iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000015704.2	ENSFCAT00000031906.1	ENSFCAP00000020866.1
ENSFCAG00000015704.2	ENSFCAT00000015708.2	ENSFCAP00000014564.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.20e-59	193.6	166	204
UBD/Beta-Prp	2.90e-92	309.0	122	326

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           H ++v+c +f +d +l+vs+sdD+t+k+WD ++  +++s
   Q: 166  HINWVRCARFsPDgRLIVSASDDKTVKLWDKTSRECVHS 204
           999********999******************9999886 PP

UBD/Beta-Prp

   S: 49   sgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghd 137
             h+a+v++v f +dg+ +vt+s+D+t+kvw+    k + +l++h + v++ +fsp+g  +vs+s+d+t+++wd  +++c++    +h 
   Q: 122  RAHTATVRSVHFCSDGQSFVTASDDKTVKVWSTHRQKFLFSLSQHINWVRCARFSPDGRLIVSASDDKTVKLWDKTSRECVH-SYCEHG 209
           57999****************************************************************************9.9999** PP
   S: 138  gvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvk 226
           g+v++v +hp+g ++++++ D+tv++Wd++t +ll++ +  h  +v+ lsf+++g++l+++s d+t+k+ dl +g+ ++tl+gh+ + +
   Q: 210  GFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQL-HSAAVNALSFHPSGNYLLTASSDSTLKILDLMEGRLLYTLHGHQGPAT 297
           **********99**************************98.************************************************ PP
   S: 227  svrfspnderlvsgssDgsiriW..dlrs 253
            v+fs+ +e+++sg+sD+++ +W  + + 
   Q: 298  TVAFSRTGEYFASGGSDEQVMVWksNFDV 326
           ***********************665444 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MRKAWREPCS EQRDFLWPTS SLVAPWFPED PSLERHFKGH RDAVTCVDFS LNTKQLASGS 60
MDSCLMIWHM KPQSRAYRFA GHKDAVTCVN FSPSGHLLAS GSRDKTVRIW IPNVKGESTV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCCACAGCT GCAGGGCTTT CCAGTACCCT GAGAAGTCAC TAGGTCTGCC CTATGCCCAA 60
ACTCGCCTTC AGGTTATCAG GAAGCTCAGT GCGACCAGCA TATCCTGGGT TCATGGTGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000922--C:spindle pole
GO:0003431--P:growth plate cartilage chondrocyte development
GO:0007052--P:mitotic spindle organization
GO:1905515--P:non-motile cilium assembly
GO:0010825--P:positive regulation of centrosome duplication
GO:0007283--P:spermatogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001513	Ailuropoda melanoleuca	97.76	0.00e+00	775.00
IUUC-Apl-003466	Anas platyrhynchos	79.25	0.00e+00	656.00
IUUC-Aca-004323	Anolis carolinensis	72.15	0.00e+00	632.00
IUUC-Bta-012484	Bos taurus	94.53	0.00e+00	794.00
IUUC-Cja-019067	Callithrix jacchus	88.28	0.00e+00	786.00
IUUC-Cfa-020439	Canis familiaris	97.01	0.00e+00	804.00
IUUC-Cpo-021403	Cavia porcellus	89.34	0.00e+00	786.00
IUUC-Cre-022724	Chlamydomonas reinhardtii	51.15	8.00e-114	403.00
IUUC-Csa-023479	Chlorocebus sabaeus	93.77	0.00e+00	699.00
IUUC-Cho-024354	Choloepus hoffmanni	87.73	6.00e-115	405.00
IUUC-Cin-025258	Ciona intestinalis	73.51	4.00e-142	498.00
IUUC-Csv-025955	Ciona savignyi	64.38	4.00e-147	514.00
IUUC-Dno-029467	Dasypus novemcinctus	79.43	7.00e-128	449.00
IUUC-Dor-030399	Dipodomys ordii	91.27	0.00e+00	768.00
IUUC-Dme-032182	Drosophila melanogaster	46.82	2.00e-80	292.00
IUUC-Eca-034425	Equus caballus	95.26	0.00e+00	760.00
IUUC-Eeu-034607	Erinaceus europaeus	82.34	0.00e+00	647.00
IUUC-Fal-037381	Ficedula albicollis	74.94	0.00e+00	635.00
IUUC-Gmo-038489	Gadus morhua	67.84	1.00e-161	562.00
IUUC-Gga-040559	Gallus gallus	75.25	0.00e+00	632.00
IUUC-Gac-041453	Gasterosteus aculeatus	68.92	2.00e-168	585.00
IUUC-Ggo-044773	Gorilla gorilla	94.51	0.00e+00	761.00
IUUC-Hsa-045823	Homo sapiens	95.26	0.00e+00	769.00
IUUC-Itr-048560	Ictidomys tridecemlineatus	93.77	0.00e+00	793.00
IUUC-Lch-050558	Latimeria chalumnae	67.50	1.00e-176	612.00
IUUC-Loc-052836	Lepisosteus oculatus	68.59	3.00e-177	614.00
IUUC-Laf-053974	Loxodonta africana	84.37	0.00e+00	677.00
IUUC-Mcc-055494	Macaca mulatta	90.80	0.00e+00	749.00
IUUC-Meu-056646	Macropus eugenii	75.69	3.00e-128	451.00
IUUC-Mga-059295	Meleagris gallopavo	68.85	8.00e-176	609.00
IUUC-Mmr-061040	Microcebus murinus	93.63	0.00e+00	793.00
IUUC-Mdo-062519	Monodelphis domestica	77.75	2.00e-178	617.00
IUUC-Mmu-063759	Mus musculus	94.33	1.00e-172	598.00
IUUC-Mpu-066442	Mustela putorius furo	97.01	0.00e+00	780.00
IUUC-Mlu-068163	Myotis lucifugus	90.52	0.00e+00	786.00
IUUC-Nle-070160	Nomascus leucogenys	94.01	0.00e+00	762.00
IUUC-Opr-070192	Ochotona princeps	90.86	0.00e+00	679.00
IUUC-Ont-072539	Oreochromis niloticus	71.56	1.00e-148	519.00
IUUC-Oan-072834	Ornithorhynchus anatinus	61.59	2.00e-112	398.00
IUUC-Ocu-074624	Oryctolagus cuniculus	93.22	0.00e+00	725.00
IUUC-Ola-087268	Oryzias latipes	61.94	4.00e-159	554.00
IUUC-Oga-088964	Otolemur garnettii	86.88	0.00e+00	735.00
IUUC-Oar-090202	Ovis aries	95.01	0.00e+00	757.00
IUUC-Ptr-091164	Pan troglodytes	95.26	0.00e+00	769.00
IUUC-Pan-092805	Papio anubis	93.22	0.00e+00	694.00
IUUC-Psi-093359	Pelodiscus sinensis	79.41	1.00e-163	569.00
IUUC-Pma-094425	Petromyzon marinus	75.86	9.00e-152	529.00
IUUC-Ppa-095677	Physcomitrella patens	46.38	1.00e-81	295.00
IUUC-Pfo-096741	Poecilia formosa	58.77	1.00e-154	539.00
IUUC-Pab-098376	Pongo abelii	94.76	0.00e+00	802.00
IUUC-Pca-101122	Procavia capensis	89.80	0.00e+00	756.00
IUUC-Pva-103104	Pteropus vampyrus	73.04	5.00e-167	580.00
IUUC-Rno-105282	Rattus norvegicus	87.57	0.00e+00	664.00
IUUC-Sha-106840	Sarcophilus harrisii	81.93	4.00e-118	417.00
IUUC-Smo-108731	Selaginella moellendorffii	45.28	2.00e-78	285.00
IUUC-Sar-113262	Sorex araneus	65.67	3.00e-146	511.00
IUUC-Ssc-115392	Sus scrofa	93.64	0.00e+00	654.00
IUUC-Tgu-117340	Taeniopygia guttata	74.50	9.00e-178	615.00
IUUC-Tru-117577	Takifugu rubripes	72.64	1.00e-135	476.00
IUUC-Tsy-119404	Tarsius syrichta	86.03	0.00e+00	718.00
IUUC-Tni-120713	Tetraodon nigroviridis	69.91	3.00e-136	478.00
IUUC-Tbe-127788	Tupaia belangeri	73.12	6.00e-157	546.00
IUUC-Ttr-128608	Tursiops truncatus	88.48	0.00e+00	721.00
IUUC-Xtr-132720	Xenopus tropicalis	63.06	5.00e-161	560.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence