iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028022

UUCD1 version

UUC-DaR-01387

Ensembl Protein ID

ENSDARP00000102515.3

UniProt Accession

E9QF30; X1WHW2; E9QF30_DANRE

Genbank Protein ID

ENSDARP00000102515

Protein Name

Si:dkey-82j4.2

Genbank Nucleotide ID

BX511083

Gene Name

UBA6; si:dkey-82j4.2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000080019.5	ENSDART00000111454.4	ENSDARP00000102515.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.90e-185	617.9	411	900

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv......gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealke 83
           YD +++++G+  + kl +++v++vG+g++GcE+lKnL+l+Gv      g+i+++D d +e+snlnrqFLfr+++++k+K+ +aaea  e
   Q: 411  YDALRACIGQSLCLKLHKFQVFMVGCGAIGCEMLKNLALLGVglsrflGEICITDPDLIEKSNLNRQFLFRPHHIQKPKSTTAAEASLE 499
           9**************************************************************************************** PP
   S: 84   lnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqk 169
           +np  ++ ah  ++++ +e+i+   Ff++++vVv+aldn+earr+v+++ +++++ l++sgt+G++G++++i++ lte+y++++dpp++
   Q: 500  INPELQIHAHLHKVCPATEDIYsddFFSRLNVVVTALDNVEARRYVDSRSVSNQKALLDSGTMGTKGHTEIIVPNLTESYNSHRDPPEE 588
           ***************************************************************************************** PP
   S: 170  tiPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafa 246
           +iPfctlk++p++ ehti+wa            ++ n++++ ++++++vl+++   e+ eg ++v  +l s+++ +++ +i++a+ +f+
   Q: 589  EIPFCTLKSFPAVTEHTIQWArdkfesafahkpSMYNMFWQSHSSAQSVLQRMMGGESMEGSFQV-IKLLSRRPTQWDHCITLARLKFD 676
           *****************************************************************.999******************** PP
   S: 247  kttinsikqllksfecdivtkskspfwv.........................................................sfcs 278
           k+++ ++ qll+sf+ d + k++s fw+                                                         ++++
   Q: 677  KYFKRKALQLLHSFPLDTRLKDGSLFWQspkrppspidfdlsdplhfgfvvsaarlfagiynipyseeqlsyedvsrvlaevdvpEYKP 765
           *************************************************************************************9999 PP
   S: 279  naealqvpekvekdeevvkasap......lylllraler.fekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddli 358
            ++ ++++e+v+k+ + +   ++      ++ l +a+++ + + + + ++ l fekddd   ++d+v++a++lra +++ie+ +d+ ++
   Q: 766  AEKHIETDETVKKPDQLKITVSSeeereaISQLQEAINSnLVTPERLCMSPLFFEKDDDTngHMDFVASASALRARMYAIEA-ADRLQT 853
           99999999888887665433322355788666666665405555566788999*****************************.****** PP
   S: 359  keiagniipaiattnavvgGlaaqEviKvvsg.kfeplknfflfdae 404
           k+iag+iipaiat +a+v+Gl+++E+iK++ g  fe +kn+f+++a+
   Q: 854  KRIAGKIIPAIATSTAAVAGLVSMELIKIAGGyGFELFKNCFFNLAI 900
           ********************************99*********9876 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MADSMDIDDS LYSRQRYVLG DSAMHQMAQS TVFVSGMGAL GVEIAKNIVL AGVKAVTLHD 60
SKRCEVWDLG TNFFIREEDV NNQKKRVEAV HSRVAELNPY VQVTMSTDVL DESTDLSFLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAAGAAGTG TGCAGCTCCC GATCCTCGCG CACATTGACA GGTAGCTAAT TCACTGCTCT 60
CTTTCTGCAC TTCAGACATT ACTTTATACC TCGACTGGCT GAAAACAAGC CATCGCCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR000011--UBQ/SUMO-activ_enz_E1-like

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

KEGG

dre:567370

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001608	Ailuropoda melanoleuca	66.90	0.00e+00	1479.00
IUUC-Apl-004158	Anas platyrhynchos	68.50	0.00e+00	1456.00
IUUC-Aca-005349	Anolis carolinensis	67.94	0.00e+00	1504.00
IUUC-Bta-012696	Bos taurus	66.76	0.00e+00	1467.00
IUUC-Cja-019563	Callithrix jacchus	66.54	0.00e+00	1436.00
IUUC-Cfa-020951	Canis familiaris	67.09	0.00e+00	1486.00
IUUC-Cpo-022307	Cavia porcellus	65.78	0.00e+00	1428.00
IUUC-Csa-023647	Chlorocebus sabaeus	66.54	0.00e+00	1448.00
IUUC-Cho-024682	Choloepus hoffmanni	53.70	0.00e+00	637.00
IUUC-Dno-029796	Dasypus novemcinctus	66.41	0.00e+00	1450.00
IUUC-Dor-030981	Dipodomys ordii	57.06	0.00e+00	1155.00
IUUC-Ete-032514	Echinops telfairi	58.45	0.00e+00	859.00
IUUC-Eca-033697	Equus caballus	67.55	0.00e+00	1485.00
IUUC-Eeu-035323	Erinaceus europaeus	61.86	0.00e+00	974.00
IUUC-Fca-035858	Felis catus	67.09	0.00e+00	1478.00
IUUC-Fal-036848	Ficedula albicollis	67.94	0.00e+00	1462.00
IUUC-Gmo-039326	Gadus morhua	77.18	0.00e+00	1619.00
IUUC-Gga-040747	Gallus gallus	68.33	0.00e+00	1453.00
IUUC-Gac-041406	Gasterosteus aculeatus	76.34	0.00e+00	1589.00
IUUC-Ggo-044577	Gorilla gorilla	66.47	0.00e+00	1442.00
IUUC-Hsa-046007	Homo sapiens	66.73	0.00e+00	1436.00
IUUC-Itr-048191	Ictidomys tridecemlineatus	69.03	0.00e+00	818.00
IUUC-Lch-049992	Latimeria chalumnae	68.30	0.00e+00	1442.00
IUUC-Loc-051899	Lepisosteus oculatus	73.82	0.00e+00	1608.00
IUUC-Laf-054413	Loxodonta africana	66.26	0.00e+00	1380.00
IUUC-Mcc-054656	Macaca mulatta	66.54	0.00e+00	1445.00
IUUC-Meu-056463	Macropus eugenii	57.16	0.00e+00	1113.00
IUUC-Mga-059721	Meleagris gallopavo	67.28	0.00e+00	1355.00
IUUC-Mmr-060908	Microcebus murinus	64.90	0.00e+00	1402.00
IUUC-Mdo-062096	Monodelphis domestica	67.94	0.00e+00	1483.00
IUUC-Mmu-064114	Mus musculus	68.11	0.00e+00	1489.00
IUUC-Mpu-066017	Mustela putorius furo	66.60	0.00e+00	1472.00
IUUC-Mlu-068037	Myotis lucifugus	65.79	0.00e+00	1412.00
IUUC-Nle-069494	Nomascus leucogenys	66.83	0.00e+00	1440.00
IUUC-Ont-071592	Oreochromis niloticus	78.06	0.00e+00	1654.00
IUUC-Oan-073268	Ornithorhynchus anatinus	64.48	0.00e+00	1261.00
IUUC-Ocu-074296	Oryctolagus cuniculus	67.68	0.00e+00	1488.00
IUUC-Ola-086376	Oryzias latipes	76.81	0.00e+00	1575.00
IUUC-Oga-088186	Otolemur garnettii	66.57	0.00e+00	1447.00
IUUC-Oar-089307	Ovis aries	67.06	0.00e+00	1471.00
IUUC-Ptr-090609	Pan troglodytes	66.73	0.00e+00	1438.00
IUUC-Pan-092905	Papio anubis	65.98	0.00e+00	1363.00
IUUC-Psi-093489	Pelodiscus sinensis	68.01	0.00e+00	1451.00
IUUC-Pma-094203	Petromyzon marinus	67.13	3.00e-56	210.00
IUUC-Pfo-096670	Poecilia formosa	76.42	0.00e+00	1618.00
IUUC-Pab-098418	Pongo abelii	66.54	0.00e+00	1434.00
IUUC-Pca-100889	Procavia capensis	56.76	0.00e+00	1169.00
IUUC-Pva-103144	Pteropus vampyrus	58.55	0.00e+00	1241.00
IUUC-Rno-105612	Rattus norvegicus	67.94	0.00e+00	1493.00
IUUC-Sha-107388	Sarcophilus harrisii	68.50	0.00e+00	1482.00
IUUC-Sar-113128	Sorex araneus	67.91	0.00e+00	1466.00
IUUC-Ssc-116117	Sus scrofa	66.70	0.00e+00	1463.00
IUUC-Tgu-116565	Taeniopygia guttata	68.14	0.00e+00	1466.00
IUUC-Tru-118591	Takifugu rubripes	75.83	0.00e+00	1590.00
IUUC-Tsy-119436	Tarsius syrichta	58.87	0.00e+00	1239.00
IUUC-Tni-120880	Tetraodon nigroviridis	75.59	0.00e+00	1585.00
IUUC-Tbe-127714	Tupaia belangeri	52.75	0.00e+00	1081.00
IUUC-Ttr-129159	Tursiops truncatus	63.74	0.00e+00	1211.00
IUUC-Vpa-130716	Vicugna pacos	64.52	0.00e+00	1380.00
IUUC-Xtr-132947	Xenopus tropicalis	62.27	0.00e+00	1360.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence