iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118722

Ensembl Protein ID

ENSTRUP00000046321.1

UniProt Accession

H2VAS9; H2VAS9_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000018093.1	ENSTRUT00000046478.1	ENSTRUP00000046321.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-16	60.9	51	84
UBD/Beta-Prp	1.90e-47	163.2	8	230

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sd.tllvsGsdDgtikvWD 29
           gHt++++cl      ++ + l +Gs D ti++++
   Q: 51   GHTNKINCLLVsstpNTpPCLFTGSSDQTIRCYS 84
           8*******955999655789************98 PP

UBD/Beta-Prp

   S: 47   slsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvls..lsfspsg.dklvsGshdrtirvwdletgqcleet 132
            +++h+++v  ++  +d   l t+s D+t++ ++ls+++c  +++gh++++ +  +s+ p++   l +Gs+d+tir++ ++  + ++ +
   Q: 8    PFENHQGPVHGLQVYQD--RLYTCSGDNTARAYSLSNRDCQAVFTGHTNKINCllVSSTPNTpPCLFTGSSDQTIRCYSIKVHSYSQ-V 93
           5789*************..7*******************************994456666888*****************9999999.7 PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng..kelvsgsldgtvklwdlqtgecvrtln 219
            s  d+v   +++ +  n+l +G + + v  +dlkt k ++ ++    + v +l   ++g  + l+ gs+d+t+ + d ++g  +r l 
   Q: 94   ISLSDRV---LCLLSAWNVLYAGLASGSVASFDLKTLKPMDVFECHGPRGVSCLGAAQEGarRVLLVGSYDSTISVRDAKSGLLLRMLD 179
           7777644...44444447*************************996788899999999988899************************* PP
   S: 220  ghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvav 272
           gh ++v+++r+   ++++ s+ssD+s+r +++ +g+l++++++h + v+s+  
   Q: 180  GHAKTVLCLRVV--NDLVFSASSDRSVRTHNIHTGELVRVYKGHGHAVTSIVI 230
           ************..99*****************************99999876 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

EEEPSLGPFE NHQGPVHGLQ VYQDRLYTCS GDNTARAYSL SNRDCQAVFT GHTNKINCLL 60
VSSTPNTPPC LFTGSSDQTI RCYSIKVHSY SQVISLSDRV LCLLSAWNVL YAGLASGSVA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGAGGAAC CATCTCTGGG ACCATTTGAG AACCACCAGG GCCCCGTCCA CGGCCTCCAG 60
GTGTACCAGG ACCGGTTGTA TACGTGTTCG GGGGACAACA CGGCGCGCGC CTACAGCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR013087--Znf_C2H2_type

PROSITE

PS50294--WD_REPEATS_REGION
PS00028--ZINC_FINGER_C2H2_1

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0016020--C:membrane
GO:0046872--F:metal ion binding
GO:0017124--F:SH3 domain binding
GO:0008286--P:insulin receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Gmo-038857	Gadus morhua	68.98	8.00e-154	537.00
IUUC-Gac-042155	Gasterosteus aculeatus	72.88	1.00e-166	580.00
IUUC-Ont-072462	Oreochromis niloticus	76.16	5.00e-173	601.00
IUUC-Ola-087573	Oryzias latipes	77.26	7.00e-176	610.00
IUUC-Pfo-096630	Poecilia formosa	73.70	5.00e-168	585.00
IUUC-Tni-119662	Tetraodon nigroviridis	80.00	1.00e-176	613.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence