iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059694

UUCD1 version

UUC-MeG-00514

Ensembl Protein ID

ENSMGAP00000011727.1

UniProt Accession

G1NFE8; G1NFE8_MELGA

Protein Name

Uncharacterized protein

Gene Name

STRN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000011215.1	ENSMGAT00000012608.1	ENSMGAP00000011727.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.30e-29	99.1	628	665
UBD/Beta-Prp	1.30e-44	152.3	542	702

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           H d vt+la  ++  +l sGs+D++i++W+l + ++++
   Q: 628  HLDAVTSLAVdPNgLYLMSGSHDCSIRLWNLESKTCIQ 665
           99*********77799***************9999987 PP

UBD/Beta-Prp

   S: 15   cvkf.spdksllatgsrdgtikvwdvttgkllrsl.sgheae......vtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghed 95
           +v+  s d sl+++++ +g + +++++t + + +l sg +++      ++ v  +p+ +i +t++eDr+ik +d +tgk +h++ +h d
   Q: 542  SVDLvSSDPSLMVASFNTGHTSIFNMETRQRILTLeSGVDNAvstscqINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVAHLD 630
           4555588999*********************9999555555566666666666677777****************************** PP
   S: 96   svlslsfspsgdklvsGshdrtirvwdletgqclee...tlsghdgvvncvvvhpdgnllvsGslDrtvrlW 164
            v+sl+++p+g +l sGshd  ir+w+le+++c++e     ++ d+++  v++hp++++++s+++D   +++
   Q: 631  AVTSLAVDPNGLYLMSGSHDCSIRLWNLESKTCIQEftaHRKKFDESIHDVAFHPSKCYIASAGADALAKVF 702
           ***********************************877666777889999****************988887 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

LQAQIAFLQG ERKGQENLKK DLVRRIKMLE YALKQERAKY HKLKYGTELN QGDMKPPNYD 60
SDEGNETEIQ PQQNSQLIWK QGRQLLRQYL QEVGYTDTIL DVKSKQVRAL LGLSSDASEK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGCAGGCCC AGATCGCTTT TCTTCAAGGT GAAAGGAAGG GGCAAGAAAA TCTGAAGAAG 60
GACCTAGTGC GGAGAATCAA AATGCTGGAA TATGCACTTA AACAAGAAAG GTACGTTGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08232--Striatin
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005923--C:bicellular tight junction
GO:0000159--C:protein phosphatase type 2A complex
GO:0008285--P:negative regulation of cell proliferation
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001899	Ailuropoda melanoleuca	87.78	0.00e+00	1183.00
IUUC-Apl-003927	Anas platyrhynchos	97.44	0.00e+00	1220.00
IUUC-Aca-004933	Anolis carolinensis	84.04	0.00e+00	1175.00
IUUC-Ame-010997	Astyanax mexicanus	76.29	0.00e+00	989.00
IUUC-Bta-013077	Bos taurus	87.93	0.00e+00	1183.00
IUUC-Cja-018973	Callithrix jacchus	88.64	0.00e+00	1191.00
IUUC-Cfa-020988	Canis familiaris	84.78	0.00e+00	1132.00
IUUC-Cpo-022496	Cavia porcellus	88.07	0.00e+00	1201.00
IUUC-Csa-023829	Chlorocebus sabaeus	88.35	0.00e+00	1189.00
IUUC-Cho-024338	Choloepus hoffmanni	61.50	0.00e+00	779.00
IUUC-Cin-025167	Ciona intestinalis	46.35	2.00e-162	565.00
IUUC-Csv-026143	Ciona savignyi	49.38	5.00e-169	587.00
IUUC-Dre-028560	Danio rerio	70.85	0.00e+00	902.00
IUUC-Dno-029742	Dasypus novemcinctus	82.81	0.00e+00	1129.00
IUUC-Dor-030721	Dipodomys ordii	79.55	0.00e+00	1060.00
IUUC-Ete-032770	Echinops telfairi	55.98	0.00e+00	712.00
IUUC-Eca-033760	Equus caballus	88.05	0.00e+00	1181.00
IUUC-Eeu-034953	Erinaceus europaeus	89.32	0.00e+00	705.00
IUUC-Fca-036530	Felis catus	87.48	0.00e+00	1184.00
IUUC-Fal-037353	Ficedula albicollis	90.25	0.00e+00	961.00
IUUC-Gmo-039094	Gadus morhua	72.98	2.00e-179	622.00
IUUC-Gga-040132	Gallus gallus	99.57	0.00e+00	1233.00
IUUC-Gac-041713	Gasterosteus aculeatus	75.24	0.00e+00	985.00
IUUC-Ggo-045455	Gorilla gorilla	78.11	0.00e+00	996.00
IUUC-Hsa-046415	Homo sapiens	87.93	0.00e+00	1185.00
IUUC-Lch-050475	Latimeria chalumnae	84.14	0.00e+00	1118.00
IUUC-Loc-051859	Lepisosteus oculatus	79.41	0.00e+00	1066.00
IUUC-Laf-053537	Loxodonta africana	88.35	0.00e+00	1207.00
IUUC-Mcc-055817	Macaca mulatta	88.35	0.00e+00	1189.00
IUUC-Meu-055946	Macropus eugenii	65.29	0.00e+00	765.00
IUUC-Mla-058988	Melampsora laricipopulina	35.33	3.00e-64	239.00
IUUC-Mmr-060768	Microcebus murinus	88.78	0.00e+00	1196.00
IUUC-Mdo-061901	Monodelphis domestica	84.04	0.00e+00	1164.00
IUUC-Mmu-064154	Mus musculus	86.79	0.00e+00	1175.00
IUUC-Mpu-065827	Mustela putorius furo	82.54	0.00e+00	1172.00
IUUC-Mlu-067102	Myotis lucifugus	88.21	0.00e+00	1189.00
IUUC-Ncr-068831	Neurospora crassa	39.60	3.00e-22	100.00
IUUC-Nle-070008	Nomascus leucogenys	88.19	0.00e+00	1186.00
IUUC-Opr-071067	Ochotona princeps	55.84	5.00e-149	520.00
IUUC-Ont-072025	Oreochromis niloticus	75.35	0.00e+00	977.00
IUUC-Oan-072950	Ornithorhynchus anatinus	88.77	0.00e+00	1136.00
IUUC-Ocu-074316	Oryctolagus cuniculus	87.48	0.00e+00	1172.00
IUUC-Ola-087279	Oryzias latipes	73.09	0.00e+00	942.00
IUUC-Oga-088284	Otolemur garnettii	88.07	0.00e+00	1192.00
IUUC-Oar-090304	Ovis aries	88.07	0.00e+00	1187.00
IUUC-Ptr-091052	Pan troglodytes	88.07	0.00e+00	1186.00
IUUC-Pan-092270	Papio anubis	85.13	0.00e+00	1154.00
IUUC-Psi-093907	Pelodiscus sinensis	91.29	0.00e+00	1072.00
IUUC-Pma-094286	Petromyzon marinus	66.07	0.00e+00	632.00
IUUC-Pfo-097042	Poecilia formosa	74.55	0.00e+00	1048.00
IUUC-Pab-098110	Pongo abelii	88.07	0.00e+00	1186.00
IUUC-Pca-100266	Procavia capensis	75.00	0.00e+00	817.00
IUUC-Pva-102824	Pteropus vampyrus	86.79	0.00e+00	1149.00
IUUC-Pgr-103483	Puccinia graminis	38.15	4.00e-57	216.00
IUUC-Ptt-103828	Puccinia triticina	37.35	3.00e-47	183.00
IUUC-Rno-105638	Rattus norvegicus	87.36	0.00e+00	1184.00
IUUC-Sha-107004	Sarcophilus harrisii	84.02	0.00e+00	1080.00
IUUC-Ssc-115280	Sus scrofa	88.21	0.00e+00	1192.00
IUUC-Tgu-116759	Taeniopygia guttata	96.59	0.00e+00	1226.00
IUUC-Tru-117944	Takifugu rubripes	75.91	0.00e+00	983.00
IUUC-Tsy-119405	Tarsius syrichta	77.64	0.00e+00	989.00
IUUC-Tni-120571	Tetraodon nigroviridis	75.00	0.00e+00	987.00
IUUC-Tre-122113	Trichoderma reesei	43.56	5.00e-24	106.00
IUUC-Ttr-128600	Tursiops truncatus	63.60	0.00e+00	831.00
IUUC-Uma-129659	Ustilago maydis	34.70	2.00e-64	239.00
IUUC-Vda-129673	Verticillium dahliae	38.55	6.00e-18	85.90
IUUC-Vpa-130294	Vicugna pacos	87.89	0.00e+00	1173.00
IUUC-Xtr-132330	Xenopus tropicalis	62.22	0.00e+00	856.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence