iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tre-122130

Ensembl Protein ID

EGR46449

UniProt Accession

G0RR23; G0RR23_HYPJQ

Genbank Protein ID

EGR46449.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

GL985073

Gene Name

TRIREDRAFT_80400

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIREDRAFT_80400	EGR46449	EGR46449

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	2.40e-60	203.5	4	275

Active Site

Position(s)	Description	Evidence
91	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
169	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 7    ewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCatyAllsv 107
           +w ++esd+g+ft l+e++gvk++ q+eel  Ldp  l  + +p++g+++lFk+  +   +  s   ++   v d d+ + iffa q+i+N+Cat+Allsv
   Q: 4    GWNTIESDAGVFTSLIENLGVKNV-QFEELLTLDPSELLAL-QPLYGVIFLFKYPTDGPYASASG-PQD--GVFDHDAAERIFFAAQTIQNACATQALLSV 99
           8***********************.**********999888.9**********988766555333.334..89**************************** PP
   S: 108  llncedkl.ldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyeldglkpfPldlgkkk 207
           lln + +  +d+G++++ ++++t    pe +++al+n++ ++ +hn +ar+ ++  ++ + ++     +++fhf++y++i+g lyeldgl+p+P+ +g+++
   Q: 100  LLNKDGEDgVDIGPQMKDFRDFTMVLPPEFRGEALSNSDLIREVHNGFARSSPFADETARHGEP---SEDVFHFIAYTPIDGTLYELDGLQPAPISHGPCT 197
           ****999999********************************************9998887775...899******************************* PP
   S: 208  eteelkdklkvvraflerikllesdeirfnllaivadrrviktlrlnvlkidkeLlkLlkdieseeekieaqlddekekrkkfkiddirRtenydeficif 308
            +e   + + v++    ri  +++ eirfnlla++ d r+                       + e   e+ l+ e+ kr  +  ++  R++n+++f  + 
   Q: 198  PDEFPIKVVDVLQ---RRIARYDEAEIRFNLLAMCRDLRIR----------------------AREFGDEELLERENRKRSDWAFENALRRHNFVGFAGEV 273
           9999988888887...9********************8873......................33444455566666666666666666666666666555 PP
   S: 309  ik 310
           +k
   Q: 274  LK 275
           55 PP

Organism

Trichoderma reesei

Protein Sequence
(Fasta)

MSGGWNTIES DAGVFTSLIE NLGVKNVQFE ELLTLDPSEL LALQPLYGVI FLFKYPTDGP 60
YASASGPQDG VFDHDAAERI FFAAQTIQNA CATQALLSVL LNKDGEDGVD IGPQMKDFRD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGTGGTG GTTGGAACAC GAGTAAGCCA TGGCCTCGGC AATTCGACCT GCAGCTTCTC 60
GGAAACTGAC GATATCTTCC TTCTTCCTCC TGCAGTCGAG TCCGATGCGG TATGTCCATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0034399--C:nuclear periphery
GO:0031595--C:nuclear proteasome complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

tre:TRIREDRAFT_80400

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	38.04	9.00e-57	211.00
IUUC-Aml-001866	Ailuropoda melanoleuca	39.10	1.00e-57	214.00
IUUC-Atr-002966	Amborella trichopoda	36.80	3.00e-50	191.00
IUUC-Apl-003306	Anas platyrhynchos	35.54	8.00e-50	189.00
IUUC-Aca-004763	Anolis carolinensis	39.10	2.00e-57	214.00
IUUC-Aly-005581	Arabidopsis lyrata	39.63	1.00e-53	201.00
IUUC-Ath-007283	Arabidopsis thaliana	39.94	8.00e-56	208.00
IUUC-Ago-007999	Ashbya gossypii	39.32	4.00e-44	169.00
IUUC-Acl-008231	Aspergillus clavatus	61.04	3.00e-95	339.00
IUUC-Afl-008557	Aspergillus flavus	62.27	5.00e-98	348.00
IUUC-Afu-008988	Aspergillus fumigatus	60.94	4.00e-95	339.00
IUUC-Ani-009420	Aspergillus nidulans	58.42	2.00e-98	350.00
IUUC-Ang-009859	Aspergillus niger	58.62	2.00e-89	320.00
IUUC-Aor-010145	Aspergillus oryzae	62.27	5.00e-98	348.00
IUUC-Ate-010347	Aspergillus terreus	58.31	1.00e-93	334.00
IUUC-Ame-010791	Astyanax mexicanus	38.71	1.00e-56	211.00
IUUC-Bgr-012298	Blumeria graminis	62.00	1.00e-102	363.00
IUUC-Bta-013251	Bos taurus	38.59	3.00e-57	213.00
IUUC-Bci-013786	Botrytis cinerea	65.12	7.00e-115	405.00
IUUC-Bdi-014132	Brachypodium distachyon	37.42	4.00e-55	206.00
IUUC-Bol-015611	Brassica oleracea	40.00	2.00e-56	211.00
IUUC-Bra-017769	Brassica rapa	41.23	6.00e-56	209.00
IUUC-Cel-018604	Caenorhabditis elegans	36.86	2.00e-47	180.00
IUUC-Cja-019768	Callithrix jacchus	35.59	4.00e-52	196.00
IUUC-Cfa-020207	Canis familiaris	39.10	1.00e-57	214.00
IUUC-Cpo-021925	Cavia porcellus	37.70	9.00e-53	198.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	46.88	7.00e-53	199.00
IUUC-Csa-023958	Chlorocebus sabaeus	38.59	3.00e-57	213.00
IUUC-Cho-024928	Choloepus hoffmanni	45.57	5.00e-12	63.20
IUUC-Cin-025771	Ciona intestinalis	36.93	9.00e-53	198.00
IUUC-Csv-026149	Ciona savignyi	36.31	2.00e-51	193.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	64.38	2.00e-108	383.00
IUUC-Cne-026955	Cryptococcus neoformans	34.57	2.00e-45	174.00
IUUC-Cme-027104	Cyanidioschyzon merolae	37.42	7.00e-47	179.00
IUUC-Dre-027409	Danio rerio	39.03	9.00e-57	211.00
IUUC-Dno-028921	Dasypus novemcinctus	39.10	2.00e-57	213.00
IUUC-Dor-030891	Dipodomys ordii	34.57	3.00e-29	122.00
IUUC-Dse-031170	Dothistroma septosporum	62.05	5.00e-102	362.00
IUUC-Dme-031677	Drosophila melanogaster	39.13	2.00e-51	194.00
IUUC-Ete-032646	Echinops telfairi	39.11	8.00e-28	117.00
IUUC-Eca-033776	Equus caballus	38.14	8.00e-51	192.00
IUUC-Eeu-035305	Erinaceus europaeus	36.84	4.00e-30	123.00
IUUC-Fca-035846	Felis catus	35.99	3.00e-53	200.00
IUUC-Fal-037597	Ficedula albicollis	37.11	7.00e-50	189.00
IUUC-Fox-037670	Fusarium oxysporum	79.41	3.00e-129	452.00
IUUC-Fso-038243	Fusarium solani	80.84	5.00e-132	461.00
IUUC-Gmo-038499	Gadus morhua	35.90	7.00e-50	189.00
IUUC-Ggr-039975	Gaeumannomyces graminis	64.89	9.00e-105	371.00
IUUC-Gga-040904	Gallus gallus	38.78	3.00e-58	217.00
IUUC-Gac-042058	Gasterosteus aculeatus	39.03	3.00e-56	210.00
IUUC-Gma-043763	Glycine max	38.96	2.00e-55	207.00
IUUC-Ggo-044699	Gorilla gorilla	44.87	4.00e-54	203.00
IUUC-Hsa-046227	Homo sapiens	39.10	9.00e-58	215.00
IUUC-Hvu-047359	Hordeum vulgare	37.73	6.00e-56	209.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	35.86	1.00e-52	198.00
IUUC-Lch-049829	Latimeria chalumnae	39.10	3.00e-58	216.00
IUUC-Lpe-050899	Leersia perrieri	39.18	4.00e-56	209.00
IUUC-Loc-052264	Lepisosteus oculatus	39.55	3.00e-57	213.00
IUUC-Lma-053110	Leptosphaeria maculans	67.01	1.00e-100	358.00
IUUC-Laf-053639	Loxodonta africana	39.10	1.00e-57	214.00
IUUC-Mcc-055506	Macaca mulatta	38.59	3.00e-57	214.00
IUUC-Meu-056267	Macropus eugenii	38.21	8.00e-35	140.00
IUUC-Mor-057001	Magnaporthe oryzae	64.55	2.00e-106	377.00
IUUC-Mpo-057608	Magnaporthe poae	71.35	2.00e-69	253.00
IUUC-Mtr-057731	Medicago truncatula	39.58	1.00e-58	218.00
IUUC-Mla-059016	Melampsora laricipopulina	41.26	9.00e-40	154.00
IUUC-Mga-060178	Meleagris gallopavo	37.80	2.00e-51	194.00
IUUC-Mvi-060353	Microbotryum violaceum	36.68	1.00e-51	194.00
IUUC-Mmr-060738	Microcebus murinus	38.78	3.00e-57	213.00
IUUC-Mdo-062266	Monodelphis domestica	43.40	3.00e-45	172.00
IUUC-Mmu-063619	Mus musculus	38.78	1.00e-57	215.00
IUUC-Mac-065301	Musa acuminata	41.31	4.00e-57	213.00
IUUC-Mpu-066058	Mustela putorius furo	39.10	1.00e-57	214.00
IUUC-Mlu-067292	Myotis lucifugus	39.23	1.00e-57	214.00
IUUC-Nfi-068275	Neosartorya fischeri	61.62	3.00e-105	373.00
IUUC-Ncr-068713	Neurospora crassa	68.06	5.00e-124	435.00
IUUC-Nle-069013	Nomascus leucogenys	38.59	9.00e-57	212.00
IUUC-Opr-070628	Ochotona princeps	34.22	2.00e-48	184.00
IUUC-Ont-072688	Oreochromis niloticus	39.10	1.00e-55	207.00
IUUC-Oan-073004	Ornithorhynchus anatinus	43.66	2.00e-46	177.00
IUUC-Ocu-074303	Oryctolagus cuniculus	39.10	6.00e-57	213.00
IUUC-Oba-075002	Oryza barthii	37.58	2.00e-55	207.00
IUUC-Obr-076392	Oryza brachyantha	36.96	7.00e-55	205.00
IUUC-Ogl-077271	Oryza glaberrima	37.58	2.00e-55	207.00
IUUC-Ogu-078493	Oryza glumaepatula	37.89	2.00e-56	210.00
IUUC-Oin-080084	Oryza indica	37.89	2.00e-56	210.00
IUUC-Olo-080803	Oryza longistaminata	37.89	3.00e-56	210.00
IUUC-Ome-081146	Oryza meridionalis	37.89	4.00e-56	209.00
IUUC-Oni-082146	Oryza nivara	37.89	2.00e-56	210.00
IUUC-Opu-083633	Oryza punctata	38.20	5.00e-56	209.00
IUUC-Oru-084789	Oryza rufipogon	37.89	2.00e-56	210.00
IUUC-Osa-086196	Oryza sativa	37.89	2.00e-56	210.00
IUUC-Ola-087126	Oryzias latipes	39.68	2.00e-57	214.00
IUUC-Olu-087665	Ostreococcus lucimarinus	40.50	8.00e-53	198.00
IUUC-Oga-089140	Otolemur garnettii	35.69	2.00e-52	197.00
IUUC-Oar-090296	Ovis aries	38.78	4.00e-56	209.00
IUUC-Ptr-090566	Pan troglodytes	39.10	9.00e-58	215.00
IUUC-Pan-092052	Papio anubis	38.59	3.00e-57	213.00
IUUC-Psi-093723	Pelodiscus sinensis	37.46	1.00e-50	191.00
IUUC-Pma-094568	Petromyzon marinus	45.75	5.00e-45	172.00
IUUC-Pno-095120	Phaeosphaeria nodorum	65.16	2.00e-103	367.00
IUUC-Ppa-095761	Physcomitrella patens	37.46	6.00e-53	199.00
IUUC-Pfo-096210	Poecilia formosa	39.35	3.00e-57	213.00
IUUC-Pab-098463	Pongo abelii	39.10	8.00e-58	215.00
IUUC-Pop-099423	Populus trichocarpa	38.34	3.00e-53	200.00
IUUC-Pca-100108	Procavia capensis	44.07	3.00e-51	193.00
IUUC-Ppe-101176	Prunus persica	39.88	4.00e-54	203.00
IUUC-Pva-102629	Pteropus vampyrus	44.87	4.00e-52	196.00
IUUC-Pgr-103419	Puccinia graminis	38.98	4.00e-43	166.00
IUUC-Pte-104207	Pyrenophora teres	65.70	1.00e-55	206.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	66.56	5.00e-110	388.00
IUUC-Rno-105579	Rattus norvegicus	33.33	1.00e-46	178.00
IUUC-Sha-106894	Sarcophilus harrisii	37.50	4.00e-46	176.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	46.62	2.00e-73	266.00
IUUC-Spo-108371	Schizosaccharomyces pombe	51.03	1.00e-79	287.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	65.62	1.00e-94	337.00
IUUC-Smo-109396	Selaginella moellendorffii	39.56	1.00e-53	201.00
IUUC-Sit-110630	Setaria italica	37.74	2.00e-54	204.00
IUUC-Sly-110972	Solanum lycopersicum	37.66	3.00e-52	196.00
IUUC-Stu-112185	Solanum tuberosum	39.26	5.00e-60	223.00
IUUC-Sar-113294	Sorex araneus	33.92	2.00e-46	177.00
IUUC-Sbi-113951	Sorghum bicolor	37.74	3.00e-55	206.00
IUUC-Ssc-115501	Sus scrofa	38.00	1.00e-52	198.00
IUUC-Tgu-117152	Taeniopygia guttata	37.11	7.00e-50	189.00
IUUC-Tru-118388	Takifugu rubripes	39.10	5.00e-57	212.00
IUUC-Tsy-119109	Tarsius syrichta	39.10	1.00e-57	214.00
IUUC-Tni-120048	Tetraodon nigroviridis	39.10	2.00e-57	214.00
IUUC-Tca-121750	Theobroma cacao	38.11	5.00e-56	209.00
IUUC-Tvi-122284	Trichoderma virens	87.96	1.00e-140	490.00
IUUC-Tae-124082	Triticum aestivum	38.04	9.00e-57	212.00
IUUC-Tur-126366	Triticum urartu	33.55	5.00e-37	146.00
IUUC-Tme-127187	Tuber melanosporum	61.26	4.00e-105	372.00
IUUC-Tbe-127705	Tupaia belangeri	39.84	6.00e-33	132.00
IUUC-Ttr-128867	Tursiops truncatus	38.91	2.00e-41	160.00
IUUC-Vda-129912	Verticillium dahliae	63.43	7.00e-107	378.00
IUUC-Vpa-130552	Vicugna pacos	44.60	8.00e-47	179.00
IUUC-Vvi-130881	Vitis vinifera	38.04	9.00e-51	192.00
IUUC-Xtr-131934	Xenopus tropicalis	38.78	2.00e-56	211.00
IUUC-Xma-133312	Xiphophorus maculatus	39.35	4.00e-57	213.00
IUUC-Yli-134487	Yarrowia lipolytica	44.59	8.00e-66	241.00
IUUC-Zma-135639	Zea mays	38.41	3.00e-45	174.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence