iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	3.20e-28	97.3	345	371

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 2    eaqWaCsaCTflNePeavkCemCsrpR 28
           + qWaC++CTf+Ne++av C++C+rpR
   Q: 345  RDQWACQSCTFENEAAAVLCAICERPR 371
           579***********************9 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MPGDEERAFL AAREELASAL RWDSAQVFPL EQLTPLLATS LPLSSRYRQL DAGRLVRCNA 60
HGEPRNYLNT LSTALNILEK YGRNLLSPQR PRYWRSVKFN NPVFRSTVDA VQGGRDVLRL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGAACCCGCC TTTTCCTCCA AAGTGGTCCA CAGTCCCGCC CTCTCTGCCA GGACTTCCTG 60
TTCCCGGTAA CCCTGGCCGT GGCTGGGTTT GTAGCGGGGC GGTGGCTTGA GTGACCCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR002867--IBR_dom
IPR018997--PUB_domain
IPR026254--RNF31
IPR032065--RNF31-UBA
IPR015940--UBA
IPR001876--Znf_RanBP2
IPR017907--Znf_RING_CS

PROSITE

PS50030--UBA
PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS00518--ZF_RING_1

Pfam

PF16678--HOIP-UBA
PF01485--IBR
PF09409--PUB

SMART

SM00647--IBR
SM00547--ZnF_RBZ

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:0071797--C:LUBAC complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0023035--P:CD40 signaling pathway
GO:0060546--P:negative regulation of necroptotic process
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling

KEGG

rno:364386

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002017	Ailuropoda melanoleuca	84.45	0.00e+00	1642.00
IUUC-Aca-004719	Anolis carolinensis	55.01	0.00e+00	866.00
IUUC-Ame-011924	Astyanax mexicanus	37.50	7.00e-112	398.00
IUUC-Bta-012795	Bos taurus	81.42	0.00e+00	1579.00
IUUC-Cja-019168	Callithrix jacchus	84.06	0.00e+00	1696.00
IUUC-Cfa-020767	Canis familiaris	84.20	0.00e+00	1669.00
IUUC-Cpo-022291	Cavia porcellus	83.47	0.00e+00	1701.00
IUUC-Csa-024246	Chlorocebus sabaeus	83.54	0.00e+00	1451.00
IUUC-Cho-024866	Choloepus hoffmanni	56.79	0.00e+00	840.00
IUUC-Cin-025568	Ciona intestinalis	33.77	1.00e-95	344.00
IUUC-Dre-027426	Danio rerio	43.39	0.00e+00	764.00
IUUC-Dno-029925	Dasypus novemcinctus	82.00	0.00e+00	1598.00
IUUC-Dor-030389	Dipodomys ordii	81.84	0.00e+00	1318.00
IUUC-Dme-031816	Drosophila melanogaster	43.70	1.00e-87	319.00
IUUC-Ete-032383	Echinops telfairi	91.99	0.00e+00	706.00
IUUC-Eca-033807	Equus caballus	84.37	0.00e+00	1698.00
IUUC-Eeu-034745	Erinaceus europaeus	70.45	0.00e+00	754.00
IUUC-Fca-036464	Felis catus	85.29	0.00e+00	1688.00
IUUC-Gmo-039121	Gadus morhua	42.99	2.00e-178	620.00
IUUC-Gac-041766	Gasterosteus aculeatus	46.53	0.00e+00	838.00
IUUC-Ggo-045259	Gorilla gorilla	84.70	0.00e+00	1697.00
IUUC-Hsa-046269	Homo sapiens	84.70	0.00e+00	1696.00
IUUC-Itr-048764	Ictidomys tridecemlineatus	85.97	0.00e+00	1840.00
IUUC-Lch-049622	Latimeria chalumnae	51.46	0.00e+00	1068.00
IUUC-Laf-054027	Loxodonta africana	82.08	0.00e+00	1605.00
IUUC-Mcc-054906	Macaca mulatta	84.70	0.00e+00	1739.00
IUUC-Meu-056354	Macropus eugenii	66.76	0.00e+00	1298.00
IUUC-Mmr-060835	Microcebus murinus	82.95	0.00e+00	1639.00
IUUC-Mdo-061883	Monodelphis domestica	74.42	0.00e+00	1496.00
IUUC-Mmu-064014	Mus musculus	94.37	0.00e+00	1903.00
IUUC-Mlu-067075	Myotis lucifugus	82.94	0.00e+00	1629.00
IUUC-Nle-069954	Nomascus leucogenys	84.61	0.00e+00	1706.00
IUUC-Opr-070399	Ochotona princeps	78.92	0.00e+00	1600.00
IUUC-Ont-071593	Oreochromis niloticus	46.97	0.00e+00	858.00
IUUC-Oan-073591	Ornithorhynchus anatinus	92.31	3.00e-47	179.00
IUUC-Ocu-073785	Oryctolagus cuniculus	65.14	0.00e+00	1196.00
IUUC-Ogl-077291	Oryza glaberrima	25.77	1.00e-03	37.40
IUUC-Oin-079800	Oryza indica	26.02	1.00e-03	37.40
IUUC-Oni-082829	Oryza nivara	26.02	1.00e-03	37.40
IUUC-Ola-086357	Oryzias latipes	45.75	0.00e+00	820.00
IUUC-Oga-088724	Otolemur garnettii	85.81	0.00e+00	1667.00
IUUC-Oar-089318	Ovis aries	82.00	0.00e+00	1690.00
IUUC-Ptr-091249	Pan troglodytes	84.70	0.00e+00	1717.00
IUUC-Pan-092080	Papio anubis	85.18	0.00e+00	1760.00
IUUC-Pma-094655	Petromyzon marinus	50.21	1.00e-67	249.00
IUUC-Pfo-096097	Poecilia formosa	45.63	0.00e+00	831.00
IUUC-Pab-098380	Pongo abelii	82.29	0.00e+00	1645.00
IUUC-Pca-101024	Procavia capensis	77.83	0.00e+00	1571.00
IUUC-Pva-102289	Pteropus vampyrus	83.12	0.00e+00	1611.00
IUUC-Sha-107428	Sarcophilus harrisii	73.70	0.00e+00	1427.00
IUUC-Ssl-108588	Sclerotinia sclerotiorum	29.58	9.00e-03	34.70
IUUC-Sar-113745	Sorex araneus	79.37	0.00e+00	1606.00
IUUC-Ssc-116246	Sus scrofa	82.95	0.00e+00	1621.00
IUUC-Tru-118704	Takifugu rubripes	45.87	0.00e+00	816.00
IUUC-Tsy-119077	Tarsius syrichta	83.08	0.00e+00	1379.00
IUUC-Tni-120343	Tetraodon nigroviridis	44.76	0.00e+00	809.00
IUUC-Tbe-127822	Tupaia belangeri	85.97	0.00e+00	776.00
IUUC-Ttr-129179	Tursiops truncatus	80.46	0.00e+00	1576.00
IUUC-Xtr-132864	Xenopus tropicalis	50.24	0.00e+00	946.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence