iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-025931

UUCD1 version

UUC-CiS-00470

Ensembl Protein ID

ENSCSAVP00000006287.1

UniProt Accession

H2YLT5; H2YLT5_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000003765.1	ENSCSAVT00000006365.1	ENSCSAVP00000006286.1
ENSCSAVG00000003765.1	ENSCSAVT00000006366.1	ENSCSAVP00000006287.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.70e-79	266.8	3	664

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 40   enpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk....eknkpkeeeeeedk 123
           +np +  g+++k++  +++ lw+++k+a+sp+e++++++ + ++f+  +q+DaqEf+aflld l+e+l+     ++ ++  + eee++
   Q: 3    KNPLGVGGRMAKAFYVVVRRLWDGSKQAFSPHEFKDVVGLKDSRFTDGMQHDAQEFMAFLLDMLHEDLNTatgpHTVEQPRKCEEESE 90
           56667778999*********************************************************98888855555555666677 PP
   S: 124  selsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke.......................... 185
           +++  +a++++ ++  s+i+++F+g l+s++ cl+c+++s +++pfl l++p+p+k +  +                           
   Q: 91   EKMATDAWRSHVSRAGSFIVENFHGMLQSELECLKCKTKSIKFDPFLFLPVPLPKKVQPFTViffqsnpsppikitvpvltdgpkaie 178
           889999************************************************99977555************************** PP
   S: 186  ........................................................................................ 185
                                                                                                   
   Q: 179  mltqvarhtgtcinnllsyevsnctiqrffipsspldcssktstvhvqevmsheeigepvyqiickqwksvpdirqqcvmcnrkpddt 266
           **************************************************************************************** PP
   S: 186  ........................................................................................ 185
                                                                                                   
   Q: 267  felkrcmnclavaycnrncqkdhwlkhrvvcrrrlqlvgqpfvmcitessatytnvkalafewsnkntkffllvlnpikkktvtyesc 354
           **************************************************************************************** PP
   S: 186  ........................................................................................ 185
                                                                                                   
   Q: 355  ancvfycmftqfqnaqrtsvqsillinpyfklmvnlmriwhsfnncvyffytlisskkfksskkrgeilkkktcyfsifnsskkrgei 442
           **************************************************************************************** PP
   S: 186  ....................................................................slqdcLesftkeeelegenk 205
                                                                               +l++cL+ f ++e l ++++
   Q: 443  lkkqlvifqsfclnfsgdiplnflkdlfislvwqnkksiaksvtvsnkpldfsqpsrcvdlmeksskhDLHKCLDLFIEPEVLSQDEA 530
           **************************************************************************************** PP
   S: 206  yycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslss 292
           +yc+kckk+ +a+kk++l+ lP+vLi++LkRfsf+++ +++ ki+  +++p + Ld+s +c++p +++  + +Y+L+av++H+G++ +
   Q: 531  WYCPKCKKHMQAVKKMSLWDLPDVLIVQLKRFSFKNYLWRD-KISMFIDMPVKnLDMSTYCNNPRKTK--SMSYDLFAVINHHGGILG 615
           *************************************8886.*********999*********99988..9***************** PP
   S: 293  GHYvayvknekgk........WllfdDskVtevkeeevleetgstaYvlfYkr 337
           GHY+++v+  + +        W ++dDs+Vt+++ + v e     aYv+fY r
   Q: 616  GHYTTDVRLPDIQdttssivdWRTCDDSRVTKLNRKIVTE----AAYVMFYLR 664
           *********666666778999************8666666....9******76 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

NTKNPLGVGG RMAKAFYVVV RRLWDGSKQA FSPHEFKDVV GLKDSRFTDG MQHDAQEFMA 60
FLLDMLHEDL NTATGPHTVE QPRKCEEESE EKMATDAWRS HVSRAGSFIV ENFHGMLQSE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTCTCAGCA ATCTCGGCAA CACCTGCTTC ATGAACAGCG TCATCCAAGC GCTCGCCAAC 60
ACACCACAAC TTCAACAATA TTTCCTCGGT GAGCATTTCC CTATGACTCA TTTCCGTTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR002893--Znf_MYND

PROSITE

PS00973--USP_2
PS50235--USP_3
PS01360--ZF_MYND_1
PS50865--ZF_MYND_2

Pfam

PF00443--UCH
PF01753--zf-MYND

Gene Ontology

GO:0046872--F:metal ion binding
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001999	Ailuropoda melanoleuca	35.86	4.00e-120	424.00
IUUC-Bta-012905	Bos taurus	36.73	1.00e-121	430.00
IUUC-Cja-018789	Callithrix jacchus	36.01	1.00e-119	423.00
IUUC-Cfa-021004	Canis familiaris	36.30	7.00e-121	427.00
IUUC-Cpo-021529	Cavia porcellus	36.34	2.00e-119	422.00
IUUC-Csa-024035	Chlorocebus sabaeus	36.59	1.00e-121	429.00
IUUC-Cin-025451	Ciona intestinalis	66.97	7.00e-136	476.00
IUUC-Dre-028556	Danio rerio	39.59	7.00e-63	234.00
IUUC-Dno-029240	Dasypus novemcinctus	46.19	5.00e-57	216.00
IUUC-Dor-030495	Dipodomys ordii	34.06	1.00e-94	340.00
IUUC-Ete-032741	Echinops telfairi	35.86	8.00e-118	417.00
IUUC-Eca-033661	Equus caballus	36.59	8.00e-122	430.00
IUUC-Eeu-034648	Erinaceus europaeus	46.15	1.00e-52	200.00
IUUC-Fca-035646	Felis catus	36.30	2.00e-121	429.00
IUUC-Ggo-044708	Gorilla gorilla	36.44	2.00e-120	425.00
IUUC-Hsa-046791	Homo sapiens	36.73	3.00e-122	432.00
IUUC-Itr-048892	Ictidomys tridecemlineatus	36.30	6.00e-117	414.00
IUUC-Laf-053788	Loxodonta africana	35.37	2.00e-117	416.00
IUUC-Mcc-055693	Macaca mulatta	36.59	2.00e-121	429.00
IUUC-Mmr-060802	Microcebus murinus	36.30	1.00e-118	419.00
IUUC-Mmu-063874	Mus musculus	36.59	3.00e-122	431.00
IUUC-Mpu-066166	Mustela putorius furo	36.44	3.00e-121	428.00
IUUC-Nle-070161	Nomascus leucogenys	36.59	2.00e-121	429.00
IUUC-Opr-071015	Ochotona princeps	35.86	6.00e-116	410.00
IUUC-Ocu-073938	Oryctolagus cuniculus	36.30	3.00e-117	415.00
IUUC-Oga-088297	Otolemur garnettii	36.44	1.00e-120	426.00
IUUC-Oar-089675	Ovis aries	35.77	6.00e-110	390.00
IUUC-Ptr-091621	Pan troglodytes	36.43	5.00e-121	427.00
IUUC-Pan-092118	Papio anubis	36.59	2.00e-121	429.00
IUUC-Pma-094169	Petromyzon marinus	41.06	1.00e-40	159.00
IUUC-Pab-098551	Pongo abelii	36.44	6.00e-120	424.00
IUUC-Pca-100158	Procavia capensis	36.20	1.00e-120	426.00
IUUC-Pva-103160	Pteropus vampyrus	36.43	6.00e-120	424.00
IUUC-Rno-105355	Rattus norvegicus	36.73	3.00e-122	432.00
IUUC-Ssl-108506	Sclerotinia sclerotiorum	33.33	5.00e-16	77.80
IUUC-Ssc-115761	Sus scrofa	36.73	4.00e-122	431.00
IUUC-Tgu-116956	Taeniopygia guttata	46.43	2.00e-52	199.00
IUUC-Tru-118739	Takifugu rubripes	39.77	9.00e-65	241.00
IUUC-Tbe-128017	Tupaia belangeri	34.55	2.00e-110	392.00
IUUC-Ttr-128869	Tursiops truncatus	36.30	5.00e-121	427.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence