iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025773

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

EAAA01000623

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000007771.3	ENSCINT00000015931.3	ENSCINP00000015931.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.70e-85	287.2	326	667

Active Site

Position(s)	Description	Evidence
635	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpd....lglflysen.dketlqpnpdsglknpehlklFeflGrllgkalqdg 85
            sd+ +++ v f+gE gld+gGv+re+++ll+k +++++     g+f+  ++  ++ + p++ds +    ++k+Fef+G+l+gk+l ++
   Q: 326  TSDWCRQFVVAFKGETGLDWGGVNREWIHLLCKIFFQSKdaggCGIFRSMKEdAQALVLPASDSEV----KIKHFEFAGKLVGKCLLES 410
           57999999******************************999999***7666537777888888875....8****************** PP
   S: 86   .......rlldlplsksfyklllgkklsledleevdpelyks.lkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVt 166
                  r + +++++sf+ +l+g + ++ ++e+ dp+ly s +k+i+e+   d+++++l+++ ++ +++ +  k+ +L+p+G+n+ Vt
   Q: 411  avggeyaRQVTARFARSFLAQLIGLPATFAHFESDDPDLYMSkVKYILEH---DVTDAELTFSEEQFTSSGSLSKVIDLVPNGANVAVT 496
           9999999***********************************9*****99...9***988888888888899999999*********** PP
   S: 167  neNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspai.qwFwevle 254
           n+Nk +Y +++++yrl e+ik++++ f +G+++++p +lls+F+e+elel++cG+++i+ +d+k ++  ++g+ ++ ++i  wFw+ ++
   Q: 497  NDNKIKYLNRIAQYRLSESIKNELALFIKGLTSIVPDHLLSVFDENELELVMCGSSKISPDDFKLHCVVNSGMDPTFQKIlSWFWSLIS 585
           ****************************************************************************988869******* PP
   S: 255  efsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
            f+++e +++LqF+Tg+s+lP+ Gf++l+p+ f i+  + ++  lP ++TCfn L+LP+Y+s++ l+++L + i+e+ +gF+l
   Q: 586  TFTQDELARLLQFTTGCSQLPPDGFKALEPK-FKISSiEYKTGGLPMAHTCFNELCLPNYESYDDLHKMLKISITEGiTGFGL 667
           *****************************99.6666659999***************************************97 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MNAEHSCLVR TAHTSLSVIT MTQATTHKMA IEACDEFGNS CSSRLNKHDF ENAFNLSIMK 60
CCDSVQYPAF TWEITCNKIL DQLTLCITVF EEGSFQAELS YQSEPLKNGI FDILVLTSSE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAACCAACAG ATGTGGGTGA AGCTTTATCG TTCAATGTGG AGGTATAGAA TAATTTATTT 60
AACTGCTTTT TAATGGTTTA AAGTCAACAT GACGTTTGTT ATCTTGTAAC TGTAAACTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001308	Ailuropoda melanoleuca	41.98	4.00e-148	517.00
IUUC-Apl-004071	Anas platyrhynchos	42.11	1.00e-145	509.00
IUUC-Aca-005218	Anolis carolinensis	42.94	3.00e-149	521.00
IUUC-Ame-011871	Astyanax mexicanus	42.39	2.00e-160	558.00
IUUC-Bta-012978	Bos taurus	42.11	2.00e-148	518.00
IUUC-Cja-019081	Callithrix jacchus	42.19	5.00e-149	520.00
IUUC-Cfa-020736	Canis familiaris	42.13	2.00e-146	511.00
IUUC-Cpo-021581	Cavia porcellus	42.04	6.00e-148	516.00
IUUC-Cho-024751	Choloepus hoffmanni	42.75	9.00e-147	512.00
IUUC-Csv-026090	Ciona savignyi	73.64	0.00e+00	1013.00
IUUC-Dre-027788	Danio rerio	42.62	1.00e-156	546.00
IUUC-Dno-030022	Dasypus novemcinctus	42.56	3.00e-149	521.00
IUUC-Dme-031577	Drosophila melanogaster	42.46	3.00e-143	501.00
IUUC-Ete-032402	Echinops telfairi	41.67	7.00e-141	493.00
IUUC-Eca-033908	Equus caballus	42.04	1.00e-148	518.00
IUUC-Eeu-034869	Erinaceus europaeus	48.30	9.00e-131	459.00
IUUC-Fca-036023	Felis catus	42.28	9.00e-149	519.00
IUUC-Fal-037477	Ficedula albicollis	42.56	1.00e-146	512.00
IUUC-Gmo-039197	Gadus morhua	42.41	7.00e-156	543.00
IUUC-Gga-040704	Gallus gallus	42.41	5.00e-147	513.00
IUUC-Gac-041511	Gasterosteus aculeatus	42.04	2.00e-157	548.00
IUUC-Ggo-044527	Gorilla gorilla	40.39	4.00e-138	484.00
IUUC-Hsa-046082	Homo sapiens	42.04	2.00e-148	518.00
IUUC-Itr-048168	Ictidomys tridecemlineatus	42.04	2.00e-148	518.00
IUUC-Lch-049772	Latimeria chalumnae	40.54	6.00e-136	477.00
IUUC-Loc-052541	Lepisosteus oculatus	41.73	3.00e-157	548.00
IUUC-Laf-053852	Loxodonta africana	42.49	2.00e-150	524.00
IUUC-Meu-056247	Macropus eugenii	32.18	1.00e-36	147.00
IUUC-Mga-060161	Meleagris gallopavo	42.56	8.00e-148	516.00
IUUC-Mmr-061447	Microcebus murinus	41.89	2.00e-147	514.00
IUUC-Mdo-062110	Monodelphis domestica	42.28	2.00e-146	511.00
IUUC-Mmu-064349	Mus musculus	41.59	7.00e-148	516.00
IUUC-Mpu-065824	Mustela putorius furo	41.87	3.00e-148	518.00
IUUC-Mlu-067729	Myotis lucifugus	41.74	1.00e-146	512.00
IUUC-Nle-069721	Nomascus leucogenys	41.89	1.00e-148	518.00
IUUC-Opr-070189	Ochotona princeps	42.11	1.00e-147	515.00
IUUC-Ont-072122	Oreochromis niloticus	42.28	8.00e-156	542.00
IUUC-Oan-072700	Ornithorhynchus anatinus	39.52	7.00e-131	459.00
IUUC-Ocu-074057	Oryctolagus cuniculus	42.04	3.00e-148	517.00
IUUC-Ola-087492	Oryzias latipes	42.37	2.00e-158	551.00
IUUC-Oga-088084	Otolemur garnettii	42.04	3.00e-147	514.00
IUUC-Oar-090354	Ovis aries	41.57	7.00e-145	506.00
IUUC-Ptr-091456	Pan troglodytes	42.04	2.00e-148	518.00
IUUC-Pan-092596	Papio anubis	41.44	2.00e-145	508.00
IUUC-Psi-092942	Pelodiscus sinensis	42.86	2.00e-146	511.00
IUUC-Pma-094662	Petromyzon marinus	48.25	1.00e-132	465.00
IUUC-Pfo-096838	Poecilia formosa	42.99	2.00e-155	541.00
IUUC-Pab-097849	Pongo abelii	41.89	6.00e-148	516.00
IUUC-Pca-100498	Procavia capensis	52.15	9.00e-49	187.00
IUUC-Pva-102599	Pteropus vampyrus	41.89	4.00e-147	514.00
IUUC-Rno-105776	Rattus norvegicus	41.35	8.00e-147	513.00
IUUC-Sha-106699	Sarcophilus harrisii	41.98	2.00e-146	511.00
IUUC-Sar-113621	Sorex araneus	41.18	3.00e-145	507.00
IUUC-Ssc-115742	Sus scrofa	41.89	1.00e-147	515.00
IUUC-Tgu-116490	Taeniopygia guttata	42.71	7.00e-147	513.00
IUUC-Tru-117679	Takifugu rubripes	41.77	3.00e-155	541.00
IUUC-Tsy-119607	Tarsius syrichta	41.80	5.00e-135	473.00
IUUC-Tni-120376	Tetraodon nigroviridis	44.03	7.00e-154	536.00
IUUC-Tbe-127348	Tupaia belangeri	41.16	3.00e-71	261.00
IUUC-Ttr-128786	Tursiops truncatus	49.53	6.00e-127	447.00
IUUC-Vpa-130180	Vicugna pacos	38.16	4.00e-93	334.00
IUUC-Xtr-132631	Xenopus tropicalis	40.87	2.00e-148	518.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence