iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000004796.3	ENSCPOT00000022341.1	ENSCPOP00000016030.1
ENSCPOG00000004796.3	ENSCPOT00000004847.2	ENSCPOP00000004316.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.40e-70	238.1	1893	2238

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           +Gl+Nlg+tCY+ S++Q+L++ipe r+++++ k++e++       ++++ l +lqk+f+ l++s+ ka++pr + k+  + ++ +++
   Q: 1893 VGLTNLGATCYLASTIQQLYMIPEARQAVFTaKYSEDM-------KHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNT 1972
           6******************************3444444.......4568899*********************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
            eq+D  Ef++ l+ ++ee                               + k++++ lF+g ++++++ l+c++vs++ e+f+++ 
   Q: 1973 GEQKDMTEFFTDLITKIEEMS----------------------------PELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVR 2031
           *****************9977............................567899******************************** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLd 260
           ++v + +     ++ ++L++ t +++leg+n+y c++c kk++aek+  +kklP++L+++ +R++f+  ++++ek+n++++fpl+Ld
   Q: 2032 CQVADMK-----NIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLD 2113
           *******.....9************************************************************************** PP
   S: 261  lspfcts................peekqkekkkYeLiavvvHsGslssGHYvayvkn.......ekgkWllfdDskVtevkeeevle 324
           ++p++++                + +k++e+++Y+Li+v vH+G++++GHY++++++       +++kW+lf+D +V++ + ++  +
   Q: 2114 MTPYTEDflmgksdrkegfkeasDHSKDTESYEYDLIGVTVHTGTADGGHYYSFIRDivnphayKNNKWYLFNDAEVKPFDSAQLAS 2200
           **********99999999999886666677***************************99999988999******************9 PP
   S: 325  etg........................staYvlfYkrr 338
           e+                         ++aY+lfYkr+
   Q: 2201 ECFggemttktydsvtdkfmdfsfektHSAYMLFYKRM 2238
           7779********************************96 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MCENCADLWK VLNEISDIEG GDGLQLRKEH TLKIFAYINS WTQRQCLCCF KEYKHLEIFN 60
QVVCALINLV IAQVQVLRDQ LCKHCTINVD STWQDESNQA EEPLNIDREC NEGSAERQKS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGCGAGA ACTGCGCAGA CCTGGGTGGA AGGTGTTAAA TGAAAGTAAG TAGCCGGGGT 60
GGCGGTCGGT CCGGTGTGCG GGTGGGGTGC CCCGCCGCTC CCCGGCCATC CGGGGCTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002257	Ailuropoda melanoleuca	98.14	0.00e+00	4761.00
IUUC-Apl-003284	Anas platyrhynchos	94.61	0.00e+00	4305.00
IUUC-Aca-004415	Anolis carolinensis	92.58	0.00e+00	4516.00
IUUC-Acl-008140	Aspergillus clavatus	28.62	4.00e-64	241.00
IUUC-Afl-008381	Aspergillus flavus	28.31	6.00e-64	240.00
IUUC-Afu-008857	Aspergillus fumigatus	26.86	1.00e-63	239.00
IUUC-Ani-009257	Aspergillus nidulans	28.87	2.00e-56	215.00
IUUC-Ang-009759	Aspergillus niger	27.72	1.00e-63	239.00
IUUC-Aor-009931	Aspergillus oryzae	28.31	7.00e-64	240.00
IUUC-Ate-010246	Aspergillus terreus	29.24	1.00e-52	203.00
IUUC-Ame-011219	Astyanax mexicanus	57.11	0.00e+00	1291.00
IUUC-Bgr-012195	Blumeria graminis	26.48	2.00e-64	242.00
IUUC-Bta-012989	Bos taurus	97.70	0.00e+00	4750.00
IUUC-Bci-013798	Botrytis cinerea	32.44	4.00e-58	221.00
IUUC-Cfa-021214	Canis familiaris	98.18	0.00e+00	4765.00
IUUC-Csa-023658	Chlorocebus sabaeus	98.23	0.00e+00	4769.00
IUUC-Cho-024971	Choloepus hoffmanni	75.06	0.00e+00	1286.00
IUUC-Cgl-026466	Colletotrichum gloeosporioides	28.46	5.00e-63	238.00
IUUC-Dre-027428	Danio rerio	90.30	0.00e+00	3079.00
IUUC-Dno-029690	Dasypus novemcinctus	97.22	0.00e+00	4604.00
IUUC-Dor-030817	Dipodomys ordii	93.65	0.00e+00	1483.00
IUUC-Dse-031423	Dothistroma septosporum	25.23	7.00e-36	147.00
IUUC-Dme-032102	Drosophila melanogaster	47.74	0.00e+00	707.00
IUUC-Ete-032552	Echinops telfairi	86.80	0.00e+00	1979.00
IUUC-Eca-033457	Equus caballus	98.46	0.00e+00	4487.00
IUUC-Eeu-035118	Erinaceus europaeus	94.27	0.00e+00	1113.00
IUUC-Fca-036213	Felis catus	94.72	0.00e+00	2986.00
IUUC-Fal-037643	Ficedula albicollis	93.77	0.00e+00	4536.00
IUUC-Fox-037971	Fusarium oxysporum	27.43	8.00e-63	236.00
IUUC-Fso-038108	Fusarium solani	27.26	1.00e-59	226.00
IUUC-Ggr-040075	Gaeumannomyces graminis	32.63	2.00e-62	235.00
IUUC-Gga-040511	Gallus gallus	93.20	0.00e+00	4543.00
IUUC-Gac-042024	Gasterosteus aculeatus	85.92	0.00e+00	3846.00
IUUC-Ggo-044924	Gorilla gorilla	93.94	0.00e+00	4237.00
IUUC-Hsa-046913	Homo sapiens	98.19	0.00e+00	4791.00
IUUC-Itr-048626	Ictidomys tridecemlineatus	98.15	0.00e+00	4762.00
IUUC-Lch-049675	Latimeria chalumnae	83.49	0.00e+00	3959.00
IUUC-Loc-052832	Lepisosteus oculatus	87.10	0.00e+00	4212.00
IUUC-Lma-053130	Leptosphaeria maculans	27.49	1.00e-60	229.00
IUUC-Laf-054169	Loxodonta africana	96.48	0.00e+00	4723.00
IUUC-Mcc-055847	Macaca mulatta	96.62	0.00e+00	4657.00
IUUC-Meu-056327	Macropus eugenii	82.88	0.00e+00	1272.00
IUUC-Mor-057152	Magnaporthe oryzae	35.14	1.00e-61	233.00
IUUC-Mpo-057310	Magnaporthe poae	31.03	2.00e-59	226.00
IUUC-Mmr-060780	Microcebus murinus	98.51	0.00e+00	4835.00
IUUC-Mdo-062308	Monodelphis domestica	91.81	0.00e+00	4183.00
IUUC-Mmu-063457	Mus musculus	95.72	0.00e+00	4708.00
IUUC-Mpu-066917	Mustela putorius furo	98.26	0.00e+00	4767.00
IUUC-Mlu-067696	Myotis lucifugus	98.14	0.00e+00	4754.00
IUUC-Nfi-068259	Neosartorya fischeri	27.21	3.00e-64	241.00
IUUC-Ncr-068911	Neurospora crassa	26.07	3.00e-59	224.00
IUUC-Nle-069586	Nomascus leucogenys	98.10	0.00e+00	4789.00
IUUC-Opr-070447	Ochotona princeps	87.83	0.00e+00	2063.00
IUUC-Ont-072396	Oreochromis niloticus	84.30	0.00e+00	3912.00
IUUC-Oan-073147	Ornithorhynchus anatinus	94.41	0.00e+00	4595.00
IUUC-Ocu-074324	Oryctolagus cuniculus	98.30	0.00e+00	4754.00
IUUC-Ola-086312	Oryzias latipes	81.69	0.00e+00	3732.00
IUUC-Oga-088878	Otolemur garnettii	98.18	0.00e+00	4768.00
IUUC-Oar-089919	Ovis aries	97.70	0.00e+00	4747.00
IUUC-Ptr-090713	Pan troglodytes	98.30	0.00e+00	4765.00
IUUC-Pan-091957	Papio anubis	99.09	0.00e+00	3051.00
IUUC-Psi-093240	Pelodiscus sinensis	93.44	0.00e+00	4511.00
IUUC-Pma-094469	Petromyzon marinus	77.73	0.00e+00	2758.00
IUUC-Pno-095059	Phaeosphaeria nodorum	29.76	5.00e-57	217.00
IUUC-Pfo-097159	Poecilia formosa	81.21	0.00e+00	3979.00
IUUC-Pab-098003	Pongo abelii	97.55	0.00e+00	4423.00
IUUC-Pca-100799	Procavia capensis	89.57	0.00e+00	1614.00
IUUC-Pva-103226	Pteropus vampyrus	93.96	0.00e+00	4507.00
IUUC-Pte-104235	Pyrenophora teres	26.97	2.00e-59	225.00
IUUC-Pyt-104803	Pyrenophora triticirepentis	27.42	3.00e-61	230.00
IUUC-Rno-105389	Rattus norvegicus	96.72	0.00e+00	3527.00
IUUC-Sha-106979	Sarcophilus harrisii	93.59	0.00e+00	4581.00
IUUC-Sar-113444	Sorex araneus	90.16	0.00e+00	4031.00
IUUC-Ssc-115815	Sus scrofa	97.28	0.00e+00	4748.00
IUUC-Tgu-117470	Taeniopygia guttata	93.86	0.00e+00	4262.00
IUUC-Tru-118543	Takifugu rubripes	85.32	0.00e+00	3831.00
IUUC-Tsy-119081	Tarsius syrichta	84.37	0.00e+00	2863.00
IUUC-Tni-120294	Tetraodon nigroviridis	81.71	5.00e-165	573.00
IUUC-Tre-122057	Trichoderma reesei	29.73	5.00e-63	237.00
IUUC-Tvi-122570	Trichoderma virens	35.89	4.00e-59	224.00
IUUC-Tme-127154	Tuber melanosporum	27.40	4.00e-59	223.00
IUUC-Tbe-127801	Tupaia belangeri	81.35	0.00e+00	1449.00
IUUC-Ttr-129262	Tursiops truncatus	94.60	0.00e+00	4535.00
IUUC-Vda-129686	Verticillium dahliae	27.91	7.00e-62	233.00
IUUC-Vpa-130484	Vicugna pacos	92.79	0.00e+00	4404.00
IUUC-Xtr-131769	Xenopus tropicalis	84.69	0.00e+00	4203.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence