iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-055192

Ensembl Protein ID

ENSMMUP00000003268.3

UniProt Accession

F6PLB8; F6PLB8_MACMU

Genbank Protein ID

ENSMMUP00000003268

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

JSUE03029455

Gene Name

ING3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000002434.3	ENSMMUT00000003458.3	ENSMMUP00000003268.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.90e-09	38.1	351	398

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  +v C++  C  ewfH++C++l+   e p+ + w+Cp+C++
   Q: 351  RYC-ICNQVSYGE--MVGCDNqdCPiEWFHYGCVGLT---EAPKGK-WYCPQCTA 398
           69*.*******99..*****999*99***********...999997.******86 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MLYLEDYLEM IEQLPMDLRD RFTEMREMDL QVQNAMDQLE QRVSEFFMNA KKNKPEWREE 60
QMASIKKDYY KALEDADEKV QLANQIYDLV DRHLRKLDQE LAKFKMELEA DNAGITEILE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGTACC TAGAAGACTA TCTGGAAAGT GAGTGCGCGG CGCTGGCGGC GGCCGCCGGT 60
GGGACCTGCG GGAGGGCAAG AGCGCGAGTG GACGGGCAGC GAGATGGCGG GAGGGAGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0032777--C:Piccolo NuA4 histone acetyltransferase complex
GO:0000812--C:Swr1 complex
GO:0004402--F:histone acetyltransferase activity
GO:0008270--F:zinc ion binding
GO:0043968--P:histone H2A acetylation
GO:0043967--P:histone H4 acetylation
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002275	Ailuropoda melanoleuca	95.69	0.00e+00	648.00
IUUC-Apl-003660	Anas platyrhynchos	85.57	2.00e-148	518.00
IUUC-Aca-005206	Anolis carolinensis	87.32	8.00e-156	543.00
IUUC-Aly-005815	Arabidopsis lyrata	68.12	1.00e-28	120.00
IUUC-Ath-006765	Arabidopsis thaliana	66.67	5.00e-28	117.00
IUUC-Acl-008091	Aspergillus clavatus	62.26	7.00e-19	89.00
IUUC-Ate-010297	Aspergillus terreus	62.26	4.00e-19	89.70
IUUC-Ame-011952	Astyanax mexicanus	80.91	4.00e-152	531.00
IUUC-Bta-012562	Bos taurus	94.74	0.00e+00	647.00
IUUC-Cja-019646	Callithrix jacchus	94.74	0.00e+00	644.00
IUUC-Cfa-020874	Canis familiaris	95.69	0.00e+00	650.00
IUUC-Cpo-022530	Cavia porcellus	94.98	0.00e+00	632.00
IUUC-Csa-024232	Chlorocebus sabaeus	96.65	0.00e+00	654.00
IUUC-Cho-025039	Choloepus hoffmanni	93.30	3.00e-180	624.00
IUUC-Cin-025233	Ciona intestinalis	59.12	8.00e-52	197.00
IUUC-Csv-025900	Ciona savignyi	71.97	3.00e-50	192.00
IUUC-Dre-027397	Danio rerio	76.85	3.00e-143	501.00
IUUC-Dno-029289	Dasypus novemcinctus	95.45	0.00e+00	647.00
IUUC-Dse-031323	Dothistroma septosporum	55.93	4.00e-18	86.70
IUUC-Ete-032510	Echinops telfairi	86.12	4.00e-149	521.00
IUUC-Eca-033770	Equus caballus	95.93	0.00e+00	650.00
IUUC-Fca-035661	Felis catus	94.98	0.00e+00	647.00
IUUC-Fal-037051	Ficedula albicollis	87.79	4.00e-144	504.00
IUUC-Gmo-039123	Gadus morhua	80.98	4.00e-160	557.00
IUUC-Gga-040794	Gallus gallus	89.47	5.00e-164	570.00
IUUC-Gac-042167	Gasterosteus aculeatus	81.02	4.00e-156	544.00
IUUC-Ggo-044586	Gorilla gorilla	82.46	1.00e-159	555.00
IUUC-Hsa-046035	Homo sapiens	96.65	0.00e+00	655.00
IUUC-Itr-048783	Ictidomys tridecemlineatus	95.93	0.00e+00	650.00
IUUC-Lch-049419	Latimeria chalumnae	80.86	9.00e-164	569.00
IUUC-Loc-052246	Lepisosteus oculatus	83.53	8.00e-161	560.00
IUUC-Lma-053234	Leptosphaeria maculans	53.85	3.00e-17	84.00
IUUC-Laf-053617	Loxodonta africana	94.74	7.00e-180	623.00
IUUC-Meu-056848	Macropus eugenii	77.75	4.00e-133	468.00
IUUC-Mga-059899	Meleagris gallopavo	88.31	7.00e-143	499.00
IUUC-Mmr-061435	Microcebus murinus	98.78	0.00e+00	659.00
IUUC-Mmu-064032	Mus musculus	91.92	0.00e+00	636.00
IUUC-Mpu-066530	Mustela putorius furo	95.45	0.00e+00	651.00
IUUC-Mlu-067790	Myotis lucifugus	95.69	0.00e+00	648.00
IUUC-Nle-070171	Nomascus leucogenys	96.65	0.00e+00	655.00
IUUC-Opr-070865	Ochotona princeps	69.95	5.00e-66	244.00
IUUC-Ont-072045	Oreochromis niloticus	79.57	6.00e-153	533.00
IUUC-Oan-073641	Ornithorhynchus anatinus	86.68	2.00e-148	518.00
IUUC-Ocu-074613	Oryctolagus cuniculus	95.69	0.00e+00	650.00
IUUC-Oga-088624	Otolemur garnettii	95.23	0.00e+00	634.00
IUUC-Oar-089442	Ovis aries	94.26	0.00e+00	640.00
IUUC-Ptr-091208	Pan troglodytes	96.65	0.00e+00	655.00
IUUC-Pan-092715	Papio anubis	96.89	0.00e+00	654.00
IUUC-Psi-093455	Pelodiscus sinensis	88.52	1.00e-162	566.00
IUUC-Pma-094144	Petromyzon marinus	79.78	2.00e-44	171.00
IUUC-Pfo-096573	Poecilia formosa	81.15	7.00e-153	533.00
IUUC-Pab-097549	Pongo abelii	96.65	0.00e+00	655.00
IUUC-Pca-100198	Procavia capensis	90.67	9.00e-180	622.00
IUUC-Pva-102440	Pteropus vampyrus	94.50	0.00e+00	641.00
IUUC-Pte-104284	Pyrenophora teres	54.24	3.00e-17	84.30
IUUC-Pyt-104787	Pyrenophora triticirepentis	55.93	2.00e-17	84.70
IUUC-Rno-105532	Rattus norvegicus	92.64	7.00e-180	623.00
IUUC-Sha-107475	Sarcophilus harrisii	90.67	4.00e-171	593.00
IUUC-Sar-113193	Sorex araneus	93.78	0.00e+00	628.00
IUUC-Ssc-115795	Sus scrofa	95.45	0.00e+00	645.00
IUUC-Tgu-117305	Taeniopygia guttata	87.79	4.00e-146	510.00
IUUC-Tru-117691	Takifugu rubripes	79.52	5.00e-148	517.00
IUUC-Tsy-119035	Tarsius syrichta	80.73	4.00e-84	305.00
IUUC-Tni-120738	Tetraodon nigroviridis	75.66	9.00e-152	529.00
IUUC-Ttr-128512	Tursiops truncatus	90.19	0.00e+00	644.00
IUUC-Xma-133522	Xiphophorus maculatus	81.38	2.00e-153	535.00
IUUC-Zma-135298	Zea mays	67.80	2.00e-24	106.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence