iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000021023.3	ENSMMUT00000059101.1	ENSMMUP00000041429.1
ENSMMUG00000021023.3	ENSMMUT00000064696.1	ENSMMUP00000043954.1
ENSMMUG00000021023.3	ENSMMUT00000078836.1	ENSMMUP00000055807.1
ENSMMUG00000021023.3	ENSMMUT00000029563.3	ENSMMUP00000027664.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	8.60e-34	117.4	44	137

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 41   pYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsvesvllsiqsllaepnpesplneeaaellkkn 129
           +Ye+  +kl++efp+ YP+++P+vkflt+++hPnv+++G++Cl+ilk  +kWs+ ++v+++llsiqsll epn++spln++aael+k+ 
   Q: 44   VYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILK--DKWSALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWKNP 130
           7*********************************************9..***********************************99765 PP
   S: 130  reeykkkv 137
             ++kk +
   Q: 131  T-AFKKYL 137
           5.488765 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MASQNRDPAA TSVTAARKGA EPSGGAARGP VGKRLQQELM TLMVYEDLRY KLSLEFPSGY 60
PYNAPTVKFL TPCYHPNVDT QGNICLDILK DKWSALYDVR TILLSIQSLL GEPNIDSPLN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTCCC AAAACCGCGA CCCGGCAGCC ACTAGCGTCA CCGCCGCCCG TAAAGGAGCC 60
GAGCCGAGCG GGGGCGCCGC CCGGGGTCCC GTGGGCAAAA GGTGGGTGAC GCGGCGTACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Mga-059929	Meleagris gallopavo	87.76	3.00e-49	186.00
IUUC-Oan-073728	Ornithorhynchus anatinus	76.67	6.00e-39	151.00
IUUC-Obr-076757	Oryza brachyantha	70.65	2.00e-36	143.00
IUUC-Psi-093206	Pelodiscus sinensis	92.45	2.00e-56	209.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence