iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-098602

Ensembl Protein ID

ENSPPYP00000013328.1

UniProt Accession

H2P4S5; H2P4S5_PONAB

Genbank Protein ID

ENSPPYP00000013328

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01006344

Gene Name

PPARA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000011942.1	ENSPPYT00000013867.1	ENSPPYP00000013328.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	93.25	0.00e+00	826.00	IUUC-Hsa-046893

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pongo abelii

Protein Sequence
(Fasta)

MVDTESPLCP LSPLEAGDLE SPLSEEFLQE MGNIQEISQS IGEDSSGSFG FTEYKYLGSC 60
PGSYGSIIKD TLSPASSPSS VTYPVVPGSV DESPSGALNI ECRICGDKAS GYHYGVHACE 120

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Nucleotide Sequence
(Fasta)

ATGGTGGACA CGGAAAGCCC GCTCTGCCCC CTCTCCCCAC TCGAGGCTGG CGATCTAGAG 60
AGCCCGTTAT CTGAAGAATT CCTGCAAGAA ATGGGAAACA TCCAAGAGAT TTCGCAATCC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003076--1Cnucl_rcpt_A
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01289--PROXISOMPAAR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008144--F:drug binding
GO:0008289--F:lipid binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001190--F:transcriptional activator activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0070166--P:enamel mineralization
GO:0008544--P:epidermis development
GO:0006631--P:fatty acid metabolic process
GO:0032099--P:negative regulation of appetite
GO:0010887--P:negative regulation of cholesterol storage
GO:0050728--P:negative regulation of inflammatory response
GO:1903038--P:negative regulation of leukocyte cell-cell adhesion
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:1902894--P:negative regulation of pri-miRNA transcription from RNA polymerase II promoter
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0046321--P:positive regulation of fatty acid oxidation
GO:0045722--P:positive regulation of gluconeogenesis
GO:0072366--P:regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
GO:0042752--P:regulation of circadian rhythm
GO:0072363--P:regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
GO:0072369--P:regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002222	Ailuropoda melanoleuca	87.61	0.00e+00	842.00
IUUC-Apl-003330	Anas platyrhynchos	82.22	0.00e+00	768.00
IUUC-Aca-004598	Anolis carolinensis	79.54	0.00e+00	741.00
IUUC-Ame-011508	Astyanax mexicanus	69.89	0.00e+00	641.00
IUUC-Bta-012621	Bos taurus	88.40	0.00e+00	812.00
IUUC-Cja-019688	Callithrix jacchus	90.93	0.00e+00	828.00
IUUC-Cfa-020859	Canis familiaris	88.19	0.00e+00	845.00
IUUC-Cpo-021607	Cavia porcellus	83.33	0.00e+00	762.00
IUUC-Csa-023313	Chlorocebus sabaeus	92.62	0.00e+00	840.00
IUUC-Cho-024741	Choloepus hoffmanni	77.43	0.00e+00	672.00
IUUC-Cgl-026615	Colletotrichum gloeosporioides	32.20	3.10e-01	27.70
IUUC-Dre-027446	Danio rerio	69.12	3.00e-180	624.00
IUUC-Dno-029173	Dasypus novemcinctus	86.71	0.00e+00	794.00
IUUC-Dor-030581	Dipodomys ordii	84.57	0.00e+00	738.00
IUUC-Dme-031794	Drosophila melanogaster	34.60	4.00e-55	210.00
IUUC-Ete-032330	Echinops telfairi	84.81	0.00e+00	804.00
IUUC-Eca-033712	Equus caballus	88.82	0.00e+00	805.00
IUUC-Fca-036555	Felis catus	88.87	0.00e+00	848.00
IUUC-Fal-036677	Ficedula albicollis	81.86	0.00e+00	765.00
IUUC-Gmo-039240	Gadus morhua	77.57	6.00e-170	589.00
IUUC-Gga-040473	Gallus gallus	82.70	0.00e+00	774.00
IUUC-Gac-041872	Gasterosteus aculeatus	68.83	0.00e+00	647.00
IUUC-Ggo-045226	Gorilla gorilla	93.25	0.00e+00	848.00
IUUC-Hsa-046893	Homo sapiens	93.25	0.00e+00	848.00
IUUC-Itr-048952	Ictidomys tridecemlineatus	86.71	0.00e+00	793.00
IUUC-Lch-050116	Latimeria chalumnae	74.68	0.00e+00	701.00
IUUC-Loc-052131	Lepisosteus oculatus	78.27	0.00e+00	634.00
IUUC-Laf-054323	Loxodonta africana	88.61	0.00e+00	813.00
IUUC-Mcc-054841	Macaca mulatta	92.83	0.00e+00	838.00
IUUC-Meu-056833	Macropus eugenii	77.00	0.00e+00	677.00
IUUC-Mga-059995	Meleagris gallopavo	74.06	0.00e+00	674.00
IUUC-Mdo-061954	Monodelphis domestica	84.96	0.00e+00	704.00
IUUC-Mmu-064295	Mus musculus	86.71	0.00e+00	769.00
IUUC-Mpu-066216	Mustela putorius furo	88.61	0.00e+00	848.00
IUUC-Nle-069970	Nomascus leucogenys	93.04	0.00e+00	845.00
IUUC-Ont-071594	Oreochromis niloticus	69.67	0.00e+00	639.00
IUUC-Oan-073501	Ornithorhynchus anatinus	85.02	0.00e+00	694.00
IUUC-Ocu-074634	Oryctolagus cuniculus	79.96	0.00e+00	761.00
IUUC-Oni-082926	Oryza nivara	29.41	1.50e-02	30.40
IUUC-Ola-086585	Oryzias latipes	75.72	2.00e-168	585.00
IUUC-Oga-088738	Otolemur garnettii	90.51	0.00e+00	818.00
IUUC-Oar-090453	Ovis aries	87.97	0.00e+00	808.00
IUUC-Ptr-091518	Pan troglodytes	93.04	0.00e+00	842.00
IUUC-Pan-092006	Papio anubis	93.04	0.00e+00	842.00
IUUC-Psi-093352	Pelodiscus sinensis	80.96	0.00e+00	765.00
IUUC-Pfo-096060	Poecilia formosa	68.41	0.00e+00	627.00
IUUC-Pva-102175	Pteropus vampyrus	83.12	0.00e+00	785.00
IUUC-Rno-105283	Rattus norvegicus	86.29	0.00e+00	770.00
IUUC-Sce-106436	Saccharomyces cerevisiae	29.03	8.00e-03	32.00
IUUC-Sha-106560	Sarcophilus harrisii	86.29	0.00e+00	795.00
IUUC-Ssc-115266	Sus scrofa	87.97	0.00e+00	852.00
IUUC-Tgu-116778	Taeniopygia guttata	81.86	0.00e+00	766.00
IUUC-Tru-118436	Takifugu rubripes	68.83	0.00e+00	638.00
IUUC-Tsy-119642	Tarsius syrichta	77.22	0.00e+00	672.00
IUUC-Tni-119859	Tetraodon nigroviridis	68.62	0.00e+00	632.00
IUUC-Tvi-122624	Trichoderma virens	30.91	1.30e-01	28.90
IUUC-Tbe-127464	Tupaia belangeri	86.92	0.00e+00	832.00
IUUC-Ttr-129307	Tursiops truncatus	84.63	0.00e+00	759.00
IUUC-Xma-133882	Xiphophorus maculatus	68.62	0.00e+00	627.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence