iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000017422.7	ENSRNOT00000045644.5	ENSRNOP00000039742.5
ENSRNOG00000017422.7	ENSRNOT00000085614.1	ENSRNOP00000073365.1
ENSRNOG00000017422.7	ENSRNOT00000084809.1	ENSRNOP00000075219.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	RAID2
Protein-protein Interaction
HINT
Post-translational Modifications (PTMs)
CPLM	dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-07	32.3	93	126

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd..tllvsGsdDgtikvWDlr 31
           gH    +c+ f ++  +l++sG+ Dg +++WDl+
   Q: 93   GHRRTPWCVTFhPTisGLIASGCLDGEVRIWDLH 126
           6777779*****76779***************97 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MKVVPEKNAV RILWGRERGT RAMGAQRLLQ ELVEDKTRWM KWEGKRVELP DSPTLDFLLA 60
FSPDRTLLAS THVNHNIYIT EVKTGKCVHS LIGHRRTPWC VTFHPTISGL IASGCLDGEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCCTTTGAT GTCTGGGCGT TCGTGTGTTC GATGATCTTT TGCAGCGTCT TCTAGGTTGA 60
TGTCTCCAGA GCGGCGGCGG CGGTGCCAGG TCCTGGACTG AGTTATCCGG GAGACCCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005930--C:axoneme
GO:0005829--C:cytosol
GO:0043231--C:intracellular membrane-bounded organelle
GO:0005739--C:mitochondrion
GO:0045335--C:phagocytic vesicle
GO:0006914--P:autophagy
GO:0009267--P:cellular response to starvation
GO:0010667--P:negative regulation of cardiac muscle cell apoptotic process
GO:0008285--P:negative regulation of cell proliferation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0021915--P:neural tube development
GO:0010508--P:positive regulation of autophagy
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:2000785--P:regulation of autophagosome assembly
GO:0031667--P:response to nutrient levels

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001917	Ailuropoda melanoleuca	96.12	0.00e+00	1786.00
IUUC-Atr-002557	Amborella trichopoda	36.32	5.00e-28	119.00
IUUC-Apl-004186	Anas platyrhynchos	81.23	0.00e+00	1937.00
IUUC-Aca-004419	Anolis carolinensis	76.57	0.00e+00	1793.00
IUUC-Aly-006308	Arabidopsis lyrata	36.45	1.00e-26	115.00
IUUC-Ath-007656	Arabidopsis thaliana	35.68	3.00e-26	114.00
IUUC-Ame-011354	Astyanax mexicanus	60.52	0.00e+00	1220.00
IUUC-Bta-012455	Bos taurus	92.59	0.00e+00	2157.00
IUUC-Bdi-014580	Brachypodium distachyon	40.49	6.00e-28	119.00
IUUC-Bol-016094	Brassica oleracea	38.59	1.00e-26	115.00
IUUC-Bra-017308	Brassica rapa	39.13	1.00e-27	118.00
IUUC-Cja-019073	Callithrix jacchus	94.40	1.00e-163	569.00
IUUC-Cfa-020994	Canis familiaris	92.09	0.00e+00	1494.00
IUUC-Cpo-022101	Cavia porcellus	94.31	0.00e+00	2197.00
IUUC-Csa-023273	Chlorocebus sabaeus	94.78	0.00e+00	1585.00
IUUC-Cin-025567	Ciona intestinalis	51.22	1.00e-54	207.00
IUUC-Csv-026005	Ciona savignyi	50.25	3.00e-54	204.00
IUUC-Dre-028282	Danio rerio	59.97	0.00e+00	1204.00
IUUC-Dno-029948	Dasypus novemcinctus	94.31	0.00e+00	2184.00
IUUC-Dor-030568	Dipodomys ordii	96.08	0.00e+00	1259.00
IUUC-Ete-032864	Echinops telfairi	92.65	0.00e+00	1164.00
IUUC-Eca-034392	Equus caballus	94.57	0.00e+00	1604.00
IUUC-Eeu-034440	Erinaceus europaeus	86.09	0.00e+00	1220.00
IUUC-Fca-035359	Felis catus	92.65	0.00e+00	2146.00
IUUC-Fal-037483	Ficedula albicollis	81.36	0.00e+00	1952.00
IUUC-Gmo-039343	Gadus morhua	75.36	0.00e+00	756.00
IUUC-Gga-040787	Gallus gallus	81.61	0.00e+00	1244.00
IUUC-Gac-041321	Gasterosteus aculeatus	61.86	0.00e+00	1328.00
IUUC-Gma-044022	Glycine max	35.15	4.00e-27	116.00
IUUC-Ggo-044775	Gorilla gorilla	94.64	0.00e+00	1041.00
IUUC-Hsa-045708	Homo sapiens	95.69	0.00e+00	2243.00
IUUC-Hvu-047536	Hordeum vulgare	39.76	2.00e-27	117.00
IUUC-Itr-048376	Ictidomys tridecemlineatus	96.82	0.00e+00	1261.00
IUUC-Lch-050255	Latimeria chalumnae	69.38	0.00e+00	1395.00
IUUC-Lpe-050684	Leersia perrieri	40.00	2.00e-28	121.00
IUUC-Loc-052881	Lepisosteus oculatus	68.60	0.00e+00	1389.00
IUUC-Laf-053342	Loxodonta africana	72.81	0.00e+00	1007.00
IUUC-Mcc-055848	Macaca mulatta	93.38	0.00e+00	2209.00
IUUC-Meu-056320	Macropus eugenii	84.09	0.00e+00	1087.00
IUUC-Mtr-058685	Medicago truncatula	38.10	4.00e-27	116.00
IUUC-Mga-059401	Meleagris gallopavo	84.68	0.00e+00	1680.00
IUUC-Mmr-061037	Microcebus murinus	94.85	0.00e+00	2188.00
IUUC-Mdo-062484	Monodelphis domestica	74.37	0.00e+00	1669.00
IUUC-Mmu-064090	Mus musculus	99.00	0.00e+00	2298.00
IUUC-Mac-065675	Musa acuminata	39.43	2.00e-27	117.00
IUUC-Mpu-066165	Mustela putorius furo	93.95	0.00e+00	1517.00
IUUC-Mlu-068038	Myotis lucifugus	94.00	0.00e+00	2263.00
IUUC-Nle-069361	Nomascus leucogenys	96.77	0.00e+00	1948.00
IUUC-Opr-070360	Ochotona princeps	91.71	0.00e+00	855.00
IUUC-Ont-071277	Oreochromis niloticus	62.23	0.00e+00	1324.00
IUUC-Oan-073623	Ornithorhynchus anatinus	82.76	0.00e+00	1046.00
IUUC-Ocu-074600	Oryctolagus cuniculus	96.11	0.00e+00	1385.00
IUUC-Oba-075024	Oryza barthii	33.06	7.00e-30	125.00
IUUC-Obr-076172	Oryza brachyantha	33.06	5.00e-30	126.00
IUUC-Ogl-077411	Oryza glaberrima	33.06	8.00e-30	125.00
IUUC-Ogu-078025	Oryza glumaepatula	36.68	1.00e-29	125.00
IUUC-Oni-082463	Oryza nivara	33.06	7.00e-30	126.00
IUUC-Opu-084041	Oryza punctata	33.06	2.00e-29	124.00
IUUC-Oru-085075	Oryza rufipogon	36.68	3.00e-29	124.00
IUUC-Osa-085781	Oryza sativa	33.06	8.00e-30	125.00
IUUC-Ola-086729	Oryzias latipes	63.23	0.00e+00	1347.00
IUUC-Olu-087735	Ostreococcus lucimarinus	37.90	1.00e-21	98.20
IUUC-Oga-089113	Otolemur garnettii	93.46	0.00e+00	2123.00
IUUC-Oar-090171	Ovis aries	94.37	0.00e+00	2043.00
IUUC-Ptr-090970	Pan troglodytes	95.69	0.00e+00	2244.00
IUUC-Pan-092778	Papio anubis	94.68	0.00e+00	1595.00
IUUC-Psi-093571	Pelodiscus sinensis	81.09	0.00e+00	1934.00
IUUC-Pma-094563	Petromyzon marinus	72.92	7.00e-104	369.00
IUUC-Ppa-095832	Physcomitrella patens	35.32	3.00e-28	120.00
IUUC-Pfo-097365	Poecilia formosa	60.70	0.00e+00	1249.00
IUUC-Pab-098647	Pongo abelii	95.84	0.00e+00	1235.00
IUUC-Pop-099742	Populus trichocarpa	38.71	2.00e-27	117.00
IUUC-Pca-101035	Procavia capensis	91.12	0.00e+00	1176.00
IUUC-Ppe-101411	Prunus persica	36.15	3.00e-27	117.00
IUUC-Pva-103187	Pteropus vampyrus	96.84	0.00e+00	923.00
IUUC-Sha-107612	Sarcophilus harrisii	84.34	0.00e+00	1974.00
IUUC-Smo-109107	Selaginella moellendorffii	37.93	9.00e-25	108.00
IUUC-Sit-110786	Setaria italica	39.88	3.00e-30	127.00
IUUC-Sly-110859	Solanum lycopersicum	36.67	8.00e-30	125.00
IUUC-Stu-112031	Solanum tuberosum	37.14	7.00e-30	125.00
IUUC-Sar-113242	Sorex araneus	94.03	0.00e+00	1066.00
IUUC-Ssc-116094	Sus scrofa	94.62	0.00e+00	2221.00
IUUC-Tru-118308	Takifugu rubripes	61.32	0.00e+00	1288.00
IUUC-Tsy-119552	Tarsius syrichta	93.07	0.00e+00	1226.00
IUUC-Tca-121616	Theobroma cacao	36.67	1.00e-28	121.00
IUUC-Tae-124768	Triticum aestivum	40.36	6.00e-28	119.00
IUUC-Tur-126480	Triticum urartu	40.36	3.00e-28	120.00
IUUC-Tbe-127902	Tupaia belangeri	93.49	0.00e+00	961.00
IUUC-Ttr-129278	Tursiops truncatus	92.51	0.00e+00	1181.00
IUUC-Vpa-130741	Vicugna pacos	88.63	0.00e+00	820.00
IUUC-Vvi-131437	Vitis vinifera	44.90	4.00e-27	117.00
IUUC-Xtr-132247	Xenopus tropicalis	64.98	0.00e+00	1315.00
IUUC-Xma-134277	Xiphophorus maculatus	61.89	0.00e+00	1347.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence