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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Rno-105198
Ensembl Protein ID ENSRNOP00000009621.2
UniProt Accession G3V6W5; G3V6W5_RAT
Genbank Protein ID EDL79011.1
Protein Name Interferon-induced with helicase C domain 1; Similar to HELICARD (Predicted)
Genbank Nucleotide ID AABR07052347
Gene Name Ifih1; RGD1560496_predicted; rCG_27124
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000006227.5 ENSRNOT00000009620.3 ENSRNOP00000009621.2
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
TRANSFACRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/CARD 2.40e-35 121.3 8 80
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/CARD
   S: 2    deeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL...vqkegWfrefl 73
           ++ +r l+s +++rv++ ++v++vld yl  fl++e ke+il+ + t gn +aaelLL+tL    + +gW++ f+
   Q: 8    EDSFRNLISIFRPRVKMNIQVEPVLD-YLV-FLPAETKEQILRKVTTCGNTSAAELLLSTLeqgQWPLGWTQMFV 80
           6889**********************.***.****************************************9885 PP
   
Organism Rattus norvegicus
Protein Sequence
(Fasta)
MSTVCSAEDS FRNLISIFRP RVKMNIQVEP VLDYLVFLPA ETKEQILRKV TTCGNTSAAE 60
LLLSTLEQGQ WPLGWTQMFV EALEHSGNPL AARYVKPSLT DLPSPSSETA HDECLHLLNL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105198|UBD,CARD|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGGCCGGCGG TGGCAGTGAG AGTAGTCCGG GGTCTATGAC CACCTGCTGC AGCGCATTCC 60
TGGCTCGTCT GCCACCTTCC GGGTGCCACC GATCAATCCG GTGCTCAGAG GCTACCCGGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105198|UBD,CARD|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR
PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR
Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD
SMART

SM00487--DEXDc
SM00490--HELICc
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation
KEGG rno:499801
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001336 Ailuropoda melanoleuca 76.41 0.00e+00 1499.00
IUUC-Apl-003900 Anas platyrhynchos 59.65 0.00e+00 1162.00
IUUC-Aca-005329 Anolis carolinensis 58.16 0.00e+00 1024.00
IUUC-Ame-011305 Astyanax mexicanus 53.36 0.00e+00 758.00
IUUC-Bta-012361 Bos taurus 77.52 0.00e+00 1478.00
IUUC-Cel-018230 Caenorhabditis elegans 27.24 7.00e-61 229.00
IUUC-Cja-018760 Callithrix jacchus 78.19 0.00e+00 1483.00
IUUC-Cfa-020321 Canis familiaris 76.39 0.00e+00 1451.00
IUUC-Cpo-022450 Cavia porcellus 72.98 0.00e+00 1448.00
IUUC-Cre-022916 Chlamydomonas reinhardtii 33.33 3.00e-12 68.20
IUUC-Csa-024194 Chlorocebus sabaeus 80.23 0.00e+00 1491.00
IUUC-Cho-024364 Choloepus hoffmanni 69.16 0.00e+00 963.00
IUUC-Cin-025792 Ciona intestinalis 29.49 2.00e-67 249.00
IUUC-Cgl-026385 Colletotrichum gloeosporioides 30.60 2.00e-14 75.90
IUUC-Dre-028305 Danio rerio 46.15 0.00e+00 755.00
IUUC-Dno-029831 Dasypus novemcinctus 77.60 0.00e+00 1513.00
IUUC-Dor-030410 Dipodomys ordii 73.53 0.00e+00 1179.00
IUUC-Ete-032950 Echinops telfairi 71.33 8.00e-178 617.00
IUUC-Eca-034279 Equus caballus 77.63 0.00e+00 1479.00
IUUC-Eeu-034678 Erinaceus europaeus 73.74 0.00e+00 1467.00
IUUC-Fca-035618 Felis catus 80.14 0.00e+00 918.00
IUUC-Fal-037106 Ficedula albicollis 67.17 0.00e+00 959.00
IUUC-Fso-038398 Fusarium solani 31.68 6.00e-14 73.90
IUUC-Gmo-038598 Gadus morhua 47.84 0.00e+00 659.00
IUUC-Gga-040467 Gallus gallus 60.06 0.00e+00 1157.00
IUUC-Gac-042316 Gasterosteus aculeatus 46.80 0.00e+00 831.00
IUUC-Ggo-045461 Gorilla gorilla 79.65 0.00e+00 1477.00
IUUC-Hsa-045771 Homo sapiens 79.45 0.00e+00 1473.00
IUUC-Itr-048762 Ictidomys tridecemlineatus 77.90 0.00e+00 1491.00
IUUC-Lch-049913 Latimeria chalumnae 64.98 0.00e+00 911.00
IUUC-Loc-052768 Lepisosteus oculatus 52.22 0.00e+00 969.00
IUUC-Laf-053933 Loxodonta africana 77.28 0.00e+00 1471.00
IUUC-Mcc-054695 Macaca mulatta 80.33 0.00e+00 1494.00
IUUC-Meu-056829 Macropus eugenii 70.47 0.00e+00 1073.00
IUUC-Mga-059205 Meleagris gallopavo 59.57 0.00e+00 1143.00
IUUC-Mvi-060497 Microbotryum violaceum 33.96 4.00e-18 87.80
IUUC-Mmr-060703 Microcebus murinus 78.29 0.00e+00 1462.00
IUUC-Mdo-063079 Monodelphis domestica 68.38 0.00e+00 1374.00
IUUC-Mmu-064066 Mus musculus 93.18 0.00e+00 1908.00
IUUC-Mpu-066261 Mustela putorius furo 75.88 0.00e+00 1446.00
IUUC-Mlu-068196 Myotis lucifugus 76.85 0.00e+00 1462.00
IUUC-Nfi-068405 Neosartorya fischeri 25.12 3.00e-25 111.00
IUUC-Nle-069479 Nomascus leucogenys 77.51 0.00e+00 1446.00
IUUC-Opr-070717 Ochotona princeps 69.43 0.00e+00 1059.00
IUUC-Ont-071702 Oreochromis niloticus 46.26 0.00e+00 850.00
IUUC-Oan-073639 Ornithorhynchus anatinus 62.90 0.00e+00 1138.00
IUUC-Ocu-074521 Oryctolagus cuniculus 77.09 0.00e+00 1497.00
IUUC-Ola-086351 Oryzias latipes 45.07 0.00e+00 801.00
IUUC-Oga-088539 Otolemur garnettii 76.24 0.00e+00 1466.00
IUUC-Oar-090186 Ovis aries 77.20 0.00e+00 1439.00
IUUC-Ptr-090575 Pan troglodytes 77.60 0.00e+00 1447.00
IUUC-Pan-092371 Papio anubis 80.43 0.00e+00 1494.00
IUUC-Psi-093072 Pelodiscus sinensis 61.12 0.00e+00 1193.00
IUUC-Pma-094345 Petromyzon marinus 42.59 2.00e-93 336.00
IUUC-Pfo-096401 Poecilia formosa 51.25 0.00e+00 665.00
IUUC-Pab-097623 Pongo abelii 78.48 0.00e+00 1472.00
IUUC-Pca-100993 Procavia capensis 69.90 0.00e+00 1186.00
IUUC-Pva-102227 Pteropus vampyrus 72.76 0.00e+00 1355.00
IUUC-Pgr-103529 Puccinia graminis 39.34 3.00e-17 84.70
IUUC-Sha-107622 Sarcophilus harrisii 69.78 0.00e+00 1369.00
IUUC-Sar-113625 Sorex araneus 65.59 0.00e+00 677.00
IUUC-Tgu-117486 Taeniopygia guttata 58.67 0.00e+00 1098.00
IUUC-Tru-118445 Takifugu rubripes 44.57 0.00e+00 797.00
IUUC-Tsy-119512 Tarsius syrichta 77.12 0.00e+00 1417.00
IUUC-Tni-120711 Tetraodon nigroviridis 44.12 0.00e+00 818.00
IUUC-Tre-122194 Trichoderma reesei 35.00 5.00e-13 70.90
IUUC-Tbe-127644 Tupaia belangeri 70.40 0.00e+00 1312.00
IUUC-Ttr-128989 Tursiops truncatus 74.00 0.00e+00 1455.00
IUUC-Vpa-130587 Vicugna pacos 74.09 0.00e+00 1189.00
IUUC-Xtr-132127 Xenopus tropicalis 52.20 0.00e+00 977.00
Created Date 25-Jun-2017

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