iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037391

Ensembl Protein ID

ENSFALP00000008985.1

UniProt Accession

U3K1T1; U3K1T1_FICAL

Genbank Protein ID

ENSFALP00000008985

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01000153

Gene Name

FBXW4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000008613.1	ENSFALT00000009023.1	ENSFALP00000008985.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-22	79.0	187	220
UBD/Beta-Prp	4.00e-42	144.1	257	394

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           H+ +v+c++f+++l+vsGs+D t kvW+l+tg++
   Q: 187  HEQEVNCVDFQGGLIVSGSRDRTAKVWSLSTGRV 220
           99********669*****************9985 PP

UBD/Beta-Prp

   S: 160  tvrlWdlktgkllrtl.tgghtdsvysls.fdsngkelvsgsldgtvklwdlq..tgecvrtlng.htdnvksvrfspnderlvsgs.s 242
            +r+Wdl++g+ll+ l t + ++    l+ f ++   l+s+++d+++++wd++  t +cv+++++ h++  ++vr + +++ ++sgs  
   Q: 257  PLRIWDLESGQLLTCLgT-DFHRGAGVLDvFYETPSLLLSCGYDTYIRYWDIRtsTRKCVQEWEEpHDSALYCVRSD-RNHMIASGSsY 343
           58**************54.45555555554888889*****************9999*******9899999999988.99999999978 PP
   S: 243  DgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwkl 294
            g++r+Wd+r+  +l+++ l+  s+++v +l+f+  +l+++ + s ++++++
   Q: 344  YGVVRLWDKRQTRCLQSFHLSSPSSSPVYCLRFSTTHLYAALA-SALHVLDF 394
           9*********************************999988755.55666655 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

SRAASPPSPL WALPEELLLL ICSYLDAQAL GRLAQVCRRL RFLSSRDAYL LHGQSLIFSL 60
SGGFSQMGVT DVRAAGIPVK ERVKVSQNWR HGCCRRETVL KWKCNLMPWM ELDGEYLYLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCCGGGCCG CCTCCCCCCC CTCCCCGCTC TGGGCCTTAC CTGAGGAGCT GCTGCTCCTC 60
ATCTGCTCCT ACCTGGACGC GCAGGCCTTG GGCCGCCTGG CCCAGGTCTG CCGCCGCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0732--Signal
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR001810--F-box_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0051216--P:cartilage development
GO:0042733--P:embryonic digit morphogenesis
GO:0002053--P:positive regulation of mesenchymal cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002129	Ailuropoda melanoleuca	68.80	1.00e-148	519.00
IUUC-Apl-003837	Anas platyrhynchos	95.96	0.00e+00	627.00
IUUC-Aca-004776	Anolis carolinensis	77.72	2.00e-156	545.00
IUUC-Ame-010651	Astyanax mexicanus	64.53	2.00e-121	428.00
IUUC-Bta-013495	Bos taurus	68.27	1.00e-139	488.00
IUUC-Cja-018901	Callithrix jacchus	67.84	9.00e-137	479.00
IUUC-Cfa-021251	Canis familiaris	68.53	7.00e-148	517.00
IUUC-Cpo-021750	Cavia porcellus	72.10	4.00e-137	480.00
IUUC-Csa-024026	Chlorocebus sabaeus	67.84	3.00e-144	504.00
IUUC-Cho-024496	Choloepus hoffmanni	51.89	4.00e-97	347.00
IUUC-Cin-025142	Ciona intestinalis	30.23	2.00e-27	115.00
IUUC-Csv-025883	Ciona savignyi	36.07	1.00e-64	240.00
IUUC-Dre-027447	Danio rerio	60.52	6.00e-133	466.00
IUUC-Dno-029572	Dasypus novemcinctus	63.36	1.00e-116	413.00
IUUC-Dor-030982	Dipodomys ordii	62.16	2.00e-126	445.00
IUUC-Ete-032917	Echinops telfairi	71.96	7.00e-139	486.00
IUUC-Eca-033969	Equus caballus	68.38	1.00e-138	485.00
IUUC-Eeu-034850	Erinaceus europaeus	64.59	4.00e-129	454.00
IUUC-Fca-036182	Felis catus	66.93	5.00e-143	500.00
IUUC-Gmo-038632	Gadus morhua	57.29	2.00e-121	428.00
IUUC-Gga-040783	Gallus gallus	89.47	0.00e+00	649.00
IUUC-Gac-042314	Gasterosteus aculeatus	55.13	4.00e-99	354.00
IUUC-Ggo-044739	Gorilla gorilla	68.11	6.00e-144	503.00
IUUC-Hsa-046705	Homo sapiens	68.11	6.00e-137	479.00
IUUC-Itr-048014	Ictidomys tridecemlineatus	72.03	7.00e-122	429.00
IUUC-Loc-052397	Lepisosteus oculatus	68.57	4.00e-137	480.00
IUUC-Laf-054544	Loxodonta africana	71.69	2.00e-138	484.00
IUUC-Meu-056363	Macropus eugenii	61.32	9.00e-95	339.00
IUUC-Mga-059275	Meleagris gallopavo	95.34	0.00e+00	626.00
IUUC-Mmr-060906	Microcebus murinus	67.57	4.00e-143	501.00
IUUC-Mdo-062400	Monodelphis domestica	76.47	1.00e-161	562.00
IUUC-Mmu-063556	Mus musculus	69.19	2.00e-144	504.00
IUUC-Mpu-066500	Mustela putorius furo	68.53	4.00e-148	517.00
IUUC-Mlu-068074	Myotis lucifugus	71.34	1.00e-137	481.00
IUUC-Nle-069601	Nomascus leucogenys	68.11	4.00e-144	503.00
IUUC-Opr-070904	Ochotona princeps	61.40	4.00e-98	350.00
IUUC-Ont-072679	Oreochromis niloticus	57.22	2.00e-115	408.00
IUUC-Oan-073434	Ornithorhynchus anatinus	68.95	2.00e-75	275.00
IUUC-Ocu-074649	Oryctolagus cuniculus	68.11	4.00e-143	500.00
IUUC-Ola-087336	Oryzias latipes	49.36	2.00e-94	338.00
IUUC-Oga-088590	Otolemur garnettii	67.03	3.00e-135	474.00
IUUC-Oar-090178	Ovis aries	66.40	4.00e-135	474.00
IUUC-Pan-092881	Papio anubis	67.84	2.00e-144	504.00
IUUC-Pfo-096176	Poecilia formosa	55.61	3.00e-105	374.00
IUUC-Pab-098285	Pongo abelii	68.11	6.00e-144	504.00
IUUC-Pca-100888	Procavia capensis	66.13	2.00e-134	472.00
IUUC-Pva-102184	Pteropus vampyrus	58.11	6.00e-113	400.00
IUUC-Rno-105668	Rattus norvegicus	67.30	9.00e-142	496.00
IUUC-Sha-106629	Sarcophilus harrisii	81.45	2.00e-152	531.00
IUUC-Ssc-116183	Sus scrofa	69.60	5.00e-150	524.00
IUUC-Tgu-116630	Taeniopygia guttata	92.01	0.00e+00	711.00
IUUC-Tru-118761	Takifugu rubripes	52.96	1.00e-111	395.00
IUUC-Tni-120651	Tetraodon nigroviridis	53.47	2.00e-62	231.00
IUUC-Ttr-128582	Tursiops truncatus	68.80	8.00e-139	486.00
IUUC-Vpa-130431	Vicugna pacos	58.77	2.00e-69	255.00
IUUC-Xtr-132655	Xenopus tropicalis	71.31	2.00e-152	531.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence