iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010732

Ensembl Protein ID

ENSAMXP00000026008.1

UniProt Accession

W5LSQ3; W5LSQ3_ASTMX

Genbank Protein ID

ENSAMXP00000026008

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01022700

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000025302.1	ENSAMXT00000026028.1	ENSAMXP00000026008.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.40e-14	53.9	486	530

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 6    llrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           + r++p+SLqh CR +I +c++++++   ++LP+P++Lk++L++++y+
   Q: 486  IHRTQPFSLQHVCRAVISSCTTYDGI---SALPIPNALKEHLKEYHYK 530
           5689**********************...****************985 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MSTDGGDRGK ERERGARPKA RQSRSEERQD GGRRKGSRGK RKGHLAHEPA SERPVSDGFE 60
YGDLLNRFES GSGSSSSPVR ERRWRQVLGS SSSLLSERAS AKPALSNSFS ADQSVADTGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTACGG ACGGAGGAGA CCGTGGGAAA GAACGAGAGC GAGGGGCACG TCCCAAGGCA 60
CGACAGAGTC GCTCGGAAGA GCGTCAGGAT GGAGGGAGAC GTAAAGGAAG CAGGGGGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR022252--SOCS4/SOCS5_dom
IPR028420--SOCS5
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF12610--SOCS
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007259--P:JAK-STAT cascade
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-012503	Bos taurus	79.65	3.00e-86	312.00
IUUC-Bol-016597	Brassica oleracea	41.03	5.70e-02	32.70
IUUC-Cja-019284	Callithrix jacchus	79.65	2.00e-86	313.00
IUUC-Dno-029961	Dasypus novemcinctus	79.65	2.00e-86	312.00
IUUC-Dme-031965	Drosophila melanogaster	70.18	6.00e-72	265.00
IUUC-Gac-041931	Gasterosteus aculeatus	70.57	4.00e-153	534.00
IUUC-Loc-051791	Lepisosteus oculatus	63.91	8.00e-161	560.00
IUUC-Ont-072537	Oreochromis niloticus	65.23	0.00e+00	641.00
IUUC-Oar-090330	Ovis aries	79.65	3.00e-86	312.00
IUUC-Pfo-097139	Poecilia formosa	64.94	2.00e-176	612.00
IUUC-Pop-098820	Populus trichocarpa	44.12	5.60e-02	32.30
IUUC-Ssc-115821	Sus scrofa	79.65	3.00e-86	312.00
IUUC-Tsy-118979	Tarsius syrichta	79.65	8.00e-86	309.00
IUUC-Vvi-131327	Vitis vinifera	45.95	3.20e-02	32.70

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence