iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096150

Ensembl Protein ID

ENSPFOP00000018573.1

UniProt Accession

A0A087YKM0; A0A087YKM0_POEFO

Genbank Protein ID

ENSPFOP00000018573

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01022103

Gene Name

EML6 (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000018415.1	ENSPFOT00000018595.1	ENSPFOP00000018573.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.90e-53	175.6	105	143
UBD/Beta-Prp	1.30e-119	399.5	59	264

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdD..gtikvWDlrtgvll 36
           Ht +v claf sd  +l+s + D  +t+ +WD+r+g+++
   Q: 105  HTHGVACLAFdSDgQRLASVGLDakNTVCIWDWRRGRVV 143
           99*********999*******9999**********9976 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtl 90
           gh+++ i+ ++++pdk ++atg  ++d  i +wd+  +++++ l   h+ +v+++ f++dg+ l++++ D  +t+++wd + g  v   
   Q: 59   GHNDDIIS-LAIHPDKIQVATGqvGKDPYICIWDTYAMQTVSILrDVHTHGVACLAFDSDGQRLASVGLDakNTVCIWDWRRGRVVAMA 146
           78888888.99**********95558999***************889****************************************** PP
   S: 91   kghedsvlslsfsp.sgdklvsGshdrtirvwdletgqclee..tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtl 175
           +gh+d++ ++ ++p ++++lvs + ++ i+ w l  +    +  ++ ++ ++ ++++v+  +  l  sG+l++ + +W+    +l+rt 
   Q: 147  TGHSDRIFDVCWDPfQTSRLVSCG-VKHIKFWTLCGNALTPKrgIFGKTGDLQTILCVSAAKdELTYSGALNGDIYVWKG--ITLIRTV 232
           **************999*****99.9********999999999955555555555555555559**************66..9****** PP
   S: 176  tgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           + +h   + s+   ++g  +++g++dg ++lwd+
   Q: 233  QAAHGAGIFSMHACEEG--FATGGRDGCIRLWDV 264
           ************99965..**************8 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MSDKTAPRCQ LRLEWIHGYR GHQCRNNLFY TAGKELVYFV AGVGVVYNTR EHTQKFYLGH 60
NDDIISLAIH PDKIQVATGQ VGKDPYICIW DTYAMQTVSI LRDVHTHGVA CLAFDSDGQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGGACA AAACGGCGCC GCGCTGCCAG CTGCGGCTGG AGTGGATCCA CGGCTACCGG 60
GGCCACCAGT GTCGGAACAA CCTGTTCTAC ACGGCGGGGA AGGAGCTGGT CTACTTTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-010713	Astyanax mexicanus	85.96	0.00e+00	3277.00
IUUC-Cfa-020041	Canis familiaris	79.89	0.00e+00	2992.00
IUUC-Cho-025038	Choloepus hoffmanni	77.72	0.00e+00	1187.00
IUUC-Gmo-039057	Gadus morhua	83.28	0.00e+00	3146.00
IUUC-Gac-042555	Gasterosteus aculeatus	92.77	0.00e+00	3497.00
IUUC-Loc-052642	Lepisosteus oculatus	84.26	0.00e+00	3202.00
IUUC-Meu-056618	Macropus eugenii	66.78	0.00e+00	1541.00
IUUC-Mdo-062462	Monodelphis domestica	79.46	0.00e+00	2951.00
IUUC-Opr-070213	Ochotona princeps	77.22	0.00e+00	1674.00
IUUC-Oan-073563	Ornithorhynchus anatinus	79.67	0.00e+00	3046.00
IUUC-Oga-088665	Otolemur garnettii	79.35	0.00e+00	2953.00
IUUC-Psi-093281	Pelodiscus sinensis	78.63	0.00e+00	3035.00
IUUC-Pab-098561	Pongo abelii	79.09	0.00e+00	2791.00
IUUC-Sha-107105	Sarcophilus harrisii	77.34	0.00e+00	2853.00
IUUC-Tru-118040	Takifugu rubripes	90.40	0.00e+00	3395.00
IUUC-Tni-120118	Tetraodon nigroviridis	86.07	0.00e+00	3314.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence