iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062357

Ensembl Protein ID

ENSMODP00000022570.2

UniProt Accession

F7FFD6; F7FFD6_MONDO

Protein Name

Inhibitor of growth protein

Gene Name

ING4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000018103.3	ENSMODT00000022964.3	ENSMODP00000022570.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	7.90e-10	38.9	197	244

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C+ ewfH+aC++l+   ++p+ + w+Cp+C++
   Q: 197  TYC-LCHQVSYGE--MIGCDNpdCSiEWFHFACVGLT---TKPRGK-WFCPRCSQ 244
           69*.*******99..********999***********...899996.******97 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAAGMYLEHY LDSIENLPFE LQRNFQLMRD LDQRTEDLKA EIDKLATEYM SSARSLNSEE 60
KLALLKQIQE AYGKCKEFGD DKVQLAMQTY EMVDKHIRRL DTDLARFEAD LKEKQIESSD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCGG GAATGTATTT GGAGCATTAT CTGGACAGTA AGAGGTTGCG GGTGTTGGGT 60
CGGCTGCCTT AGCGCGGGTG CAGGGCCAAG CCGAGATGGG ACATGCGCAC ATCGGTGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028647--ING4
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0000123--C:histone acetyltransferase complex
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0007050--P:cell cycle arrest
GO:0006978--P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0006260--P:DNA replication
GO:0043966--P:histone H3 acetylation
GO:0043983--P:histone H4-K12 acetylation
GO:0043981--P:histone H4-K5 acetylation
GO:0043982--P:histone H4-K8 acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:0045926--P:negative regulation of growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0043065--P:positive regulation of apoptotic process

KEGG

mdo:100013433

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001338	Ailuropoda melanoleuca	97.99	7.00e-126	442.00
IUUC-Apl-004097	Anas platyrhynchos	92.34	1.00e-117	415.00
IUUC-Aca-004593	Anolis carolinensis	95.58	3.00e-123	434.00
IUUC-Ame-011133	Astyanax mexicanus	79.28	2.00e-115	407.00
IUUC-Bta-012699	Bos taurus	96.79	1.00e-125	441.00
IUUC-Bdi-014504	Brachypodium distachyon	36.25	6.00e-39	154.00
IUUC-Cja-019988	Callithrix jacchus	98.39	6.00e-120	422.00
IUUC-Cfa-021282	Canis familiaris	98.39	6.00e-120	422.00
IUUC-Cpo-022011	Cavia porcellus	98.39	9.00e-130	455.00
IUUC-Cre-022920	Chlamydomonas reinhardtii	31.23	9.00e-29	120.00
IUUC-Csa-023203	Chlorocebus sabaeus	98.39	6.00e-120	422.00
IUUC-Dre-028264	Danio rerio	78.88	9.00e-114	402.00
IUUC-Dno-029766	Dasypus novemcinctus	95.56	2.00e-113	400.00
IUUC-Dor-031136	Dipodomys ordii	83.90	3.00e-98	350.00
IUUC-Dme-032200	Drosophila melanogaster	74.19	2.00e-40	159.00
IUUC-Eca-033565	Equus caballus	98.39	1.00e-129	455.00
IUUC-Eeu-034948	Erinaceus europaeus	78.95	2.00e-99	354.00
IUUC-Fca-036368	Felis catus	98.80	2.00e-120	424.00
IUUC-Fal-037120	Ficedula albicollis	91.94	4.00e-116	410.00
IUUC-Gmo-038982	Gadus morhua	80.40	1.00e-114	405.00
IUUC-Gga-040771	Gallus gallus	95.58	3.00e-123	434.00
IUUC-Gac-042184	Gasterosteus aculeatus	79.67	6.00e-111	393.00
IUUC-Gma-044339	Glycine max	29.76	3.00e-34	138.00
IUUC-Ggo-045559	Gorilla gorilla	98.39	6.00e-120	422.00
IUUC-Hsa-046852	Homo sapiens	98.39	6.00e-120	422.00
IUUC-Hvu-047046	Hordeum vulgare	35.71	5.00e-38	150.00
IUUC-Itr-047978	Ictidomys tridecemlineatus	97.99	3.00e-129	454.00
IUUC-Kpa-049229	Komagataella pastoris	59.18	1.00e-16	79.30
IUUC-Laf-054057	Loxodonta africana	98.80	2.00e-120	424.00
IUUC-Mcc-055212	Macaca mulatta	92.43	1.00e-114	405.00
IUUC-Meu-056511	Macropus eugenii	100.00	1.00e-122	431.00
IUUC-Mtr-058288	Medicago truncatula	32.22	9.00e-33	133.00
IUUC-Mga-059967	Meleagris gallopavo	93.12	4.00e-117	413.00
IUUC-Mmr-060843	Microcebus murinus	96.79	7.00e-126	442.00
IUUC-Mmu-064093	Mus musculus	98.39	9.00e-130	455.00
IUUC-Mpu-066923	Mustela putorius furo	87.15	3.00e-97	347.00
IUUC-Mlu-067754	Myotis lucifugus	90.87	5.00e-118	416.00
IUUC-Nle-069062	Nomascus leucogenys	98.39	6.00e-120	422.00
IUUC-Opr-070207	Ochotona princeps	91.53	8.00e-111	392.00
IUUC-Ont-072446	Oreochromis niloticus	80.80	2.00e-113	401.00
IUUC-Ocu-074235	Oryctolagus cuniculus	98.39	6.00e-120	422.00
IUUC-Ogl-077118	Oryza glaberrima	33.73	2.00e-36	145.00
IUUC-Ome-081291	Oryza meridionalis	33.73	7.00e-37	147.00
IUUC-Opu-084171	Oryza punctata	34.69	7.00e-36	144.00
IUUC-Osa-085563	Oryza sativa	33.73	7.00e-37	147.00
IUUC-Ola-086429	Oryzias latipes	76.00	1.00e-104	372.00
IUUC-Olu-087851	Ostreococcus lucimarinus	33.95	5.00e-20	90.90
IUUC-Oga-089123	Otolemur garnettii	98.80	2.00e-120	424.00
IUUC-Oar-089524	Ovis aries	96.79	1.00e-125	441.00
IUUC-Ptr-090908	Pan troglodytes	97.99	3.00e-119	421.00
IUUC-Pan-092837	Papio anubis	97.59	2.00e-125	441.00
IUUC-Psi-093828	Pelodiscus sinensis	95.28	8.00e-113	399.00
IUUC-Pma-094144	Petromyzon marinus	53.75	6.00e-26	109.00
IUUC-Ppa-096009	Physcomitrella patens	34.77	2.00e-34	139.00
IUUC-Pfo-096617	Poecilia formosa	80.40	2.00e-113	400.00
IUUC-Pab-097978	Pongo abelii	97.88	2.00e-109	387.00
IUUC-Pop-099415	Populus trichocarpa	73.68	2.00e-26	112.00
IUUC-Pca-100475	Procavia capensis	66.67	5.00e-86	310.00
IUUC-Ppe-101441	Prunus persica	32.94	5.00e-37	147.00
IUUC-Pva-102325	Pteropus vampyrus	98.39	1.00e-129	455.00
IUUC-Rno-105178	Rattus norvegicus	96.79	3.00e-135	473.00
IUUC-Sha-106773	Sarcophilus harrisii	100.00	2.00e-131	461.00
IUUC-Sit-109827	Setaria italica	34.26	3.00e-36	145.00
IUUC-Sly-111750	Solanum lycopersicum	32.94	3.00e-36	144.00
IUUC-Stu-112250	Solanum tuberosum	32.94	3.00e-36	144.00
IUUC-Sbi-114826	Sorghum bicolor	35.46	4.00e-37	147.00
IUUC-Sre-115124	Sporisorium reilianum	58.21	3.00e-22	100.00
IUUC-Ssc-115797	Sus scrofa	91.87	2.00e-104	371.00
IUUC-Tgu-117270	Taeniopygia guttata	95.58	3.00e-123	434.00
IUUC-Tru-118253	Takifugu rubripes	79.68	1.00e-113	402.00
IUUC-Tca-121597	Theobroma cacao	69.84	3.00e-28	118.00
IUUC-Tae-123043	Triticum aestivum	34.75	2.00e-37	148.00
IUUC-Tbe-127558	Tupaia belangeri	97.99	7.00e-126	442.00
IUUC-Ttr-128300	Tursiops truncatus	99.09	4.00e-65	240.00
IUUC-Uma-129581	Ustilago maydis	57.63	4.00e-21	96.70

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence