iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-019397

UUCD1 version

UUC-CaJ-00692

Ensembl Protein ID

ENSCJAP00000006628.2

UniProt Accession

F7HB59; F7HB59_CALJA

Genbank Protein ID

JAB07158.1; JAB07159.1; JAB19474.1; JAB19475.1; JAB33000.1; JAB33001.1; JAB33002.1; JAB37879.1; JAB37880.1; JAB50206.1; JAB50207.1

Protein Name

E3 ubiquitin-protein ligase RNF146 isoform b

Genbank Nucleotide ID

ACFV01004087; GAMT01004702; GAMS01003662; GAMS01003661; GAMR01000932; GAMR01000931; GAMR01000930; GAMQ01003972; GAMQ01003971; GAMP01002549; GAMP01002548

Gene Name

RNF146

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000003662.2	ENSCJAT00000006998.2	ENSCJAP00000006628.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	99.72	1.00e-165	580.00	IUUC-Hsa-045790

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MMAGCGEIDH SINMLPTNRK ANESCSNTAP SLTVPECAIC LQTCVHPVSL PCKHVFCYLC 60
VKGASWLGKR CALCRQEIPE DFLDKPTLLS PEELKAASRG NGEYAWYYEG RNGWWQYDER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCGTCCCC GGCCGCTGCG GGCTCAGAGG CCGGAGAGAA AAAGACTGCG AGGTGTCCGC 60
TGCTGTGGCC AGAGAGGTGG CAGTCGGAGC GAGGCCCTGT CGGGGGAGCA GGGAGAACTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome

Interpro

IPR033509--RNF146
IPR004170--WWE-dom
IPR018123--WWE-dom_subgr
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50918--WWE
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02825--WWE

SMART

SM00184--RING
SM00678--WWE

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0016874--F:ligase activity
GO:0072572--F:poly-ADP-D-ribose binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0016055--P:Wnt signaling pathway

KEGG

cjc:100399544

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002237	Ailuropoda melanoleuca	91.64	2.00e-155	541.00
IUUC-Apl-004143	Anas platyrhynchos	84.72	8.00e-135	473.00
IUUC-Aca-004557	Anolis carolinensis	81.44	7.00e-128	449.00
IUUC-Ame-011088	Astyanax mexicanus	61.09	2.00e-83	302.00
IUUC-Bta-012639	Bos taurus	93.04	6.00e-151	526.00
IUUC-Cel-018462	Caenorhabditis elegans	28.35	6.00e-19	87.00
IUUC-Cfa-021140	Canis familiaris	91.92	3.00e-167	580.00
IUUC-Cpo-021387	Cavia porcellus	90.81	3.00e-167	580.00
IUUC-Csa-023503	Chlorocebus sabaeus	94.43	1.00e-157	548.00
IUUC-Cho-024895	Choloepus hoffmanni	94.08	2.00e-145	508.00
IUUC-Cin-025455	Ciona intestinalis	51.92	4.00e-43	167.00
IUUC-Dre-028824	Danio rerio	45.99	1.00e-82	299.00
IUUC-Dno-029269	Dasypus novemcinctus	95.54	2.00e-162	564.00
IUUC-Dor-030592	Dipodomys ordii	94.44	4.00e-165	573.00
IUUC-Dme-031618	Drosophila melanogaster	57.33	1.00e-55	210.00
IUUC-Ete-032478	Echinops telfairi	92.76	2.00e-163	568.00
IUUC-Eca-033389	Equus caballus	96.65	0.00e+00	627.00
IUUC-Fca-035488	Felis catus	96.37	7.00e-164	569.00
IUUC-Fal-037087	Ficedula albicollis	83.89	2.00e-154	538.00
IUUC-Gga-040401	Gallus gallus	85.83	5.00e-139	486.00
IUUC-Gac-042412	Gasterosteus aculeatus	64.53	1.00e-87	316.00
IUUC-Ggo-045417	Gorilla gorilla	98.76	4.00e-159	553.00
IUUC-Hsa-045790	Homo sapiens	99.72	4.00e-167	580.00
IUUC-Itr-048820	Ictidomys tridecemlineatus	95.25	4.00e-166	577.00
IUUC-Lch-049493	Latimeria chalumnae	69.08	4.00e-111	394.00
IUUC-Loc-052927	Lepisosteus oculatus	60.00	1.00e-101	362.00
IUUC-Laf-053904	Loxodonta africana	94.15	1.00e-160	559.00
IUUC-Mcc-055427	Macaca mulatta	94.44	2.00e-164	571.00
IUUC-Mmr-060580	Microcebus murinus	97.22	7.00e-160	556.00
IUUC-Mdo-062094	Monodelphis domestica	96.97	1.00e-78	284.00
IUUC-Mmu-063363	Mus musculus	92.76	1.00e-165	575.00
IUUC-Mpu-066816	Mustela putorius furo	95.54	2.00e-158	551.00
IUUC-Mlu-067433	Myotis lucifugus	95.26	0.00e+00	626.00
IUUC-Nle-068986	Nomascus leucogenys	98.89	5.00e-180	623.00
IUUC-Ont-072670	Oreochromis niloticus	58.42	4.00e-81	295.00
IUUC-Oan-073330	Ornithorhynchus anatinus	87.06	3.00e-107	380.00
IUUC-Ocu-074161	Oryctolagus cuniculus	93.89	7.00e-165	573.00
IUUC-Ola-086902	Oryzias latipes	58.91	4.00e-84	304.00
IUUC-Oga-089159	Otolemur garnettii	94.71	0.00e+00	640.00
IUUC-Oar-089586	Ovis aries	94.43	9.00e-147	512.00
IUUC-Ptr-090987	Pan troglodytes	99.72	4.00e-167	580.00
IUUC-Pan-091867	Papio anubis	94.43	2.00e-163	568.00
IUUC-Psi-094024	Pelodiscus sinensis	85.28	3.00e-142	498.00
IUUC-Pma-094453	Petromyzon marinus	63.91	5.00e-65	241.00
IUUC-Pfo-097108	Poecilia formosa	70.73	1.00e-83	303.00
IUUC-Pab-097997	Pongo abelii	97.77	5.00e-173	600.00
IUUC-Pca-100260	Procavia capensis	92.18	6.00e-164	569.00
IUUC-Pva-103140	Pteropus vampyrus	94.72	1.00e-165	575.00
IUUC-Rno-105795	Rattus norvegicus	86.94	1.00e-163	568.00
IUUC-Sha-107033	Sarcophilus harrisii	88.61	5.00e-156	543.00
IUUC-Ssc-116395	Sus scrofa	96.94	1.00e-180	625.00
IUUC-Tgu-116685	Taeniopygia guttata	81.06	2.00e-135	474.00
IUUC-Tru-118014	Takifugu rubripes	74.88	6.00e-84	303.00
IUUC-Tsy-119326	Tarsius syrichta	90.28	1.00e-177	615.00
IUUC-Tni-120322	Tetraodon nigroviridis	69.95	4.00e-82	298.00
IUUC-Tbe-128067	Tupaia belangeri	96.11	5.00e-172	596.00
IUUC-Ttr-128530	Tursiops truncatus	96.94	3.00e-165	574.00
IUUC-Vpa-130322	Vicugna pacos	97.77	4.00e-172	597.00
IUUC-Xtr-132606	Xenopus tropicalis	66.20	1.00e-118	419.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence