iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062445

Ensembl Protein ID

ENSMODP00000016879.3

UniProt Accession

F7F8R2; F7F8R2_MONDO

Protein Name

Non-specific serine/threonine protein kinase

Gene Name

MARK3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000013489.3	ENSMODT00000017192.3	ENSMODP00000016879.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	83.33	0.00e+00	1311.00	IUUC-Hsa-046881

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MSTRTPLPTV IERDTENHTS HGDGRQEVTS RTGRSGARCR NSVASCADEQ PHIGNYRLLK 60
TIGKGNFAKV KLARHILTGR EVAIKIIDKT QLNPTSLQKL FREVRIMKIL NHPNIVKLFE 120

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Nucleotide Sequence
(Fasta)

GTCTGGGGTC GGCGAGGGGA GCCGGAGGCA GCAGAGGAAG CTGGGCGGCG GCCATCTTGG 60
ATCTCTGAGG AGAGGCGGCA GCAGGCTGCG GAGATTTGGG CAGCGGAGGC AGGCAGGGAG 120

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Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR028375--KA1/Ssp2_C
IPR001772--KA1_dom
IPR011009--Kinase-like_dom
IPR033624--MARK/par1
IPR033628--MARK3
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA

PROSITE

PS50032--KA1
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF02149--KA1
PF00069--Pkinase
PF00627--UBA

SMART

SM00220--S_TKc
SM00165--UBA

Gene Ontology

GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0030010--P:establishment of cell polarity
GO:0000226--P:microtubule cytoskeleton organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004735	Anolis carolinensis	87.15	0.00e+00	1407.00
IUUC-Cel-018198	Caenorhabditis elegans	73.24	3.00e-161	562.00
IUUC-Cfa-020081	Canis familiaris	82.35	0.00e+00	1233.00
IUUC-Cpo-022503	Cavia porcellus	85.35	0.00e+00	1351.00
IUUC-Cgl-026480	Colletotrichum gloeosporioides	41.06	4.00e-69	256.00
IUUC-Dre-028387	Danio rerio	79.69	0.00e+00	1231.00
IUUC-Dno-029052	Dasypus novemcinctus	85.59	0.00e+00	1338.00
IUUC-Eca-033300	Equus caballus	86.76	0.00e+00	1347.00
IUUC-Fca-036517	Felis catus	87.25	0.00e+00	1339.00
IUUC-Fal-037115	Ficedula albicollis	92.77	0.00e+00	1316.00
IUUC-Gmo-039460	Gadus morhua	57.29	0.00e+00	771.00
IUUC-Gga-040502	Gallus gallus	91.64	0.00e+00	1489.00
IUUC-Ggo-044770	Gorilla gorilla	67.91	0.00e+00	692.00
IUUC-Hsa-046881	Homo sapiens	86.30	0.00e+00	1372.00
IUUC-Lch-049922	Latimeria chalumnae	83.41	0.00e+00	1284.00
IUUC-Loc-052896	Lepisosteus oculatus	82.61	0.00e+00	1275.00
IUUC-Laf-054590	Loxodonta africana	84.65	0.00e+00	1288.00
IUUC-Mcc-054721	Macaca mulatta	86.42	0.00e+00	1373.00
IUUC-Mmr-060647	Microcebus murinus	85.82	0.00e+00	1335.00
IUUC-Mpu-066504	Mustela putorius furo	82.84	0.00e+00	1271.00
IUUC-Ont-072503	Oreochromis niloticus	73.64	0.00e+00	1181.00
IUUC-Oan-072929	Ornithorhynchus anatinus	86.50	0.00e+00	1325.00
IUUC-Ocu-073853	Oryctolagus cuniculus	85.45	0.00e+00	1363.00
IUUC-Ola-086790	Oryzias latipes	56.42	0.00e+00	823.00
IUUC-Oar-090325	Ovis aries	84.63	0.00e+00	1332.00
IUUC-Pan-092891	Papio anubis	93.82	0.00e+00	1529.00
IUUC-Psi-092994	Pelodiscus sinensis	86.79	0.00e+00	1338.00
IUUC-Pca-100880	Procavia capensis	75.66	0.00e+00	887.00
IUUC-Pgr-103687	Puccinia graminis	44.88	2.00e-70	260.00
IUUC-Ptt-103944	Puccinia triticina	44.73	1.00e-66	248.00
IUUC-Sha-107115	Sarcophilus harrisii	89.21	0.00e+00	1414.00
IUUC-Tru-118387	Takifugu rubripes	70.25	0.00e+00	1097.00
IUUC-Tme-127019	Tuber melanosporum	44.65	2.00e-69	257.00
IUUC-Xtr-132367	Xenopus tropicalis	58.88	0.00e+00	669.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence