iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034403

UUCD1 version

UUC-EqC-00730

Ensembl Protein ID

ENSECAP00000011405.1

UniProt Accession

F7BNS9; F7BNS9_HORSE

Protein Name

Uncharacterized protein

Gene Name

RFWD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000013304.1	ENSECAT00000014284.1	ENSECAP00000011405.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.60e-22	77.7	334	363
E3 activity/RING/RING	8.10e-06	26.4	1	38

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 3    tdsvtclaf..sd.tllvsGsdDgtikvWD 29
           +++++c+++     +ll+s+ + gt+ +WD
   Q: 334  NSKISCISWssYHkNLLASSDYEGTVILWD 363
           689******9622599************** PP

E3 activity/RING/RING

   S: 2    aiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           +iC++++++  + + CgH f+ +C+++          + rCP C+
   Q: 1    PICFDMIEE-AYMTKCGHSFCYKCIHQS------LEDNNRCPKCN 38
           8******99.888***********9555......999999****7 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

PICFDMIEEA YMTKCGHSFC YKCIHQSLED NNRCPKCNYV VDNIDHLYPN FLVNELILKQ 60
KQRFEEKRFK LDHSVSSTNG HRWQILQDLL GTDQDNLDLA NVNLMLELLV QKKKQLEAES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTTTAGCC CTATCTGCTT TGATATGATT GAGGAAGCAT ACATGACGAA ATGTGGCCAC 60
AGCTTTTGGT AAGATGACTT TGTTTTAGCG AAATTGTCTT TTGGCAGTTT TTAACTTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00400--WD40

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0010212--P:response to ionizing radiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000885	Aegilops tauschii	39.33	9.00e-121	427.00
IUUC-Aml-001265	Ailuropoda melanoleuca	99.31	0.00e+00	1160.00
IUUC-Atr-002460	Amborella trichopoda	38.10	2.00e-117	416.00
IUUC-Apl-003796	Anas platyrhynchos	98.61	0.00e+00	1156.00
IUUC-Aca-005078	Anolis carolinensis	97.23	0.00e+00	1121.00
IUUC-Aly-006014	Arabidopsis lyrata	39.29	2.00e-122	432.00
IUUC-Ath-007636	Arabidopsis thaliana	39.19	8.00e-122	431.00
IUUC-Ame-011176	Astyanax mexicanus	95.87	8.00e-69	254.00
IUUC-Bta-012595	Bos taurus	99.31	0.00e+00	1161.00
IUUC-Bdi-014152	Brachypodium distachyon	38.59	2.00e-121	429.00
IUUC-Bol-016380	Brassica oleracea	39.68	1.00e-122	433.00
IUUC-Bra-017690	Brassica rapa	38.49	4.00e-117	415.00
IUUC-Cja-018926	Callithrix jacchus	98.96	0.00e+00	1154.00
IUUC-Cfa-021088	Canis familiaris	99.31	0.00e+00	1162.00
IUUC-Cpo-022442	Cavia porcellus	98.79	0.00e+00	1151.00
IUUC-Cre-022579	Chlamydomonas reinhardtii	33.09	4.00e-33	134.00
IUUC-Csa-024119	Chlorocebus sabaeus	99.31	0.00e+00	1160.00
IUUC-Cho-024883	Choloepus hoffmanni	63.76	4.00e-95	342.00
IUUC-Cin-025375	Ciona intestinalis	55.57	0.00e+00	637.00
IUUC-Cme-027350	Cyanidioschyzon merolae	41.33	2.00e-74	274.00
IUUC-Dre-028453	Danio rerio	87.31	0.00e+00	1008.00
IUUC-Dno-029887	Dasypus novemcinctus	98.79	0.00e+00	1154.00
IUUC-Dor-031110	Dipodomys ordii	79.17	0.00e+00	887.00
IUUC-Ete-033016	Echinops telfairi	83.54	0.00e+00	945.00
IUUC-Eeu-034690	Erinaceus europaeus	84.00	0.00e+00	956.00
IUUC-Fca-036475	Felis catus	98.96	0.00e+00	1156.00
IUUC-Fal-037189	Ficedula albicollis	98.27	0.00e+00	1152.00
IUUC-Gmo-039245	Gadus morhua	86.21	0.00e+00	995.00
IUUC-Gga-040806	Gallus gallus	98.27	0.00e+00	1152.00
IUUC-Gac-042177	Gasterosteus aculeatus	87.76	0.00e+00	1026.00
IUUC-Gma-044187	Glycine max	40.45	5.00e-120	424.00
IUUC-Ggo-044430	Gorilla gorilla	98.21	0.00e+00	873.00
IUUC-Hsa-045853	Homo sapiens	98.96	0.00e+00	1155.00
IUUC-Hvu-047750	Hordeum vulgare	37.50	1.00e-86	314.00
IUUC-Itr-048238	Ictidomys tridecemlineatus	100.00	9.00e-144	501.00
IUUC-Lch-050420	Latimeria chalumnae	91.44	0.00e+00	1060.00
IUUC-Lpe-051219	Leersia perrieri	38.62	5.00e-120	425.00
IUUC-Loc-052728	Lepisosteus oculatus	90.55	0.00e+00	1028.00
IUUC-Laf-053775	Loxodonta africana	98.61	0.00e+00	1163.00
IUUC-Meu-056595	Macropus eugenii	77.46	3.00e-176	611.00
IUUC-Mtr-058555	Medicago truncatula	40.22	2.00e-126	446.00
IUUC-Mga-059646	Meleagris gallopavo	98.44	0.00e+00	1153.00
IUUC-Mmr-060990	Microcebus murinus	99.31	0.00e+00	1161.00
IUUC-Mdo-062287	Monodelphis domestica	98.61	0.00e+00	1156.00
IUUC-Mmu-064097	Mus musculus	98.96	0.00e+00	1157.00
IUUC-Mac-065240	Musa acuminata	40.80	7.00e-128	451.00
IUUC-Mpu-066612	Mustela putorius furo	99.13	0.00e+00	1159.00
IUUC-Mlu-067967	Myotis lucifugus	98.79	0.00e+00	1155.00
IUUC-Nle-069543	Nomascus leucogenys	99.13	0.00e+00	1159.00
IUUC-Opr-070366	Ochotona princeps	84.08	0.00e+00	671.00
IUUC-Ont-071522	Oreochromis niloticus	87.24	0.00e+00	1014.00
IUUC-Oan-073409	Ornithorhynchus anatinus	98.96	0.00e+00	1153.00
IUUC-Ocu-073756	Oryctolagus cuniculus	98.96	0.00e+00	1160.00
IUUC-Oba-075149	Oryza barthii	38.00	1.00e-119	424.00
IUUC-Obr-076563	Oryza brachyantha	38.16	9.00e-120	424.00
IUUC-Ogl-077701	Oryza glaberrima	38.00	6.00e-120	424.00
IUUC-Ogu-078383	Oryza glumaepatula	38.00	6.00e-120	424.00
IUUC-Oin-079965	Oryza indica	35.88	3.00e-108	385.00
IUUC-Olo-080639	Oryza longistaminata	37.85	1.00e-117	417.00
IUUC-Ome-081821	Oryza meridionalis	37.58	1.00e-109	390.00
IUUC-Oni-082622	Oryza nivara	38.00	6.00e-120	424.00
IUUC-Opu-083295	Oryza punctata	38.00	9.00e-120	424.00
IUUC-Oru-084661	Oryza rufipogon	38.00	6.00e-120	424.00
IUUC-Osa-085766	Oryza sativa	38.00	6.00e-120	424.00
IUUC-Ola-086727	Oryzias latipes	87.41	0.00e+00	1033.00
IUUC-Olu-087702	Ostreococcus lucimarinus	42.91	2.00e-65	241.00
IUUC-Oga-088215	Otolemur garnettii	99.31	0.00e+00	1160.00
IUUC-Oar-089880	Ovis aries	99.48	0.00e+00	1162.00
IUUC-Ptr-090597	Pan troglodytes	98.96	0.00e+00	1155.00
IUUC-Pan-091987	Papio anubis	99.31	0.00e+00	1160.00
IUUC-Psi-094033	Pelodiscus sinensis	97.55	0.00e+00	1129.00
IUUC-Pma-094587	Petromyzon marinus	70.11	0.00e+00	766.00
IUUC-Ppa-095256	Physcomitrella patens	38.80	9.00e-125	440.00
IUUC-Pfo-097388	Poecilia formosa	86.33	0.00e+00	993.00
IUUC-Pab-098029	Pongo abelii	98.96	0.00e+00	1155.00
IUUC-Pop-099319	Populus trichocarpa	38.52	8.00e-123	434.00
IUUC-Pca-100846	Procavia capensis	90.12	0.00e+00	1049.00
IUUC-Ppe-101250	Prunus persica	37.74	8.00e-113	400.00
IUUC-Pva-102407	Pteropus vampyrus	98.96	0.00e+00	1146.00
IUUC-Rno-105312	Rattus norvegicus	98.96	0.00e+00	1155.00
IUUC-Sha-106514	Sarcophilus harrisii	98.92	0.00e+00	772.00
IUUC-Smo-109418	Selaginella moellendorffii	38.78	1.00e-121	430.00
IUUC-Sit-110248	Setaria italica	38.20	2.00e-121	429.00
IUUC-Sly-110964	Solanum lycopersicum	40.22	7.00e-126	444.00
IUUC-Stu-112882	Solanum tuberosum	40.22	5.00e-126	444.00
IUUC-Sar-113230	Sorex araneus	71.06	0.00e+00	771.00
IUUC-Sbi-113962	Sorghum bicolor	36.28	3.00e-116	412.00
IUUC-Ssc-115987	Sus scrofa	98.96	2.00e-160	558.00
IUUC-Tgu-116471	Taeniopygia guttata	98.27	0.00e+00	1152.00
IUUC-Tru-118231	Takifugu rubripes	86.70	0.00e+00	980.00
IUUC-Tsy-119415	Tarsius syrichta	98.27	0.00e+00	1134.00
IUUC-Tni-120893	Tetraodon nigroviridis	86.87	0.00e+00	988.00
IUUC-Tca-121703	Theobroma cacao	40.26	2.00e-123	436.00
IUUC-Tae-125317	Triticum aestivum	40.51	5.00e-127	448.00
IUUC-Tur-126557	Triticum urartu	40.19	4.00e-124	438.00
IUUC-Tbe-127253	Tupaia belangeri	69.15	0.00e+00	763.00
IUUC-Ttr-129100	Tursiops truncatus	97.89	0.00e+00	1105.00
IUUC-Vpa-130613	Vicugna pacos	92.03	0.00e+00	1058.00
IUUC-Vvi-130880	Vitis vinifera	40.54	3.00e-118	418.00
IUUC-Xtr-132033	Xenopus tropicalis	95.15	0.00e+00	1147.00
IUUC-Xma-133421	Xiphophorus maculatus	86.16	0.00e+00	992.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence