iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000017099.3	ENSXETT00000011899.3	ENSXETP00000011899.3
ENSXETG00000017099.3	ENSXETT00000037279.3	ENSXETP00000037279.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.90e-27	92.1	1273	1307
UBD/Beta-Prp	1.30e-40	139.6	1379	1579

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           gHt +v c++ +d ll +Gs D t+k+W+l tg  
   Q: 1273 GHTKPVLCVEATDELLFTGSKDRTCKLWNLVTGQE 1307
           8********9878*****************99975 PP

UBD/Beta-Prp

   S: 52   eaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqclee.... 131
           e ++++++++pdg +++ ++  ++++ wdls ++++ +l+gh + v++l++s   +g d +++Gs+d ++++++l++g+        
   Q: 1379 ELQINQITLNPDG-TILYAAAGNAVRAWDLSRFQPIGKLTGHMAPVMCLTVSNtqNGrDLVITGSKDHYVKIFELHSGWGGAVppty 1464
           55699*******9.9999*******************************999988888*********************88778888 PP
   S: 132  .tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrt 217
            ++ +h + + c++v+    +l sGs D+ ++ Wdl++ +l ++   +h d +  l f + +  l+sg + g +k+w++++ + + +
   Q: 1465 nLEPPHYDGIECLAVQN--GILCSGSRDNGIKKWDLQQHELTQQVPNAHRDWICALGFVPGRSMLLSGCRGGILKVWNMENFTPIGE 1549
           8999***********99..**************************999*************************************** PP
   S: 218  lnghtdnvksvrfspnderlvsgssDgsiriW 249
            +gh+++++  ++++n+ ++ ++ssD  +++W
   Q: 1550 IKGHESPIN--AMCSNSRHIFTASSDCRVKLW 1579
           *********..66778***************9 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

AMGSQGDCSV RVALRIRPQS SKEQTEGCRI CTWVYAGEPQ VLLGKDKAFT YDFVFDMDTD 60
QIQVYETCVR GLVEGCFQGY NATVLAYGQT GAGKTHTMGS GFDLVVTEEE LGIIPRAVRQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGAGTGCT GGGAGTTGGT GCATGATGTG AAATATCCAC CCTTGCCTTG AGATGAAAAA 60
TCTGCCCCTG ATACCTCCTG CCCCACCTGA AATTCCCAGG GCAGTGAGGA ATAAGAAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005871--C:kinesin complex
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	64.83	0.00e+00	1120.00
IUUC-Aca-004506	Anolis carolinensis	62.48	0.00e+00	1120.00
IUUC-Ame-011515	Astyanax mexicanus	59.19	0.00e+00	1757.00
IUUC-Cja-018844	Callithrix jacchus	65.43	0.00e+00	1127.00
IUUC-Cpo-022444	Cavia porcellus	64.28	0.00e+00	1805.00
IUUC-Csv-026158	Ciona savignyi	40.39	0.00e+00	714.00
IUUC-Dre-027839	Danio rerio	62.49	0.00e+00	1146.00
IUUC-Dno-030058	Dasypus novemcinctus	63.21	0.00e+00	1793.00
IUUC-Dor-030673	Dipodomys ordii	65.73	0.00e+00	1125.00
IUUC-Fca-035388	Felis catus	65.13	0.00e+00	1129.00
IUUC-Fal-037044	Ficedula albicollis	64.73	0.00e+00	1197.00
IUUC-Gac-041328	Gasterosteus aculeatus	59.55	0.00e+00	1112.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	64.18	0.00e+00	1032.00
IUUC-Lch-049786	Latimeria chalumnae	62.55	0.00e+00	1882.00
IUUC-Loc-052703	Lepisosteus oculatus	62.12	0.00e+00	1838.00
IUUC-Laf-054193	Loxodonta africana	59.94	0.00e+00	1042.00
IUUC-Mcc-055484	Macaca mulatta	64.53	0.00e+00	1137.00
IUUC-Meu-056278	Macropus eugenii	59.94	0.00e+00	772.00
IUUC-Mmr-061071	Microcebus murinus	63.34	0.00e+00	1798.00
IUUC-Mmu-063967	Mus musculus	65.07	0.00e+00	1107.00
IUUC-Opr-070325	Ochotona princeps	63.49	0.00e+00	1083.00
IUUC-Ont-071851	Oreochromis niloticus	59.87	0.00e+00	1807.00
IUUC-Oan-073615	Ornithorhynchus anatinus	65.97	0.00e+00	1175.00
IUUC-Ocu-073855	Oryctolagus cuniculus	65.40	0.00e+00	1126.00
IUUC-Ola-086703	Oryzias latipes	60.68	0.00e+00	1117.00
IUUC-Oga-088171	Otolemur garnettii	63.25	0.00e+00	1812.00
IUUC-Ptr-090535	Pan troglodytes	64.02	0.00e+00	1136.00
IUUC-Psi-093752	Pelodiscus sinensis	58.24	0.00e+00	1623.00
IUUC-Pab-098441	Pongo abelii	64.70	0.00e+00	1844.00
IUUC-Rno-105872	Rattus norvegicus	64.39	0.00e+00	1842.00
IUUC-Sha-107097	Sarcophilus harrisii	64.39	0.00e+00	1099.00
IUUC-Tru-118242	Takifugu rubripes	59.48	0.00e+00	1127.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence