iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052558

Ensembl Protein ID

ENSLOCP00000015254.1

UniProt Accession

W5N3P5; W5N3P5_LEPOC

Genbank Protein ID

ENSLOCP00000015254

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01000342

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000012387.1	ENSLOCT00000015283.1	ENSLOCP00000015254.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-34	116.3	521	556
UBD/Beta-Prp	6.50e-52	176.7	334	627

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           H+++ +c  + +  + +v+GsdD t+ vWD+ tg++
   Q: 521  HSAPLSCALYnPFfKQVVTGSDDSTVAVWDVETGTK 556
           88888887665335779**************99975 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseDrtikvw.dlstgkcvht 89
           + + g h + i+ +++ ++++l++t+s ++++ v  ++ + + +s+  + +++vt+ +f ++ ++lvtg+ D+t+++w  + t+ +v t
   Q: 334  QLIPGVHREAIRRICYERSGDLIITSSGSSSTSVVIMDAPRKKKSYtWKINKGVTCFDFCKSLNLLVTGGVDHTVRLWnQYVTSRPVAT 422
           6677889999********************9999988888888888788899**************************8899******* PP
   S: 90   lkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee............................................... 131
           l+gh   vl++ +++    + s s+d +++vwd+++  cl++                                               
   Q: 423  LQGHYMAVLDVVIYEPLGQIFSYSKDAVLKVWDISSLCCLRTlllkfpcvqagravehgdfpfllltsaphvllvscgdylallrlqsg 511
           ***************9************************************************************************* PP
   S: 132  .....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltggh.tdsvyslsfdsngkelvsgsldgtvklwdlqtgec 214
                 l  h++  +c+ ++p+ + +v+Gs+D+tv +Wd++tg+   +l+  h ++ ++++++d ++++l++g+++g +k+w++q+g+ 
   Q: 512  gaegdRLLTHSAPLSCALYNPFFKQVVTGSDDSTVAVWDVETGTKCLQLSNVHgQEEITCMALDTTQRRLITGARNGAIKVWNIQNGHN 600
           *****9999**********************************99999977672568******************************** PP
   S: 215  vrtlng.htdnvksvrfspnderlvsgs 241
           +++l++  ++ v+ v  ++++++l + +
   Q: 601  LHKLEAiAEAEVTGVICFQDNKLLTV-G 627
           ******77899999999966665544.3 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MCATRDWDSG IWEIYEKEIP VTITGFDQEQ NTGLEEELQL EHLQWLKEAF ASHVPRDPRS 60
GEVGAGWKAG RGWRSSRGPK QQAGSMSLEE FQSALGTMLG SERWASQMEL LFNKVDTSCD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCACTGAC AGTGAGCACA CAGAGAAGAG TGTAATAACC AGGTCATACA GTATAATGTC 60
AGAGCTCCTG GAGAAAGCAG AAAGACTGTT TGGGAGTAGA CAGTAAGAGC TGATGTTATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13833--EF-hand_8
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005509--F:calcium ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cin-025187	Ciona intestinalis	44.53	0.00e+00	632.00
IUUC-Dre-027920	Danio rerio	46.47	0.00e+00	658.00
IUUC-Gmo-039225	Gadus morhua	46.64	1.00e-119	422.00
IUUC-Lch-050151	Latimeria chalumnae	64.34	0.00e+00	894.00
IUUC-Mdo-062601	Monodelphis domestica	48.09	0.00e+00	711.00
IUUC-Ont-072106	Oreochromis niloticus	45.11	0.00e+00	710.00
IUUC-Tru-117878	Takifugu rubripes	45.09	3.00e-117	415.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence