iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afu-008996

Ensembl Protein ID

CADAFUAP00004895

UniProt Accession

Q4X0E7; Q4X0E7_ASPFU

Genbank Protein ID

EAL93668.2

Protein Name

NEDD8 activating enzyme (UbaC), putative

Genbank Nucleotide ID

AAHF01000001

Gene Name

AFUA_2G13730

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADAFUAG00004895	CADAFUAT00004895	CADAFUAP00004895

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.10e-79	267.6	31	222

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 9    GeeaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesitele 101
           G e   +l+s+k+  +GagglGcE+lKnL+l+G++ i+v+Dmdt+++snlnrqFLfr+ d+gk+KAevaa ++ +++  v+++++  +i++++
   Q: 31   GPETISALESSKI--LGAGGLGCEILKNLALSGFKDIHVIDMDTIDISNLNRQFLFRQTDIGKPKAEVAASFVEKRVKGVKITPYVGKIQDKD 121
           6667778888886..6***************************************************************************** PP
   S: 102  eeivFfkkfdvVvlaldnrearrkvnrlclna........rvpliesgtlGllGqvrviikgltecyscsd..dppqktiPfctlketpnaae 184
           e+  ++ +f+++v++ld++earr++n+ ++ +         +pli++gt+G++Gq+rvi++ l  c++c+     p+  +P+ct++  p++++
   Q: 122  ED--YYMQFKIIVCGLDSIEARRWINSTLIGMvdpenpesLKPLIDGGTEGFKGQARVILPTLSSCIECQLdmHAPRPAVPLCTIATIPRQPQ 212
           **..**************************99***************************************999******************* PP
   S: 185  htiewavlfnkll 197
           h+iewa    +++
   Q: 213  HCIEWA---HQIA 222
           ******...3333 PP

Organism

Aspergillus fumigatus

Protein Sequence
(Fasta)

MAPLSSTSRW RHLYSVLSKP GPYSDEDWVP GPETISALES SKILGAGGLG CEILKNLALS 60
GFKDIHVIDM DTIDISNLNR QFLFRQTDIG KPKAEVAASF VEKRVKGVKI TPYVGKIQDK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCACCTC TAAGTTCTAC GTCTCGGTGG TATGCATTAA CTTGGAGGGT CCAAGGCAAG 60
AATGGTTAAC GTGAAGCAGG CGGCACCTTT ACTCGGTCTT GTCGAAACCA GGTCCTTACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014929--E2_binding
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR030468--Uba3

Pfam

PF08825--E2_bind
PF00899--ThiF

SMART

SM01181--E2_bind

Gene Ontology

GO:0016881--F:acid-amino acid ligase activity
GO:0005524--F:ATP binding
GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

KEGG

afm:AFUA_2G13730

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001124	Aegilops tauschii	49.55	2.00e-83	300.00
IUUC-Aml-001578	Ailuropoda melanoleuca	50.00	3.00e-123	433.00
IUUC-Atr-002591	Amborella trichopoda	48.38	2.00e-95	340.00
IUUC-Apl-003671	Anas platyrhynchos	51.17	9.00e-127	445.00
IUUC-Aca-004749	Anolis carolinensis	51.06	1.00e-123	434.00
IUUC-Aly-005747	Arabidopsis lyrata	48.03	2.00e-97	347.00
IUUC-Ath-006623	Arabidopsis thaliana	48.03	8.00e-98	348.00
IUUC-Ago-007934	Ashbya gossypii	42.14	4.00e-66	243.00
IUUC-Acl-008047	Aspergillus clavatus	93.32	0.00e+00	830.00
IUUC-Afl-008615	Aspergillus flavus	73.30	6.00e-158	548.00
IUUC-Ani-009281	Aspergillus nidulans	79.04	3.00e-174	602.00
IUUC-Ang-009539	Aspergillus niger	91.41	0.00e+00	752.00
IUUC-Aor-010151	Aspergillus oryzae	85.78	0.00e+00	738.00
IUUC-Ate-010502	Aspergillus terreus	90.97	0.00e+00	750.00
IUUC-Ame-011837	Astyanax mexicanus	51.88	4.00e-117	412.00
IUUC-Bgr-012068	Blumeria graminis	61.23	3.00e-156	543.00
IUUC-Bta-013003	Bos taurus	50.47	2.00e-124	437.00
IUUC-Bci-013983	Botrytis cinerea	65.95	1.00e-158	550.00
IUUC-Bdi-014429	Brachypodium distachyon	48.88	5.00e-94	336.00
IUUC-Bol-015813	Brassica oleracea	48.27	3.00e-89	320.00
IUUC-Bra-018023	Brassica rapa	50.00	4.00e-88	316.00
IUUC-Cel-018684	Caenorhabditis elegans	47.76	4.00e-112	396.00
IUUC-Cja-019200	Callithrix jacchus	50.47	4.00e-122	429.00
IUUC-Cfa-021038	Canis familiaris	50.47	2.00e-124	437.00
IUUC-Cre-022778	Chlamydomonas reinhardtii	48.79	4.00e-107	379.00
IUUC-Csa-024079	Chlorocebus sabaeus	50.70	1.00e-124	438.00
IUUC-Cho-025052	Choloepus hoffmanni	44.60	4.00e-107	379.00
IUUC-Cin-025113	Ciona intestinalis	50.70	2.00e-118	417.00
IUUC-Csv-026231	Ciona savignyi	49.07	5.00e-120	422.00
IUUC-Cgl-026535	Colletotrichum gloeosporioides	61.72	6.00e-148	515.00
IUUC-Cne-026850	Cryptococcus neoformans	54.78	9.00e-125	438.00
IUUC-Cme-027275	Cyanidioschyzon merolae	35.73	1.00e-65	242.00
IUUC-Dre-028751	Danio rerio	50.94	4.00e-116	409.00
IUUC-Dno-029571	Dasypus novemcinctus	50.23	3.00e-124	436.00
IUUC-Dor-030395	Dipodomys ordii	52.20	5.00e-123	432.00
IUUC-Dse-031329	Dothistroma septosporum	64.50	5.00e-159	552.00
IUUC-Dme-031776	Drosophila melanogaster	48.14	9.00e-110	388.00
IUUC-Ete-032894	Echinops telfairi	48.48	6.00e-39	153.00
IUUC-Eca-034389	Equus caballus	50.47	5.00e-124	436.00
IUUC-Eeu-035152	Erinaceus europaeus	46.08	1.00e-96	345.00
IUUC-Fca-036032	Felis catus	50.47	3.00e-124	436.00
IUUC-Fal-037506	Ficedula albicollis	50.94	2.00e-126	443.00
IUUC-Fox-037871	Fusarium oxysporum	63.66	3.00e-132	462.00
IUUC-Fso-038350	Fusarium solani	63.94	1.00e-151	527.00
IUUC-Gmo-039246	Gadus morhua	51.42	2.00e-117	414.00
IUUC-Ggr-039859	Gaeumannomyces graminis	64.15	2.00e-149	520.00
IUUC-Gga-040843	Gallus gallus	49.30	8.00e-119	418.00
IUUC-Gac-042610	Gasterosteus aculeatus	51.65	8.00e-118	415.00
IUUC-Gma-042744	Glycine max	48.92	6.00e-93	332.00
IUUC-Ggo-044788	Gorilla gorilla	50.82	1.00e-123	434.00
IUUC-Hsa-045849	Homo sapiens	50.94	6.00e-125	439.00
IUUC-Hvu-047819	Hordeum vulgare	52.02	1.00e-84	304.00
IUUC-Itr-047863	Ictidomys tridecemlineatus	50.47	1.00e-124	437.00
IUUC-Kpa-049393	Komagataella pastoris	60.95	2.00e-110	390.00
IUUC-Lch-049471	Latimeria chalumnae	51.33	9.00e-116	408.00
IUUC-Lpe-051297	Leersia perrieri	50.12	3.00e-105	373.00
IUUC-Loc-052910	Lepisosteus oculatus	51.82	2.00e-115	407.00
IUUC-Lma-053181	Leptosphaeria maculans	68.65	1.00e-168	583.00
IUUC-Laf-054314	Loxodonta africana	49.88	1.00e-122	431.00
IUUC-Mcc-054870	Macaca mulatta	50.94	4.00e-125	439.00
IUUC-Meu-056574	Macropus eugenii	43.56	3.00e-58	217.00
IUUC-Mor-056919	Magnaporthe oryzae	61.85	1.00e-147	514.00
IUUC-Mpo-057614	Magnaporthe poae	63.68	1.00e-142	497.00
IUUC-Mtr-058110	Medicago truncatula	48.41	2.00e-90	324.00
IUUC-Mla-058949	Melampsora laricipopulina	56.61	2.00e-126	443.00
IUUC-Mga-059455	Meleagris gallopavo	51.17	3.00e-126	443.00
IUUC-Mvi-060270	Microbotryum violaceum	56.68	1.00e-133	467.00
IUUC-Mmr-061155	Microcebus murinus	50.48	1.00e-119	421.00
IUUC-Mdo-062037	Monodelphis domestica	50.35	5.00e-123	432.00
IUUC-Mmu-063670	Mus musculus	50.94	1.00e-124	437.00
IUUC-Mac-064711	Musa acuminata	51.98	7.00e-97	345.00
IUUC-Mpu-066734	Mustela putorius furo	50.23	5.00e-124	435.00
IUUC-Mlu-067068	Myotis lucifugus	50.35	4.00e-124	436.00
IUUC-Nfi-068349	Neosartorya fischeri	98.81	0.00e+00	823.00
IUUC-Ncr-068626	Neurospora crassa	64.87	4.00e-147	512.00
IUUC-Nle-069366	Nomascus leucogenys	53.63	2.00e-114	404.00
IUUC-Ont-072196	Oreochromis niloticus	52.24	2.00e-118	417.00
IUUC-Oan-073511	Ornithorhynchus anatinus	50.70	8.00e-124	435.00
IUUC-Ocu-073773	Oryctolagus cuniculus	50.70	2.00e-124	437.00
IUUC-Oba-075726	Oryza barthii	45.39	3.00e-91	327.00
IUUC-Obr-076286	Oryza brachyantha	48.64	7.00e-102	362.00
IUUC-Ogu-078473	Oryza glumaepatula	45.39	4.00e-91	326.00
IUUC-Oin-079393	Oryza indica	49.63	4.00e-104	369.00
IUUC-Olo-080446	Oryza longistaminata	47.19	2.00e-94	337.00
IUUC-Ome-081737	Oryza meridionalis	47.64	2.00e-94	337.00
IUUC-Oni-082853	Oryza nivara	45.39	3.00e-91	327.00
IUUC-Opu-083590	Oryza punctata	49.63	2.00e-103	367.00
IUUC-Oru-084184	Oryza rufipogon	45.39	3.00e-91	327.00
IUUC-Osa-085402	Oryza sativa	49.63	4.00e-104	369.00
IUUC-Ola-086615	Oryzias latipes	48.94	1.00e-110	391.00
IUUC-Olu-087738	Ostreococcus lucimarinus	44.99	9.00e-91	325.00
IUUC-Oga-088101	Otolemur garnettii	50.70	2.00e-124	437.00
IUUC-Oar-090293	Ovis aries	50.12	6.00e-123	432.00
IUUC-Ptr-090503	Pan troglodytes	50.94	6.00e-125	439.00
IUUC-Pan-092477	Papio anubis	49.42	9.00e-120	421.00
IUUC-Psi-093442	Pelodiscus sinensis	50.70	9.00e-123	431.00
IUUC-Pma-094247	Petromyzon marinus	52.10	6.00e-119	419.00
IUUC-Pno-094780	Phaeosphaeria nodorum	69.55	3.00e-166	576.00
IUUC-Ppa-095961	Physcomitrella patens	48.43	2.00e-115	407.00
IUUC-Pfo-097137	Poecilia formosa	52.47	1.00e-120	424.00
IUUC-Pab-098060	Pongo abelii	50.70	3.00e-117	413.00
IUUC-Pop-099914	Populus trichocarpa	51.56	1.00e-98	351.00
IUUC-Pca-100500	Procavia capensis	46.65	2.00e-87	314.00
IUUC-Ppe-102008	Prunus persica	52.31	7.00e-91	325.00
IUUC-Pva-103095	Pteropus vampyrus	57.65	2.00e-65	241.00
IUUC-Pgr-103666	Puccinia graminis	54.55	3.00e-126	443.00
IUUC-Ptt-103901	Puccinia triticina	54.61	5.00e-127	446.00
IUUC-Pte-104198	Pyrenophora teres	67.30	2.00e-166	577.00
IUUC-Pyt-104792	Pyrenophora triticirepentis	67.62	7.00e-167	578.00
IUUC-Rno-105446	Rattus norvegicus	50.94	2.00e-124	437.00
IUUC-Sce-106355	Saccharomyces cerevisiae	39.26	1.00e-61	228.00
IUUC-Sha-106664	Sarcophilus harrisii	50.59	5.00e-124	436.00
IUUC-Sja-107982	Schizosaccharomyces japonicus	48.33	4.00e-114	402.00
IUUC-Spo-108345	Schizosaccharomyces pombe	47.89	1.00e-113	401.00
IUUC-Ssl-108540	Sclerotinia sclerotiorum	63.06	4.00e-146	509.00
IUUC-Smo-109133	Selaginella moellendorffii	48.41	2.00e-118	417.00
IUUC-Sit-109724	Setaria italica	49.25	1.00e-92	332.00
IUUC-Sly-110916	Solanum lycopersicum	51.12	4.00e-93	333.00
IUUC-Stu-112236	Solanum tuberosum	51.12	3.00e-93	333.00
IUUC-Sar-113044	Sorex araneus	51.65	3.00e-117	413.00
IUUC-Sbi-114276	Sorghum bicolor	49.75	2.00e-91	327.00
IUUC-Sre-114963	Sporisorium reilianum	60.49	2.00e-135	473.00
IUUC-Ssc-116301	Sus scrofa	50.35	4.00e-123	433.00
IUUC-Tgu-117265	Taeniopygia guttata	50.94	5.00e-126	442.00
IUUC-Tru-117526	Takifugu rubripes	51.88	4.00e-116	409.00
IUUC-Tsy-119483	Tarsius syrichta	51.70	8.00e-122	428.00
IUUC-Tni-120363	Tetraodon nigroviridis	51.89	3.00e-118	416.00
IUUC-Tca-121731	Theobroma cacao	49.01	2.00e-91	327.00
IUUC-Tre-122221	Trichoderma reesei	64.21	1.00e-135	474.00
IUUC-Tvi-122352	Trichoderma virens	62.03	2.00e-152	530.00
IUUC-Tae-123864	Triticum aestivum	49.62	2.00e-93	334.00
IUUC-Tur-126070	Triticum urartu	47.80	3.00e-73	266.00
IUUC-Tme-127199	Tuber melanosporum	68.45	1.00e-150	523.00
IUUC-Tbe-128076	Tupaia belangeri	50.47	2.00e-124	436.00
IUUC-Ttr-128695	Tursiops truncatus	58.33	1.00e-47	182.00
IUUC-Uma-129638	Ustilago maydis	60.60	3.00e-135	473.00
IUUC-Vda-129963	Verticillium dahliae	62.56	3.00e-140	489.00
IUUC-Vpa-130637	Vicugna pacos	45.05	8.00e-104	368.00
IUUC-Vvi-131613	Vitis vinifera	51.73	3.00e-91	327.00
IUUC-Xtr-132924	Xenopus tropicalis	49.65	2.00e-112	397.00
IUUC-Xma-133356	Xiphophorus maculatus	52.47	2.00e-120	424.00
IUUC-Yli-134365	Yarrowia lipolytica	60.67	8.00e-134	468.00
IUUC-Zma-135941	Zea mays	45.54	2.00e-87	314.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence