iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001574

Ensembl Protein ID

ENSAMEP00000001612.1

UniProt Accession

G1L402; G1L402_AILME

Genbank Protein ID

ENSAMEP00000001612

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01002469

Gene Name

CD2AP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000001509.1	ENSAMET00000001673.1	ENSAMEP00000001612.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.70e-66	218.2	270	329

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +ke++++l+ ye++n+deL++k+G+++++i+ke+ ++gW+kg  el+gk+G+fP+nF  +++
   Q: 270  AKEYCRTLFAYEGTNEDELSFKEGEIIYLISKETGEAGWWKG--ELNGKEGVFPDNFAIQIN 329
           689***************************************..9************99887 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

LVDYIVEYDY DAVHDDELTI RVGEIIRNVK KLQEEGWLEG ELNGRRGMFP DNFVKEIKRD 60
TESKDDSLPI KRERHGNVAS LVQRISTYGL PVGGIQPHPQ TKNIKKKTKK RQCKVLFEYI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAGTTGACT ATATTGTGGA GTATGACTAC GATGCTGTAC ATGACGATGA ATTAACTATT 60
CGAGTTGGTG AAATCATCAG GAATGTGAAA AAACTGCAGG AGGAAGGATG GCTAGAAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028445--CD2AP
IPR001452--SH3_domain

PROSITE

PS50002--SH3

Pfam

PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0031941--C:filamentous actin
GO:0005886--C:plasma membrane
GO:0001726--C:ruffle
GO:0032911--P:negative regulation of transforming growth factor beta1 production
GO:1900182--P:positive regulation of protein localization to nucleus
GO:2000249--P:regulation of actin cytoskeleton reorganization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003573	Anas platyrhynchos	63.47	4.00e-156	544.00
IUUC-Aca-005118	Anolis carolinensis	62.70	5.00e-162	564.00
IUUC-Ame-010657	Astyanax mexicanus	51.13	1.00e-88	320.00
IUUC-Bta-012577	Bos taurus	86.16	0.00e+00	872.00
IUUC-Cja-020010	Callithrix jacchus	88.14	0.00e+00	931.00
IUUC-Cfa-020040	Canis familiaris	93.44	0.00e+00	978.00
IUUC-Cpo-021906	Cavia porcellus	80.44	0.00e+00	790.00
IUUC-Csa-024008	Chlorocebus sabaeus	88.77	0.00e+00	904.00
IUUC-Cho-024359	Choloepus hoffmanni	73.21	1.00e-61	230.00
IUUC-Csv-026228	Ciona savignyi	40.49	3.00e-24	103.00
IUUC-Dre-027661	Danio rerio	55.94	9.00e-93	334.00
IUUC-Dno-029568	Dasypus novemcinctus	85.23	0.00e+00	854.00
IUUC-Dor-030286	Dipodomys ordii	73.75	0.00e+00	696.00
IUUC-Ete-032576	Echinops telfairi	83.74	5.00e-110	391.00
IUUC-Eca-033438	Equus caballus	90.80	0.00e+00	976.00
IUUC-Eeu-034588	Erinaceus europaeus	72.10	2.00e-146	511.00
IUUC-Fca-036597	Felis catus	93.29	0.00e+00	1015.00
IUUC-Fal-037305	Ficedula albicollis	62.96	9.00e-159	553.00
IUUC-Gmo-039516	Gadus morhua	44.87	7.00e-64	238.00
IUUC-Gga-040979	Gallus gallus	64.63	2.00e-171	595.00
IUUC-Gac-041945	Gasterosteus aculeatus	49.87	2.00e-75	276.00
IUUC-Ggo-044488	Gorilla gorilla	89.08	0.00e+00	931.00
IUUC-Hsa-045909	Homo sapiens	88.92	0.00e+00	930.00
IUUC-Itr-049058	Ictidomys tridecemlineatus	88.69	2.00e-121	428.00
IUUC-Lch-049481	Latimeria chalumnae	56.17	5.00e-152	531.00
IUUC-Loc-052715	Lepisosteus oculatus	52.19	3.00e-140	492.00
IUUC-Laf-053444	Loxodonta africana	85.69	0.00e+00	902.00
IUUC-Mcc-054844	Macaca mulatta	88.92	0.00e+00	905.00
IUUC-Meu-056491	Macropus eugenii	64.23	6.00e-173	600.00
IUUC-Mga-060154	Meleagris gallopavo	64.82	1.00e-170	592.00
IUUC-Mmr-061099	Microcebus murinus	88.61	0.00e+00	901.00
IUUC-Mdo-062769	Monodelphis domestica	71.05	0.00e+00	753.00
IUUC-Mmu-063136	Mus musculus	83.78	0.00e+00	788.00
IUUC-Mpu-066509	Mustela putorius furo	94.95	0.00e+00	944.00
IUUC-Mlu-067174	Myotis lucifugus	86.90	0.00e+00	898.00
IUUC-Nle-070147	Nomascus leucogenys	89.39	0.00e+00	941.00
IUUC-Opr-070752	Ochotona princeps	82.19	4.00e-165	574.00
IUUC-Ont-071810	Oreochromis niloticus	53.94	7.00e-99	355.00
IUUC-Oan-072731	Ornithorhynchus anatinus	71.68	3.00e-161	561.00
IUUC-Ocu-074331	Oryctolagus cuniculus	88.94	0.00e+00	893.00
IUUC-Ola-086404	Oryzias latipes	44.62	5.00e-88	318.00
IUUC-Oga-088200	Otolemur garnettii	89.55	0.00e+00	988.00
IUUC-Oar-090423	Ovis aries	85.38	0.00e+00	854.00
IUUC-Ptr-091230	Pan troglodytes	89.24	0.00e+00	934.00
IUUC-Pan-091823	Papio anubis	89.24	0.00e+00	903.00
IUUC-Psi-093127	Pelodiscus sinensis	63.47	4.00e-162	564.00
IUUC-Pfo-096539	Poecilia formosa	49.57	3.00e-87	316.00
IUUC-Pab-097666	Pongo abelii	89.39	0.00e+00	926.00
IUUC-Pca-100812	Procavia capensis	80.33	2.00e-127	449.00
IUUC-Pva-102260	Pteropus vampyrus	82.42	0.00e+00	764.00
IUUC-Rno-106038	Rattus norvegicus	83.31	0.00e+00	817.00
IUUC-Sha-106975	Sarcophilus harrisii	71.25	0.00e+00	706.00
IUUC-Sar-113386	Sorex araneus	84.15	1.00e-103	370.00
IUUC-Ssc-115569	Sus scrofa	93.44	3.00e-115	407.00
IUUC-Tgu-117104	Taeniopygia guttata	64.22	2.00e-174	605.00
IUUC-Tru-117649	Takifugu rubripes	52.01	4.00e-96	345.00
IUUC-Tsy-119258	Tarsius syrichta	80.78	0.00e+00	826.00
IUUC-Tni-120755	Tetraodon nigroviridis	45.56	2.00e-126	446.00
IUUC-Tbe-127842	Tupaia belangeri	70.42	0.00e+00	648.00
IUUC-Ttr-129205	Tursiops truncatus	89.42	0.00e+00	827.00
IUUC-Vpa-130434	Vicugna pacos	84.81	0.00e+00	768.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence