iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-002240

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01043318

Gene Name

TOPORS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000003832.1	ENSAMET00000004197.1	ENSAMEP00000004033.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.40e-09	37.2	103	142

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl++f++  ++ +C H f++ C+q w      s++++ CPlC+
   Q: 103  CPICLDRFDNVSYLDRCLHKFCFRCVQEW------SKNKAECPLCK 142
           **********999999*************......**********7 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

QGSQQPPGSP LSREEGEAPP PAPAPEGRRR SRRVRLRGSC RHRPSFLGRQ ELGTSAPAGT 60
APVSSEIMAS AAKEFKMDNF SPKAGTSKLQ QTVPADASPD SKCPICLDRF DNVSYLDRCL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGGGTCGC AGCAGCCGCC GGGGTCTCCG CTGTCTCGCG AGGAGGGTGA AGCGCCCCCT 60
CCTGCTCCCG CTCCTGAGGG CCGGCGGAGA AGTCGCCGGG TACGCCTTCG CGGATCCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000930--C:gamma-tubulin complex
GO:0016607--C:nuclear speck
GO:0032391--C:photoreceptor connecting cilium
GO:0016605--C:PML body
GO:0000922--C:spindle pole
GO:0000151--C:ubiquitin ligase complex
GO:0003823--F:antigen binding
GO:0003677--F:DNA binding
GO:0019789--F:SUMO transferase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0051457--P:maintenance of protein location in nucleus
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0042127--P:regulation of cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000940	Aegilops tauschii	36.76	2.00e-09	55.80
IUUC-Atr-002964	Amborella trichopoda	32.32	9.00e-12	63.50
IUUC-Apl-003666	Anas platyrhynchos	61.66	3.00e-141	495.00
IUUC-Aca-005305	Anolis carolinensis	62.18	3.00e-148	519.00
IUUC-Aly-005926	Arabidopsis lyrata	36.17	2.00e-10	59.70
IUUC-Ath-007668	Arabidopsis thaliana	22.26	3.00e-08	52.40
IUUC-Ame-011109	Astyanax mexicanus	52.16	4.00e-114	405.00
IUUC-Bta-012637	Bos taurus	90.19	0.00e+00	913.00
IUUC-Bdi-014270	Brachypodium distachyon	40.00	2.00e-11	62.80
IUUC-Bol-015115	Brassica oleracea	27.74	3.00e-08	52.40
IUUC-Bra-017451	Brassica rapa	31.25	3.00e-08	52.40
IUUC-Cja-019105	Callithrix jacchus	92.01	0.00e+00	970.00
IUUC-Cfa-021203	Canis familiaris	98.46	0.00e+00	979.00
IUUC-Cpo-022335	Cavia porcellus	84.83	0.00e+00	842.00
IUUC-Csa-023870	Chlorocebus sabaeus	91.67	0.00e+00	943.00
IUUC-Cho-024870	Choloepus hoffmanni	91.21	0.00e+00	867.00
IUUC-Cne-026788	Cryptococcus neoformans	33.85	4.00e-07	50.40
IUUC-Dre-027535	Danio rerio	53.88	3.00e-120	426.00
IUUC-Dno-028963	Dasypus novemcinctus	91.33	0.00e+00	860.00
IUUC-Dor-030239	Dipodomys ordii	88.73	0.00e+00	781.00
IUUC-Dme-031941	Drosophila melanogaster	32.19	4.00e-36	147.00
IUUC-Ete-032300	Echinops telfairi	83.93	0.00e+00	1126.00
IUUC-Eca-033690	Equus caballus	94.27	0.00e+00	909.00
IUUC-Eeu-035257	Erinaceus europaeus	89.16	0.00e+00	882.00
IUUC-Fca-036383	Felis catus	96.57	0.00e+00	973.00
IUUC-Fal-037209	Ficedula albicollis	69.88	2.00e-160	560.00
IUUC-Gmo-039416	Gadus morhua	53.63	4.00e-121	427.00
IUUC-Gga-041267	Gallus gallus	70.61	1.00e-173	603.00
IUUC-Gac-042227	Gasterosteus aculeatus	51.96	2.00e-116	412.00
IUUC-Gma-043386	Glycine max	32.23	3.00e-12	65.50
IUUC-Ggo-044445	Gorilla gorilla	91.50	0.00e+00	956.00
IUUC-Hsa-045844	Homo sapiens	91.67	0.00e+00	958.00
IUUC-Hvu-047531	Hordeum vulgare	46.00	7.00e-11	58.20
IUUC-Itr-048818	Ictidomys tridecemlineatus	91.67	0.00e+00	928.00
IUUC-Lch-050031	Latimeria chalumnae	64.88	2.00e-166	579.00
IUUC-Lpe-051274	Leersia perrieri	37.74	9.00e-09	53.90
IUUC-Loc-052944	Lepisosteus oculatus	57.34	3.00e-140	492.00
IUUC-Laf-053820	Loxodonta africana	92.96	0.00e+00	860.00
IUUC-Mcc-054800	Macaca mulatta	91.68	0.00e+00	945.00
IUUC-Meu-056806	Macropus eugenii	73.98	0.00e+00	640.00
IUUC-Mtr-058378	Medicago truncatula	34.91	3.00e-12	65.50
IUUC-Mla-059017	Melampsora laricipopulina	36.07	4.00e-09	55.80
IUUC-Mvi-060417	Microbotryum violaceum	24.38	5.00e-16	80.10
IUUC-Mmr-061481	Microcebus murinus	92.86	0.00e+00	909.00
IUUC-Mdo-062219	Monodelphis domestica	81.45	5.00e-108	385.00
IUUC-Mmu-064138	Mus musculus	86.63	0.00e+00	815.00
IUUC-Mac-064635	Musa acuminata	38.57	6.00e-11	59.70
IUUC-Mlu-067088	Myotis lucifugus	91.00	0.00e+00	907.00
IUUC-Nle-069862	Nomascus leucogenys	91.69	0.00e+00	953.00
IUUC-Opr-071076	Ochotona princeps	90.91	0.00e+00	809.00
IUUC-Ont-072225	Oreochromis niloticus	51.25	1.00e-111	397.00
IUUC-Oan-073069	Ornithorhynchus anatinus	65.83	6.00e-158	550.00
IUUC-Ocu-074826	Oryctolagus cuniculus	91.00	0.00e+00	923.00
IUUC-Oba-075429	Oryza barthii	37.68	1.00e-10	60.10
IUUC-Obr-076084	Oryza brachyantha	36.23	4.00e-10	58.50
IUUC-Ogl-077444	Oryza glaberrima	37.68	1.00e-10	60.10
IUUC-Ogu-078603	Oryza glumaepatula	37.68	1.00e-10	60.10
IUUC-Oin-079777	Oryza indica	37.68	1.00e-10	59.70
IUUC-Oni-082396	Oryza nivara	37.68	1.00e-10	60.10
IUUC-Opu-083698	Oryza punctata	36.62	7.00e-10	57.80
IUUC-Oru-084305	Oryza rufipogon	37.68	1.00e-10	60.10
IUUC-Ola-087377	Oryzias latipes	54.86	3.00e-109	388.00
IUUC-Oga-088059	Otolemur garnettii	88.95	0.00e+00	918.00
IUUC-Oar-089592	Ovis aries	89.47	0.00e+00	884.00
IUUC-Ptr-091233	Pan troglodytes	91.50	0.00e+00	955.00
IUUC-Pan-092743	Papio anubis	91.84	0.00e+00	946.00
IUUC-Psi-093669	Pelodiscus sinensis	59.64	0.00e+00	841.00
IUUC-Ppa-095668	Physcomitrella patens	26.67	4.00e-23	102.00
IUUC-Pfo-096706	Poecilia formosa	53.66	9.00e-106	377.00
IUUC-Pop-099119	Populus trichocarpa	23.87	3.00e-12	65.50
IUUC-Pca-100967	Procavia capensis	89.64	0.00e+00	792.00
IUUC-Ppe-101958	Prunus persica	38.96	5.00e-10	58.20
IUUC-Pva-102982	Pteropus vampyrus	94.22	0.00e+00	925.00
IUUC-Pgr-103551	Puccinia graminis	38.46	8.00e-09	53.90
IUUC-Ptt-103977	Puccinia triticina	33.33	6.00e-08	50.80
IUUC-Rno-105730	Rattus norvegicus	85.81	0.00e+00	778.00
IUUC-Sha-106588	Sarcophilus harrisii	70.33	2.00e-180	626.00
IUUC-Sja-107735	Schizosaccharomyces japonicus	35.38	2.00e-07	49.30
IUUC-Smo-109039	Selaginella moellendorffii	25.00	7.00e-19	88.20
IUUC-Sly-111835	Solanum lycopersicum	42.37	1.00e-08	55.50
IUUC-Stu-111938	Solanum tuberosum	40.35	3.00e-06	45.40
IUUC-Sar-113622	Sorex araneus	88.67	6.00e-159	555.00
IUUC-Sre-115041	Sporisorium reilianum	37.84	1.00e-09	57.40
IUUC-Ssc-115244	Sus scrofa	94.05	0.00e+00	876.00
IUUC-Tgu-117180	Taeniopygia guttata	63.95	2.00e-167	582.00
IUUC-Tru-118393	Takifugu rubripes	53.36	1.00e-120	427.00
IUUC-Tsy-119408	Tarsius syrichta	92.15	0.00e+00	913.00
IUUC-Tni-120664	Tetraodon nigroviridis	53.45	1.00e-120	427.00
IUUC-Tca-121712	Theobroma cacao	27.38	6.00e-17	81.30
IUUC-Tae-122787	Triticum aestivum	38.57	1.00e-10	60.50
IUUC-Tbe-127301	Tupaia belangeri	84.01	0.00e+00	799.00
IUUC-Ttr-128204	Tursiops truncatus	93.63	0.00e+00	948.00
IUUC-Uma-129420	Ustilago maydis	43.06	8.00e-10	57.80
IUUC-Vpa-130297	Vicugna pacos	93.24	0.00e+00	894.00
IUUC-Vvi-131157	Vitis vinifera	25.75	2.00e-17	83.20
IUUC-Xtr-132845	Xenopus tropicalis	65.91	1.00e-170	593.00
IUUC-Xma-133439	Xiphophorus maculatus	53.39	2.00e-107	383.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence