iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118674

UUCD1 version

UUC-TaR-01139

Ensembl Protein ID

ENSTRUP00000020544.1

UniProt Accession

H2T7A5; H2T7A5_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000008211.1	ENSTRUT00000020629.1	ENSTRUP00000020544.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.60e-89	299.6	9	642

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenp.........kepkgellkslqklfeelw..kskkkavsprellkalk 78
           GlkN+gNtC+mN+v+QcLsn++ l+e+l   ++k++l ++            + kge++++l++l+++lw  +++ +     +++ +++
   Q: 9    GLKNHGNTCFMNAVVQCLSNTNVLAEYLGLkRYKHDLVQTGLngvlisdgtRHVKGEVTEQLATLVRALWtlEYTPQLSVDFKFKLIVS 97
           9**************************96645666665544477888887788899**************9988888999999****** PP
   S: 79   keaeefsgyeqqDaqEflaflldqleeelkk.eknkpkeeeeeedkselsde..aeekkkkknkslisdlFqgqlksqikclecdnvss 164
           k+ ++f+g++q+Da Efl +lld+++e+++   +n+++++ ++e++++  ++    +  +   +s++++ Fq q+ks+++c++c+++s+
   Q: 98   KYGSQFRGNSQHDALEFLLWLLDRVHEDVNPaTQNNNTMNVFGEATKKIGNNvnPASILPLGRHSFVKEHFQAQYKSSLTCPHCRKQSN 186
           *****************************77666667777766665544444214444566778************************* PP
   S: 165  reepfldlslpvpgkeetkke.................................................................... 185
           +++pfl +slp+p  +++ +                                                                     
   Q: 187  TFDPFLCISLPIPLCQTRLLHvilvfsnkgqrylrvkvavplfgsvaclrrmvadegklspdqviltevyskgfcrsffdeedlasiae 275
           *************999887779******************************************************************* PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 276  hdviyafqapaiyirggsarisgglpsspystgpmgqrllpsgtlssdflnqgvsvkilllvcnaagagqhvvrfgppflmredrsisw 364
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 365  dqlqqsilsklyylmlsgtqaqntgvlfnirvvgglgfynylspedklplyhpavegalkrcgpggpphvkliiewehrikdclfgniq 453
           ***************************************************************************************** PP
   S: 186  ......................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkk 252
                                 +l++c+  +tkee+l  +++++c++ck++ +   k++l++lP++LilhLkRf   +++++r+k+++ 
   Q: 454  eevvkdaenvrnqhqyihqyscTLDECFYLYTKEEQLAPDDAWKCPHCKQLEQGMVKMSLWTLPDILILHLKRF--MQDGEHRTKLTTF 540
           **************************************************************************..88889******** PP
   S: 253  vefple.Ldlspfctspeekqke.................kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeev 322
           v+fpl+ Ld++p++++ + +++                  +  Y+L+av++H+G++++GHY+a+++n  +g+W+ +dDs+ ++v+e+ev
   Q: 541  VHFPLNgLDMAPHMVNHNHGVHPppltswkqcqrrelippEFLYDLYAVCNHHGGMHGGHYTAFCRNsVDGQWYSYDDSSAEAVPEAEV 629
           ****************88888779999999999999***9***************************55777***************** PP
   S: 323  leetgstaYvlfYkrr 338
           ++   + aY+lfY+rr
   Q: 630  CT---RGAYILFYQRR 642
           **...*********96 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

GDQVPGVMGL KNHGNTCFMN AVVQCLSNTN VLAEYLGLKR YKHDLVQTGL NGVLISDGTR 60
HVKGEVTEQL ATLVRALWTL EYTPQLSVDF KFKLIVSKYG SQFRGNSQHD ALEFLLWLLD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGACCAAG TTCCGGGTGT CATGGGACTC AAAAACCATG GCAACACCTG TTTCATGAAC 60
GCCGTGGTCC AGTGCTTGAG CAACACCAAC GTCCTGGCAG AGTACCTGGG TTTAAAGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Dme-032088	Drosophila melanogaster	33.73	7.00e-104	372.00
IUUC-Gac-042482	Gasterosteus aculeatus	74.35	0.00e+00	1024.00
IUUC-Ttr-128829	Tursiops truncatus	49.62	0.00e+00	652.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence