurus	95.26	2.00e-119	422.00
IUUC-Bci-013709	Botrytis cinerea	51.38	8.00e-49	187.00
IUUC-Bdi-014694	Brachypodium distachyon	60.42	2.00e-51	195.00
IUUC-Bol-015399	Brassica oleracea	60.27	2.00e-53	202.00
IUUC-Bra-017645	Brassica rapa	60.27	2.00e-53	202.00
IUUC-Cel-018452	Caenorhabditis elegans	59.61	9.00e-69	253.00
IUUC-Cja-019087	Callithrix jacchus	97.18	2.00e-122	432.00
IUUC-Cfa-020218	Canis familiaris	96.55	2.00e-115	408.00
IUUC-Cpo-022552	Cavia porcellus	97.18	4.00e-123	434.00
IUUC-Cre-022888	Chlamydomonas reinhardtii	60.14	6.00e-54	202.00
IUUC-Csa-024028	Chlorocebus sabaeus	97.18	1.00e-122	432.00
IUUC-Cho-024606	Choloepus hoffmanni	68.54	4.00e-78	284.00
IUUC-Cin-025631	Ciona intestinalis	70.05	7.00e-78	283.00
IUUC-Csv-026321	Ciona savignyi	68.95	5.00e-76	277.00
IUUC-Cgl-026755	Colletotrichum gloeosporioides	47.31	4.00e-49	188.00
IUUC-Cne-026839	Cryptococcus neoformans	45.95	3.00e-41	162.00
IUUC-Cme-027189	Cyanidioschyzon merolae	60.13	8.00e-45	174.00
IUUC-Dre-027569	Danio rerio	83.51	6.00e-91	327.00
IUUC-Dno-029214	Dasypus novemcinctus	96.24	5.00e-122	430.00
IUUC-Dor-030145	Dipodomys ordii	65.42	5.00e-34	138.00
IUUC-Dse-031537	Dothistroma septosporum	52.91	3.00e-52	198.00
IUUC-Ete-033083	Echinops telfairi	95.77	2.00e-121	428.00
IUUC-Eca-034179	Equus caballus	98.03	1.00e-117	416.00
IUUC-Eeu-035115	Erinaceus europaeus	79.25	2.00e-94	338.00
IUUC-Fca-036083	Felis catus	97.65	2.00e-123	435.00
IUUC-Fal-037289	Ficedula albicollis	86.47	1.00e-103	369.00
IUUC-Fox-038027	Fusarium oxysporum	58.04	1.00e-40	159.00
IUUC-Fso-038254	Fusarium solani	52.53	1.00e-50	192.00
IUUC-Ggr-039884	Gaeumannomyces graminis	55.92	1.00e-49	189.00
IUUC-Gga-041156	Gallus gallus	76.47	5.00e-105	374.00
IUUC-Gac-041807	Gasterosteus aculeatus	47.69	9.00e-38	150.00
IUUC-Gma-044356	Glycine max	63.27	4.00e-56	211.00
IUUC-Ggo-044450	Gorilla gorilla	97.65	2.00e-123	434.00
IUUC-Hsa-046496	Homo sapiens	97.65	3.00e-123	434.00
IUUC-Hvu-047328	Hordeum vulgare	59.72	8.00e-51	193.00
IUUC-Itr-048629	Ictidomys tridecemlineatus	98.12	2.00e-124	438.00
IUUC-Lch-050348	Latimeria chalumnae	86.29	4.00e-103	367.00
IUUC-Lpe-050862	Leersia perrieri	60.00	6.00e-52	197.00
IUUC-Loc-052465	Lepisosteus oculatus	79.12	3.00e-84	305.00
IUUC-Lma-053257	Leptosphaeria maculans	51.08	4.00e-53	201.00
IUUC-Laf-053830	Loxodonta africana	97.65	1.00e-123	435.00
IUUC-Mcc-054880	Macaca mulatta	97.18	8.00e-123	432.00
IUUC-Mor-057183	Magnaporthe oryzae	52.53	3.00e-49	188.00
IUUC-Mpo-057391	Magnaporthe poae	55.63	3.00e-50	191.00
IUUC-Mtr-058479	Medicago truncatula	61.90	2.00e-55	209.00
IUUC-Mga-059321	Meleagris gallopavo	94.41	5.00e-101	360.00
IUUC-Mvi-060366	Microbotryum violaceum	59.48	2.00e-50	192.00
IUUC-Mmr-061717	Microcebus murinus	97.54	1.00e-116	412.00
IUUC-Mdo-061865	Monodelphis domestica	86.43	5.00e-109	387.00
IUUC-Mmu-064049	Mus musculus	98.59	4.00e-124	437.00
IUUC-Mac-064669	Musa acuminata	58.90	5.00e-52	197.00
IUUC-Mpu-066177	Mustela putorius furo	96.97	2.00e-113	401.00
IUUC-Mlu-067037	Myotis lucifugus	95.57	1.00e-114	405.00
IUUC-Nfi-068283	Neosartorya fischeri	52.83	9.00e-43	167.00
IUUC-Ncr-068645	Neurospora crassa	46.29	1.00e-48	186.00
IUUC-Nle-069166	Nomascus leucogenys	97.18	8.00e-123	433.00
IUUC-Ont-072096	Oreochromis niloticus	73.25	9.00e-96	343.00
IUUC-Oan-073369	Ornithorhynchus anatinus	90.78	5.00e-109	387.00
IUUC-Ocu-074815	Oryctolagus cuniculus	97.18	1.00e-123	436.00
IUUC-Oba-075649	Oryza barthii	44.87	2.00e-52	199.00
IUUC-Obr-076169	Oryza brachyantha	60.69	1.00e-52	199.00
IUUC-Ogl-077144	Oryza glaberrima	44.87	2.00e-52	199.00
IUUC-Ogu-078255	Oryza glumaepatula	60.00	6.00e-52	197.00
IUUC-Oin-079510	Oryza indica	60.69	6.00e-51	194.00
IUUC-Olo-080589	Oryza longistaminata	46.77	1.00e-45	176.00
IUUC-Ome-081849	Oryza meridionalis	55.06	5.00e-49	187.00
IUUC-Oni-082959	Oryza nivara	60.00	7.00e-52	197.00
IUUC-Opu-083736	Oryza punctata	60.69	7.00e-52	197.00
IUUC-Oru-084215	Oryza rufipogon	60.00	6.00e-52	197.00
IUUC-Osa-085722	Oryza sativa	60.00	6.00e-52	197.00
IUUC-Ola-086717	Oryzias latipes	82.42	5.00e-91	327.00
IUUC-Olu-087750	Ostreococcus lucimarinus	66.06	3.00e-41	159.00
IUUC-Oga-088848	Otolemur garnettii	80.75	2.00e-98	351.00
IUUC-Oar-090134	Ovis aries	97.54	2.00e-117	415.00
IUUC-Ptr-091314	Pan troglodytes	97.65	2.00e-123	434.00
IUUC-Pan-092103	Papio anubis	97.18	1.00e-122	432.00
IUUC-Psi-093668	Pelodiscus sinensis	86.34	7.00e-102	363.00
IUUC-Pno-094982	Phaeosphaeria nodorum	56.38	1.00e-48	186.00
IUUC-Ppa-095836	Physcomitrella patens	62.11	9.00e-59	220.00
IUUC-Pfo-096964	Poecilia formosa	85.64	7.00e-98	350.00
IUUC-Pab-097857	Pongo abelii	97.18	5.00e-123	433.00
IUUC-Pop-099025	Populus trichocarpa	63.01	1.00e-55	209.00
IUUC-Pca-101108	Procavia capensis	94.03	4.00e-72	264.00
IUUC-Ppe-101444	Prunus persica	61.38	3.00e-54	204.00
IUUC-Pva-102297	Pteropus vampyrus	78.87	6.00e-93	333.00
IUUC-Pte-104112	Pyrenophora teres	54.27	5.00e-52	197.00
IUUC-Pyt-104824	Pyrenophora triticirepentis	56.06	7.00e-44	170.00
IUUC-Sha-107324	Sarcophilus harrisii	92.02	3.00e-116	411.00
IUUC-Smo-109549	Selaginella moellendorffii	68.75	3.00e-60	225.00
IUUC-Sit-110794	Setaria italica	60.00	2.00e-51	195.00
IUUC-Sly-111585	Solanum lycopersicum	64.19	6.00e-57	214.00
IUUC-Stu-111996	Solanum tuberosum	64.19	9.00e-57	213.00
IUUC-Sar-113063	Sorex araneus	96.53	1.00e-115	409.00
IUUC-Sbi-114593	Sorghum bicolor	60.00	2.00e-51	195.00
IUUC-Sre-115043	Sporisorium reilianum	52.51	2.00e-50	192.00
IUUC-Ssc-115523	Sus scrofa	96.71	4.00e-122	430.00
IUUC-Tgu-116966	Taeniopygia guttata	89.34	4.00e-106	377.00
IUUC-Tru-117737	Takifugu rubripes	71.06	3.00e-95	341.00
IUUC-Tsy-119190	Tarsius syrichta	100.00	1.00e-61	229.00
IUUC-Tni-120283	Tetraodon nigroviridis	94.59	2.00e-40	155.00
IUUC-Tca-120992	Theobroma cacao	64.38	5.00e-56	211.00
IUUC-Tre-122028	Trichoderma reesei	48.39	2.00e-49	189.00
IUUC-Tvi-122637	Trichoderma virens	54.04	1.00e-50	193.00
IUUC-Tae-122793	Triticum aestivum	59.72	6.00e-51	194.00
IUUC-Tme-126962	Tuber melanosporum	42.34	2.00e-51	195.00
IUUC-Tbe-127743	Tupaia belangeri	96.04	2.00e-115	408.00
IUUC-Ttr-129193	Tursiops truncatus	97.03	8.00e-116	409.00
IUUC-Uma-129586	Ustilago maydis	47.83	1.00e-49	190.00
IUUC-Vda-129959	Verticillium dahliae	54.43	2.00e-50	192.00
IUUC-Vpa-130404	Vicugna pacos	97.03	5.00e-116	410.00
IUUC-Vvi-130893	Vitis vinifera	62.33	5.00e-55	207.00
IUUC-Xtr-131832	Xenopus tropicalis	83.01	2.00e-98	352.00
IUUC-Zma-135443	Zea mays	60.42	9.00e-52	196.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence