iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-054867

UUCD1 version

UUC-MaM-00004

Ensembl Protein ID

ENSMMUP00000049941.1

UniProt Accession

G7NDK1; G7NDK1_MACMU

Genbank Protein ID

AFE79499.1; EHH22979.1

Protein Name

V(D)J recombination-activating protein 1

Genbank Nucleotide ID

JSUE03012424; CM001266

Gene Name

RAG1; EGK_06344

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000045691.1	ENSMMUT00000061942.1	ENSMMUP00000049941.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	97.99	0.00e+00	2066.00	IUUC-Hsa-045964
E3 activity/RING/RING	89.26	0.00e+00	1906.00	IUUC-Mmu-064297

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MASSFPPTLG LSSAPDEIQH PYIKFSEWKF KLFRVRSFEK TPEEAQREKK DSFEGKPSLE 60
QSPAVLDKAD GQKPVPNQPV LKAHPKFSKK FHDTGKARVK AIHQANLRHL CRICGNSFKT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATAAACAGC TCAGCAGCAT GTTCTGAGAA ACGAGAGCAA GGAGAGAGCA GAGAACACAC 60
TTTGCCTTCT CTTTGGTATT GAGTAATATC AATCAAGTTG CAGACATCTC AACACTTTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0233--DNA recombination
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR024627--RAG1
IPR019485--RAG1_Znf
IPR023336--RAG_nonamer-bd_dom
IPR013087--Znf_C2H2_type
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51487--NBD
PS51765--ZF_RAG1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12940--RAG1
PF00097--zf-C3HC4
PF10426--zf-RAG1

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0004519--F:endonuclease activity
GO:0043565--F:sequence-specific DNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0002250--P:adaptive immune response
GO:0010390--P:histone monoubiquitination
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070244--P:negative regulation of thymocyte apoptotic process
GO:0045582--P:positive regulation of T cell differentiation
GO:0002331--P:pre-B cell allelic exclusion
GO:0051865--P:protein autoubiquitination
GO:0033077--P:T cell differentiation in thymus
GO:0043029--P:T cell homeostasis
GO:0048538--P:thymus development
GO:0033151--P:V(D)J recombination

KEGG

mcc:697322

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001206	Ailuropoda melanoleuca	91.56	0.00e+00	1943.00
IUUC-Apl-003271	Anas platyrhynchos	76.64	0.00e+00	1652.00
IUUC-Aca-004400	Anolis carolinensis	73.93	0.00e+00	1621.00
IUUC-Ame-011295	Astyanax mexicanus	58.06	0.00e+00	1208.00
IUUC-Bta-012421	Bos taurus	91.27	0.00e+00	1932.00
IUUC-Cja-019891	Callithrix jacchus	95.78	0.00e+00	1992.00
IUUC-Cfa-020740	Canis familiaris	83.60	0.00e+00	1821.00
IUUC-Cpo-021800	Cavia porcellus	90.28	0.00e+00	1844.00
IUUC-Csa-024203	Chlorocebus sabaeus	98.51	0.00e+00	1848.00
IUUC-Dre-028416	Danio rerio	58.55	0.00e+00	1194.00
IUUC-Dno-029101	Dasypus novemcinctus	91.05	0.00e+00	1899.00
IUUC-Eca-033385	Equus caballus	92.71	0.00e+00	1951.00
IUUC-Fca-036545	Felis catus	91.37	0.00e+00	1949.00
IUUC-Fal-037208	Ficedula albicollis	75.67	0.00e+00	1656.00
IUUC-Gmo-039622	Gadus morhua	54.07	0.00e+00	1101.00
IUUC-Gga-041182	Gallus gallus	75.94	0.00e+00	1604.00
IUUC-Gac-041682	Gasterosteus aculeatus	57.28	0.00e+00	1198.00
IUUC-Ggo-044510	Gorilla gorilla	97.99	0.00e+00	2063.00
IUUC-Hsa-045964	Homo sapiens	97.99	0.00e+00	2063.00
IUUC-Itr-048862	Ictidomys tridecemlineatus	91.95	0.00e+00	1932.00
IUUC-Lch-050041	Latimeria chalumnae	70.27	0.00e+00	1477.00
IUUC-Loc-052464	Lepisosteus oculatus	63.46	0.00e+00	1359.00
IUUC-Laf-053544	Loxodonta africana	91.56	0.00e+00	1938.00
IUUC-Meu-055986	Macropus eugenii	83.23	0.00e+00	1607.00
IUUC-Mga-059262	Meleagris gallopavo	76.33	0.00e+00	1614.00
IUUC-Mdo-062686	Monodelphis domestica	81.76	0.00e+00	1777.00
IUUC-Mmu-064297	Mus musculus	89.26	0.00e+00	1939.00
IUUC-Mpu-066027	Mustela putorius furo	91.56	0.00e+00	1923.00
IUUC-Mlu-067885	Myotis lucifugus	92.62	0.00e+00	1962.00
IUUC-Nle-070073	Nomascus leucogenys	97.32	0.00e+00	2055.00
IUUC-Ont-071400	Oreochromis niloticus	60.65	0.00e+00	1264.00
IUUC-Oan-072920	Ornithorhynchus anatinus	94.67	0.00e+00	786.00
IUUC-Ocu-074616	Oryctolagus cuniculus	93.00	0.00e+00	1939.00
IUUC-Ola-086828	Oryzias latipes	59.94	0.00e+00	1226.00
IUUC-Oga-088675	Otolemur garnettii	94.46	4.00e-155	540.00
IUUC-Oar-090380	Ovis aries	90.80	0.00e+00	1944.00
IUUC-Ptr-090648	Pan troglodytes	98.08	0.00e+00	2065.00
IUUC-Pan-092036	Papio anubis	99.71	0.00e+00	2094.00
IUUC-Psi-093130	Pelodiscus sinensis	80.50	0.00e+00	1745.00
IUUC-Pfo-097273	Poecilia formosa	59.37	0.00e+00	1207.00
IUUC-Pca-100134	Procavia capensis	85.15	0.00e+00	1784.00
IUUC-Rno-105632	Rattus norvegicus	89.55	0.00e+00	1937.00
IUUC-Sha-107238	Sarcophilus harrisii	81.76	0.00e+00	1786.00
IUUC-Sar-113591	Sorex araneus	79.20	0.00e+00	1638.00
IUUC-Ssc-115720	Sus scrofa	91.28	0.00e+00	1915.00
IUUC-Tgu-117030	Taeniopygia guttata	75.44	0.00e+00	1632.00
IUUC-Tru-117669	Takifugu rubripes	57.99	0.00e+00	1151.00
IUUC-Tsy-119578	Tarsius syrichta	88.49	0.00e+00	1873.00
IUUC-Tni-120073	Tetraodon nigroviridis	58.62	0.00e+00	1187.00
IUUC-Tbe-128029	Tupaia belangeri	86.33	0.00e+00	960.00
IUUC-Ttr-128677	Tursiops truncatus	93.73	0.00e+00	809.00
IUUC-Vpa-130346	Vicugna pacos	95.03	0.00e+00	883.00
IUUC-Xtr-132442	Xenopus tropicalis	85.57	3.00e-100	357.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence