iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000004067.2	ENSCJAT00000007849.2	ENSCJAP00000007428.2
ENSCJAG00000004067.2	ENSCJAT00000007843.2	ENSCJAP00000007422.2
ENSCJAG00000004067.2	ENSCJAT00000059920.1	ENSCJAP00000045741.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.00e-69	235.3	420	798

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw......kskkk.............avspr 71
           Gl N gN CY+N++LQ+L+++p++ +l+++  +   +  +++ +++++++s+ +l++e++      k ++              a++p+
   Q: 420  GLINKGNWCYINATLQALVACPPMYHLMKS-IPLYSK-VQRPCTSTPMIDSFVRLMNEFTnmpvppKPRQAlgdkmardirpgaAFEPT 506
           9*****************************.333333.334799***************7666654333336677778888888***** PP
   S: 72   ellkalkkeaeefs.gyeqqDaqEflaflldqleeelkk.................eknkpkeeeeeedkselsdeaeekkkkknk... 139
            +++ l   ++++s + +q+Da+E+l f+l++l+ee+ +                  kn+++ eee+e++ e s++++e+   +nk   
   Q: 507  YIYRLLTVNKSSLSeKGRQEDAEEYLGFILNGLHEEMVNlkkllspnndklkisngPKNHSVREEEQEEQGEGSEDEWEQVGPRNKtsv 595
           ******99999866599********************6667799999999999999888888888888888888887777777776677 PP
   S: 140  ........slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekk 220
                   ++i+ +F+g+++ +++ ++  ++s + +pf++l+l++++++ +   ++qd+Les +++e+++g    y++k k+++e +++
   Q: 596  trqadfvqTPITGIFGGHIR-SVVYQQSSKESATLQPFFTLQLDIQSDKIR---TVQDALESLVARESVQG----YTTKTKQEVEISRR 676
           77777888***********9.688999999*******************99...****************8....99999********* PP
   S: 221  lklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke...kkkYeLiavvvHsG.slssGHYvayvknekgk 305
           ++l+klP+vL+lhLkRf ++++++++ k+ k++e+p  L++s+ + sp  k+k+   +++Y+L+avv+H+G s+ +GHY+++v +   +
   Q: 677  VTLEKLPPVLVLHLKRFVYEKTGGCQ-KLIKNIEYPVDLEISKELLSPGVKNKNfkcHRTYRLFAVVYHHGnSATGGHYTTDVFQIGLN 764
           *******************9998886.****************999988777777879***************************8777 PP
   S: 306  .WllfdDskVtevkeeevleetg.staYvlfYkr 337
            Wl++dD++V+++++ +v++ t+ +taY+l+Y+r
   Q: 765  gWLRIDDQTVKVTNQYQVVRPTAeRTAYLLYYRR 798
           7******************98889********98 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MPWLPSPGIG RYIFGDFSPD EFNQFFVTPR SSVELPPYSG TALCGTQAVD QLPDGQEYQR 60
IEFGVNEVIE PSDTLPRTPS YSISSTLNPQ APEFILGCTT SKMTPGGVTK EASYGSADCQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCCCGCGC CCCGCGGCGG GCGGCCAGTG CGCAGGCGCG GCGGCCGATG TGAGTGTGTA 60
TGTGCGGGCG AGAAGATGGC GGCGGCGGGG GAAGCAGCGT GAGCAGCCGG AGGAGCGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009818--Ataxin-2_C
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF07145--PAM2
PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005654--C:nucleoplasm
GO:0043234--C:protein complex
GO:0004197--F:cysteine-type endopeptidase activity
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0071347--P:cellular response to interleukin-1
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016579--P:protein deubiquitination
GO:0010506--P:regulation of autophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000082	Aegilops tauschii	30.38	1.00e-43	171.00
IUUC-Aml-001584	Ailuropoda melanoleuca	87.37	0.00e+00	1312.00
IUUC-Atr-002927	Amborella trichopoda	34.96	6.00e-57	215.00
IUUC-Apl-003988	Anas platyrhynchos	77.67	0.00e+00	1137.00
IUUC-Aca-004461	Anolis carolinensis	87.72	4.00e-162	563.00
IUUC-Aly-006038	Arabidopsis lyrata	35.31	9.00e-53	201.00
IUUC-Ath-007328	Arabidopsis thaliana	35.05	1.00e-51	197.00
IUUC-Ago-007717	Ashbya gossypii	29.89	4.00e-43	169.00
IUUC-Acl-008188	Aspergillus clavatus	33.41	3.00e-61	230.00
IUUC-Afl-008456	Aspergillus flavus	36.18	2.00e-46	179.00
IUUC-Afu-009067	Aspergillus fumigatus	36.45	3.00e-64	240.00
IUUC-Ani-009483	Aspergillus nidulans	33.26	6.00e-62	232.00
IUUC-Ang-009639	Aspergillus niger	34.61	3.00e-59	223.00
IUUC-Aor-010040	Aspergillus oryzae	34.30	3.00e-58	220.00
IUUC-Ate-010310	Aspergillus terreus	32.23	1.00e-60	228.00
IUUC-Ame-011012	Astyanax mexicanus	71.43	1.00e-162	567.00
IUUC-Bgr-012311	Blumeria graminis	35.05	3.00e-44	173.00
IUUC-Bta-013299	Bos taurus	86.40	0.00e+00	1251.00
IUUC-Bci-013783	Botrytis cinerea	36.69	3.00e-58	220.00
IUUC-Bdi-015039	Brachypodium distachyon	31.40	5.00e-49	189.00
IUUC-Bol-015806	Brassica oleracea	35.46	5.00e-60	225.00
IUUC-Bra-017076	Brassica rapa	35.71	3.00e-60	226.00
IUUC-Cfa-020194	Canis familiaris	87.75	0.00e+00	1322.00
IUUC-Cpo-022272	Cavia porcellus	74.78	0.00e+00	1048.00
IUUC-Cre-022713	Chlamydomonas reinhardtii	34.80	1.00e-34	141.00
IUUC-Csa-023310	Chlorocebus sabaeus	95.33	0.00e+00	1468.00
IUUC-Cho-024966	Choloepus hoffmanni	77.46	0.00e+00	940.00
IUUC-Cin-025616	Ciona intestinalis	48.09	2.00e-105	376.00
IUUC-Csv-026043	Ciona savignyi	46.81	2.00e-98	352.00
IUUC-Cgl-026421	Colletotrichum gloeosporioides	33.97	7.00e-46	179.00
IUUC-Cne-026962	Cryptococcus neoformans	35.52	4.00e-51	197.00
IUUC-Cme-027113	Cyanidioschyzon merolae	29.98	1.00e-35	144.00
IUUC-Dre-028072	Danio rerio	77.63	0.00e+00	711.00
IUUC-Dno-029489	Dasypus novemcinctus	87.17	0.00e+00	1342.00
IUUC-Dor-031068	Dipodomys ordii	73.12	2.00e-137	483.00
IUUC-Dse-031553	Dothistroma septosporum	36.55	2.00e-56	214.00
IUUC-Dme-031759	Drosophila melanogaster	40.72	1.00e-82	301.00
IUUC-Ete-032549	Echinops telfairi	76.53	0.00e+00	871.00
IUUC-Eca-033380	Equus caballus	85.50	0.00e+00	1318.00
IUUC-Eeu-034818	Erinaceus europaeus	82.85	0.00e+00	1223.00
IUUC-Fca-035535	Felis catus	85.68	0.00e+00	1183.00
IUUC-Fal-036627	Ficedula albicollis	76.20	0.00e+00	1099.00
IUUC-Fox-037904	Fusarium oxysporum	36.03	8.00e-53	202.00
IUUC-Fso-038170	Fusarium solani	34.10	2.00e-52	201.00
IUUC-Gmo-039499	Gadus morhua	70.02	0.00e+00	665.00
IUUC-Ggr-040042	Gaeumannomyces graminis	35.01	4.00e-61	229.00
IUUC-Gga-040571	Gallus gallus	77.99	0.00e+00	1130.00
IUUC-Gac-041345	Gasterosteus aculeatus	76.08	0.00e+00	660.00
IUUC-Gma-044407	Glycine max	34.27	1.00e-57	217.00
IUUC-Ggo-044652	Gorilla gorilla	95.58	0.00e+00	1498.00
IUUC-Hsa-045864	Homo sapiens	95.83	0.00e+00	1503.00
IUUC-Hvu-047071	Hordeum vulgare	32.73	2.00e-51	196.00
IUUC-Itr-048216	Ictidomys tridecemlineatus	88.68	0.00e+00	999.00
IUUC-Kpa-049132	Komagataella pastoris	30.94	1.00e-44	174.00
IUUC-Lch-050040	Latimeria chalumnae	68.64	0.00e+00	915.00
IUUC-Loc-052449	Lepisosteus oculatus	74.07	0.00e+00	709.00
IUUC-Lma-053248	Leptosphaeria maculans	35.66	2.00e-56	214.00
IUUC-Laf-054121	Loxodonta africana	87.01	0.00e+00	1304.00
IUUC-Mcc-055514	Macaca mulatta	95.89	0.00e+00	1500.00
IUUC-Meu-056873	Macropus eugenii	71.74	0.00e+00	811.00
IUUC-Mor-057243	Magnaporthe oryzae	33.67	3.00e-58	220.00
IUUC-Mpo-057439	Magnaporthe poae	35.28	7.00e-61	229.00
IUUC-Mtr-058457	Medicago truncatula	33.59	2.00e-55	210.00
IUUC-Mla-058929	Melampsora laricipopulina	31.38	1.00e-56	214.00
IUUC-Mga-060157	Meleagris gallopavo	75.83	0.00e+00	1129.00
IUUC-Mvi-060442	Microbotryum violaceum	33.08	1.00e-54	209.00
IUUC-Mmr-061062	Microcebus murinus	91.27	0.00e+00	1443.00
IUUC-Mdo-062798	Monodelphis domestica	79.57	0.00e+00	1191.00
IUUC-Mmu-064050	Mus musculus	81.97	0.00e+00	1254.00
IUUC-Mac-065619	Musa acuminata	34.27	2.00e-53	202.00
IUUC-Mpu-066554	Mustela putorius furo	86.38	0.00e+00	1276.00
IUUC-Mlu-068003	Myotis lucifugus	85.98	0.00e+00	1298.00
IUUC-Nfi-068612	Neosartorya fischeri	35.25	7.00e-63	235.00
IUUC-Ncr-068878	Neurospora crassa	34.37	1.00e-51	198.00
IUUC-Nle-069661	Nomascus leucogenys	95.83	0.00e+00	1476.00
IUUC-Opr-070944	Ochotona princeps	76.03	5.00e-169	587.00
IUUC-Ont-071266	Oreochromis niloticus	57.61	0.00e+00	798.00
IUUC-Oan-073442	Ornithorhynchus anatinus	78.27	0.00e+00	1115.00
IUUC-Ocu-073788	Oryctolagus cuniculus	80.29	0.00e+00	1123.00
IUUC-Oba-075085	Oryza barthii	33.09	1.00e-36	146.00
IUUC-Obr-076663	Oryza brachyantha	32.91	1.00e-45	177.00
IUUC-Ogl-076937	Oryza glaberrima	29.80	1.00e-47	184.00
IUUC-Ogu-078909	Oryza glumaepatula	29.97	1.00e-45	178.00
IUUC-Oin-079617	Oryza indica	31.40	1.00e-47	184.00
IUUC-Olo-081043	Oryza longistaminata	25.76	5.00e-24	105.00
IUUC-Ome-081646	Oryza meridionalis	24.48	1.00e-22	101.00
IUUC-Oni-082914	Oryza nivara	29.97	7.00e-46	178.00
IUUC-Oru-084878	Oryza rufipogon	29.97	6.00e-46	178.00
IUUC-Osa-085822	Oryza sativa	30.67	1.00e-49	190.00
IUUC-Ola-086931	Oryzias latipes	56.97	0.00e+00	773.00
IUUC-Oga-088443	Otolemur garnettii	90.91	0.00e+00	1414.00
IUUC-Oar-089325	Ovis aries	83.21	0.00e+00	1159.00
IUUC-Ptr-091584	Pan troglodytes	92.68	0.00e+00	1407.00
IUUC-Pan-092551	Papio anubis	93.43	0.00e+00	1431.00
IUUC-Psi-093366	Pelodiscus sinensis	74.57	0.00e+00	692.00
IUUC-Pno-095136	Phaeosphaeria nodorum	34.88	1.00e-51	198.00
IUUC-Ppa-095574	Physcomitrella patens	34.47	2.00e-58	220.00
IUUC-Pfo-097462	Poecilia formosa	70.02	0.00e+00	691.00
IUUC-Pab-098547	Pongo abelii	95.96	0.00e+00	1475.00
IUUC-Pop-099529	Populus trichocarpa	36.83	1.00e-60	227.00
IUUC-Pca-101066	Procavia capensis	77.90	0.00e+00	1147.00
IUUC-Ppe-102110	Prunus persica	35.88	4.00e-58	218.00
IUUC-Pva-103015	Pteropus vampyrus	81.46	0.00e+00	1216.00
IUUC-Ptt-103998	Puccinia triticina	32.29	3.00e-53	203.00
IUUC-Pte-104417	Pyrenophora teres	33.50	1.00e-54	208.00
IUUC-Pyt-104820	Pyrenophora triticirepentis	34.95	8.00e-55	208.00
IUUC-Rno-105533	Rattus norvegicus	82.62	0.00e+00	1250.00
IUUC-Sce-106160	Saccharomyces cerevisiae	28.05	2.00e-37	151.00
IUUC-Sha-106590	Sarcophilus harrisii	80.45	0.00e+00	1191.00
IUUC-Sja-107669	Schizosaccharomyces japonicus	36.59	2.00e-59	223.00
IUUC-Spo-108353	Schizosaccharomyces pombe	37.71	9.00e-66	244.00
IUUC-Ssl-108599	Sclerotinia sclerotiorum	37.18	2.00e-58	221.00
IUUC-Smo-108842	Selaginella moellendorffii	35.48	5.00e-36	144.00
IUUC-Sit-110781	Setaria italica	32.48	8.00e-54	205.00
IUUC-Sly-111797	Solanum lycopersicum	33.76	1.00e-54	207.00
IUUC-Stu-112188	Solanum tuberosum	34.18	1.00e-54	207.00
IUUC-Sbi-114862	Sorghum bicolor	33.14	5.00e-44	172.00
IUUC-Sre-115162	Sporisorium reilianum	35.67	5.00e-67	249.00
IUUC-Ssc-115505	Sus scrofa	94.48	2.00e-163	568.00
IUUC-Tgu-116535	Taeniopygia guttata	75.79	0.00e+00	1098.00
IUUC-Tru-117542	Takifugu rubripes	76.99	0.00e+00	706.00
IUUC-Tni-120200	Tetraodon nigroviridis	57.59	0.00e+00	793.00
IUUC-Tca-121548	Theobroma cacao	34.60	2.00e-43	170.00
IUUC-Tre-122124	Trichoderma reesei	31.98	3.00e-61	229.00
IUUC-Tvi-122457	Trichoderma virens	34.97	8.00e-54	205.00
IUUC-Tae-125646	Triticum aestivum	33.51	2.00e-53	203.00
IUUC-Tme-127180	Tuber melanosporum	39.35	6.00e-69	255.00
IUUC-Tbe-127530	Tupaia belangeri	74.45	0.00e+00	1036.00
IUUC-Ttr-128549	Tursiops truncatus	78.70	0.00e+00	1167.00
IUUC-Uma-129381	Ustilago maydis	34.05	2.00e-65	243.00
IUUC-Vda-129889	Verticillium dahliae	32.80	3.00e-53	203.00
IUUC-Vpa-130100	Vicugna pacos	79.97	0.00e+00	1185.00
IUUC-Vvi-131366	Vitis vinifera	35.62	8.00e-62	231.00
IUUC-Xtr-132048	Xenopus tropicalis	62.78	0.00e+00	898.00
IUUC-Xma-133593	Xiphophorus maculatus	70.40	0.00e+00	688.00
IUUC-Yli-134338	Yarrowia lipolytica	32.17	8.00e-33	135.00
IUUC-Zma-135586	Zea mays	32.25	1.00e-47	184.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence