iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ola-086857

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

BAAF04017042

Gene Name

USP50

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000003094.1	ENSORLT00000003855.1	ENSORLP00000003854.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-76	258.1	21	359

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.......kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeae 82
           +Gl+N gN+CY+N+vLQcL ++ +l e+ll+          +++  +n+  +k ++++ + +l+e++w ++ ++ sp e+ +al+++ +
   Q: 21   CGLENSGNSCYLNAVLQCLCATVPLVEQLLHwdtrkglARYHHFILNNSGRSKCRVSEVFVHLLEKMWMGSGSSCSPLEVRSALCSVLP 109
           7*******************************9999996666666777899************************************** PP
   S: 83   efsgyeqqDaqEflaflldqleeelkk......eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssr 165
           +f++ +qqDaqE+l  ll++l+++++k       +++   ++ + +  +  ++++ k  + +++l+++lF+gql+  ++c +c+++   
   Q: 110  QFNNDSQQDAQELLLLLLNTLHDDFNKvllnmfGRSTLCAQTDGVSGVKPARMEQIKGCSPHSNLVTRLFEGQLSYMCICMHCHHQAHN 198
           *************************88777777666666666666666677778899999999************************** PP
   S: 166  eepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkve 254
           ++ f+ lslpvp+ +   k s+qdcL+ f+k+  l+g ++  c+ c  k+e+   + +++ Pe+L+lhLkRf   +++ks+ k+ ++v 
   Q: 199  TQAFTVLSLPVPKGNI--KCSIQDCLALFFKQTVLTGGEQAMCSVCGLKRETAIVTCVDRTPEILVLHLKRF--GSKGKSQVKLRTNVL 283
           ************8774..46****************************************************..88899********** PP
   S: 255  fpleLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfY 335
           f  +Ldls+f++       ++ +Y L+avv+H+G l+ GHY+a+++n+  + W +fdD  V ev+e++v++    +aY+lfY
   Q: 284  FFMKLDLSQFLSGLVP---NESSYHLYAVVNHTGHLNMGHYTALCYNSLAQtWHCFDDAAVCEVQEDRVQS---PNAYLLFY 359
           ************9444...489*************************88778*******************...******** PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MNVHFVPTSQ KEKKCRRPGV CGLENSGNSC YLNAVLQCLC ATVPLVEQLL HWDTRKGLAR 60
YHHFILNNSG RSKCRVSEVF VHLLEKMWMG SGSSCSPLEV RSALCSVLPQ FNNDSQQDAQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATGTTC ACTTTGTCCC AACGTCTCAA AAGGAGGTGA GGAACCTGAC ATCATCTGCA 60
TCTCTGCCAA TCTCACCTCA GCATCTATCA TCTAAGGACC CAGAGTCCAC ATTTTCCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ete-032570	Echinops telfairi	31.60	4.00e-31	128.00
IUUC-Gac-042261	Gasterosteus aculeatus	59.54	7.00e-112	396.00
IUUC-Loc-051880	Lepisosteus oculatus	47.11	1.00e-73	270.00
IUUC-Ont-072200	Oreochromis niloticus	64.64	1.00e-114	406.00
IUUC-Pfo-096718	Poecilia formosa	53.06	2.00e-93	336.00
IUUC-Tru-118574	Takifugu rubripes	62.43	2.00e-110	392.00
IUUC-Tni-120385	Tetraodon nigroviridis	60.70	5.00e-98	350.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence