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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Cel-018109
UUCD1 version UUC-CaE-00496
Ensembl Protein ID Y66D12A.17
UniProt Accession Q95Q00; SUCH1_CAEEL
Genbank Protein ID CAC70137.2
Protein Name Suppressor of spindle checkpoint defect 1
Genbank Nucleotide ID AL161712
Gene Name such-1; som-2; Y66D12A.17
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00013443 Y66D12A.17 Y66D12A.17
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNARAID2
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 adaptor/Cullin RING/APC_C/APC_C 21.04 2.00e-04 45.80 IUUC-Hsa-047014
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Caenorhabditis elegans
Functional Description
(View)

Functional Description


     Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle (By similarity). The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins (By similarity). Required for the metaphase to anaphase transition in meiosis (PubMed:17237515, PubMed:20944012). Plays a role in the segregation of DNA and centrioles during meiosis in male germ cells (PubMed:20944014).
 Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle (By similarity). The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins (By similarity). Required for the metaphase to anaphase transition in meiosis (PubMed:17237515, PubMed:20944012). Plays a role in the segregation of DNA and centrioles during meiosis in male germ cells (PubMed:20944014).
Protein Sequence
(Fasta)
MPPKKAQTRR IVSLDSLFGH TLLNITGEPV TPTKIAIFQL IRTLFHAHFG VGAVPSLKPF 60
DKDEKTRVFT VLYGLIIMKS EISYDDFRCI VRILNDGLGR SIYYRFVTSM EKLAHGEDQI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cel-018109|E3,APC_C|Caenorhabditis elegans
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AATGCCTCCG AAAAAAGCGC AAACTCGACG AATCGTCAGT CTGGATTCAC TTTTTGGCCA 60
TACTCTACTG AATATCACCG GCGAACCTGT GACACCAACG AAAATCGCCA TTTTTCAACT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cel-018109|E3,APC_C|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0469--Meiosis
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
Interpro

IPR011990--TPR-like_helical_dom
Gene Ontology

GO:0051301--P:cell division
GO:0051321--P:meiotic cell cycle
GO:0007067--P:mitotic nuclear division
GO:0007275--P:multicellular organism development
GO:0016567--P:protein ubiquitination
KEGG cel:CELE_Y66D12A.17
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000646 Aegilops tauschii 40.62 1.80e-01 30.40
IUUC-Aml-001228 Ailuropoda melanoleuca 20.44 3.00e-09 56.20
IUUC-Apl-003267 Anas platyrhynchos 20.89 1.00e-05 43.90
IUUC-Bta-013451 Bos taurus 20.84 2.00e-07 50.10
IUUC-Cja-019568 Callithrix jacchus 20.44 4.00e-09 55.50
IUUC-Cfa-020050 Canis familiaris 20.31 1.00e-08 53.50
IUUC-Cpo-021705 Cavia porcellus 20.54 4.00e-08 52.00
IUUC-Csa-023099 Chlorocebus sabaeus 20.44 2.00e-07 50.10
IUUC-Cho-024968 Choloepus hoffmanni 28.89 1.00e-03 37.40
IUUC-Dre-028446 Danio rerio 24.07 4.00e-03 35.80
IUUC-Dno-029248 Dasypus novemcinctus 20.00 1.00e-07 50.80
IUUC-Dor-030713 Dipodomys ordii 28.70 3.00e-04 39.30
IUUC-Ete-032483 Echinops telfairi 20.32 3.00e-08 52.80
IUUC-Eca-033381 Equus caballus 20.70 1.00e-07 50.80
IUUC-Fca-035995 Felis catus 21.38 8.00e-05 40.80
IUUC-Fal-037344 Ficedula albicollis 30.56 2.00e-04 40.40
IUUC-Gga-040306 Gallus gallus 20.89 1.00e-04 40.40
IUUC-Gac-042229 Gasterosteus aculeatus 25.23 9.00e-03 34.70
IUUC-Ggo-045040 Gorilla gorilla 21.04 3.00e-09 55.80
IUUC-Hsa-047014 Homo sapiens 21.04 3.00e-09 55.80
IUUC-Hvu-047209 Hordeum vulgare 40.62 2.00e-01 30.00
IUUC-Itr-047936 Ictidomys tridecemlineatus 31.48 6.00e-06 43.90
IUUC-Lch-049595 Latimeria chalumnae 22.69 4.00e-03 35.80
IUUC-Lpe-051682 Leersia perrieri 40.62 1.60e-01 30.40
IUUC-Loc-052640 Lepisosteus oculatus 20.50 1.60e-01 30.40
IUUC-Laf-054391 Loxodonta africana 20.12 9.00e-08 51.20
IUUC-Mcc-055384 Macaca mulatta 21.04 3.00e-09 55.80
IUUC-Meu-056410 Macropus eugenii 33.33 1.10e+00 27.30
IUUC-Mga-059991 Meleagris gallopavo 19.68 4.00e-04 38.90
IUUC-Mmr-060939 Microcebus murinus 21.85 4.00e-06 45.40
IUUC-Mdo-062775 Monodelphis domestica 21.56 2.00e-05 43.10
IUUC-Mmu-063110 Mus musculus 20.24 6.00e-08 51.60
IUUC-Mpu-066382 Mustela putorius furo 20.52 3.00e-08 52.80
IUUC-Mlu-067724 Myotis lucifugus 28.21 1.00e-03 37.40
IUUC-Nle-069022 Nomascus leucogenys 21.04 3.00e-09 55.80
IUUC-Opr-070727 Ochotona princeps 21.98 1.00e-07 50.40
IUUC-Ont-071409 Oreochromis niloticus 25.17 9.00e-03 34.30
IUUC-Oan-073732 Ornithorhynchus anatinus 21.23 5.70e-02 30.80
IUUC-Oba-075329 Oryza barthii 40.62 1.70e-01 30.40
IUUC-Obr-076176 Oryza brachyantha 40.62 1.70e-01 30.40
IUUC-Ogl-076949 Oryza glaberrima 40.62 1.70e-01 30.40
IUUC-Ogu-078835 Oryza glumaepatula 40.62 1.70e-01 30.40
IUUC-Oin-079783 Oryza indica 40.62 1.60e-01 30.40
IUUC-Olo-080921 Oryza longistaminata 40.62 2.30e-01 30.40
IUUC-Ome-081983 Oryza meridionalis 40.62 2.60e-01 30.40
IUUC-Oni-082649 Oryza nivara 40.62 1.60e-01 30.40
IUUC-Opu-083962 Oryza punctata 40.62 1.60e-01 30.40
IUUC-Oru-085221 Oryza rufipogon 40.62 1.70e-01 30.40
IUUC-Osa-086035 Oryza sativa 40.62 1.70e-01 30.40
IUUC-Ola-087386 Oryzias latipes 25.00 7.00e-03 35.00
IUUC-Oga-089166 Otolemur garnettii 19.68 3.00e-06 46.20
IUUC-Oar-090437 Ovis aries 20.76 6.00e-06 45.10
IUUC-Ptr-090917 Pan troglodytes 21.04 3.00e-09 55.80
IUUC-Pan-091739 Papio anubis 21.98 2.00e-07 49.70
IUUC-Psi-093776 Pelodiscus sinensis 20.79 8.00e-04 37.70
IUUC-Ppa-095707 Physcomitrella patens 37.50 9.00e-01 28.10
IUUC-Pfo-096997 Poecilia formosa 25.00 4.00e-03 35.40
IUUC-Pab-098518 Pongo abelii 21.04 3.00e-09 55.80
IUUC-Pca-100400 Procavia capensis 31.48 7.00e-06 44.70
IUUC-Pva-103252 Pteropus vampyrus 21.43 1.00e-07 50.40
IUUC-Rno-104876 Rattus norvegicus 20.24 1.00e-07 50.40
IUUC-Sha-107267 Sarcophilus harrisii 22.14 2.00e-06 46.60
IUUC-Sit-110705 Setaria italica 43.75 5.90e-02 32.00
IUUC-Sar-113485 Sorex araneus 31.48 3.00e-05 42.70
IUUC-Sbi-114673 Sorghum bicolor 43.75 6.40e-02 32.00
IUUC-Ssc-115301 Sus scrofa 20.90 8.00e-08 51.20
IUUC-Tgu-116928 Taeniopygia guttata 21.13 2.00e-05 43.10
IUUC-Tru-117756 Takifugu rubripes 24.54 7.00e-03 35.00
IUUC-Tsy-119155 Tarsius syrichta 22.60 2.00e-05 43.10
IUUC-Tni-120285 Tetraodon nigroviridis 27.65 1.00e-03 37.40
IUUC-Tvi-122315 Trichoderma virens 28.05 1.00e-01 30.40
IUUC-Tae-125147 Triticum aestivum 40.62 1.80e-01 30.40
IUUC-Tur-126507 Triticum urartu 40.62 1.90e-01 30.40
IUUC-Tbe-127653 Tupaia belangeri 33.33 1.00e+00 27.70
IUUC-Ttr-129200 Tursiops truncatus 20.20 7.00e-06 44.70
IUUC-Vpa-130494 Vicugna pacos 29.75 8.00e-06 44.70
IUUC-Xtr-132765 Xenopus tropicalis 26.51 1.00e-04 40.40
IUUC-Xma-133195 Xiphophorus maculatus 24.48 1.70e-02 33.10
Created Date 25-Jun-2017

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