iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050095

Ensembl Protein ID

ENSLACP00000020141.2

UniProt Accession

H3BE20; H3BE20_LATCH

Genbank Protein ID

ENSLACP00000020141

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01011866

Gene Name

CBL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000017700.2	ENSLACT00000020279.2	ENSLACP00000020141.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.90e-08	32.6	363	402

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pCgH+++++Cl +w    + +s  + CP Cr
   Q: 363  CKICAENDKD-VKIEPCGHLMCTSCLTAW----Q-ESEGQGCPFCR 402
           99********.******************....5.555555****8 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MAANTKKGGG LIGLVKDAFQ PHHHHLHHQP GTVDKKTVEK SWKLMDKVVR LCQNPKLALK 60
NSPPYILDLL PDTYQHLRSI LSRYEGKMET LGENEYFRVF MENLLKKTKQ TILLFKEGKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCTGTT CCGTGTTCTG AAGTGCGGCG TCGATTCCGC TCGCCAGCCG GAAACCTGCA 60
GGTTGCTCCG AAAGGGGGAT TGCAATGGGC AAGCTGGTGC GCGAGCGAGC GCTCGGGACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR015940--UBA
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS50030--UBA
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING
SM00165--UBA

Gene Ontology

GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0023051--P:regulation of signaling

KEGG

lcm:102345712

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002357	Ailuropoda melanoleuca	74.48	0.00e+00	1129.00
IUUC-Apl-004041	Anas platyrhynchos	76.97	0.00e+00	1193.00
IUUC-Aca-004899	Anolis carolinensis	74.08	0.00e+00	1119.00
IUUC-Ame-010746	Astyanax mexicanus	62.35	0.00e+00	641.00
IUUC-Bta-012759	Bos taurus	74.22	0.00e+00	1176.00
IUUC-Cja-019207	Callithrix jacchus	74.67	0.00e+00	1202.00
IUUC-Cfa-020897	Canis familiaris	73.53	0.00e+00	1159.00
IUUC-Cpo-021453	Cavia porcellus	73.24	0.00e+00	1157.00
IUUC-Csa-023136	Chlorocebus sabaeus	74.06	0.00e+00	1186.00
IUUC-Cho-024282	Choloepus hoffmanni	67.40	0.00e+00	978.00
IUUC-Cin-025574	Ciona intestinalis	70.99	6.00e-178	616.00
IUUC-Csv-025938	Ciona savignyi	69.37	1.00e-172	598.00
IUUC-Dre-027644	Danio rerio	70.56	0.00e+00	1037.00
IUUC-Dno-030025	Dasypus novemcinctus	74.54	0.00e+00	1133.00
IUUC-Dor-031040	Dipodomys ordii	68.44	1.00e-177	617.00
IUUC-Dme-032213	Drosophila melanogaster	73.98	0.00e+00	643.00
IUUC-Eca-033900	Equus caballus	75.40	0.00e+00	1157.00
IUUC-Eeu-035142	Erinaceus europaeus	74.32	0.00e+00	792.00
IUUC-Fca-035455	Felis catus	74.00	0.00e+00	1184.00
IUUC-Fal-037182	Ficedula albicollis	91.56	0.00e+00	857.00
IUUC-Gmo-038698	Gadus morhua	87.30	0.00e+00	853.00
IUUC-Gga-040438	Gallus gallus	77.33	0.00e+00	1211.00
IUUC-Gac-042166	Gasterosteus aculeatus	73.62	0.00e+00	894.00
IUUC-Ggo-045618	Gorilla gorilla	74.70	0.00e+00	1197.00
IUUC-Hsa-046177	Homo sapiens	74.59	0.00e+00	1192.00
IUUC-Itr-048795	Ictidomys tridecemlineatus	81.30	0.00e+00	827.00
IUUC-Loc-052570	Lepisosteus oculatus	74.32	0.00e+00	1118.00
IUUC-Laf-054008	Loxodonta africana	74.04	0.00e+00	1187.00
IUUC-Mcc-054676	Macaca mulatta	74.06	0.00e+00	1187.00
IUUC-Meu-056045	Macropus eugenii	60.82	1.00e-154	540.00
IUUC-Mga-059239	Meleagris gallopavo	76.52	0.00e+00	1232.00
IUUC-Mmr-060907	Microcebus murinus	72.69	0.00e+00	1178.00
IUUC-Mdo-062595	Monodelphis domestica	76.68	0.00e+00	1171.00
IUUC-Mmu-063725	Mus musculus	75.06	0.00e+00	1222.00
IUUC-Mpu-066771	Mustela putorius furo	73.86	0.00e+00	1165.00
IUUC-Mlu-067206	Myotis lucifugus	78.44	0.00e+00	894.00
IUUC-Nle-069285	Nomascus leucogenys	71.85	0.00e+00	1116.00
IUUC-Opr-071026	Ochotona princeps	74.83	0.00e+00	1169.00
IUUC-Ont-071954	Oreochromis niloticus	71.61	0.00e+00	1063.00
IUUC-Ocu-074657	Oryctolagus cuniculus	75.99	0.00e+00	1148.00
IUUC-Ola-087165	Oryzias latipes	68.44	0.00e+00	1079.00
IUUC-Oga-088198	Otolemur garnettii	67.53	0.00e+00	1072.00
IUUC-Oar-090258	Ovis aries	74.51	0.00e+00	1127.00
IUUC-Ptr-090710	Pan troglodytes	74.59	0.00e+00	1192.00
IUUC-Pan-092785	Papio anubis	74.06	0.00e+00	1186.00
IUUC-Pma-094249	Petromyzon marinus	74.72	2.00e-121	428.00
IUUC-Pfo-096990	Poecilia formosa	89.13	0.00e+00	823.00
IUUC-Pab-098526	Pongo abelii	74.45	0.00e+00	1190.00
IUUC-Pop-099439	Populus trichocarpa	40.00	2.00e-06	50.80
IUUC-Pca-100844	Procavia capensis	61.69	1.00e-155	543.00
IUUC-Pva-102352	Pteropus vampyrus	90.09	0.00e+00	827.00
IUUC-Rno-105876	Rattus norvegicus	74.42	0.00e+00	1194.00
IUUC-Sha-107588	Sarcophilus harrisii	75.73	0.00e+00	1035.00
IUUC-Sar-112959	Sorex araneus	72.36	0.00e+00	1143.00
IUUC-Ssc-115261	Sus scrofa	74.78	0.00e+00	1190.00
IUUC-Tgu-116580	Taeniopygia guttata	74.97	0.00e+00	1149.00
IUUC-Tru-118731	Takifugu rubripes	70.28	0.00e+00	1071.00
IUUC-Tsy-118982	Tarsius syrichta	63.00	0.00e+00	748.00
IUUC-Tni-120725	Tetraodon nigroviridis	68.01	0.00e+00	1036.00
IUUC-Tbe-128018	Tupaia belangeri	83.71	0.00e+00	982.00
IUUC-Ttr-128927	Tursiops truncatus	75.47	0.00e+00	1241.00
IUUC-Vpa-130369	Vicugna pacos	73.78	0.00e+00	1107.00
IUUC-Xtr-132474	Xenopus tropicalis	71.84	0.00e+00	1108.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence