iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050682

Ensembl Protein ID

ENSLACP00000010974.1

UniProt Accession

H3AMV3; H3AMV3_LATCH

Genbank Protein ID

ENSLACP00000010974

Protein Name

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; WD repeat-containing protein 4

Genbank Nucleotide ID

AFYH01165367

Gene Name

WDR4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000009655.1	ENSLACT00000011056.1	ENSLACP00000010974.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.90e-08	33.0	188	225

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvl 35
           gH + v+ +    +  +ll+sGs+Dgt+++W++++g+ 
   Q: 188  GHREFVSTILVlpNHpNLLLSGSGDGTLRLWEYKSGRE 225
           56666777643664479***************999975 PP

Organism

Latimeria chalumnae

Functional Description
(View)

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Protein Sequence
(Fasta)

SMAALRFSRD WLVISSGSKF LAHSCGDKSD NQKPFVYDCS TAVKEPAPEE KGNDGHVNSK 60
GSDRILAFTF SPSGKYFALI DDSKRLVLFR TEPSWECLSV RCLVRRCTSL AITHAEGQIL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACAGCATGG CGGCCCTGCG CTTCTCCCGG GATTGGCTGG TAATCAGCAG CGGCAGCAAG 60
TTTCTGGCGC ACAGTTGCGG AGATAAAAGG TTAGAGGTGG CAGAAAGGAA AAGAAAGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0819--tRNA processing
KW-0853--WD repeat

Interpro

IPR028884--Trm82
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0036265--P:RNA (guanine-N7)-methylation
GO:0030488--P:tRNA methylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000556	Aegilops tauschii	26.69	8.00e-09	54.70
IUUC-Atr-002431	Amborella trichopoda	36.36	1.00e-11	61.60
IUUC-Apl-003975	Anas platyrhynchos	58.36	1.00e-116	412.00
IUUC-Aca-005170	Anolis carolinensis	53.96	5.00e-93	334.00
IUUC-Aly-005769	Arabidopsis lyrata	34.55	1.00e-27	117.00
IUUC-Ath-006733	Arabidopsis thaliana	34.27	2.00e-26	113.00
IUUC-Acl-008151	Aspergillus clavatus	44.33	1.00e-13	71.20
IUUC-Afl-008518	Aspergillus flavus	29.83	4.00e-15	75.50
IUUC-Afu-009102	Aspergillus fumigatus	28.62	1.00e-15	77.80
IUUC-Ani-009442	Aspergillus nidulans	28.11	6.00e-14	72.00
IUUC-Aor-010133	Aspergillus oryzae	26.97	1.00e-18	87.80
IUUC-Ate-010465	Aspergillus terreus	28.75	4.00e-16	79.30
IUUC-Ame-010613	Astyanax mexicanus	44.76	4.00e-91	328.00
IUUC-Bgr-012067	Blumeria graminis	35.44	2.00e-18	87.00
IUUC-Bta-012788	Bos taurus	54.40	9.00e-111	393.00
IUUC-Bdi-014458	Brachypodium distachyon	31.58	2.00e-16	80.10
IUUC-Bol-016398	Brassica oleracea	38.46	1.00e-29	124.00
IUUC-Bra-016644	Brassica rapa	36.53	1.00e-27	118.00
IUUC-Cpo-021963	Cavia porcellus	52.16	7.00e-100	357.00
IUUC-Csa-024148	Chlorocebus sabaeus	51.92	1.00e-86	313.00
IUUC-Cne-026834	Cryptococcus neoformans	34.72	3.00e-18	86.70
IUUC-Dre-028427	Danio rerio	48.18	2.00e-97	348.00
IUUC-Dno-028881	Dasypus novemcinctus	48.58	2.00e-96	345.00
IUUC-Dor-030522	Dipodomys ordii	51.52	4.00e-102	364.00
IUUC-Dme-032136	Drosophila melanogaster	31.14	1.00e-27	117.00
IUUC-Fca-035833	Felis catus	54.47	4.00e-106	377.00
IUUC-Fal-037497	Ficedula albicollis	58.88	6.00e-118	417.00
IUUC-Gga-040547	Gallus gallus	54.68	9.00e-110	390.00
IUUC-Gac-041761	Gasterosteus aculeatus	45.03	5.00e-82	297.00
IUUC-Gma-043722	Glycine max	32.49	2.00e-23	103.00
IUUC-Ggo-045340	Gorilla gorilla	51.10	4.00e-93	334.00
IUUC-Hsa-046403	Homo sapiens	51.37	2.00e-93	336.00
IUUC-Hvu-047643	Hordeum vulgare	31.62	4.00e-18	85.90
IUUC-Itr-048103	Ictidomys tridecemlineatus	53.87	4.00e-109	388.00
IUUC-Kpa-049283	Komagataella pastoris	26.61	4.00e-21	95.50
IUUC-Lpe-050712	Leersia perrieri	33.47	1.00e-26	114.00
IUUC-Loc-052599	Lepisosteus oculatus	54.07	2.00e-120	425.00
IUUC-Laf-054390	Loxodonta africana	52.80	1.00e-109	389.00
IUUC-Mcc-054747	Macaca mulatta	51.65	1.00e-90	326.00
IUUC-Mtr-058600	Medicago truncatula	33.33	4.00e-28	119.00
IUUC-Mla-059129	Melampsora laricipopulina	28.92	1.00e-14	73.60
IUUC-Mga-059876	Meleagris gallopavo	54.97	9.00e-111	393.00
IUUC-Mvi-060359	Microbotryum violaceum	32.08	6.00e-15	75.90
IUUC-Mmr-061518	Microcebus murinus	50.67	1.00e-99	356.00
IUUC-Mac-065417	Musa acuminata	30.85	6.00e-26	111.00
IUUC-Nfi-068402	Neosartorya fischeri	28.62	2.00e-15	77.40
IUUC-Nle-069914	Nomascus leucogenys	50.27	2.00e-85	309.00
IUUC-Ont-071555	Oreochromis niloticus	44.70	5.00e-86	311.00
IUUC-Oan-072951	Ornithorhynchus anatinus	53.70	4.00e-112	397.00
IUUC-Ocu-074679	Oryctolagus cuniculus	53.57	9.00e-100	357.00
IUUC-Oba-075355	Oryza barthii	28.06	3.00e-14	73.20
IUUC-Obr-076769	Oryza brachyantha	32.36	1.00e-27	117.00
IUUC-Ogl-077168	Oryza glaberrima	31.41	1.00e-27	117.00
IUUC-Ogu-078275	Oryza glumaepatula	27.38	5.00e-14	72.40
IUUC-Oin-079207	Oryza indica	31.41	1.00e-27	117.00
IUUC-Oni-082437	Oryza nivara	26.35	1.00e-13	70.90
IUUC-Opu-084031	Oryza punctata	31.21	8.00e-26	111.00
IUUC-Oru-084380	Oryza rufipogon	28.06	7.00e-14	72.00
IUUC-Osa-085327	Oryza sativa	31.41	3.00e-27	115.00
IUUC-Ola-086716	Oryzias latipes	41.04	3.00e-76	278.00
IUUC-Olu-087708	Ostreococcus lucimarinus	29.27	2.00e-19	90.10
IUUC-Oar-090239	Ovis aries	54.62	2.00e-109	388.00
IUUC-Ptr-090851	Pan troglodytes	51.10	2.00e-93	335.00
IUUC-Pan-092558	Papio anubis	51.91	1.00e-85	309.00
IUUC-Psi-093792	Pelodiscus sinensis	53.94	9.00e-118	416.00
IUUC-Ppa-095757	Physcomitrella patens	37.87	4.00e-21	95.50
IUUC-Pfo-096465	Poecilia formosa	42.64	2.00e-83	302.00
IUUC-Pab-097722	Pongo abelii	51.73	1.00e-94	340.00
IUUC-Pop-098979	Populus trichocarpa	34.84	2.00e-25	110.00
IUUC-Pca-100753	Procavia capensis	52.40	6.00e-73	267.00
IUUC-Ppe-101515	Prunus persica	31.76	1.00e-22	100.00
IUUC-Sja-107780	Schizosaccharomyces japonicus	27.97	4.00e-15	75.90
IUUC-Spo-108251	Schizosaccharomyces pombe	27.09	2.00e-12	67.00
IUUC-Smo-108938	Selaginella moellendorffii	35.57	8.00e-22	98.20
IUUC-Sit-110020	Setaria italica	29.72	1.00e-23	103.00
IUUC-Sly-111543	Solanum lycopersicum	32.37	1.00e-25	110.00
IUUC-Stu-111925	Solanum tuberosum	32.37	4.00e-25	108.00
IUUC-Sbi-114061	Sorghum bicolor	31.18	9.00e-25	107.00
IUUC-Tgu-117321	Taeniopygia guttata	57.68	4.00e-109	387.00
IUUC-Tru-118454	Takifugu rubripes	44.42	1.00e-86	312.00
IUUC-Tni-119894	Tetraodon nigroviridis	44.02	7.00e-76	277.00
IUUC-Tca-121746	Theobroma cacao	33.33	2.00e-25	109.00
IUUC-Tae-124459	Triticum aestivum	30.63	7.00e-19	88.20
IUUC-Tur-126254	Triticum urartu	29.70	4.00e-11	62.40
IUUC-Tbe-127683	Tupaia belangeri	37.17	1.00e-32	133.00
IUUC-Ttr-129056	Tursiops truncatus	52.28	1.00e-99	356.00
IUUC-Vvi-131428	Vitis vinifera	32.92	2.00e-26	113.00
IUUC-Xma-133605	Xiphophorus maculatus	41.88	7.00e-81	293.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence