iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011822

Ensembl Protein ID

ENSAMXP00000005885.1

UniProt Accession

W5KE74; W5KE74_ASTMX

Genbank Protein ID

ENSAMXP00000005885

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01076729

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000005725.1	ENSAMXT00000005885.1	ENSAMXP00000005885.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.30e-39	130.3	1638	1668
UBD/Beta-Prp	9.30e-69	232.1	1476	1709

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH++sv++++f ++  ll+sGs Dg + +W+
   Q: 1638 GHQSSVRSVSFsPSsSLLCSGSLDGEVLLWS 1668
           8***********6669**************8 PP

UBD/Beta-Prp

   S: 12   vitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvl 98
             +cv+ sp++  +a+g ++gti    ++t + ++sl ++ ++++++ f +dg +l t+s D+ + vwd+++g+ +++l++h+++++
   Q: 1476 KPSCVALSPGGGCVAVGTEQGTIHFIHTHTNQEVKSLVSNCDGISSCVFLDDG-FLSTTSYDGQVEVWDINSGSRTVHLNAHSNRIT 1561
           5679*******************87777777888***99999**********9.********************************* PP
   S: 99   slsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvys 185
            +++s +++++++ s d+ ++vw  ++g+ + ++l++     ncv+++p+g ll+ G+ Drtvr+W+   ++  +tl+g h++sv+s
   Q: 1562 GCDVSSDKKHFATVSLDSNLKVWSSQKGKQVVSLLTPCP--LNCVTFDPEGGLLAVGCWDRTVRVWNWIKQERWTTLSG-HQSSVRS 1645
           *******************************99999988..*************************************9.******* PP
   S: 186  lsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           +sf++++  l sgsldg v lw+ +   cv ++++h+  +  + f++ +e l+s+++Dg +++W
   Q: 1646 VSFSPSSSLLCSGSLDGEVLLWSSSGLACVGRYQAHRGSTEALSFLSGGEALLSAGHDGMVQLW 1709
           **************************************************************** PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MDSGHTELPV LDLRLSDEEE KQTVDVGEVF TVSSTDSDWT VELLKEKKYV LLNVVCCSLV 60
NKSSAPNQND WDSKENVWTR IKDLGTQITR RDPEFILKVA VYTRQELNIR ITTNFLLALA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCATATTGT AGTAATTACG GTATTGACTC AGCTCAGCTG GTAAAAGTTG TTATTCAGGA 60
AGCAGGGATT CTCCTATAAA CCAGTGATCA CTGATCAGTC CGGACTGGAA ACGGATCAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR025139--DUF4062
IPR027417--P-loop_NTPase
IPR008858--TROVE_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50988--TROVE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF05731--TROVE
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0003723--F:RNA binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-012323	Bos taurus	33.23	0.00e+00	673.00
IUUC-Cpo-022312	Cavia porcellus	34.03	0.00e+00	852.00
IUUC-Csa-023287	Chlorocebus sabaeus	33.98	0.00e+00	861.00
IUUC-Dre-028825	Danio rerio	54.52	0.00e+00	1923.00
IUUC-Dor-030328	Dipodomys ordii	33.15	2.00e-164	574.00
IUUC-Ete-032385	Echinops telfairi	36.40	2.00e-112	401.00
IUUC-Eca-033726	Equus caballus	34.88	0.00e+00	890.00
IUUC-Eeu-034665	Erinaceus europaeus	45.19	2.00e-70	262.00
IUUC-Gmo-039584	Gadus morhua	49.78	0.00e+00	741.00
IUUC-Gac-042307	Gasterosteus aculeatus	47.28	0.00e+00	1485.00
IUUC-Itr-049021	Ictidomys tridecemlineatus	34.34	0.00e+00	901.00
IUUC-Lch-050186	Latimeria chalumnae	39.67	1.00e-68	253.00
IUUC-Laf-054524	Loxodonta africana	34.20	0.00e+00	655.00
IUUC-Mcc-055628	Macaca mulatta	34.14	0.00e+00	889.00
IUUC-Mmu-064406	Mus musculus	33.62	0.00e+00	822.00
IUUC-Mpu-065806	Mustela putorius furo	34.66	0.00e+00	650.00
IUUC-Mlu-068116	Myotis lucifugus	35.20	2.00e-120	428.00
IUUC-Opr-070242	Ochotona princeps	34.28	8.00e-168	585.00
IUUC-Oan-073598	Ornithorhynchus anatinus	33.27	2.00e-123	437.00
IUUC-Ola-086886	Oryzias latipes	50.54	0.00e+00	1590.00
IUUC-Oga-088609	Otolemur garnettii	33.59	0.00e+00	862.00
IUUC-Oar-089957	Ovis aries	35.06	6.00e-179	622.00
IUUC-Pan-092397	Papio anubis	34.26	0.00e+00	883.00
IUUC-Pma-094373	Petromyzon marinus	31.62	5.00e-36	145.00
IUUC-Pca-101002	Procavia capensis	34.93	5.00e-170	593.00
IUUC-Pva-102144	Pteropus vampyrus	38.13	1.00e-77	286.00
IUUC-Rno-105828	Rattus norvegicus	33.54	0.00e+00	841.00
IUUC-Sar-113035	Sorex araneus	34.31	6.00e-124	440.00
IUUC-Ssc-116122	Sus scrofa	32.53	0.00e+00	630.00
IUUC-Tru-118412	Takifugu rubripes	49.02	0.00e+00	1606.00
IUUC-Tsy-119257	Tarsius syrichta	35.96	1.00e-50	196.00
IUUC-Tni-120032	Tetraodon nigroviridis	49.69	1.00e-77	283.00
IUUC-Tbe-127312	Tupaia belangeri	43.18	1.00e-75	279.00
IUUC-Ttr-128335	Tursiops truncatus	34.93	0.00e+00	640.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence