iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054112

Ensembl Protein ID

ENSLAFP00000027190.1

UniProt Accession

G3UH82; G3UH82_LOXAF

Protein Name

Histone-lysine N-methyltransferase

Gene Name

WHSC1L1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000014727.4	ENSLAFT00000025974.1	ENSLAFP00000027190.1
ENSLAFG00000014727.4	ENSLAFT00000026407.1	ENSLAFP00000018784.1
ENSLAFG00000014727.4	ENSLAFT00000014730.4	ENSLAFP00000012330.4
ENSLAFG00000014727.4	ENSLAFT00000028853.1	ENSLAFP00000021891.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.20e-09	38.5	702	746

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek.CrewfHpaClklsveeelpnsekwiCpkCr 52
           +vC +C+++g+   sl+ Ce  C++ fH +Cl+l+   +lp+ + +iC +C+
   Q: 702  AVCQICESTGD---SLIPCEGeCCKHFHLECLGLA---SLPDGK-FICMECQ 746
           79********9...5********************...*****7.******7 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MDFSFSFMQG IMGNTIQQPP QLIDSANIRQ EDAFDNNSDI VEDGGQTQYE ATLQQGFQYQ 60
PTTEDLPPLT NGYPPSISMY ETQTKYQPYN QYPNGSANGF GAVRNFTPTD YYHTEIPNTR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATTTCT CTTTCTCTTT CATGCAAGGG ATCATGGGAA ACACAATTCA GCAACCACCT 60
CAACTCATTG ACTCCGCTAA CATCCGTCAG GAGGATGCCT TTGATAACAA CAGTGACATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006560--AWS_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51215--AWS
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00855--PWWP
PF00856--SET

SMART

SM00570--AWS
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000310	Aegilops tauschii	29.41	6.00e-12	66.20
IUUC-Aml-001809	Ailuropoda melanoleuca	93.82	0.00e+00	1746.00
IUUC-Apl-004027	Anas platyrhynchos	76.82	0.00e+00	2034.00
IUUC-Aca-005380	Anolis carolinensis	82.39	0.00e+00	2202.00
IUUC-Ame-011234	Astyanax mexicanus	59.56	0.00e+00	1440.00
IUUC-Bta-013575	Bos taurus	91.28	0.00e+00	2597.00
IUUC-Cja-020013	Callithrix jacchus	95.22	0.00e+00	2738.00
IUUC-Cfa-021060	Canis familiaris	94.74	0.00e+00	2649.00
IUUC-Cpo-021834	Cavia porcellus	92.24	0.00e+00	2538.00
IUUC-Csa-023370	Chlorocebus sabaeus	95.08	0.00e+00	2734.00
IUUC-Cho-025058	Choloepus hoffmanni	86.75	0.00e+00	1111.00
IUUC-Dre-027664	Danio rerio	59.24	0.00e+00	1466.00
IUUC-Dno-029302	Dasypus novemcinctus	92.94	0.00e+00	2601.00
IUUC-Eca-033626	Equus caballus	92.87	0.00e+00	2627.00
IUUC-Fca-035556	Felis catus	95.08	0.00e+00	2691.00
IUUC-Fal-037101	Ficedula albicollis	81.63	0.00e+00	2196.00
IUUC-Gmo-038901	Gadus morhua	55.61	0.00e+00	1526.00
IUUC-Gga-040366	Gallus gallus	82.13	0.00e+00	2154.00
IUUC-Gac-042047	Gasterosteus aculeatus	60.46	0.00e+00	1347.00
IUUC-Ggo-044695	Gorilla gorilla	91.23	0.00e+00	2597.00
IUUC-Hsa-046080	Homo sapiens	94.66	0.00e+00	2730.00
IUUC-Itr-048622	Ictidomys tridecemlineatus	94.11	0.00e+00	2660.00
IUUC-Lch-050544	Latimeria chalumnae	70.43	0.00e+00	1626.00
IUUC-Loc-052656	Lepisosteus oculatus	63.96	0.00e+00	1590.00
IUUC-Mcc-054956	Macaca mulatta	95.08	0.00e+00	2730.00
IUUC-Meu-056051	Macropus eugenii	85.92	0.00e+00	1208.00
IUUC-Mga-060139	Meleagris gallopavo	84.50	0.00e+00	2236.00
IUUC-Mmr-060789	Microcebus murinus	93.49	0.00e+00	2685.00
IUUC-Mdo-062908	Monodelphis domestica	89.68	0.00e+00	2498.00
IUUC-Mmu-063165	Mus musculus	84.72	0.00e+00	2357.00
IUUC-Mpu-066002	Mustela putorius furo	94.73	0.00e+00	2682.00
IUUC-Nle-069417	Nomascus leucogenys	94.36	0.00e+00	2545.00
IUUC-Ont-071900	Oreochromis niloticus	58.33	0.00e+00	1615.00
IUUC-Oan-072857	Ornithorhynchus anatinus	89.13	0.00e+00	2506.00
IUUC-Ocu-073809	Oryctolagus cuniculus	93.69	0.00e+00	2639.00
IUUC-Ogu-078030	Oryza glumaepatula	29.03	4.00e-13	68.60
IUUC-Ola-087085	Oryzias latipes	58.18	0.00e+00	1582.00
IUUC-Oga-088289	Otolemur garnettii	93.00	0.00e+00	2602.00
IUUC-Oar-089398	Ovis aries	92.04	0.00e+00	2609.00
IUUC-Ptr-090510	Pan troglodytes	94.46	0.00e+00	2722.00
IUUC-Pan-092291	Papio anubis	95.15	0.00e+00	2739.00
IUUC-Psi-093547	Pelodiscus sinensis	86.19	0.00e+00	2323.00
IUUC-Pma-094747	Petromyzon marinus	48.41	0.00e+00	1065.00
IUUC-Pfo-096669	Poecilia formosa	58.31	0.00e+00	1585.00
IUUC-Pab-097727	Pongo abelii	95.01	0.00e+00	2713.00
IUUC-Pca-100474	Procavia capensis	88.19	0.00e+00	2369.00
IUUC-Pva-102539	Pteropus vampyrus	92.80	0.00e+00	2363.00
IUUC-Rno-105685	Rattus norvegicus	88.55	0.00e+00	2414.00
IUUC-Sha-107287	Sarcophilus harrisii	90.24	0.00e+00	2489.00
IUUC-Sar-113547	Sorex araneus	87.66	0.00e+00	2501.00
IUUC-Ssc-116208	Sus scrofa	94.66	0.00e+00	2729.00
IUUC-Tgu-117006	Taeniopygia guttata	84.25	0.00e+00	2288.00
IUUC-Tru-118375	Takifugu rubripes	58.90	0.00e+00	1611.00
IUUC-Tsy-119323	Tarsius syrichta	94.46	0.00e+00	2650.00
IUUC-Tni-120509	Tetraodon nigroviridis	59.27	0.00e+00	1617.00
IUUC-Tae-124687	Triticum aestivum	29.41	6.00e-12	65.90
IUUC-Ttr-128240	Tursiops truncatus	91.89	0.00e+00	2560.00
IUUC-Vpa-130666	Vicugna pacos	93.42	0.00e+00	2607.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence