iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089645

Ensembl Protein ID

ENSOARP00000017185.1

UniProt Accession

W5Q397; W5Q397_SHEEP

Genbank Protein ID

ENSOARP00000017185

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01036900

Gene Name

KLHL2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000016002.1	ENSOART00000017426.1	ENSOARP00000017185.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.90e-21	75.8	55	122
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	7.20e-11	41.2	155	184

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv++v ++ e++ah++vLaa+S++F+a+f++e++es+  ++v ik+v+   +r l++++Yt +++ +e
   Q: 55   CDVTIVAEDMEISAHRVVLAACSPYFHAMFTGEMSESR-AKRVRIKEVDGWTLRMLIDYVYTAEIQVTE 122
           8*************************************.*************************99765 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhF 31
            Nclgi++fAd++ c+dL  +a++++++hF
   Q: 155  VNCLGIRAFADMHACTDLLNKANTYAEQHF 184
           6****************************9 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

EPVPVLVSCT NQGHQKPLDS KDDNTEKHCP VTVNPWHMKK AFKVMNELRS QNLLCDVTIV 60
AEDMEISAHR VVLAACSPYF HAMFTGEMSE SRAKRVRIKE VDGWTLRMLI DYVYTAEIQV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAACCAGTTC CTGTCTTGGT TTGTAAATAG GCCTACTGCA GAATGTAAAA AGCAGGTTAA 60
TTTCCAACAG GGAAGATCCT TTCTCAGCAT TTCTTTTGAA GGTATCTGGA GAAGGCAATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002378	Ailuropoda melanoleuca	98.31	0.00e+00	1167.00
IUUC-Apl-003260	Anas platyrhynchos	92.98	0.00e+00	1100.00
IUUC-Aca-005143	Anolis carolinensis	88.23	0.00e+00	1087.00
IUUC-Cja-018942	Callithrix jacchus	98.30	0.00e+00	1163.00
IUUC-Cfa-020886	Canis familiaris	99.32	0.00e+00	1167.00
IUUC-Cpo-022543	Cavia porcellus	98.14	0.00e+00	1168.00
IUUC-Csa-023088	Chlorocebus sabaeus	97.80	0.00e+00	1162.00
IUUC-Dre-028082	Danio rerio	81.68	0.00e+00	974.00
IUUC-Dno-029873	Dasypus novemcinctus	96.11	0.00e+00	1141.00
IUUC-Dor-030460	Dipodomys ordii	79.28	0.00e+00	858.00
IUUC-Dse-031229	Dothistroma septosporum	37.14	4.00e-08	51.20
IUUC-Dme-032172	Drosophila melanogaster	61.72	0.00e+00	670.00
IUUC-Eca-033798	Equus caballus	98.63	0.00e+00	1160.00
IUUC-Eeu-034824	Erinaceus europaeus	91.16	0.00e+00	967.00
IUUC-Fca-036455	Felis catus	99.32	0.00e+00	1167.00
IUUC-Fal-037293	Ficedula albicollis	92.79	0.00e+00	1043.00
IUUC-Gmo-038811	Gadus morhua	78.85	0.00e+00	875.00
IUUC-Gga-040805	Gallus gallus	92.47	0.00e+00	1096.00
IUUC-Gac-041979	Gasterosteus aculeatus	81.29	0.00e+00	880.00
IUUC-Ggo-044620	Gorilla gorilla	94.01	0.00e+00	1100.00
IUUC-Hsa-046265	Homo sapiens	98.14	0.00e+00	1166.00
IUUC-Lch-049939	Latimeria chalumnae	83.87	0.00e+00	981.00
IUUC-Loc-052780	Lepisosteus oculatus	86.64	0.00e+00	1029.00
IUUC-Laf-053800	Loxodonta africana	97.96	0.00e+00	1160.00
IUUC-Mcc-055732	Macaca mulatta	97.77	0.00e+00	1147.00
IUUC-Meu-056011	Macropus eugenii	95.76	0.00e+00	1048.00
IUUC-Mmr-061067	Microcebus murinus	96.95	0.00e+00	1150.00
IUUC-Mdo-062977	Monodelphis domestica	94.69	0.00e+00	1123.00
IUUC-Mmu-064035	Mus musculus	97.26	0.00e+00	1144.00
IUUC-Mpu-066726	Mustela putorius furo	99.14	0.00e+00	1165.00
IUUC-Mlu-067020	Myotis lucifugus	98.63	0.00e+00	1159.00
IUUC-Nle-069456	Nomascus leucogenys	98.64	0.00e+00	1167.00
IUUC-Opr-071130	Ochotona princeps	88.87	0.00e+00	1018.00
IUUC-Ont-072219	Oreochromis niloticus	82.87	0.00e+00	931.00
IUUC-Oan-073699	Ornithorhynchus anatinus	94.49	0.00e+00	959.00
IUUC-Ocu-074045	Oryctolagus cuniculus	97.80	0.00e+00	1164.00
IUUC-Oga-088494	Otolemur garnettii	98.63	0.00e+00	1160.00
IUUC-Ptr-091063	Pan troglodytes	98.47	0.00e+00	1165.00
IUUC-Pan-092273	Papio anubis	97.75	0.00e+00	952.00
IUUC-Psi-093946	Pelodiscus sinensis	91.06	0.00e+00	1108.00
IUUC-Pma-094177	Petromyzon marinus	74.51	0.00e+00	795.00
IUUC-Pfo-096817	Poecilia formosa	81.82	0.00e+00	942.00
IUUC-Pab-097768	Pongo abelii	97.97	0.00e+00	1164.00
IUUC-Pca-100607	Procavia capensis	81.12	0.00e+00	826.00
IUUC-Pva-102218	Pteropus vampyrus	92.23	0.00e+00	1081.00
IUUC-Rno-105250	Rattus norvegicus	97.47	0.00e+00	1158.00
IUUC-Sar-113249	Sorex araneus	98.43	0.00e+00	1139.00
IUUC-Ssc-115423	Sus scrofa	99.49	0.00e+00	1167.00
IUUC-Tgu-117050	Taeniopygia guttata	91.45	0.00e+00	1084.00
IUUC-Tru-118239	Takifugu rubripes	81.68	0.00e+00	969.00
IUUC-Tsy-119377	Tarsius syrichta	84.76	0.00e+00	1000.00
IUUC-Tni-120122	Tetraodon nigroviridis	80.83	0.00e+00	877.00
IUUC-Vpa-130707	Vicugna pacos	95.92	0.00e+00	883.00
IUUC-Xtr-132035	Xenopus tropicalis	85.86	0.00e+00	1050.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence