iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-006962

UUCD1 version

UUC-ArT-00952

Ensembl Protein ID

AT5G15400.1

UniProt Accession

Q9LF41; UBE4_ARATH

Genbank Protein ID

CAC01739.1; AED92156.1; AT5G15400.1

Protein Name

Probable ubiquitin conjugation factor E4; Plant U-box protein 1; RING-type E3 ubiquitin transferase E4; U-box domain-containing protein 1; Ubiquitin-fusion degradation protein 2-like

Genbank Nucleotide ID

AL391143; CP002688; BX832575

Gene Name

PUB1; UFD2; At5g15400; T20K14_10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT5G15400	AT5G15400.1	AT5G15400.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	Mentha
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/U-box	U-box	24449689

Classification

Family	E-value	Score	Start	End
E3 activity/RING/U-box	1.20e-23	83.9	940	1013

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 1    evpeeflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceenss 74
           e+p+efl+pI+++lMrdPv+lp s+it+dr  I+++l s+++ +P++r++lt+++l+P ++l++ i++++++++s
   Q: 940  EIPDEFLDPIQYTLMRDPVILPsSRITVDRPIIQRHLLSDNH-DPFNRAHLTSDMLIPDIELKAKIDEFVKSHQS 1013
           69****************************************.*****************************987 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Ubiquitin-protein ligase that may function as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chain assembly on substrates monoubiquitinated by another E3 ubiquitin ligase.

Protein Sequence
(Fasta)

MATSKPQRSP AEIEDIILRK IFYVTLTEST DSDPRIVYLE MTAAEILSEG KELLLSRDLM 60
ERVLIDRLSG DFSDAEPPFP YLIGCHRRAY DESKKIQSMK DKNLRSEMEI VTKQAKKLAV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAGTAATT GTCTTAATAA GTATAAACGA CGTCGTTAGT AAGTACGACG TTTGCATATA 60
TCCTATATAG ACTTTTTGTC CAAGCTCAGG ACTTGCTAAA GCTCGTTCAG AGACTCCAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR019474--Ub_conjug_fac_E4_core
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51698--U_BOX

Pfam

PF04564--U-box
PF10408--Ufd2P_core

SMART

SM00504--Ubox

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0000209--P:protein polyubiquitination
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

ath:AT5G15400

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000585	Aegilops tauschii	66.30	0.00e+00	1075.00
IUUC-Aml-002396	Ailuropoda melanoleuca	30.05	9.00e-91	328.00
IUUC-Atr-002479	Amborella trichopoda	71.60	0.00e+00	1199.00
IUUC-Apl-003747	Anas platyrhynchos	29.60	2.00e-96	346.00
IUUC-Aca-004866	Anolis carolinensis	30.50	9.00e-96	344.00
IUUC-Aly-006300	Arabidopsis lyrata	97.21	0.00e+00	1917.00
IUUC-Ago-007880	Ashbya gossypii	27.21	8.00e-80	291.00
IUUC-Acl-008289	Aspergillus clavatus	29.42	1.00e-117	417.00
IUUC-Afl-008711	Aspergillus flavus	29.39	4.00e-116	412.00
IUUC-Afu-008766	Aspergillus fumigatus	29.68	2.00e-118	419.00
IUUC-Ani-009126	Aspergillus nidulans	29.39	1.00e-113	404.00
IUUC-Ang-009837	Aspergillus niger	29.92	1.00e-118	421.00
IUUC-Aor-009919	Aspergillus oryzae	28.61	2.00e-113	402.00
IUUC-Ate-010300	Aspergillus terreus	28.37	5.00e-108	385.00
IUUC-Ame-011355	Astyanax mexicanus	30.59	9.00e-99	354.00
IUUC-Bgr-011995	Blumeria graminis	29.17	5.00e-106	378.00
IUUC-Bta-013056	Bos taurus	30.16	1.00e-90	328.00
IUUC-Bci-013605	Botrytis cinerea	27.96	5.00e-97	348.00
IUUC-Bdi-015032	Brachypodium distachyon	61.72	0.00e+00	1159.00
IUUC-Bol-015172	Brassica oleracea	89.87	0.00e+00	1773.00
IUUC-Bra-016633	Brassica rapa	90.91	0.00e+00	1815.00
IUUC-Cel-018606	Caenorhabditis elegans	25.06	2.00e-57	216.00
IUUC-Cja-018872	Callithrix jacchus	31.11	2.00e-91	330.00
IUUC-Cfa-020045	Canis familiaris	30.05	8.00e-91	328.00
IUUC-Cpo-022309	Cavia porcellus	30.39	1.00e-92	334.00
IUUC-Cre-022726	Chlamydomonas reinhardtii	36.56	3.00e-58	218.00
IUUC-Csa-023765	Chlorocebus sabaeus	29.04	5.00e-83	302.00
IUUC-Cho-024614	Choloepus hoffmanni	37.64	3.00e-71	263.00
IUUC-Cin-025533	Ciona intestinalis	29.96	5.00e-108	385.00
IUUC-Csv-026081	Ciona savignyi	42.33	7.00e-33	132.00
IUUC-Cgl-026710	Colletotrichum gloeosporioides	28.78	1.00e-101	363.00
IUUC-Cne-027098	Cryptococcus neoformans	30.01	1.00e-117	417.00
IUUC-Cme-027352	Cyanidioschyzon merolae	30.50	2.00e-98	353.00
IUUC-Dre-027979	Danio rerio	29.49	2.00e-92	333.00
IUUC-Dno-029282	Dasypus novemcinctus	30.05	8.00e-91	328.00
IUUC-Dor-030421	Dipodomys ordii	29.93	2.00e-74	273.00
IUUC-Dse-031393	Dothistroma septosporum	27.79	2.00e-105	376.00
IUUC-Dme-031666	Drosophila melanogaster	28.34	5.00e-85	308.00
IUUC-Ete-032519	Echinops telfairi	38.55	5.00e-56	213.00
IUUC-Eca-033778	Equus caballus	29.86	3.00e-88	320.00
IUUC-Eeu-035315	Erinaceus europaeus	44.62	3.00e-32	134.00
IUUC-Fca-035658	Felis catus	30.01	2.00e-89	323.00
IUUC-Fal-037638	Ficedula albicollis	29.60	9.00e-97	348.00
IUUC-Fox-037909	Fusarium oxysporum	27.25	2.00e-93	337.00
IUUC-Fso-038406	Fusarium solani	28.30	2.00e-99	357.00
IUUC-Gmo-039379	Gadus morhua	29.30	2.00e-91	330.00
IUUC-Ggr-039851	Gaeumannomyces graminis	27.58	8.00e-91	328.00
IUUC-Gga-041136	Gallus gallus	30.12	3.00e-97	349.00
IUUC-Gac-041910	Gasterosteus aculeatus	29.95	1.00e-92	334.00
IUUC-Gma-043995	Glycine max	75.14	0.00e+00	1600.00
IUUC-Ggo-044685	Gorilla gorilla	31.20	6.00e-85	308.00
IUUC-Hsa-046880	Homo sapiens	30.35	2.00e-93	337.00
IUUC-Hvu-047157	Hordeum vulgare	66.18	0.00e+00	1053.00
IUUC-Itr-048469	Ictidomys tridecemlineatus	36.51	2.00e-74	272.00
IUUC-Kpa-049211	Komagataella pastoris	33.11	3.00e-66	246.00
IUUC-Lch-050534	Latimeria chalumnae	30.14	2.00e-95	343.00
IUUC-Lpe-051022	Leersia perrieri	63.09	0.00e+00	1158.00
IUUC-Loc-052622	Lepisosteus oculatus	30.34	1.00e-91	331.00
IUUC-Lma-053241	Leptosphaeria maculans	28.47	2.00e-104	373.00
IUUC-Laf-053646	Loxodonta africana	30.28	3.00e-91	330.00
IUUC-Mcc-055588	Macaca mulatta	31.11	2.00e-91	330.00
IUUC-Meu-055991	Macropus eugenii	28.60	2.00e-81	296.00
IUUC-Mor-057064	Magnaporthe oryzae	26.92	1.00e-98	354.00
IUUC-Mpo-057452	Magnaporthe poae	27.87	7.00e-93	335.00
IUUC-Mtr-058016	Medicago truncatula	73.11	0.00e+00	1563.00
IUUC-Mla-058887	Melampsora laricipopulina	33.78	1.00e-115	410.00
IUUC-Mga-059497	Meleagris gallopavo	29.77	2.00e-96	347.00
IUUC-Mvi-060343	Microbotryum violaceum	30.21	5.00e-114	405.00
IUUC-Mmr-061173	Microcebus murinus	33.99	2.00e-78	286.00
IUUC-Mdo-062102	Monodelphis domestica	30.28	4.00e-94	339.00
IUUC-Mmu-063223	Mus musculus	29.93	7.00e-92	332.00
IUUC-Mac-065531	Musa acuminata	68.08	0.00e+00	1406.00
IUUC-Mpu-066444	Mustela putorius furo	28.76	2.00e-79	290.00
IUUC-Mlu-068018	Myotis lucifugus	30.24	2.00e-90	327.00
IUUC-Nfi-068590	Neosartorya fischeri	29.78	9.00e-121	427.00
IUUC-Ncr-068901	Neurospora crassa	26.94	3.00e-97	349.00
IUUC-Nle-069605	Nomascus leucogenys	30.76	5.00e-89	322.00
IUUC-Opr-071011	Ochotona princeps	37.16	3.00e-51	196.00
IUUC-Ont-072304	Oreochromis niloticus	29.47	1.00e-87	318.00
IUUC-Oan-073410	Ornithorhynchus anatinus	33.93	4.00e-83	301.00
IUUC-Ocu-074910	Oryctolagus cuniculus	30.00	6.00e-93	335.00
IUUC-Oba-075073	Oryza barthii	63.23	0.00e+00	1178.00
IUUC-Obr-076452	Oryza brachyantha	61.91	0.00e+00	1183.00
IUUC-Ogl-077141	Oryza glaberrima	62.34	0.00e+00	1238.00
IUUC-Ogu-078116	Oryza glumaepatula	62.49	0.00e+00	1234.00
IUUC-Oin-079066	Oryza indica	62.44	0.00e+00	1238.00
IUUC-Olo-080253	Oryza longistaminata	64.31	0.00e+00	1080.00
IUUC-Ome-081263	Oryza meridionalis	62.46	0.00e+00	1233.00
IUUC-Oni-082019	Oryza nivara	62.39	0.00e+00	1233.00
IUUC-Opu-083558	Oryza punctata	62.69	0.00e+00	1237.00
IUUC-Oru-085002	Oryza rufipogon	62.34	0.00e+00	1238.00
IUUC-Osa-085980	Oryza sativa	62.36	0.00e+00	1252.00
IUUC-Ola-086323	Oryzias latipes	30.41	1.00e-91	331.00
IUUC-Olu-087901	Ostreococcus lucimarinus	37.63	9.00e-160	556.00
IUUC-Oga-087969	Otolemur garnettii	30.94	1.00e-84	308.00
IUUC-Oar-090020	Ovis aries	30.16	7.00e-91	328.00
IUUC-Ptr-091589	Pan troglodytes	30.39	2.00e-93	337.00
IUUC-Pan-092271	Papio anubis	28.72	5.00e-85	308.00
IUUC-Psi-093013	Pelodiscus sinensis	29.42	4.00e-95	342.00
IUUC-Pma-094627	Petromyzon marinus	35.18	1.00e-76	279.00
IUUC-Pno-094840	Phaeosphaeria nodorum	29.03	9.00e-117	414.00
IUUC-Ppa-095989	Physcomitrella patens	56.48	0.00e+00	1060.00
IUUC-Pfo-096436	Poecilia formosa	30.23	2.00e-93	337.00
IUUC-Pab-098275	Pongo abelii	34.65	1.00e-81	297.00
IUUC-Pop-100005	Populus trichocarpa	73.92	0.00e+00	1557.00
IUUC-Pca-100762	Procavia capensis	30.06	2.00e-77	283.00
IUUC-Ppe-101230	Prunus persica	77.26	0.00e+00	1623.00
IUUC-Pva-102459	Pteropus vampyrus	30.98	1.00e-89	324.00
IUUC-Pgr-103366	Puccinia graminis	31.05	6.00e-115	408.00
IUUC-Ptt-104001	Puccinia triticina	26.48	1.00e-32	134.00
IUUC-Pte-104084	Pyrenophora teres	28.11	1.00e-112	400.00
IUUC-Pyt-104484	Pyrenophora triticirepentis	28.04	1.00e-113	404.00
IUUC-Rno-105719	Rattus norvegicus	30.12	4.00e-94	338.00
IUUC-Sce-106135	Saccharomyces cerevisiae	37.05	4.00e-69	256.00
IUUC-Sha-106760	Sarcophilus harrisii	30.51	1.00e-93	337.00
IUUC-Sja-107698	Schizosaccharomyces japonicus	28.91	5.00e-95	342.00
IUUC-Spo-108076	Schizosaccharomyces pombe	27.68	2.00e-88	319.00
IUUC-Ssl-108624	Sclerotinia sclerotiorum	28.78	2.00e-103	369.00
IUUC-Smo-109042	Selaginella moellendorffii	54.06	0.00e+00	1026.00
IUUC-Sit-109949	Setaria italica	62.20	0.00e+00	1151.00
IUUC-Sly-110973	Solanum lycopersicum	68.39	0.00e+00	1227.00
IUUC-Stu-112372	Solanum tuberosum	75.48	0.00e+00	1554.00
IUUC-Sar-113131	Sorex araneus	35.79	6.00e-63	235.00
IUUC-Sbi-113828	Sorghum bicolor	63.16	0.00e+00	1202.00
IUUC-Sre-114967	Sporisorium reilianum	32.11	2.00e-111	396.00
IUUC-Ssc-115841	Sus scrofa	30.88	3.00e-85	309.00
IUUC-Tgu-117290	Taeniopygia guttata	30.42	6.00e-93	335.00
IUUC-Tru-118193	Takifugu rubripes	29.89	1.00e-90	327.00
IUUC-Tsy-118926	Tarsius syrichta	30.16	2.00e-91	330.00
IUUC-Tni-120862	Tetraodon nigroviridis	29.97	1.00e-92	334.00
IUUC-Tca-121096	Theobroma cacao	75.19	0.00e+00	1536.00
IUUC-Tre-122104	Trichoderma reesei	27.33	3.00e-94	340.00
IUUC-Tvi-122345	Trichoderma virens	27.35	8.00e-95	342.00
IUUC-Tae-124607	Triticum aestivum	61.75	0.00e+00	1101.00
IUUC-Tur-126056	Triticum urartu	66.18	0.00e+00	1074.00
IUUC-Tme-127074	Tuber melanosporum	28.47	9.00e-97	347.00
IUUC-Tbe-127533	Tupaia belangeri	31.11	9.00e-92	331.00
IUUC-Ttr-128757	Tursiops truncatus	29.42	9.00e-88	318.00
IUUC-Uma-129550	Ustilago maydis	31.28	6.00e-108	385.00
IUUC-Vda-129901	Verticillium dahliae	28.78	2.00e-104	373.00
IUUC-Vpa-130215	Vicugna pacos	28.31	3.00e-83	302.00
IUUC-Vvi-130891	Vitis vinifera	77.52	0.00e+00	1592.00
IUUC-Xtr-132364	Xenopus tropicalis	30.09	8.00e-93	335.00
IUUC-Xma-133772	Xiphophorus maculatus	30.23	9.00e-93	335.00
IUUC-Yli-134506	Yarrowia lipolytica	26.65	2.00e-87	317.00
IUUC-Zma-135557	Zea mays	63.13	0.00e+00	1139.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence