iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098391

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01060124

Gene Name

WDR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000014606.2	ENSPPYT00000016981.2	ENSPPYP00000016318.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.90e-38	127.9	233	263
UBD/Beta-Prp	2.70e-61	207.5	56	277

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           H ++++++++ +d t+l+s+s+D+t k+WD+
   Q: 233  HDGGIYAISWsPDsTHLLSASGDKTSKIWDV 263
           99*********999****************7 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl..sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkg 92
           +h +++ + k++p++ ++a+g  +g++++wd+t++  l ++  +   ++++++ + +d+k ++ ++e   ++  v+  ++g+ v  ++g
   Q: 56   EHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYeyQPFAGKIKDIAWTEDSKRIAVVGEGreKFGAVFLWDSGSSVGEITG 144
           455666678*************************998777742334567***********99999999887777777789********* PP
   S: 93   hedsvlslsfspsg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgg 178
           h++ + s+++ +s+ ++l++Gs+d+ +  ++ +  +    t   h+++vncv+++pdgn ++++s+D+++ ++d ktg+ +  l  +++
   Q: 145  HNKVINSVDIKQSRpYRLATGSDDNCAAFFEGPPFKFKF-TIGDHSRFVNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCALggSKA 232
           ************999*****************9999998.99********************************************888 PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtd 223
           h++ +y +s+++++++l+s+s d+t k+wd+  +++v t+   ++
   Q: 233  HDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFPMGST 277
           ************************************999976544 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MPYEIKKVFA SLPQVERGVS KIIGGDPKGN NFLYTNGKCV ILRNIDNPAL ADIYTEHAHQ 60
VVVAKYAPSG FYIASGDVSG KLRIWDTTQK EHLLKYEYQP FAGKIKDIAW TEDSKRIAVV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGGCGGGGG AGGGGAGTGC CAGGTCCGCG CAGGCTCGCC GGGACCGCAG CCGCCGAGCC 60
GAGCGCTTGA CTATATATGG TCAAAGCTGG GGGCGAGCCG CGCGCGGGGC CGCGCTTCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011045--N2O_reductase_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0030043--P:actin filament fragmentation
GO:0043297--P:apical junction assembly
GO:0030865--P:cortical cytoskeleton organization
GO:0042247--P:establishment of planar polarity of follicular epithelium
GO:0045199--P:maintenance of epithelial cell apical/basal polarity
GO:0002446--P:neutrophil mediated immunity
GO:1990266--P:neutrophil migration
GO:0030220--P:platelet formation
GO:0030836--P:positive regulation of actin filament depolymerization
GO:0008360--P:regulation of cell shape
GO:0060307--P:regulation of ventricular cardiac muscle cell membrane repolarization
GO:0045214--P:sarcomere organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000457	Aegilops tauschii	35.47	3.00e-82	298.00
IUUC-Aml-002368	Ailuropoda melanoleuca	96.51	0.00e+00	1185.00
IUUC-Atr-003160	Amborella trichopoda	37.79	1.00e-115	410.00
IUUC-Apl-004012	Anas platyrhynchos	87.13	0.00e+00	1077.00
IUUC-Aca-004707	Anolis carolinensis	83.17	0.00e+00	1055.00
IUUC-Aly-006465	Arabidopsis lyrata	37.72	1.00e-110	393.00
IUUC-Ath-006740	Arabidopsis thaliana	37.24	5.00e-110	391.00
IUUC-Ago-007920	Ashbya gossypii	27.75	3.00e-72	266.00
IUUC-Acl-008262	Aspergillus clavatus	36.26	2.00e-106	379.00
IUUC-Afl-008471	Aspergillus flavus	30.37	1.00e-67	251.00
IUUC-Afu-008989	Aspergillus fumigatus	37.88	9.00e-96	344.00
IUUC-Ani-009167	Aspergillus nidulans	38.03	1.00e-115	410.00
IUUC-Ang-009595	Aspergillus niger	37.67	2.00e-103	369.00
IUUC-Aor-009908	Aspergillus oryzae	36.64	4.00e-103	368.00
IUUC-Ate-010580	Aspergillus terreus	37.85	5.00e-109	389.00
IUUC-Ame-011269	Astyanax mexicanus	60.25	6.00e-134	471.00
IUUC-Bgr-011996	Blumeria graminis	34.15	1.00e-106	380.00
IUUC-Bta-013278	Bos taurus	95.71	0.00e+00	1215.00
IUUC-Bci-013925	Botrytis cinerea	36.32	6.00e-108	384.00
IUUC-Bdi-014659	Brachypodium distachyon	36.07	2.00e-104	372.00
IUUC-Bol-016043	Brassica oleracea	35.78	6.00e-107	381.00
IUUC-Bra-017139	Brassica rapa	36.97	2.00e-109	390.00
IUUC-Cel-018417	Caenorhabditis elegans	41.39	6.00e-124	437.00
IUUC-Cja-019952	Callithrix jacchus	97.85	0.00e+00	1179.00
IUUC-Cfa-020225	Canis familiaris	96.53	0.00e+00	1198.00
IUUC-Cpo-021900	Cavia porcellus	94.84	0.00e+00	1178.00
IUUC-Csa-023028	Chlorocebus sabaeus	99.17	0.00e+00	1191.00
IUUC-Cho-025030	Choloepus hoffmanni	68.50	0.00e+00	761.00
IUUC-Cin-025152	Ciona intestinalis	56.03	3.00e-81	294.00
IUUC-Csv-025986	Ciona savignyi	37.85	2.00e-93	335.00
IUUC-Cgl-026597	Colletotrichum gloeosporioides	38.44	4.00e-112	398.00
IUUC-Cne-026814	Cryptococcus neoformans	34.41	1.00e-97	350.00
IUUC-Dre-027498	Danio rerio	80.51	7.00e-96	342.00
IUUC-Dno-029383	Dasypus novemcinctus	95.38	0.00e+00	1155.00
IUUC-Dor-030633	Dipodomys ordii	93.94	0.00e+00	1093.00
IUUC-Dse-031526	Dothistroma septosporum	38.23	2.00e-116	412.00
IUUC-Dme-031597	Drosophila melanogaster	48.43	3.00e-169	588.00
IUUC-Ete-032780	Echinops telfairi	83.28	0.00e+00	1034.00
IUUC-Eca-034306	Equus caballus	94.68	0.00e+00	1150.00
IUUC-Eeu-034531	Erinaceus europaeus	74.77	4.00e-138	484.00
IUUC-Fca-036301	Felis catus	97.17	0.00e+00	1214.00
IUUC-Fal-037361	Ficedula albicollis	87.11	0.00e+00	1124.00
IUUC-Fox-037924	Fusarium oxysporum	35.50	4.00e-101	362.00
IUUC-Fso-038199	Fusarium solani	34.96	9.00e-98	350.00
IUUC-Gmo-039238	Gadus morhua	71.99	0.00e+00	893.00
IUUC-Ggr-039830	Gaeumannomyces graminis	35.33	4.00e-96	345.00
IUUC-Gga-040235	Gallus gallus	88.45	0.00e+00	1107.00
IUUC-Gac-042363	Gasterosteus aculeatus	71.66	0.00e+00	925.00
IUUC-Gma-044189	Glycine max	37.48	1.00e-113	403.00
IUUC-Ggo-044632	Gorilla gorilla	97.03	0.00e+00	1160.00
IUUC-Hsa-045792	Homo sapiens	98.84	0.00e+00	1216.00
IUUC-Hvu-047517	Hordeum vulgare	35.68	1.00e-108	387.00
IUUC-Itr-048076	Ictidomys tridecemlineatus	96.17	0.00e+00	1182.00
IUUC-Kpa-049183	Komagataella pastoris	32.57	3.00e-84	305.00
IUUC-Lch-050428	Latimeria chalumnae	76.61	0.00e+00	1007.00
IUUC-Lpe-051306	Leersia perrieri	36.11	3.00e-109	389.00
IUUC-Loc-052096	Lepisosteus oculatus	71.75	0.00e+00	905.00
IUUC-Lma-053313	Leptosphaeria maculans	38.95	3.00e-116	414.00
IUUC-Laf-054060	Loxodonta africana	93.07	0.00e+00	1143.00
IUUC-Mcc-055619	Macaca mulatta	97.05	0.00e+00	1162.00
IUUC-Meu-056689	Macropus eugenii	77.89	0.00e+00	635.00
IUUC-Mor-056940	Magnaporthe oryzae	35.66	1.00e-97	350.00
IUUC-Mpo-057557	Magnaporthe poae	28.53	1.00e-57	217.00
IUUC-Mtr-057922	Medicago truncatula	36.50	7.00e-111	394.00
IUUC-Mla-059103	Melampsora laricipopulina	33.45	4.00e-76	278.00
IUUC-Mga-060150	Meleagris gallopavo	88.08	0.00e+00	1095.00
IUUC-Mvi-060448	Microbotryum violaceum	30.76	1.00e-73	270.00
IUUC-Mmr-061226	Microcebus murinus	95.21	0.00e+00	1170.00
IUUC-Mdo-062674	Monodelphis domestica	92.41	0.00e+00	1154.00
IUUC-Mmu-064170	Mus musculus	95.21	0.00e+00	1188.00
IUUC-Mac-065124	Musa acuminata	38.13	9.00e-114	404.00
IUUC-Mpu-066001	Mustela putorius furo	93.32	0.00e+00	1181.00
IUUC-Mlu-067253	Myotis lucifugus	94.01	0.00e+00	1174.00
IUUC-Nfi-068550	Neosartorya fischeri	37.80	1.00e-110	393.00
IUUC-Ncr-068948	Neurospora crassa	36.98	1.00e-114	407.00
IUUC-Nle-070115	Nomascus leucogenys	95.30	0.00e+00	1096.00
IUUC-Opr-070254	Ochotona princeps	93.17	0.00e+00	1111.00
IUUC-Ont-071666	Oreochromis niloticus	75.74	0.00e+00	962.00
IUUC-Oan-073594	Ornithorhynchus anatinus	92.79	2.00e-169	587.00
IUUC-Ocu-074824	Oryctolagus cuniculus	94.06	0.00e+00	1140.00
IUUC-Oba-075010	Oryza barthii	36.50	2.00e-110	393.00
IUUC-Obr-076364	Oryza brachyantha	36.87	4.00e-111	395.00
IUUC-Ogl-077019	Oryza glaberrima	36.50	2.00e-110	393.00
IUUC-Ogu-078496	Oryza glumaepatula	36.50	2.00e-110	393.00
IUUC-Oin-080116	Oryza indica	36.66	5.00e-111	394.00
IUUC-Olo-080290	Oryza longistaminata	36.50	4.00e-110	392.00
IUUC-Ome-081969	Oryza meridionalis	36.50	2.00e-110	392.00
IUUC-Oni-082075	Oryza nivara	36.50	2.00e-110	393.00
IUUC-Opu-083959	Oryza punctata	36.54	3.00e-110	392.00
IUUC-Oru-084711	Oryza rufipogon	36.50	2.00e-110	393.00
IUUC-Osa-085958	Oryza sativa	36.66	5.00e-111	394.00
IUUC-Ola-086968	Oryzias latipes	76.57	0.00e+00	974.00
IUUC-Oga-089108	Otolemur garnettii	95.58	0.00e+00	1221.00
IUUC-Oar-089986	Ovis aries	89.67	0.00e+00	1117.00
IUUC-Ptr-091281	Pan troglodytes	99.17	0.00e+00	1208.00
IUUC-Pan-092585	Papio anubis	99.34	0.00e+00	1193.00
IUUC-Psi-093811	Pelodiscus sinensis	86.05	0.00e+00	1114.00
IUUC-Pma-094396	Petromyzon marinus	70.08	0.00e+00	907.00
IUUC-Pno-095086	Phaeosphaeria nodorum	37.78	2.00e-109	389.00
IUUC-Ppa-095876	Physcomitrella patens	36.17	3.00e-111	395.00
IUUC-Pfo-096973	Poecilia formosa	75.08	0.00e+00	992.00
IUUC-Pop-098850	Populus trichocarpa	37.03	6.00e-112	397.00
IUUC-Pca-100257	Procavia capensis	60.26	2.00e-91	330.00
IUUC-Ppe-101578	Prunus persica	38.07	1.00e-115	410.00
IUUC-Pva-102872	Pteropus vampyrus	89.79	0.00e+00	1130.00
IUUC-Pgr-103593	Puccinia graminis	33.00	6.00e-79	288.00
IUUC-Pte-104365	Pyrenophora teres	39.16	2.00e-111	396.00
IUUC-Pyt-104689	Pyrenophora triticirepentis	38.83	4.00e-114	405.00
IUUC-Rno-105737	Rattus norvegicus	95.87	0.00e+00	1221.00
IUUC-Sce-106383	Saccharomyces cerevisiae	28.91	2.00e-67	249.00
IUUC-Sha-107084	Sarcophilus harrisii	90.02	0.00e+00	1011.00
IUUC-Sja-107688	Schizosaccharomyces japonicus	35.47	1.00e-110	393.00
IUUC-Spo-108309	Schizosaccharomyces pombe	33.99	7.00e-97	348.00
IUUC-Ssl-108408	Sclerotinia sclerotiorum	35.99	2.00e-107	383.00
IUUC-Smo-109255	Selaginella moellendorffii	34.65	1.00e-99	357.00
IUUC-Sit-109962	Setaria italica	37.58	1.00e-112	400.00
IUUC-Sly-110897	Solanum lycopersicum	38.56	8.00e-117	414.00
IUUC-Stu-111971	Solanum tuberosum	38.56	2.00e-116	412.00
IUUC-Sar-113415	Sorex araneus	72.32	2.00e-109	389.00
IUUC-Sbi-114857	Sorghum bicolor	37.09	2.00e-110	392.00
IUUC-Sre-114900	Sporisorium reilianum	33.33	1.00e-90	327.00
IUUC-Tgu-117256	Taeniopygia guttata	87.04	0.00e+00	1121.00
IUUC-Tru-117871	Takifugu rubripes	69.92	0.00e+00	891.00
IUUC-Tsy-119172	Tarsius syrichta	96.67	7.00e-140	490.00
IUUC-Tni-120339	Tetraodon nigroviridis	69.97	0.00e+00	927.00
IUUC-Tca-121609	Theobroma cacao	37.32	2.00e-113	403.00
IUUC-Tre-122076	Trichoderma reesei	35.34	4.00e-93	335.00
IUUC-Tvi-122528	Trichoderma virens	34.32	9.00e-96	344.00
IUUC-Tae-123530	Triticum aestivum	35.73	6.00e-109	387.00
IUUC-Tur-126845	Triticum urartu	35.45	3.00e-81	295.00
IUUC-Tme-127217	Tuber melanosporum	35.15	1.00e-104	374.00
IUUC-Tbe-127526	Tupaia belangeri	93.56	0.00e+00	1165.00
IUUC-Ttr-128898	Tursiops truncatus	88.14	0.00e+00	1101.00
IUUC-Uma-129631	Ustilago maydis	32.30	6.00e-94	338.00
IUUC-Vda-129732	Verticillium dahliae	35.02	8.00e-93	334.00
IUUC-Vvi-131217	Vitis vinifera	38.21	2.00e-113	403.00
IUUC-Xtr-132860	Xenopus tropicalis	74.55	0.00e+00	952.00
IUUC-Xma-133830	Xiphophorus maculatus	75.41	0.00e+00	995.00
IUUC-Yli-134335	Yarrowia lipolytica	33.28	1.00e-76	280.00
IUUC-Zma-135907	Zea mays	37.25	2.00e-111	395.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence