iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-002327

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01130202

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000016038.1	ENSAMET00000017628.1	ENSAMEP00000016932.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	83.87	3.00e-67	252.00	IUUC-Hsa-046547

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MPRKAGNVEE AEASAEEVGA EEVGPEEYGG EESGAEESGP EESDPEEPGA EEEMEAGQSR 60
PVLRSVNSCE PSQVIFCNRS PRVVLPVWLN FDGGEHSPGA GTHECLHSFK SHLWLFRDAG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCCGGA AGGCAGGGAA CGTGGAAGAG GCCGAGGCGA GTGCGGAGGA GGTGGGCGCC 60
GAGGAGGTGG GCCCTGAAGA GTACGGCGGG GAGGAGTCGG GCGCTGAGGA GTCCGGGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR002714--VHL
IPR024048--VHL_alpha_dom
IPR024053--VHL_beta_dom
IPR022772--VHL_tumour_suppress_b/a_dom

Pfam

PF01847--VHL
PF17211--VHL_C

Gene Ontology

GO:0005929--C:cilium
GO:0031462--C:Cul2-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0001525--P:angiogenesis
GO:0043534--P:blood vessel endothelial cell migration
GO:0061073--P:ciliary body morphogenesis
GO:0030198--P:extracellular matrix organization
GO:0048069--P:eye pigmentation
GO:0048877--P:homeostasis of number of retina cells
GO:0061072--P:iris morphogenesis
GO:0006582--P:melanin metabolic process
GO:0045602--P:negative regulation of endothelial cell differentiation
GO:0010629--P:negative regulation of gene expression
GO:1902072--P:negative regulation of hypoxia-inducible factor-1alpha signaling pathway
GO:0070244--P:negative regulation of thymocyte apoptotic process
GO:0006607--P:NLS-bearing protein import into nucleus
GO:0003310--P:pancreatic A cell differentiation
GO:0050679--P:positive regulation of epithelial cell proliferation
GO:0010498--P:proteasomal protein catabolic process
GO:2001233--P:regulation of apoptotic signaling pathway
GO:1903827--P:regulation of cellular protein localization
GO:0003309--P:type B pancreatic cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003580	Anas platyrhynchos	66.67	9.00e-25	104.00
IUUC-Aca-004492	Anolis carolinensis	70.54	2.00e-46	178.00
IUUC-Ang-009806	Aspergillus niger	33.33	6.20e-02	28.50
IUUC-Ame-011818	Astyanax mexicanus	48.00	5.00e-34	137.00
IUUC-Bta-013459	Bos taurus	81.71	4.00e-71	260.00
IUUC-Cel-018173	Caenorhabditis elegans	30.30	1.40e-01	28.90
IUUC-Cja-019826	Callithrix jacchus	83.65	1.00e-70	258.00
IUUC-Cfa-021280	Canis familiaris	87.88	3.00e-78	284.00
IUUC-Cpo-022544	Cavia porcellus	75.27	6.00e-70	256.00
IUUC-Cre-022809	Chlamydomonas reinhardtii	38.36	8.00e-04	38.10
IUUC-Csa-023644	Chlorocebus sabaeus	82.91	4.00e-69	253.00
IUUC-Cho-024479	Choloepus hoffmanni	52.99	2.00e-28	117.00
IUUC-Cin-025505	Ciona intestinalis	28.00	1.00e-02	32.70
IUUC-Cme-027232	Cyanidioschyzon merolae	28.38	3.60e+00	25.00
IUUC-Dre-028350	Danio rerio	44.65	1.00e-20	92.40
IUUC-Dno-029207	Dasypus novemcinctus	80.29	7.00e-56	209.00
IUUC-Dor-030912	Dipodomys ordii	56.49	7.00e-37	146.00
IUUC-Dme-031988	Drosophila melanogaster	25.64	2.00e-01	28.50
IUUC-Eca-034007	Equus caballus	100.00	4.00e-21	92.00
IUUC-Fca-036350	Felis catus	87.50	5.00e-77	280.00
IUUC-Fal-037192	Ficedula albicollis	60.13	7.00e-45	172.00
IUUC-Gmo-038921	Gadus morhua	51.30	8.00e-36	142.00
IUUC-Gga-041016	Gallus gallus	61.11	7.00e-44	169.00
IUUC-Gac-042560	Gasterosteus aculeatus	45.57	5.00e-28	117.00
IUUC-Ggo-045419	Gorilla gorilla	82.80	4.00e-68	250.00
IUUC-Hsa-046547	Homo sapiens	82.80	4.00e-68	250.00
IUUC-Itr-048225	Ictidomys tridecemlineatus	85.62	3.00e-73	266.00
IUUC-Lch-050463	Latimeria chalumnae	55.56	4.00e-41	160.00
IUUC-Loc-052053	Lepisosteus oculatus	51.02	2.00e-38	151.00
IUUC-Laf-053893	Loxodonta africana	82.63	4.00e-74	270.00
IUUC-Mcc-055347	Macaca mulatta	61.17	2.00e-51	195.00
IUUC-Mdo-062169	Monodelphis domestica	63.54	3.00e-28	116.00
IUUC-Mmu-064366	Mus musculus	82.39	4.00e-61	227.00
IUUC-Mpu-066593	Mustela putorius furo	86.14	2.00e-77	281.00
IUUC-Mlu-066926	Myotis lucifugus	79.90	3.00e-75	274.00
IUUC-Nle-069724	Nomascus leucogenys	83.44	7.00e-69	253.00
IUUC-Opr-070679	Ochotona princeps	79.08	3.00e-66	243.00
IUUC-Ont-071332	Oreochromis niloticus	50.00	8.00e-35	139.00
IUUC-Ola-086869	Oryzias latipes	40.99	7.00e-29	119.00
IUUC-Oga-089124	Otolemur garnettii	82.63	3.00e-75	274.00
IUUC-Oar-089799	Ovis aries	92.08	7.00e-50	187.00
IUUC-Ptr-091186	Pan troglodytes	82.35	4.00e-49	186.00
IUUC-Pan-092150	Papio anubis	83.77	6.00e-68	249.00
IUUC-Psi-094039	Pelodiscus sinensis	57.32	4.00e-43	167.00
IUUC-Pma-094129	Petromyzon marinus	39.44	7.00e-21	93.20
IUUC-Pfo-096892	Poecilia formosa	44.67	2.00e-29	121.00
IUUC-Pab-097822	Pongo abelii	83.44	6.00e-69	253.00
IUUC-Pca-101058	Procavia capensis	76.85	6.00e-66	243.00
IUUC-Pva-102932	Pteropus vampyrus	86.08	4.00e-72	263.00
IUUC-Rno-105050	Rattus norvegicus	81.60	1.00e-70	258.00
IUUC-Sha-106738	Sarcophilus harrisii	78.35	2.00e-40	156.00
IUUC-Ssc-115973	Sus scrofa	83.13	1.00e-73	268.00
IUUC-Tgu-116663	Taeniopygia guttata	66.67	2.00e-31	126.00
IUUC-Tru-118654	Takifugu rubripes	50.34	6.00e-34	136.00
IUUC-Ttr-128418	Tursiops truncatus	81.13	9.00e-69	252.00
IUUC-Vpa-130268	Vicugna pacos	76.00	1.00e-37	148.00
IUUC-Xtr-132506	Xenopus tropicalis	56.49	3.00e-43	167.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence