iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-27	95.2	45	76

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDl 30
           gH++ v+cl++   ++ll+sGsdD    vWD+
   Q: 45   GHSGCVNCLEWneKGDLLASGSDDQHTIVWDP 76
           8**********65339***************6 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MAKVNITRDL IRRQIKERGA LSFERRYHVT DPFIRRLGLE AELQGHSGCV NCLEWNEKGD 60
LLASGSDDQH TIVWDPLHHK KLLSMHTGHT ANIFSVKFLP HAGDRILITG AADSKVHVHD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAACAGAGGA GGAGGGAGGG GAGTGCGTGT GTGAGAGCGC GCGAGGGAGT GTGAGTGTGT 60
GTGAGCGCGG GTGTGAGGCG GTGCGCAGGG GCGGGCGGAG GCGCTGTCCG GCCCCGGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50293--TPR_REGION
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00028--TPR
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0004857--F:enzyme inhibitor activity
GO:0055082--P:cellular chemical homeostasis
GO:0032869--P:cellular response to insulin stimulus
GO:0006006--P:glucose metabolic process
GO:0001701--P:in utero embryonic development
GO:0035264--P:multicellular organism growth
GO:0045717--P:negative regulation of fatty acid biosynthetic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0008361--P:regulation of cell size

KEGG

rno:313020

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000083	Aegilops tauschii	33.10	4.00e-31	129.00
IUUC-Aml-001699	Ailuropoda melanoleuca	96.61	0.00e+00	1328.00
IUUC-Atr-002509	Amborella trichopoda	31.39	1.00e-50	194.00
IUUC-Apl-003379	Anas platyrhynchos	92.47	0.00e+00	1280.00
IUUC-Aca-005202	Anolis carolinensis	89.82	0.00e+00	1248.00
IUUC-Aly-006475	Arabidopsis lyrata	31.93	4.00e-55	209.00
IUUC-Ath-007666	Arabidopsis thaliana	31.81	1.00e-54	207.00
IUUC-Afl-008592	Aspergillus flavus	27.68	2.00e-25	111.00
IUUC-Ani-009263	Aspergillus nidulans	27.62	2.00e-25	111.00
IUUC-Ang-009671	Aspergillus niger	27.32	5.00e-26	114.00
IUUC-Aor-010229	Aspergillus oryzae	27.68	8.00e-26	112.00
IUUC-Ame-010988	Astyanax mexicanus	81.18	0.00e+00	997.00
IUUC-Bdi-014100	Brachypodium distachyon	30.80	8.00e-51	195.00
IUUC-Bol-016409	Brassica oleracea	31.98	1.00e-51	198.00
IUUC-Bra-016979	Brassica rapa	32.41	5.00e-52	199.00
IUUC-Cel-018561	Caenorhabditis elegans	32.36	1.00e-33	137.00
IUUC-Cja-019212	Callithrix jacchus	95.42	0.00e+00	1287.00
IUUC-Cfa-020200	Canis familiaris	96.47	0.00e+00	1326.00
IUUC-Cpo-021739	Cavia porcellus	97.05	0.00e+00	1326.00
IUUC-Cre-022659	Chlamydomonas reinhardtii	33.85	3.00e-34	139.00
IUUC-Csa-023648	Chlorocebus sabaeus	97.49	0.00e+00	1330.00
IUUC-Cin-025155	Ciona intestinalis	44.90	1.00e-64	239.00
IUUC-Csv-026289	Ciona savignyi	46.17	4.00e-150	524.00
IUUC-Cme-027316	Cyanidioschyzon merolae	27.65	5.00e-27	117.00
IUUC-Dre-028745	Danio rerio	79.91	0.00e+00	1107.00
IUUC-Dno-029403	Dasypus novemcinctus	91.43	0.00e+00	1242.00
IUUC-Dor-030332	Dipodomys ordii	87.33	0.00e+00	1207.00
IUUC-Dme-031811	Drosophila melanogaster	37.54	9.00e-109	387.00
IUUC-Ete-032331	Echinops telfairi	80.48	0.00e+00	709.00
IUUC-Eca-033783	Equus caballus	96.62	0.00e+00	1328.00
IUUC-Eeu-034732	Erinaceus europaeus	94.54	0.00e+00	1281.00
IUUC-Fca-036543	Felis catus	96.61	0.00e+00	1328.00
IUUC-Fal-037245	Ficedula albicollis	91.96	0.00e+00	1288.00
IUUC-Gmo-039346	Gadus morhua	78.14	0.00e+00	1116.00
IUUC-Gga-041034	Gallus gallus	92.32	0.00e+00	1274.00
IUUC-Gac-041297	Gasterosteus aculeatus	78.76	0.00e+00	1103.00
IUUC-Gma-042727	Glycine max	31.41	4.00e-47	183.00
IUUC-Ggo-045309	Gorilla gorilla	97.49	0.00e+00	1330.00
IUUC-Hsa-046622	Homo sapiens	97.49	0.00e+00	1330.00
IUUC-Itr-049052	Ictidomys tridecemlineatus	96.13	0.00e+00	1155.00
IUUC-Lch-049810	Latimeria chalumnae	85.20	0.00e+00	1155.00
IUUC-Lpe-051600	Leersia perrieri	29.38	1.00e-67	251.00
IUUC-Loc-052088	Lepisosteus oculatus	84.79	0.00e+00	1183.00
IUUC-Laf-054097	Loxodonta africana	97.49	0.00e+00	1330.00
IUUC-Mcc-054848	Macaca mulatta	97.49	0.00e+00	1330.00
IUUC-Meu-056022	Macropus eugenii	72.77	0.00e+00	807.00
IUUC-Mtr-057735	Medicago truncatula	29.86	2.00e-45	177.00
IUUC-Mga-059622	Meleagris gallopavo	92.32	0.00e+00	1276.00
IUUC-Mmr-060709	Microcebus murinus	97.64	0.00e+00	1332.00
IUUC-Mdo-062401	Monodelphis domestica	94.53	0.00e+00	1291.00
IUUC-Mmu-063899	Mus musculus	98.82	0.00e+00	1353.00
IUUC-Mac-064840	Musa acuminata	30.54	9.00e-48	185.00
IUUC-Mpu-066268	Mustela putorius furo	96.47	0.00e+00	1326.00
IUUC-Mlu-067211	Myotis lucifugus	97.07	0.00e+00	843.00
IUUC-Nle-070019	Nomascus leucogenys	97.34	0.00e+00	1306.00
IUUC-Opr-071008	Ochotona princeps	97.34	0.00e+00	1350.00
IUUC-Ont-072123	Oreochromis niloticus	80.53	0.00e+00	1135.00
IUUC-Ocu-074166	Oryctolagus cuniculus	97.19	0.00e+00	1347.00
IUUC-Oba-075298	Oryza barthii	29.80	3.00e-43	170.00
IUUC-Obr-076849	Oryza brachyantha	27.69	1.00e-61	231.00
IUUC-Ogl-077515	Oryza glaberrima	29.80	4.00e-43	169.00
IUUC-Ogu-077968	Oryza glumaepatula	29.83	2.00e-39	157.00
IUUC-Oin-079231	Oryza indica	29.96	2.00e-38	154.00
IUUC-Olo-081045	Oryza longistaminata	29.75	2.00e-37	152.00
IUUC-Ome-081395	Oryza meridionalis	29.75	4.00e-37	149.00
IUUC-Oni-082801	Oryza nivara	29.80	2.00e-43	170.00
IUUC-Opu-083585	Oryza punctata	30.02	5.00e-43	169.00
IUUC-Oru-085163	Oryza rufipogon	29.25	5.00e-43	169.00
IUUC-Osa-085550	Oryza sativa	34.40	8.00e-29	120.00
IUUC-Ola-086925	Oryzias latipes	78.17	0.00e+00	1098.00
IUUC-Oga-088095	Otolemur garnettii	96.17	0.00e+00	1343.00
IUUC-Oar-090285	Ovis aries	94.99	0.00e+00	1288.00
IUUC-Ptr-091221	Pan troglodytes	97.49	0.00e+00	1330.00
IUUC-Pan-091771	Papio anubis	97.49	0.00e+00	1330.00
IUUC-Psi-093977	Pelodiscus sinensis	91.43	0.00e+00	1268.00
IUUC-Ppa-095373	Physcomitrella patens	30.74	3.00e-49	190.00
IUUC-Pfo-096640	Poecilia formosa	80.06	0.00e+00	1119.00
IUUC-Pab-098513	Pongo abelii	97.49	0.00e+00	1330.00
IUUC-Pop-098837	Populus trichocarpa	31.30	7.00e-45	175.00
IUUC-Pca-101095	Procavia capensis	88.48	0.00e+00	1176.00
IUUC-Ppe-101507	Prunus persica	29.02	3.00e-46	180.00
IUUC-Pva-102444	Pteropus vampyrus	96.90	0.00e+00	1326.00
IUUC-Sha-106614	Sarcophilus harrisii	95.57	0.00e+00	1316.00
IUUC-Smo-108844	Selaginella moellendorffii	32.50	4.00e-47	182.00
IUUC-Sit-110154	Setaria italica	33.44	1.00e-40	161.00
IUUC-Sly-111707	Solanum lycopersicum	31.29	2.00e-48	187.00
IUUC-Sar-113129	Sorex araneus	80.24	0.00e+00	1065.00
IUUC-Sbi-113858	Sorghum bicolor	30.00	4.00e-69	256.00
IUUC-Ssc-116275	Sus scrofa	97.20	0.00e+00	1329.00
IUUC-Tgu-117507	Taeniopygia guttata	92.32	0.00e+00	1279.00
IUUC-Tru-117969	Takifugu rubripes	77.73	0.00e+00	1116.00
IUUC-Tsy-119374	Tarsius syrichta	85.19	0.00e+00	844.00
IUUC-Tni-119887	Tetraodon nigroviridis	76.06	0.00e+00	1057.00
IUUC-Tca-121722	Theobroma cacao	31.71	2.00e-48	187.00
IUUC-Tae-124854	Triticum aestivum	34.84	2.00e-36	147.00
IUUC-Tur-125968	Triticum urartu	35.34	2.00e-32	135.00
IUUC-Tme-126910	Tuber melanosporum	34.26	2.00e-24	107.00
IUUC-Tbe-127511	Tupaia belangeri	89.94	5.00e-86	311.00
IUUC-Ttr-128390	Tursiops truncatus	93.51	0.00e+00	1252.00
IUUC-Uma-129509	Ustilago maydis	26.85	3.00e-13	70.90
IUUC-Vpa-130124	Vicugna pacos	58.35	2.00e-144	506.00
IUUC-Xtr-132290	Xenopus tropicalis	76.65	0.00e+00	1050.00
IUUC-Xma-134025	Xiphophorus maculatus	79.62	0.00e+00	1113.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence