iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092178

Ensembl Protein ID

ENSPANP00000019884.1

UniProt Accession

A0A096P3F9; A0A096P3F9_PAPAN

Genbank Protein ID

ENSPANP00000019884

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01196370

Gene Name

OPTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000023366.1	ENSPANT00000021604.1	ENSPANP00000019884.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	3.20e-26	91.1	457	516

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndslkas 60
           +ee+let++vL++Q+e+Y++DF+aERa+RE+++eeke+L+ q+++l+k++++++d++++s
   Q: 457  QEEDLETMTVLRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAVLLKENDAFEDGGRQS 516
           79********************************************************98 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MSHQPLSCLT ENGGSPSEST GNGPPQLAHP NLDTFTPEEL LQQMKELLTE NHQLKEAMKL 60
NNQAMKGRFE ELSAWTEKQK EERQFFETQS KEAKERLMAL SHENERLKEE LGKLKGKSER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTCCCTGGT CAACGTCCCA TCCTGGTCGG CAGCTCTCTC CAGGCGGCAC GATGCCAAGG 60
AAGCAGTGAC CCTGAGCGAA GCCAAGCCGG GCTGGCAGGT GAGCCAGGGC AGGAGGCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR021063--NEMO_N
IPR032939--Optineurin
IPR034735--ZF_CCHC_NOA

PROSITE

PS51801--ZF_CCHC_NOA

Pfam

PF16516--CC2-LZ
PF11577--NEMO

Gene Ontology

GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0048471--C:perinuclear region of cytoplasm
GO:0005802--C:trans-Golgi network
GO:0050829--P:defense response to Gram-negative bacterium
GO:0090161--P:Golgi ribbon formation
GO:0043001--P:Golgi to plasma membrane protein transport
GO:0016236--P:macroautophagy
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0001920--P:negative regulation of receptor recycling
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:1904417--P:positive regulation of xenophagy
GO:0000042--P:protein targeting to Golgi

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002037	Ailuropoda melanoleuca	81.53	0.00e+00	795.00
IUUC-Apl-003812	Anas platyrhynchos	56.54	3.00e-153	535.00
IUUC-Aca-004625	Anolis carolinensis	56.36	3.00e-151	528.00
IUUC-Aly-005781	Arabidopsis lyrata	55.00	2.10e-02	33.50
IUUC-Ame-011116	Astyanax mexicanus	38.14	2.00e-74	273.00
IUUC-Bta-013240	Bos taurus	83.33	0.00e+00	904.00
IUUC-Cja-019911	Callithrix jacchus	94.14	0.00e+00	981.00
IUUC-Cfa-020330	Canis familiaris	84.91	0.00e+00	847.00
IUUC-Cpo-021753	Cavia porcellus	80.85	0.00e+00	823.00
IUUC-Csa-023662	Chlorocebus sabaeus	97.76	0.00e+00	1009.00
IUUC-Cho-024574	Choloepus hoffmanni	67.92	3.00e-129	454.00
IUUC-Cme-027299	Cyanidioschyzon merolae	35.96	3.00e-03	36.60
IUUC-Dre-027720	Danio rerio	40.84	7.00e-92	331.00
IUUC-Dno-029079	Dasypus novemcinctus	79.25	0.00e+00	768.00
IUUC-Dor-030890	Dipodomys ordii	80.76	0.00e+00	834.00
IUUC-Dme-032072	Drosophila melanogaster	26.27	6.00e-03	35.00
IUUC-Ete-032568	Echinops telfairi	82.54	0.00e+00	755.00
IUUC-Eca-033528	Equus caballus	84.01	0.00e+00	849.00
IUUC-Eeu-035219	Erinaceus europaeus	74.74	0.00e+00	817.00
IUUC-Fca-035852	Felis catus	83.87	0.00e+00	848.00
IUUC-Fal-036862	Ficedula albicollis	57.79	7.00e-150	523.00
IUUC-Gmo-038735	Gadus morhua	39.82	2.00e-78	286.00
IUUC-Gga-040939	Gallus gallus	58.20	7.00e-155	540.00
IUUC-Gac-041580	Gasterosteus aculeatus	42.69	1.00e-96	347.00
IUUC-Ggo-045034	Gorilla gorilla	85.00	0.00e+00	910.00
IUUC-Hsa-046624	Homo sapiens	95.52	0.00e+00	1021.00
IUUC-Itr-048288	Ictidomys tridecemlineatus	78.29	0.00e+00	817.00
IUUC-Lch-049720	Latimeria chalumnae	49.62	2.00e-82	299.00
IUUC-Loc-052185	Lepisosteus oculatus	45.67	4.00e-107	381.00
IUUC-Laf-054079	Loxodonta africana	82.24	0.00e+00	827.00
IUUC-Mcc-055674	Macaca mulatta	97.59	0.00e+00	993.00
IUUC-Meu-056769	Macropus eugenii	54.63	1.00e-74	273.00
IUUC-Mga-060203	Meleagris gallopavo	58.52	7.00e-147	513.00
IUUC-Mmr-061492	Microcebus murinus	86.45	0.00e+00	853.00
IUUC-Mdo-063051	Monodelphis domestica	75.64	0.00e+00	802.00
IUUC-Mmu-063409	Mus musculus	77.10	0.00e+00	862.00
IUUC-Mpu-065907	Mustela putorius furo	77.72	0.00e+00	825.00
IUUC-Mlu-066957	Myotis lucifugus	82.50	0.00e+00	788.00
IUUC-Ncr-068766	Neurospora crassa	32.69	3.60e-01	30.00
IUUC-Nle-069973	Nomascus leucogenys	95.52	0.00e+00	1010.00
IUUC-Opr-071049	Ochotona princeps	78.69	0.00e+00	747.00
IUUC-Ont-071915	Oreochromis niloticus	44.04	2.00e-95	342.00
IUUC-Oan-072965	Ornithorhynchus anatinus	72.65	0.00e+00	770.00
IUUC-Ocu-074029	Oryctolagus cuniculus	75.46	0.00e+00	690.00
IUUC-Ola-087019	Oryzias latipes	42.44	3.00e-92	332.00
IUUC-Oga-088613	Otolemur garnettii	87.48	0.00e+00	899.00
IUUC-Oar-090386	Ovis aries	82.82	0.00e+00	893.00
IUUC-Ptr-091619	Pan troglodytes	95.34	0.00e+00	1018.00
IUUC-Psi-093214	Pelodiscus sinensis	63.57	3.00e-171	595.00
IUUC-Pfo-096901	Poecilia formosa	40.70	7.00e-86	311.00
IUUC-Pab-097560	Pongo abelii	86.55	0.00e+00	879.00
IUUC-Pca-100853	Procavia capensis	75.52	2.00e-127	449.00
IUUC-Pva-102255	Pteropus vampyrus	83.51	0.00e+00	791.00
IUUC-Rno-105812	Rattus norvegicus	79.50	0.00e+00	857.00
IUUC-Sha-107225	Sarcophilus harrisii	80.21	2.00e-158	551.00
IUUC-Sar-113736	Sorex araneus	74.86	7.00e-133	467.00
IUUC-Ssc-115422	Sus scrofa	83.53	0.00e+00	881.00
IUUC-Tgu-116924	Taeniopygia guttata	59.53	4.00e-152	531.00
IUUC-Tru-117695	Takifugu rubripes	39.42	5.00e-89	321.00
IUUC-Tsy-119090	Tarsius syrichta	85.32	3.00e-158	551.00
IUUC-Tni-120645	Tetraodon nigroviridis	41.88	2.00e-94	339.00
IUUC-Tbe-127970	Tupaia belangeri	68.56	0.00e+00	667.00
IUUC-Ttr-129244	Tursiops truncatus	82.99	0.00e+00	827.00
IUUC-Vpa-130313	Vicugna pacos	82.99	0.00e+00	798.00
IUUC-Xtr-132115	Xenopus tropicalis	45.95	6.00e-102	364.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence