iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033712

Ensembl Protein ID

ENSECAP00000000552.1

UniProt Accession

F7DSM8; F7DSM8_HORSE

Protein Name

Uncharacterized protein

Gene Name

PPARA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000000484.1	ENSECAT00000000699.1	ENSECAP00000000552.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	95.30	0.00e+00	881.00	IUUC-Hsa-046893

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Equus caballus

Protein Sequence
(Fasta)

VAMVDTESPI CPLSPLEADD LDSPLSEGFL QEMGNIQELS QSIGEDSCGS FSFTEYQYLG 60
SGPGSDGSVI TDTLSPASSP SSVTYPVVPG STDESSSTAL NIECRICGDK ASGYHYGVHA 120

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Nucleotide Sequence
(Fasta)

CGTCTGTCGC GATGGTGGAC ACGGAAAGCC CGATTTGCCC TCTCTCCCCT CTCGAGGCTG 60
ATGATCTGGA CAGCCCGTTA TCGGAAGGAT TCCTTCAAGA AATGGGAAAC ATCCAAGAGC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003076--1Cnucl_rcpt_A
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01289--PROXISOMPAAR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008144--F:drug binding
GO:0008289--F:lipid binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001190--F:transcriptional activator activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0070166--P:enamel mineralization
GO:0008544--P:epidermis development
GO:0006631--P:fatty acid metabolic process
GO:0032099--P:negative regulation of appetite
GO:0010887--P:negative regulation of cholesterol storage
GO:0050728--P:negative regulation of inflammatory response
GO:1903038--P:negative regulation of leukocyte cell-cell adhesion
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:1902894--P:negative regulation of pri-miRNA transcription from RNA polymerase II promoter
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0046321--P:positive regulation of fatty acid oxidation
GO:0045722--P:positive regulation of gluconeogenesis
GO:0072366--P:regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
GO:0042752--P:regulation of circadian rhythm
GO:0072363--P:regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
GO:0072369--P:regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002222	Ailuropoda melanoleuca	93.64	0.00e+00	924.00
IUUC-Apl-003330	Anas platyrhynchos	87.29	0.00e+00	836.00
IUUC-Aca-004598	Anolis carolinensis	85.32	0.00e+00	825.00
IUUC-Acl-008339	Aspergillus clavatus	45.45	1.40e-01	29.30
IUUC-Ame-011508	Astyanax mexicanus	73.83	0.00e+00	701.00
IUUC-Bta-012621	Bos taurus	95.30	0.00e+00	895.00
IUUC-Cja-019688	Callithrix jacchus	94.66	0.00e+00	886.00
IUUC-Cfa-020859	Canis familiaris	94.66	0.00e+00	927.00
IUUC-Cpo-021607	Cavia porcellus	88.03	0.00e+00	831.00
IUUC-Csa-023313	Chlorocebus sabaeus	94.66	0.00e+00	882.00
IUUC-Cho-024741	Choloepus hoffmanni	82.91	0.00e+00	749.00
IUUC-Cgl-026615	Colletotrichum gloeosporioides	34.48	2.70e-01	27.70
IUUC-Dre-027446	Danio rerio	72.98	0.00e+00	691.00
IUUC-Dno-029173	Dasypus novemcinctus	91.06	0.00e+00	861.00
IUUC-Dor-030581	Dipodomys ordii	90.15	0.00e+00	811.00
IUUC-Dme-031794	Drosophila melanogaster	33.90	1.00e-54	208.00
IUUC-Ete-032330	Echinops telfairi	90.60	0.00e+00	874.00
IUUC-Fca-036555	Felis catus	95.11	0.00e+00	929.00
IUUC-Fal-036677	Ficedula albicollis	87.82	0.00e+00	837.00
IUUC-Gmo-039240	Gadus morhua	81.33	0.00e+00	642.00
IUUC-Gga-040473	Gallus gallus	87.82	0.00e+00	840.00
IUUC-Gac-041872	Gasterosteus aculeatus	72.30	0.00e+00	704.00
IUUC-Ggo-045226	Gorilla gorilla	95.30	0.00e+00	890.00
IUUC-Hsa-046893	Homo sapiens	95.30	0.00e+00	890.00
IUUC-Itr-048952	Ictidomys tridecemlineatus	91.67	0.00e+00	862.00
IUUC-Lch-050116	Latimeria chalumnae	78.85	0.00e+00	760.00
IUUC-Loc-052131	Lepisosteus oculatus	83.25	0.00e+00	689.00
IUUC-Laf-054323	Loxodonta africana	95.09	0.00e+00	892.00
IUUC-Mcc-054841	Macaca mulatta	95.11	0.00e+00	888.00
IUUC-Meu-056833	Macropus eugenii	81.41	0.00e+00	748.00
IUUC-Mtr-058471	Medicago truncatula	29.82	1.80e-01	30.00
IUUC-Mga-059995	Meleagris gallopavo	79.03	0.00e+00	742.00
IUUC-Mmr-060576	Microcebus murinus	64.91	4.00e-147	514.00
IUUC-Mdo-061954	Monodelphis domestica	87.96	0.00e+00	787.00
IUUC-Mmu-064295	Mus musculus	90.81	0.00e+00	831.00
IUUC-Mpu-066216	Mustela putorius furo	94.87	0.00e+00	928.00
IUUC-Mlu-067978	Myotis lucifugus	62.91	5.00e-152	530.00
IUUC-Nle-069970	Nomascus leucogenys	95.09	0.00e+00	887.00
IUUC-Opr-070630	Ochotona princeps	62.46	1.00e-117	416.00
IUUC-Ont-071594	Oreochromis niloticus	73.15	0.00e+00	695.00
IUUC-Oan-073501	Ornithorhynchus anatinus	91.44	0.00e+00	767.00
IUUC-Ocu-074634	Oryctolagus cuniculus	83.70	0.00e+00	823.00
IUUC-Oni-082926	Oryza nivara	29.41	1.70e-02	30.00
IUUC-Ola-086585	Oryzias latipes	79.89	0.00e+00	638.00
IUUC-Oga-088738	Otolemur garnettii	95.74	0.00e+00	887.00
IUUC-Oar-090453	Ovis aries	94.66	0.00e+00	893.00
IUUC-Ptr-091518	Pan troglodytes	95.09	0.00e+00	884.00
IUUC-Pan-092006	Papio anubis	95.09	0.00e+00	884.00
IUUC-Psi-093352	Pelodiscus sinensis	86.44	0.00e+00	836.00
IUUC-Pfo-096060	Poecilia formosa	72.30	0.00e+00	687.00
IUUC-Pab-098602	Pongo abelii	88.82	0.00e+00	790.00
IUUC-Pca-100861	Procavia capensis	63.41	2.00e-146	512.00
IUUC-Pva-102175	Pteropus vampyrus	89.32	0.00e+00	863.00
IUUC-Rno-105283	Rattus norvegicus	91.03	0.00e+00	831.00
IUUC-Sce-106436	Saccharomyces cerevisiae	29.03	1.00e-02	31.60
IUUC-Sha-106560	Sarcophilus harrisii	91.67	0.00e+00	867.00
IUUC-Smo-109075	Selaginella moellendorffii	30.00	9.10e-02	30.00
IUUC-Sar-112996	Sorex araneus	52.88	7.00e-113	400.00
IUUC-Ssc-115266	Sus scrofa	94.44	0.00e+00	928.00
IUUC-Tgu-116778	Taeniopygia guttata	87.45	0.00e+00	838.00
IUUC-Tru-118436	Takifugu rubripes	71.58	0.00e+00	694.00
IUUC-Tsy-119642	Tarsius syrichta	81.62	0.00e+00	736.00
IUUC-Tni-119859	Tetraodon nigroviridis	71.58	0.00e+00	690.00
IUUC-Tvi-122624	Trichoderma virens	33.33	4.70e-02	30.40
IUUC-Tbe-127464	Tupaia belangeri	92.95	0.00e+00	904.00
IUUC-Ttr-129307	Tursiops truncatus	90.83	0.00e+00	838.00
IUUC-Vpa-130378	Vicugna pacos	63.33	5.00e-116	410.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence