iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bra-016910

Ensembl Protein ID

Bra010392.1-P

UniProt Accession

M4D1P2; M4D1P2_BRARP

Protein Name

E3 ubiquitin-protein ligase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bra010392	Bra010392.1	Bra010392.1-P

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	90.18	2.00e-173	605.00	IUUC-Ath-007192
E3 activity/RING/RING	36.82	7.00e-40	162.00	IUUC-Hsa-046357

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Brassica rapa

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

METESMDCES STRSITNDNG TYHFSSTKNH AGAAAVVTNI VGPTTTAAAT SVYELLECPL 60
CTFSMYPPIH QCHNGHTLCS TCKVRVHNRC PTCRQELGDI RCLALEKVAE SLELPCKYYN 120

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Nucleotide Sequence
(Fasta)

ATGGAGACAG AGAGTATGGA CTGCGAATCG TCGACGAGAA GCATCACCAA CGATAACGGA 60
ACTTACCATT TCTCTTCCAC GAAGAATCAC GCCGGAGCTG CTGCCGTCGT TACCAATATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003813	Anas platyrhynchos	36.82	2.00e-41	162.00
IUUC-Aca-005014	Anolis carolinensis	36.82	2.00e-41	162.00
IUUC-Aly-006522	Arabidopsis lyrata	90.49	4.00e-175	606.00
IUUC-Ath-007192	Arabidopsis thaliana	90.18	1.00e-174	605.00
IUUC-Bta-012887	Bos taurus	36.82	2.00e-41	162.00
IUUC-Bdi-014729	Brachypodium distachyon	86.91	7.00e-149	519.00
IUUC-Bol-015983	Brassica oleracea	96.57	0.00e+00	649.00
IUUC-Cja-019796	Callithrix jacchus	36.82	3.00e-41	162.00
IUUC-Cpo-022348	Cavia porcellus	36.82	2.00e-41	162.00
IUUC-Csa-023974	Chlorocebus sabaeus	36.82	2.00e-41	162.00
IUUC-Dno-029764	Dasypus novemcinctus	36.82	2.00e-41	162.00
IUUC-Dor-030489	Dipodomys ordii	31.35	1.00e-19	89.00
IUUC-Eca-033536	Equus caballus	36.82	2.00e-41	162.00
IUUC-Fal-037487	Ficedula albicollis	36.82	1.00e-41	162.00
IUUC-Gga-040269	Gallus gallus	36.82	2.00e-41	162.00
IUUC-Gac-042282	Gasterosteus aculeatus	36.82	6.00e-42	163.00
IUUC-Ggo-045444	Gorilla gorilla	36.82	2.00e-41	162.00
IUUC-Hsa-046357	Homo sapiens	36.82	2.00e-41	162.00
IUUC-Itr-048046	Ictidomys tridecemlineatus	36.82	2.00e-41	162.00
IUUC-Lch-049504	Latimeria chalumnae	36.82	2.00e-41	162.00
IUUC-Laf-053668	Loxodonta africana	36.82	2.00e-41	162.00
IUUC-Mcc-054640	Macaca mulatta	36.82	2.00e-41	162.00
IUUC-Mtr-058699	Medicago truncatula	79.75	3.00e-154	536.00
IUUC-Mga-059503	Meleagris gallopavo	36.82	3.00e-41	162.00
IUUC-Mmr-060794	Microcebus murinus	36.82	2.00e-41	162.00
IUUC-Mmu-063876	Mus musculus	36.82	2.00e-41	162.00
IUUC-Mac-065670	Musa acuminata	79.06	2.00e-153	534.00
IUUC-Mpu-066488	Mustela putorius furo	36.82	2.00e-41	162.00
IUUC-Mlu-067207	Myotis lucifugus	36.82	1.00e-41	162.00
IUUC-Nle-069706	Nomascus leucogenys	36.82	2.00e-41	162.00
IUUC-Ont-071849	Oreochromis niloticus	36.82	7.00e-42	163.00
IUUC-Oba-075289	Oryza barthii	87.89	6.00e-138	483.00
IUUC-Obr-076037	Oryza brachyantha	79.06	7.00e-133	466.00
IUUC-Ogl-077148	Oryza glaberrima	83.59	1.00e-132	465.00
IUUC-Ogu-078042	Oryza glumaepatula	82.63	1.00e-132	465.00
IUUC-Oin-079325	Oryza indica	83.59	1.00e-132	464.00
IUUC-Olo-080244	Oryza longistaminata	83.59	8.00e-133	467.00
IUUC-Oni-082163	Oryza nivara	83.59	1.00e-132	465.00
IUUC-Oru-084833	Oryza rufipogon	83.59	1.00e-132	464.00
IUUC-Osa-085316	Oryza sativa	83.59	1.00e-132	464.00
IUUC-Ola-086814	Oryzias latipes	36.82	6.00e-42	163.00
IUUC-Oar-089323	Ovis aries	36.82	2.00e-41	162.00
IUUC-Pan-092012	Papio anubis	36.82	2.00e-41	162.00
IUUC-Pfo-097134	Poecilia formosa	36.82	6.00e-42	163.00
IUUC-Pab-097555	Pongo abelii	36.82	2.00e-41	162.00
IUUC-Pop-100033	Populus trichocarpa	77.41	2.00e-154	538.00
IUUC-Ppe-101960	Prunus persica	78.27	3.00e-157	546.00
IUUC-Pva-103132	Pteropus vampyrus	23.93	8.00e-11	60.50
IUUC-Sha-106547	Sarcophilus harrisii	37.40	2.00e-41	162.00
IUUC-Sit-110245	Setaria italica	79.50	7.00e-133	466.00
IUUC-Stu-112571	Solanum tuberosum	86.28	3.00e-148	517.00
IUUC-Sbi-114035	Sorghum bicolor	79.06	3.00e-133	467.00
IUUC-Tgu-116579	Taeniopygia guttata	36.82	2.00e-41	162.00
IUUC-Tru-118250	Takifugu rubripes	36.05	5.00e-40	157.00
IUUC-Tni-120488	Tetraodon nigroviridis	37.35	1.00e-39	155.00
IUUC-Tca-121517	Theobroma cacao	78.70	1.00e-157	548.00
IUUC-Tur-126259	Triticum urartu	72.33	4.00e-132	463.00
IUUC-Ttr-129166	Tursiops truncatus	37.30	4.00e-39	155.00
IUUC-Vpa-130799	Vicugna pacos	32.16	1.00e-18	85.50
IUUC-Xtr-132553	Xenopus tropicalis	36.82	1.00e-41	162.00
IUUC-Xma-133670	Xiphophorus maculatus	36.82	6.00e-42	163.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence