iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-047868

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01012808

Gene Name

UBE2D4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000002630.2	ENSSTOT00000002625.2	ENSSTOP00000002348.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.10e-54	182.5	5	137
UBD/UBC-like/UBD_UBC	5.20e-77	256.6	5	136

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel++l++dpp+++sa+pv + dl++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+tki+hPn+++nG++Cl+il+  
   Q: 5    RIQKELTDLQRDPPAQCSAGPVGD-DLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILR-- 90
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsves.vllsiqsllaepnpesplneeaaellkknreeykk 135
           ++Wspal+v++ +llsi+sll++pnp++pl  e+a+++k++re+y +
   Q: 91   SQWSPALTVSKgILLSICSLLCDPNPDDPLVPEIAHTYKADREKYAS 137
           *********8769********************************75 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqw 89
           ri+kel dl+rd++aq+sa++v+ddlf+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+tkiyhpninsngsicldilrsqw
   Q: 5    RIQKELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILRSQW 93
           8**************************************************************************************** PP
   S: 90   saaltlsk.vllslcslladaepddplvaeiariyktdkekyk 131
           s+alt+sk +lls+csll+d++pddplv+eia+ yk+d+eky 
   Q: 94   SPALTVSKgILLSICSLLCDPNPDDPLVPEIAHTYKADREKYA 136
           ******98689******************************96 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MALKRIQKEL TDLQRDPPAQ CSAGPVGDDL FHWQATIMGP NDSPYQGGVF FLTIHFPTDY 60
PFKPPKVAFT TKIYHPNINS NGSICLDILR SQWSPALTVS KGILLSICSL LCDPNPDDPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCACTGA AGCGGATCCA GAAGGTAAGG GGCCTCCCCA CCTTTCGACC TGGGCGTCTA 60
GAGCGTCTAA ATGAGGGCCG GATGCAACTG CCACGAAGCG ACCGATGACT GGCGCGGCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0070979--P:protein K11-linked ubiquitination
GO:0044314--P:protein K27-linked ubiquitination
GO:0035519--P:protein K29-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0085020--P:protein K6-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-012632	Bos taurus	97.10	3.00e-76	276.00
IUUC-Gmo-038604	Gadus morhua	96.27	6.00e-74	268.00
IUUC-Gac-042577	Gasterosteus aculeatus	94.74	2.00e-72	263.00
IUUC-Oga-089011	Otolemur garnettii	95.49	4.00e-72	263.00
IUUC-Oar-090224	Ovis aries	92.75	8.00e-73	265.00
IUUC-Tru-118588	Takifugu rubripes	94.20	1.00e-74	271.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence