iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000000102.5	ENSGALT00000063439.1	ENSGALP00000043588.1
ENSGALG00000000102.5	ENSGALT00000000141.5	ENSGALP00000000140.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.70e-43	148.1	6	143

Active Site

Position(s)	Description	Evidence
86	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk.. 87
           Rl +el+ l+++pp+gis+ ++    l+e++++i+G +dtpYe+g+F lei +pe+YPf+PPk++flt+i+hPn++++G++Cl++lk  
   Q: 6    RLSRELTMLSTEPPPGISCWQSGA-RLDELRAQIIGAADTPYEKGIFDLEIVVPERYPFEPPKIRFLTPIYHPNIDSAGRICLDVLKlp 93
           89**********************.5************************************************************998 PP
   S: 88   eeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkv 137
           ++ +W+p l++++ l+siq l+ epnp++pl +++++++k n++ +  ++
   Q: 94   PKGAWRPSLNISTLLTSIQLLMVEPNPDDPLMADISSEYKYNKQLFLINA 143
           99*****************************************9886665 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MQRASRLSRE LTMLSTEPPP GISCWQSGAR LDELRAQIIG AADTPYEKGI FDLEIVVPER 60
YPFEPPKIRF LTPIYHPNID SAGRICLDVL KLPPKGAWRP SLNISTLLTS IQLLMVEPNP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTTACGTCA TGGGCAGCAG TTATGGAGGG GTCGGCCGCT GAGGTGGGCC TCTGTGTGAG 60
CTGCGCTGGA GGAAAGGCTT TGGGAGGGGG GGTGAAGCCA AGGAACCCTC TGCGGGGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:0006281--P:DNA repair
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0044314--P:protein K27-linked ubiquitination
GO:0035519--P:protein K29-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0085020--P:protein K6-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0000209--P:protein polyubiquitination

KEGG

gga:421149

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000366	Aegilops tauschii	58.55	7.00e-50	191.00
IUUC-Aml-001392	Ailuropoda melanoleuca	70.41	5.00e-81	293.00
IUUC-Atr-003069	Amborella trichopoda	53.85	3.00e-52	198.00
IUUC-Apl-003914	Anas platyrhynchos	94.23	7.00e-87	311.00
IUUC-Aca-004381	Anolis carolinensis	74.11	1.00e-85	308.00
IUUC-Aly-006059	Arabidopsis lyrata	56.71	3.00e-49	188.00
IUUC-Ath-007669	Arabidopsis thaliana	66.96	1.00e-45	177.00
IUUC-Ame-011372	Astyanax mexicanus	65.00	6.00e-69	252.00
IUUC-Bta-012479	Bos taurus	67.37	5.00e-75	273.00
IUUC-Bdi-014043	Brachypodium distachyon	59.21	2.00e-53	203.00
IUUC-Bol-016011	Brassica oleracea	54.88	7.00e-48	184.00
IUUC-Bra-017419	Brassica rapa	54.27	2.00e-47	182.00
IUUC-Cja-019773	Callithrix jacchus	69.04	1.00e-77	281.00
IUUC-Cfa-020043	Canis familiaris	70.83	2.00e-79	287.00
IUUC-Cpo-021481	Cavia porcellus	70.31	5.00e-80	290.00
IUUC-Cre-022823	Chlamydomonas reinhardtii	46.62	2.00e-31	127.00
IUUC-Csa-024083	Chlorocebus sabaeus	69.90	1.00e-79	288.00
IUUC-Cho-024386	Choloepus hoffmanni	75.76	8.00e-77	278.00
IUUC-Cin-025419	Ciona intestinalis	65.56	1.00e-59	221.00
IUUC-Csv-026224	Ciona savignyi	65.43	6.00e-64	236.00
IUUC-Cme-027179	Cyanidioschyzon merolae	51.63	9.00e-41	158.00
IUUC-Dre-028800	Danio rerio	75.00	5.00e-73	266.00
IUUC-Dno-029833	Dasypus novemcinctus	71.43	4.00e-81	293.00
IUUC-Ete-032625	Echinops telfairi	73.72	7.00e-66	241.00
IUUC-Eca-033821	Equus caballus	77.07	5.00e-74	269.00
IUUC-Eeu-034578	Erinaceus europaeus	71.21	5.00e-52	195.00
IUUC-Fca-036398	Felis catus	70.83	9.00e-80	288.00
IUUC-Fal-037564	Ficedula albicollis	79.49	7.00e-90	322.00
IUUC-Gmo-039142	Gadus morhua	80.52	1.00e-72	265.00
IUUC-Gac-041370	Gasterosteus aculeatus	75.32	2.00e-71	260.00
IUUC-Ggo-045370	Gorilla gorilla	69.90	4.00e-79	286.00
IUUC-Hsa-046513	Homo sapiens	70.41	1.00e-79	288.00
IUUC-Hvu-047694	Hordeum vulgare	58.55	9.00e-52	197.00
IUUC-Itr-049076	Ictidomys tridecemlineatus	71.35	2.00e-78	285.00
IUUC-Lch-050484	Latimeria chalumnae	63.08	6.00e-66	243.00
IUUC-Loc-051967	Lepisosteus oculatus	64.77	2.00e-73	267.00
IUUC-Laf-053377	Loxodonta africana	69.39	1.00e-79	288.00
IUUC-Mcc-055453	Macaca mulatta	69.90	2.00e-79	288.00
IUUC-Meu-056745	Macropus eugenii	70.37	2.00e-76	278.00
IUUC-Mga-059729	Meleagris gallopavo	94.82	3.00e-99	353.00
IUUC-Mmr-060581	Microcebus murinus	69.90	1.00e-79	288.00
IUUC-Mdo-062434	Monodelphis domestica	70.31	8.00e-76	277.00
IUUC-Mmu-064379	Mus musculus	67.54	3.00e-76	277.00
IUUC-Mac-064647	Musa acuminata	57.64	3.00e-46	177.00
IUUC-Mpu-066713	Mustela putorius furo	69.79	6.00e-78	282.00
IUUC-Mlu-067525	Myotis lucifugus	77.92	1.00e-73	267.00
IUUC-Nle-069757	Nomascus leucogenys	70.41	7.00e-80	289.00
IUUC-Opr-070756	Ochotona princeps	68.37	8.00e-78	282.00
IUUC-Ont-071956	Oreochromis niloticus	66.13	5.00e-73	266.00
IUUC-Oan-072745	Ornithorhynchus anatinus	80.25	4.00e-76	276.00
IUUC-Ocu-074423	Oryctolagus cuniculus	69.90	4.00e-80	290.00
IUUC-Oba-075569	Oryza barthii	59.87	4.00e-52	199.00
IUUC-Obr-076131	Oryza brachyantha	58.55	2.00e-50	193.00
IUUC-Ogl-077132	Oryza glaberrima	59.87	4.00e-52	199.00
IUUC-Ogu-078880	Oryza glumaepatula	59.21	7.00e-52	197.00
IUUC-Oin-079748	Oryza indica	59.21	7.00e-52	197.00
IUUC-Olo-080501	Oryza longistaminata	59.21	1.00e-52	201.00
IUUC-Ome-081248	Oryza meridionalis	59.87	4.00e-52	198.00
IUUC-Oni-083033	Oryza nivara	59.21	7.00e-52	197.00
IUUC-Opu-083664	Oryza punctata	59.21	6.00e-52	198.00
IUUC-Oru-084580	Oryza rufipogon	59.21	7.00e-52	197.00
IUUC-Osa-085721	Oryza sativa	59.21	7.00e-52	197.00
IUUC-Ola-087559	Oryzias latipes	72.12	1.00e-71	261.00
IUUC-Oga-088420	Otolemur garnettii	71.50	5.00e-80	289.00
IUUC-Oar-090082	Ovis aries	65.62	2.00e-73	268.00
IUUC-Ptr-091134	Pan troglodytes	69.90	4.00e-79	286.00
IUUC-Pan-091735	Papio anubis	69.90	1.00e-79	288.00
IUUC-Psi-094064	Pelodiscus sinensis	75.13	2.00e-85	307.00
IUUC-Pma-094609	Petromyzon marinus	70.20	1.00e-64	237.00
IUUC-Ppa-095553	Physcomitrella patens	58.94	4.00e-50	192.00
IUUC-Pfo-096710	Poecilia formosa	71.60	8.00e-71	259.00
IUUC-Pab-098126	Pongo abelii	70.41	1.00e-79	288.00
IUUC-Pop-099108	Populus trichocarpa	47.52	6.00e-48	185.00
IUUC-Pca-100338	Procavia capensis	70.41	2.00e-80	290.00
IUUC-Ppe-101239	Prunus persica	58.99	6.00e-45	175.00
IUUC-Pva-102756	Pteropus vampyrus	66.43	1.00e-51	194.00
IUUC-Rno-105211	Rattus norvegicus	66.49	5.00e-74	270.00
IUUC-Sha-106969	Sarcophilus harrisii	65.82	2.00e-67	248.00
IUUC-Smo-109052	Selaginella moellendorffii	54.19	3.00e-44	170.00
IUUC-Sit-110464	Setaria italica	60.14	2.00e-50	193.00
IUUC-Sly-110971	Solanum lycopersicum	60.13	2.00e-48	186.00
IUUC-Stu-112126	Solanum tuberosum	60.40	1.00e-48	187.00
IUUC-Sar-113633	Sorex araneus	70.83	9.00e-78	282.00
IUUC-Sbi-114875	Sorghum bicolor	59.87	3.00e-51	196.00
IUUC-Ssc-116375	Sus scrofa	69.79	2.00e-75	274.00
IUUC-Tgu-117292	Taeniopygia guttata	86.93	2.00e-79	287.00
IUUC-Tru-118157	Takifugu rubripes	68.59	7.00e-60	222.00
IUUC-Tsy-119260	Tarsius syrichta	70.53	1.00e-77	281.00
IUUC-Tni-120162	Tetraodon nigroviridis	73.33	5.00e-73	266.00
IUUC-Tca-121255	Theobroma cacao	56.29	2.00e-36	146.00
IUUC-Tae-123184	Triticum aestivum	58.55	8.00e-50	191.00
IUUC-Tbe-127296	Tupaia belangeri	68.37	9.00e-79	285.00
IUUC-Ttr-128443	Tursiops truncatus	70.62	2.00e-78	284.00
IUUC-Vpa-130689	Vicugna pacos	67.71	9.00e-76	275.00
IUUC-Vvi-130925	Vitis vinifera	58.17	6.00e-47	179.00
IUUC-Xma-133779	Xiphophorus maculatus	72.73	3.00e-72	263.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence