iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049646

Ensembl Protein ID

ENSLACP00000008916.2

UniProt Accession

H3AGZ5; H3AGZ5_LATCH

Genbank Protein ID

ENSLACP00000008916

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01056242

Gene Name

KEAP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000007874.2	ENSLACT00000008985.2	ENSLACP00000008916.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.10e-16	60.2	45	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.50e-08	33.8	148	178

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvg....geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l +     + ef ahkivLa+sS+vF+a+f+++l+e    + v i+++ p+v++ l++F Yt +++ 
   Q: 45   CDVTLRLRyndlRAEFVAHKIVLASSSPVFKAMFTNGLKECG-MEVVPIEGIHPKVMERLIEFAYTASISV 114
           899999955569*****************************9.***********************98875 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++N++gi  fA++ +c +L+++a+++i  hF
   Q: 148  PSNAIGIANFAEQIGCMELHQKAREYIYMHF 178
           89***************************** PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MYATECKAEV TPSQNGNRYF HYTLQNHTKQ AFAVMNELRL SRQLCDVTLR LRYNDLRAEF 60
VAHKIVLASS SPVFKAMFTN GLKECGMEVV PIEGIHPKVM ERLIEFAYTA SISVGEKCVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACTCCCCGC TTCGGCTGCC GCCGCGCTGC GATGGAGGAG CTGCAGCCGG GCTGAGGCGC 60
TTCTCTCGTC GGTCTCCACA CTTTCTCCGG AGAGAGCGAC CAACCACACC ACAGGCGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR030563--KEAP1
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0071379--P:cellular response to prostaglandin stimulus
GO:0071466--P:cellular response to xenobiotic stimulus
GO:0016567--P:protein ubiquitination

KEGG

lcm:102349551

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001377	Ailuropoda melanoleuca	83.39	0.00e+00	1046.00
IUUC-Atr-002726	Amborella trichopoda	31.14	2.00e-42	167.00
IUUC-Aca-005389	Anolis carolinensis	84.17	0.00e+00	1042.00
IUUC-Ame-010749	Astyanax mexicanus	82.28	0.00e+00	1007.00
IUUC-Bta-013505	Bos taurus	83.22	0.00e+00	1044.00
IUUC-Cja-018823	Callithrix jacchus	82.54	0.00e+00	1035.00
IUUC-Cfa-021202	Canis familiaris	83.39	0.00e+00	1047.00
IUUC-Cpo-021830	Cavia porcellus	82.15	0.00e+00	727.00
IUUC-Csa-023728	Chlorocebus sabaeus	83.05	0.00e+00	1046.00
IUUC-Cin-025195	Ciona intestinalis	56.94	0.00e+00	696.00
IUUC-Csv-026155	Ciona savignyi	54.91	0.00e+00	637.00
IUUC-Dre-027388	Danio rerio	80.52	0.00e+00	983.00
IUUC-Dno-029066	Dasypus novemcinctus	73.90	0.00e+00	902.00
IUUC-Dor-030674	Dipodomys ordii	82.11	0.00e+00	723.00
IUUC-Dme-032165	Drosophila melanogaster	49.65	2.00e-162	566.00
IUUC-Eca-034381	Equus caballus	80.41	0.00e+00	1014.00
IUUC-Eeu-034791	Erinaceus europaeus	84.44	0.00e+00	720.00
IUUC-Fca-036067	Felis catus	82.88	0.00e+00	1040.00
IUUC-Gmo-039691	Gadus morhua	80.34	0.00e+00	977.00
IUUC-Gga-040266	Gallus gallus	80.55	0.00e+00	995.00
IUUC-Gac-041866	Gasterosteus aculeatus	80.69	0.00e+00	983.00
IUUC-Ggo-044719	Gorilla gorilla	82.88	0.00e+00	1041.00
IUUC-Hsa-046255	Homo sapiens	82.88	0.00e+00	1041.00
IUUC-Itr-048457	Ictidomys tridecemlineatus	83.05	0.00e+00	1040.00
IUUC-Lpe-051276	Leersia perrieri	34.62	2.00e-41	164.00
IUUC-Laf-054579	Loxodonta africana	83.39	0.00e+00	1048.00
IUUC-Mcc-055315	Macaca mulatta	83.05	0.00e+00	1046.00
IUUC-Meu-056288	Macropus eugenii	79.97	0.00e+00	984.00
IUUC-Mmr-061639	Microcebus murinus	82.54	0.00e+00	1040.00
IUUC-Mdo-062072	Monodelphis domestica	84.72	0.00e+00	1064.00
IUUC-Mmu-063622	Mus musculus	81.86	0.00e+00	1028.00
IUUC-Mpu-066737	Mustela putorius furo	84.27	0.00e+00	1025.00
IUUC-Mlu-068173	Myotis lucifugus	83.22	0.00e+00	1043.00
IUUC-Nle-069336	Nomascus leucogenys	49.83	4.00e-149	521.00
IUUC-Opr-070432	Ochotona princeps	83.90	0.00e+00	1050.00
IUUC-Ont-072160	Oreochromis niloticus	80.30	0.00e+00	977.00
IUUC-Oan-072691	Ornithorhynchus anatinus	74.96	0.00e+00	909.00
IUUC-Ocu-073798	Oryctolagus cuniculus	83.30	0.00e+00	1045.00
IUUC-Obr-076181	Oryza brachyantha	32.69	1.00e-35	145.00
IUUC-Ola-086367	Oryzias latipes	77.70	0.00e+00	941.00
IUUC-Oga-088231	Otolemur garnettii	83.05	0.00e+00	1042.00
IUUC-Oar-089227	Ovis aries	82.03	0.00e+00	1022.00
IUUC-Ptr-091460	Pan troglodytes	82.88	0.00e+00	1041.00
IUUC-Pan-092713	Papio anubis	83.05	0.00e+00	1046.00
IUUC-Pfo-096468	Poecilia formosa	81.16	0.00e+00	983.00
IUUC-Pab-098357	Pongo abelii	82.88	0.00e+00	1041.00
IUUC-Pca-100837	Procavia capensis	82.54	0.00e+00	1033.00
IUUC-Pva-103249	Pteropus vampyrus	80.17	0.00e+00	978.00
IUUC-Rno-106086	Rattus norvegicus	80.34	0.00e+00	1008.00
IUUC-Sha-107245	Sarcophilus harrisii	84.55	0.00e+00	1066.00
IUUC-Sar-112985	Sorex araneus	82.16	0.00e+00	1027.00
IUUC-Ssc-115756	Sus scrofa	83.22	0.00e+00	1044.00
IUUC-Tgu-116838	Taeniopygia guttata	54.92	2.00e-121	428.00
IUUC-Tru-117644	Takifugu rubripes	81.72	0.00e+00	1001.00
IUUC-Tni-120245	Tetraodon nigroviridis	81.21	0.00e+00	991.00
IUUC-Tbe-127472	Tupaia belangeri	80.58	2.00e-122	433.00
IUUC-Ttr-128953	Tursiops truncatus	84.40	3.00e-164	571.00
IUUC-Vpa-130683	Vicugna pacos	82.50	0.00e+00	933.00
IUUC-Xtr-132827	Xenopus tropicalis	77.84	0.00e+00	975.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence